pentamidine has been researched along with Recrudescence in 104 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the outcome of pretreatment of Acanthamoeba keratitis with intravenous pentamidine (IVP) before therapeutic keratoplasty (TKP)." | 7.81 | Treatment of acanthamoeba keratitis with intravenous pentamidine before therapeutic keratoplasty. ( Goins, KM; Greiner, MA; Kitzmann, AS; Sacher, BA; Sutphin, JE; Wagoner, MD, 2015) |
| "Aerosolized pentamidine prophylaxis for Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS) may predispose these patients to recurrent apical Pneumocystis infection." | 7.68 | Spontaneous pneumothorax in AIDS patients with recurrent Pneumocystis carinii pneumonia despite aerosolized pentamidine prophylaxis. ( Haggerty, MF; Luyckx, BA; Murphy, TF; Shanley, DJ, 1991) |
| "In order to determine the possible effect of aerosolized pentamidine on the cellular composition of the bronchoalveolar lavage fluid in HIV-infected patients, differential counts of 22 consecutive patients who had been rebronchoscopied after 3-19 months were reviewed." | 7.68 | Pentamidine aerosol increases the number of alveolar macrophages in HIV-infected patients. ( Don, M; Eckert, G; Hilger, HH; Pothoff, G; Schell-Frederick, E; Wassermann, K, 1991) |
| "His episodes of torsade de pointes were refractory to the usual therapy." | 5.28 | Torsade de pointes after inhaled pentamidine. ( Coodley, G; Engrav, MB; Magnusson, AR, 1992) |
| "Although pentamidine isethionate is effective in the treatment of Pneumocystis carinii pneumonia, it frequently causes serious adverse reactions." | 5.27 | Recurrent ventricular tachycardia due to pentamidine-induced cardiotoxicity. ( Bibler, MR; Chou, TC; Toltzis, RJ; Wade, PA, 1988) |
| "To assess the safety and efficacy of aerosol pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS)." | 5.07 | Aerosol pentamidine for secondary prophylaxis of AIDS-related Pneumocystis carinii pneumonia. A randomized, placebo-controlled study. ( Chan, CK; Falutz, JM; Fong, IW; Gervais, A; Hyland, RH; Lawson, LM; MacFadden, D; Montaner, JS; Rachlis, AR; Renzi, PM, 1991) |
| "To compare inhaled pentamidine with intravenous pentamidine for the treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome (AIDS)." | 5.06 | Inhaled or intravenous pentamidine therapy for Pneumocystis carinii pneumonia in AIDS. A randomized trial. ( Meyer, RD; Mohsenifar, Z; Soo Hoo, GW, 1990) |
| "To evaluate the efficacy and toxicity of aerosolized pentamidine and of reduced-dose intravenous pentamidine for the treatment of mild to moderate Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS)." | 5.06 | Intravenous or inhaled pentamidine for treating Pneumocystis carinii pneumonia in AIDS. A randomized trial. ( Chernoff, D; Conte, JE; Feigal, DW; Golden, JA; Joseph, P; McDonald, C, 1990) |
| "To examine the efficacy and tolerance of pentamidine aerosol in the prevention of Pneumocystis carinii pneumonia (PCP) relapse in patients with the acquired immunodeficiency syndrome (AIDS) being treated with zidovudine, 51 patients who had had an episode of PCP in the previous 5 months were enrolled in a randomised controlled study." | 5.06 | Prevention of Pneumocystis carinii pneumonia relapse by pentamidine aerosol in zidovudine-treated AIDS patients. ( Camus, F; De Truchis, P; Farinotti, R; Gaudebout, C; Girard, PM; Landman, R; Lepretre, A; Lottin, P; Matheron, S; Michon, C, 1989) |
| "The aim of this study was to evaluate the outcome of pretreatment of Acanthamoeba keratitis with intravenous pentamidine (IVP) before therapeutic keratoplasty (TKP)." | 3.81 | Treatment of acanthamoeba keratitis with intravenous pentamidine before therapeutic keratoplasty. ( Goins, KM; Greiner, MA; Kitzmann, AS; Sacher, BA; Sutphin, JE; Wagoner, MD, 2015) |
| "Aerosolized pentamidine prophylaxis for Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS) may predispose these patients to recurrent apical Pneumocystis infection." | 3.68 | Spontaneous pneumothorax in AIDS patients with recurrent Pneumocystis carinii pneumonia despite aerosolized pentamidine prophylaxis. ( Haggerty, MF; Luyckx, BA; Murphy, TF; Shanley, DJ, 1991) |
| "Recurrent Pneumocystis carinii pneumonia is common in patients with the acquired immunodeficiency syndrome who receive prophylaxis with aerosolized pentamidine." | 3.68 | Diagnostic approach to Pneumocystis carinii pneumonia in the setting of prophylactic aerosolized pentamidine. ( Catanzaro, A; Metersky, ML, 1991) |
| "In order to determine the possible effect of aerosolized pentamidine on the cellular composition of the bronchoalveolar lavage fluid in HIV-infected patients, differential counts of 22 consecutive patients who had been rebronchoscopied after 3-19 months were reviewed." | 3.68 | Pentamidine aerosol increases the number of alveolar macrophages in HIV-infected patients. ( Don, M; Eckert, G; Hilger, HH; Pothoff, G; Schell-Frederick, E; Wassermann, K, 1991) |
| "Two cases of focal recurrent Pneumocystis carinii pneumonia (PCP) associated with pneumothorax occurred in patients with AIDS who had received aerosolized pentamidine therapy." | 3.68 | Pneumothoraces and Pneumocystis carinii pneumonia in two AIDS patients receiving aerosolized pentamidine. ( Scannell, KA, 1990) |
| "The efficacy and toxicity of pentamidine inhaled once a month to prevent Pneumocystis carinii pneumonia (PCP) was investigated in 102 patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC)." | 3.67 | Prevention of Pneumocystis carinii pneumonia by inhaled pentamidine. ( Chernoff, D; Conte, JE; Feigal, D; Golden, JA; Hollander, H, 1989) |
| "The main outcome assessments were PCP recurrence, survival and incidence of drug toxicity." | 2.68 | Better efficacy of twice-monthly than monthly aerosolised pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with AIDS. An Italian multicentric randomised controlled trial. The Italian PCP Study Group. ( Frigerio, D; Lazzarin, A; Lucchini, M; Maillard, M; Moroni, M; Musicco, M; Rizzardi, GP, 1995) |
| " Seven assigned to the 5-mg biweekly dosing schedule had a confirmed recurrence of PCP, compared with none in the 60-mg group (p = 0." | 2.67 | Aerosol pentamidine prophylaxis following Pneumocystis carinii pneumonia in AIDS patients: results of a blinded dose-comparison study using an ultrasonic nebulizer. ( Allan, JD; Boswell, SL; Davies, SF; Dupliss, R; Gordin, FM; Graziano, FM; Lavelle, JP; Murphy, RL; Saag, MS; Waskin, HA, 1991) |
| "The estimated recurrence rates at 18 months were 11." | 2.67 | A controlled trial of trimethoprim-sulfamethoxazole or aerosolized pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome. AIDS Clinical Trials Group Protocol 021. ( Fass, RJ; Feinberg, J; Finkelstein, DM; Frame, PT; Hardy, WD; He, W; Holmes, M; Kaczka, C; Power, ME; Waskin, H, 1992) |
| "Pentamidine was well tolerated and produced no severe side effects." | 2.67 | [Randomized comparative study of secondary prevention of Pneumocystis carinii pneumonia in patients with acquired immunologic deficiency syndrome]. ( Elsing, C; Franke, M; Höffken, G; Lode, H; Noack, H; Petri, M; Ruhnke, M; Schrappe-Bächer, M; Stellbrink, HJ; Weiss, R, 1990) |
| "Human African trypanosomiasis, or sleeping sickness, is a painful and protracted disease affecting people in the poorest parts of Africa and is fatal without treatment." | 2.49 | Chemotherapy for second-stage human African trypanosomiasis. ( Kennedy, A; Lutje, V; Seixas, J, 2013) |
| "Human African trypanosomiasis, or sleeping sickness, is a painful and protracted disease affecting people in the poorest parts of Africa and is fatal without treatment." | 2.46 | Chemotherapy for second-stage Human African trypanosomiasis. ( Kennedy, A; Lutje, V; Seixas, J, 2010) |
| "Human African trypanosomiasis (sleeping sickness) caused by Trypanosoma gambiense is recrudescing alarmingly in the Ivory Coast." | 2.38 | Human trypanosomiasis in the Ivory Coast: therapy and problems. ( Doua, F; Yapo, FB, 1993) |
| "A 43-year-old woman with AIDS experienced pentamidine-induced TdP." | 2.38 | Prolonged recurrence of pentamidine-induced torsades de pointes. ( Bjornson, DC; Cortese, LM; Dacey, MJ; Gasser, RA; Oster, CN, 1992) |
| "Pneumocystis carinii pneumonia is the most common life-threatening disease diagnosed in patients infected with the human immunodeficiency virus (HIV)." | 2.38 | Aerosolized pentamidine in HIV. Promising new treatment for Pneumocystis carinii pneumonia. ( Sarti, GM, 1989) |
| "Pentamidine mesylate was introduced by Niemel in 1973 for the treatment of cutaneous leishmaniasis in Surinam." | 1.31 | Pentamidine, the drug of choice for the treatment of cutaneous leishmaniasis in Surinam. ( Lai A Fat, EJ; Lai A Fat, RF; Soetosenojo, RM; Vrede, MA, 2002) |
| "Recurrence was observed in two patients who were retreated using the same agent." | 1.31 | [Epidemics of cutaneous leishmaniasis in military personnel working in French Guiana]. ( Banzet, S, 2000) |
| "We conclude that spontaneous pneumothorax is associated with poor prognosis in HIV infected patients." | 1.30 | [Spontaneous pneumothorax associated with human immunodeficiency virus (HIV) infection]. ( Cifrián Martínez, JM; Fernández Rozas, SM; García Pérez, MM; Golpe Gómez, R; Jiménez Gómez, A; Mons Lera, R, 1998) |
| "Frequent relapses after treatment for visceral leishmaniasis and apparent parasitological cure is not commonly reported." | 1.29 | Problems in the treatment of kala-azar: case report. ( Kirigi, G; Mbugua, J; Muigai, R; Nyakundi, PM; Rashid, JR; Wasunna, KM; Were, JB, 1995) |
| "Occurrence or recurrence of PCP." | 1.29 | Predictors for failure of Pneumocystis carinii pneumonia prophylaxis. Multicenter AIDS Cohort Study. ( Hoover, DR; Kingsley, LA; Peng, Y; Phair, JP; Saah, AJ; Schrager, LK; Visscher, B, 1995) |
| "A total of 25 cases of Pneumocystis carinii pneumonia was observed (3." | 1.29 | [Primary and secondary prevention of Pneumocystis carinii pneumonia with pentamidine aerosol. Effectiveness, side effects and incidence of extrapulmonary Pneumocystis carinii manifestations]. ( Albrecht, H; Begemann, F; Meigel, W; Plettenberg, A; Stellbrink, HJ; Stoehr, A, 1994) |
| "Extrapulmonary localizations of pneumocystosis were noticed (eye, liver, spleen, ascitis) in two AP+." | 1.29 | [Pneumocystis carinii pneumonia in AIDS: retrospective analysis of 80 documented cases (1985-1993)]. ( Aubertin, J; Bartou, C; Bernard, N; Beylot, J; Buisson, M; Couprie, B; Dequae, L; Lacoste, D; Mercié, P; Morlat, P; Ragnaud, JM, 1996) |
| "The WHO recommendations treating visceral leishmaniasis with prolonged administration of Glucantime may prevent relapses." | 1.29 | [Resistance of Leishmania infantum to Glucantime: risk factors and therapeutic management]. ( Dumon, H; Gambarelli, F; Garnier, JM; Kaplanski, S; Piarroux, R; Unal, D, 1996) |
| "However, nine of these relapsed with recurrence of respiratory failure after steroid therapy was withdrawn." | 1.28 | Steroids for Pneumocystis carinii pneumonia and respiratory failure in the acquired immunodeficiency syndrome. A reassessment. ( Farber, BF; Kaplan, MH; Schiff, MJ, 1990) |
| "His episodes of torsade de pointes were refractory to the usual therapy." | 1.28 | Torsade de pointes after inhaled pentamidine. ( Coodley, G; Engrav, MB; Magnusson, AR, 1992) |
| "We evaluated 43 AIDS patients on prophylaxis with aerosol pentamidine (60 mg biweekly) after Pneumocystis carinii pneumonia (PCP)." | 1.28 | Compliance and laboratory data predict relapse rate of Pneumocystis carinii pneumonia during prophylaxis with aerosol pentamidine. ( Ledergerber, B; Lüthy, R; Opravil, M; Siegenthaler, W; Speich, R; Weber, R, 1990) |
| "Pentamidine 60 mg was administered by ultrasonic nebulization (Fisoneb) five times during the first two weeks and then every two weeks." | 1.28 | Bilateral pneumothoraces hasten mortality in AIDS patients receiving secondary prophylaxis with aerosolized pentamidine. Association with a lower Dco prior to receiving aerosolized pentamidine. ( Braidy, J; Chassé, M; Corbeil, C; Matar, N; Renzi, PM, 1992) |
| "A patient with a history of Pneumocystis carinii pneumonia (PCP) inhaled aerosolized pentamidine (AP) for secondary prophylaxis of PCP." | 1.28 | Upper lobe relapse of Pneumocystis carinii pneumonia during aerosolized pentamidine prophylaxis. ( Grünewald, T; Jautzke, G; Köppen, S; Ruf, B, 1991) |
| "In 33 consecutive AIDS patients with a first episode of Pneumocystis carinii pneumonia (PCP) we evaluated treatment, outcome, recurrence rate and pyrimethamine as chemoprophylaxis in a 1-year follow-up." | 1.28 | Pneumocystis carinii pneumonia in Stockholm, Sweden: treatment, outcome, one-year-follow-up and pyrimethamine prophylaxis. ( Bergdahl, S; Julander, I; Lidman, C; Lundbergh, P; Ortqvist, A, 1989) |
| "Only one (1." | 1.28 | Trimethoprim-sulphamethoxazole appears more effective than aerosolized pentamidine as secondary prophylaxis against Pneumocystis carinii pneumonia in patients with AIDS. ( Carr, A; Cooper, DA; Penny, R; Tindall, B, 1992) |
| "Pneumocystis carinii pneumonia was diagnosed by bronchoalveolar lavage of the upper lobes in a patient with the acquired immunodeficiency syndrome (AIDS) receiving aerosol pentamidine prophylaxis." | 1.28 | Relapse of Pneumocystis carinii pneumonia in the upper lobes during aerosol pentamidine prophylaxis. ( Bradburne, RM; Ettensohn, DB; McCool, FD; Opal, SM, 1989) |
| "Eight episodes were proven Pneumocystis carinii pneumonia, 18 satisfied Centres for Disease Control criteria for presumptive Pneumocystis carinii pneumonia and 11 lacked one Centres for Disease Control criterion." | 1.28 | Experience with pneumocystis carinii pneumonia in patients with AIDS. ( Davis, R; Ellis-Pegler, RB; Ingram, RJ, 1989) |
| "The prevention of the occurrence and recurrence of PCP is a cornerstone in the treatment of patients infected with the human immunodeficiency virus." | 1.28 | A comparison of the effectiveness of three regimens in the prevention of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected patients. ( Beall, GN; Beck, K; Cox, PH; Martin, MA; Styer, CM, 1992) |
| "Although pentamidine isethionate is effective in the treatment of Pneumocystis carinii pneumonia, it frequently causes serious adverse reactions." | 1.27 | Recurrent ventricular tachycardia due to pentamidine-induced cardiotoxicity. ( Bibler, MR; Chou, TC; Toltzis, RJ; Wade, PA, 1988) |
| "Patients with the acquired immunodeficiency syndrome who have PCP have a high trimethoprim-sulfamethoxazole failure rate, due either to adverse reactions or unresponsive infection." | 1.27 | The treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. ( Friedland, GH; Harris, CA; Klein, RS; Small, CB, 1985) |
| "Since recurrence of PCP is common, follow-up lung biopsy (15 transbronchial, one open) was performed as part of the clinical evaluation of 16 episodes of PCP." | 1.27 | Persistence of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. Evaluation of therapy by follow-up transbronchial lung biopsy. ( Davidian, MM; DeLorenzo, LJ; Maguire, GP; Stone, DJ; Wormser, GP, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (27.88) | 18.7374 |
| 1990's | 53 (50.96) | 18.2507 |
| 2000's | 10 (9.62) | 29.6817 |
| 2010's | 10 (9.62) | 24.3611 |
| 2020's | 2 (1.92) | 2.80 |
| Authors | Studies |
|---|---|
| Chechi, F | 1 |
| Corsi, P | 1 |
| Bartolozzi, D | 1 |
| Gaiera, G | 2 |
| Bartoloni, A | 2 |
| Zammarchi, L | 2 |
| Basile, G | 1 |
| Cristofaro, G | 1 |
| Locatello, LG | 1 |
| Vellere, I | 1 |
| Piccica, M | 1 |
| Bresci, S | 1 |
| Maggiore, G | 1 |
| Gallo, O | 1 |
| Novelli, A | 1 |
| Di Muccio, T | 1 |
| Gramiccia, M | 1 |
| Gradoni, L | 1 |
| Diro, E | 2 |
| Ritmeijer, K | 2 |
| Boelaert, M | 2 |
| Alves, F | 2 |
| Mohammed, R | 2 |
| Abongomera, C | 2 |
| Ravinetto, R | 2 |
| De Crop, M | 2 |
| Fikre, H | 2 |
| Adera, C | 2 |
| van Loen, H | 2 |
| Tsoumanis, A | 1 |
| Adriaensen, W | 1 |
| Hailu, A | 2 |
| Griensven, JV | 1 |
| Lutje, V | 2 |
| Seixas, J | 2 |
| Kennedy, A | 2 |
| Gomes, CM | 1 |
| Cesetti, MV | 1 |
| de Morais, OO | 1 |
| Mendes, MS | 1 |
| Roselino, AM | 1 |
| Sampaio, RN | 1 |
| Sacher, BA | 1 |
| Wagoner, MD | 1 |
| Goins, KM | 1 |
| Sutphin, JE | 1 |
| Greiner, MA | 1 |
| Kitzmann, AS | 1 |
| Pyana Pati, P | 1 |
| Van Reet, N | 1 |
| Mumba Ngoyi, D | 1 |
| Ngay Lukusa, I | 1 |
| Karhemere Bin Shamamba, S | 1 |
| Büscher, P | 2 |
| Bourreau, E | 1 |
| Ginouves, M | 1 |
| Prévot, G | 1 |
| Hartley, MA | 1 |
| Gangneux, JP | 2 |
| Robert-Gangneux, F | 1 |
| Dufour, J | 1 |
| Sainte-Marie, D | 2 |
| Bertolotti, A | 1 |
| Pratlong, F | 2 |
| Martin, R | 1 |
| Schütz, F | 1 |
| Couppié, P | 2 |
| Fasel, N | 1 |
| Ronet, C | 1 |
| Colebunders, R | 1 |
| Menten, J | 1 |
| Lynen, L | 1 |
| van Griensven, J | 1 |
| Deschamps, JY | 1 |
| Desquesnes, M | 1 |
| Dorso, L | 1 |
| Ravel, S | 1 |
| Bossard, G | 1 |
| Charbonneau, M | 1 |
| Garand, A | 1 |
| Roux, FA | 1 |
| García-Lázaro, M | 1 |
| Villar, C | 1 |
| Natera, C | 1 |
| Rivero, A | 1 |
| Truc, P | 1 |
| Lando, A | 1 |
| Penchenier, L | 1 |
| Vatunga, G | 1 |
| Josenando, T | 1 |
| Lai A Fat, EJ | 1 |
| Vrede, MA | 1 |
| Soetosenojo, RM | 1 |
| Lai A Fat, RF | 1 |
| Lejon, V | 1 |
| Legros, D | 1 |
| Savignoni, A | 1 |
| Etchegorry, MG | 1 |
| Mbulamberi, D | 1 |
| Clyti, E | 1 |
| Sobesky, M | 1 |
| Bissuel, F | 1 |
| Del Giudice, P | 1 |
| Dedet, JP | 1 |
| Carme, B | 1 |
| Pradinaud, R | 1 |
| Anene, BM | 1 |
| Ezeokonkwo, RC | 1 |
| Mmesirionye, TI | 1 |
| Tettey, JN | 1 |
| Brock, JM | 1 |
| Barrett, MP | 1 |
| De Koning, HP | 1 |
| Simarro, PP | 1 |
| Franco, JR | 1 |
| Ndongo, P | 1 |
| Nguema, E | 1 |
| Louis, FJ | 1 |
| Jannin, J | 1 |
| Balasegaram, M | 1 |
| Harris, S | 1 |
| Checchi, F | 1 |
| Hamel, C | 1 |
| Karunakara, U | 1 |
| López-Medrano, F | 1 |
| Costa, JR | 1 |
| Rodriguez-Peralto, JL | 1 |
| Aguado, JM | 1 |
| Sauzet, S | 1 |
| Donnard, S | 1 |
| Meyer, N | 1 |
| Cornillet, A | 1 |
| Guiguen, C | 1 |
| Hughes, WT | 3 |
| Wittermann, C | 1 |
| Reindke, B | 1 |
| Bienzle, U | 1 |
| Doua, F | 3 |
| Boa Yapo, F | 2 |
| Nyakundi, PM | 1 |
| Rashid, JR | 1 |
| Wasunna, KM | 1 |
| Were, JB | 1 |
| Muigai, R | 1 |
| Kirigi, G | 1 |
| Mbugua, J | 1 |
| Hoernle, EH | 1 |
| Reid, TE | 1 |
| Saah, AJ | 1 |
| Hoover, DR | 1 |
| Peng, Y | 1 |
| Phair, JP | 1 |
| Visscher, B | 1 |
| Kingsley, LA | 1 |
| Schrager, LK | 1 |
| Yapo, FB | 1 |
| Stoehr, A | 1 |
| Plettenberg, A | 1 |
| Albrecht, H | 1 |
| Stellbrink, HJ | 2 |
| Meigel, W | 1 |
| Begemann, F | 1 |
| Albort, JV | 1 |
| Callejas, MA | 1 |
| Canalis, EA | 1 |
| Catalán, M | 1 |
| Sanchez-Lloret, J | 1 |
| Nielsen, TL | 2 |
| Jensen, BN | 2 |
| Nelsing, S | 1 |
| Mathiesen, LR | 1 |
| Skinhøj, P | 2 |
| Nielsen, JO | 2 |
| Rizzardi, GP | 1 |
| Lazzarin, A | 1 |
| Musicco, M | 1 |
| Frigerio, D | 1 |
| Maillard, M | 1 |
| Lucchini, M | 1 |
| Moroni, M | 1 |
| Morlat, P | 1 |
| Bartou, C | 1 |
| Ragnaud, JM | 1 |
| Dequae, L | 1 |
| Lacoste, D | 1 |
| Buisson, M | 1 |
| Bernard, N | 1 |
| Mercié, P | 1 |
| Couprie, B | 1 |
| Beylot, J | 1 |
| Aubertin, J | 1 |
| Piarroux, R | 1 |
| Garnier, JM | 1 |
| Gambarelli, F | 1 |
| Dumon, H | 1 |
| Kaplanski, S | 1 |
| Unal, D | 1 |
| Miezan, TW | 1 |
| Sanon Singaro, JR | 1 |
| Baltz, T | 1 |
| Larriviere-Chouc, C | 1 |
| De Pina, JJ | 1 |
| Faraut-Gambarelli, F | 1 |
| Morillon, M | 1 |
| Normand, P | 1 |
| Pérez-Molina, JA | 1 |
| Guerrero, A | 1 |
| Dumas, M | 1 |
| Bouteille, B | 1 |
| Golpe Gómez, R | 1 |
| Cifrián Martínez, JM | 1 |
| Fernández Rozas, SM | 1 |
| García Pérez, MM | 1 |
| Mons Lera, R | 1 |
| Jiménez Gómez, A | 1 |
| Bossi, P | 1 |
| Caumes, E | 1 |
| Astagneau, P | 1 |
| Li, TS | 1 |
| Paris, L | 1 |
| Mengual, X | 1 |
| Katlama, C | 1 |
| Bricaire, F | 1 |
| Herrmann, BL | 1 |
| Saller, B | 1 |
| Sauer, J | 1 |
| Brockmeyer, N | 1 |
| Mann, K | 1 |
| Gray, JS | 1 |
| Pudney, M | 1 |
| Banzet, S | 1 |
| Miller, LH | 1 |
| Neva, FA | 1 |
| Gill, F | 1 |
| Engrav, MB | 1 |
| Coodley, G | 1 |
| Magnusson, AR | 1 |
| Hardy, WD | 1 |
| Feinberg, J | 1 |
| Finkelstein, DM | 1 |
| Power, ME | 1 |
| He, W | 1 |
| Kaczka, C | 1 |
| Frame, PT | 1 |
| Holmes, M | 1 |
| Waskin, H | 1 |
| Fass, RJ | 1 |
| Cortese, LM | 1 |
| Gasser, RA | 1 |
| Bjornson, DC | 1 |
| Dacey, MJ | 1 |
| Oster, CN | 1 |
| Martin, MA | 1 |
| Cox, PH | 1 |
| Beck, K | 1 |
| Styer, CM | 1 |
| Beall, GN | 1 |
| Carr, A | 1 |
| Tindall, B | 1 |
| Penny, R | 1 |
| Cooper, DA | 1 |
| Renzi, PM | 2 |
| Corbeil, C | 1 |
| Chassé, M | 1 |
| Braidy, J | 1 |
| Matar, N | 1 |
| Thakur, CP | 2 |
| Kumar, M | 2 |
| Pandey, AK | 2 |
| Castellano, AR | 1 |
| Nettleman, MD | 1 |
| Wassermann, K | 1 |
| Schell-Frederick, E | 1 |
| Eckert, G | 1 |
| Don, M | 1 |
| Pothoff, G | 1 |
| Hilger, HH | 1 |
| McCabe, R | 1 |
| Metersky, ML | 1 |
| Catanzaro, A | 1 |
| Köppen, S | 1 |
| Grünewald, T | 1 |
| Jautzke, G | 1 |
| Ruf, B | 1 |
| Foster, RE | 1 |
| Lowder, CY | 1 |
| Meisler, DM | 1 |
| Huang, SS | 1 |
| Longworth, DL | 1 |
| Smith, DE | 1 |
| Hills, DA | 1 |
| Harman, C | 1 |
| Hawkins, DA | 1 |
| Gazzard, BG | 1 |
| Shanley, DJ | 1 |
| Luyckx, BA | 1 |
| Haggerty, MF | 1 |
| Murphy, TF | 1 |
| Camus, F | 2 |
| de Picciotto, C | 1 |
| Leprêtre, A | 2 |
| Landman, R | 2 |
| Girard, PM | 2 |
| Murphy, RL | 1 |
| Lavelle, JP | 1 |
| Allan, JD | 1 |
| Gordin, FM | 1 |
| Dupliss, R | 1 |
| Boswell, SL | 1 |
| Waskin, HA | 1 |
| Davies, SF | 1 |
| Graziano, FM | 1 |
| Saag, MS | 1 |
| Montaner, JS | 1 |
| Lawson, LM | 1 |
| Gervais, A | 1 |
| Hyland, RH | 1 |
| Chan, CK | 1 |
| Falutz, JM | 1 |
| MacFadden, D | 1 |
| Rachlis, AR | 1 |
| Fong, IW | 1 |
| Miller, R | 1 |
| Steel, S | 1 |
| Fortún, J | 1 |
| Antela, A | 1 |
| Rey, J | 1 |
| Montilla, P | 1 |
| Höffken, G | 1 |
| Elsing, C | 1 |
| Ruhnke, M | 1 |
| Franke, M | 1 |
| Schrappe-Bächer, M | 1 |
| Weiss, R | 1 |
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| Soo Hoo, GW | 1 |
| Mohsenifar, Z | 1 |
| Meyer, RD | 1 |
| Conte, JE | 2 |
| Chernoff, D | 2 |
| Feigal, DW | 1 |
| Joseph, P | 1 |
| McDonald, C | 1 |
| Golden, JA | 2 |
| Schiff, MJ | 1 |
| Farber, BF | 1 |
| Kaplan, MH | 1 |
| Amin, MB | 1 |
| Abrash, MP | 1 |
| Mezger, E | 1 |
| Sekerak, GF | 1 |
| Edelstein, H | 1 |
| McCabe, RE | 1 |
| Lerche, B | 1 |
| Jensen, TH | 1 |
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| Scannell, KA | 2 |
| Green, ST | 1 |
| Nathwani, D | 1 |
| Christie, PR | 1 |
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| Stover, DE | 1 |
| Zaman, MB | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Secondary Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients Using Pentamidine as a Prophylactic Agent: a Prospective Cohort Study[NCT01360762] | Phase 3 | 74 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| A Controlled Comparative Trial of Trimethoprim - Sulfamethoxazole Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT)[NCT00000727] | Phase 3 | 322 participants | Interventional | Completed | |||
| Phase 3 Open-label Study of Efficacy and Safety of Miltefosine or Thermotherapy vs Glucantime for Cutaneous Leishmaniasis in Colombia.[NCT00471705] | Phase 3 | 437 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| A Double-Blind Group Comparative Study To Evaluate the Long-Term Safety and Effectiveness of Two Different Doses of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients With Multiple Episodes of PCP[NCT00002055] | 0 participants | Interventional | Completed | ||||
| A Double-Blind Group Comparative Study To Evaluate the Safety and Effectiveness of Three Different Doses of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in Patients With AIDS Post First Episode PCP[NCT00002291] | 0 participants | Interventional | Completed | ||||
| Inhaled Versus Intravenous Pentamidine in Pneumocystis Carinii Pneumonia in the Acquired Immunodeficiency Syndrome[NCT00002292] | 0 participants | Interventional | Completed | ||||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of patients with SAEs which are possibly, probably or definitely drug-related following clinician's assessment or that lead to permanent drug discontinuations during the first year of pentamidine administration (NCT01360762)
Timeframe: 1 year
| Intervention | Participants (Count of Participants) |
|---|---|
| Pentamidine Secondary Prophylaxis (PSP) | 3 |
During the first year of pentamidine administration for prophylaxis: participants with any drug-related non-serious adverse events (with drug-related defined as possibly, probably or definitely related to primary therapy following physicians assessment) as well as any serious adverse events (drug-related or not) (NCT01360762)
Timeframe: 1 year
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Drug-related non-serious adverse events | Any serious adverse event | |
| Pentamidine Secondary Prophylaxis (PSP) | 30 | 17 |
The number of required additional clinical interventions/therapeutic procedures (NCT01360762)
Timeframe: 30 months
| Intervention | number of events (Number) | |||
|---|---|---|---|---|
| Additional IV fluid during PM administration | Prolonged hospital observation | additional medication during PM infusion | Additional IV or oral glucose | |
| Pentamidine Secondary Prophylaxis (PSP) | 10 | 2 | 2 | 1 |
Number of treatment discontinuations and interruptions/missed doses. (NCT01360762)
Timeframe: 30 months
| Intervention | number of events (Number) | ||
|---|---|---|---|
| Permanent discontinuation | Missed more than 1 dose | Treatment interruption | |
| Pentamidine Secondary Prophylaxis (PSP) | 2 | 4 | 0 |
Probability of relapse-free survival up to one year after the start of the intervention (PSP) (at month 6 and month 12) (NCT01360762)
Timeframe: up to 1 year after the start of the intervention (PSP)
| Intervention | percentage probability (Number) | |
|---|---|---|
| Probability of relapse-free survival at 6 months | Probability of relapse-free survival at 12 months | |
| Pentamidine Secondary Prophylaxis (PSP) | 79 | 71 |
"Complete Clinical response: Initial cure plus the absence of recurrences or mucosal lesions for 6 months after the end of treatment.~Note: nitial cure: Complete re-epithelialization of all ulcers and complete disappearance of the induration up to 3 months after the end of treatment." (NCT00471705)
Timeframe: Until 6 months posttreatment
| Intervention | participants (Number) |
|---|---|
| Miltefosine | 85 |
| Glucantime® | 103 |
| Thermotherapy | 86 |
At least 50% increase in lesion size at the end of treatment, absence of clinical response at 6 weeks, or any sign of lesion activity 3 months after the end of treatment (NCT00471705)
Timeframe: Until 3 months posttreatment
| Intervention | participants (Number) |
|---|---|
| Miltefosine | 34 |
| Glucantime® | 14 |
| Thermotherapy | 42 |
Reactivation of the lesion at the original site after cure or mucosal compromise during follow-up. (NCT00471705)
Timeframe: Until 6 months post-treatment
| Intervention | Participants (Number) |
|---|---|
| Miltefosine | 3 |
| Glucantime® | 4 |
| Thermotherapy | 6 |
12 reviews available for pentamidine and Recrudescence
| Article | Year |
|---|---|
Chemotherapy for second-stage human African trypanosomiasis.
Topics: Animals; Antiprotozoal Agents; Drug Therapy, Combination; Eflornithine; Humans; Melarsoprol; Nifurti | 2013 |
Chemotherapy for second-stage Human African trypanosomiasis.
Topics: Animals; Antiprotozoal Agents; Drug Therapy, Combination; Eflornithine; Humans; Melarsoprol; Nifurti | 2010 |
Pneumocystis carinii pneumonitis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antibodies; Child; Drug Combinations; Humans; Immunologic | 1984 |
Human immunodeficiency virus infection in children.
Topics: Adolescent; AIDS-Related Opportunistic Infections; Child; Child, Preschool; Dapsone; Didanosine; Dru | 1995 |
Human trypanosomiasis in the Ivory Coast: therapy and problems.
Topics: Animals; Cote d'Ivoire; Eflornithine; Humans; Melarsoprol; Pentamidine; Recurrence; Trypanosoma bruc | 1993 |
Prolonged recurrence of pentamidine-induced torsades de pointes.
Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Humans; Infusions, Intravenous; Pentamidine; Pneu | 1992 |
Nebulized pentamidine for the prevention of Pneumocystis carinii pneumonia in AIDS patients: experience of 173 patients and a review of the literature.
Topics: Acquired Immunodeficiency Syndrome; Drug Administration Schedule; Humans; Male; Nebulizers and Vapor | 1991 |
Nebulized pentamidine as prophylaxis for Pneumocystis carinii pneumonia.
Topics: Humans; Nebulizers and Vaporizers; Pentamidine; Pneumonia, Pneumocystis; Recurrence; Trimethoprim, S | 1991 |
Aerosolized pentamidine in HIV. Promising new treatment for Pneumocystis carinii pneumonia.
Topics: Aerosols; Amidines; Animals; Anti-Infective Agents; Child; Drug Combinations; Female; HIV Seropositi | 1989 |
Prophylaxis of Pneumocystis carinii pneumonia in patients infected with the human immunodeficiency virus type 1.
Topics: Acquired Immunodeficiency Syndrome; Drug Combinations; Humans; Nebulizers and Vaporizers; Pentamidin | 1989 |
Pneumocystis carinii pneumonia: therapy and prophylaxis.
Topics: Acquired Immunodeficiency Syndrome; Anti-Bacterial Agents; Dapsone; Drug Combinations; Drug Therapy, | 1988 |
Prevention of Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Aerosols; Dapsone; Drug Combinations; Humans; Pentamidine; Pneum | 1988 |
14 trials available for pentamidine and Recrudescence
| Article | Year |
|---|---|
Long-term Clinical Outcomes in Visceral Leishmaniasis/Human Immunodeficiency Virus-Coinfected Patients During and After Pentamidine Secondary Prophylaxis in Ethiopia: A Single-Arm Clinical Trial.
Topics: Adult; Antiprotozoal Agents; Coinfection; Ethiopia; Female; HIV Infections; Humans; Leishmaniasis, V | 2018 |
Neuro-inflammatory risk factors for treatment failure in "early second stage" sleeping sickness patients treated with pentamidine.
Topics: Adolescent; Adult; Animals; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Female; Humans; I | 2003 |
Randomized study of sulfamethoxazole-trimethoprim versus aerosolized pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with AIDS.
Topics: Administration, Inhalation; Administration, Oral; Adult; Aerosols; Aged; AIDS-Related Opportunistic | 1995 |
Better efficacy of twice-monthly than monthly aerosolised pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with AIDS. An Italian multicentric randomised controlled trial. The Italian PCP Study Group.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Aerosols; Antifungal Agents; | 1995 |
A controlled trial of trimethoprim-sulfamethoxazole or aerosolized pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome. AIDS Clinical Trials Group Protocol 021.
Topics: Aerosols; AIDS-Related Opportunistic Infections; Female; Follow-Up Studies; Humans; Male; Pentamidin | 1992 |
Evaluation of efficacy of longer durations of therapy of fresh cases of kala-azar with sodium stibogluconate.
Topics: Adult; Antimony Sodium Gluconate; Child; Female; Follow-Up Studies; Humans; Leishmaniasis, Visceral; | 1991 |
Comparison of regimes of treatment of antimony-resistant kala-azar patients: a randomized study.
Topics: Adolescent; Adult; Antimony Sodium Gluconate; Child; Child, Preschool; Drug Administration Schedule; | 1991 |
Aerosol pentamidine prophylaxis following Pneumocystis carinii pneumonia in AIDS patients: results of a blinded dose-comparison study using an ultrasonic nebulizer.
Topics: Adult; Aerosols; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; HIV Inf | 1991 |
Aerosol pentamidine prophylaxis following Pneumocystis carinii pneumonia in AIDS patients: results of a blinded dose-comparison study using an ultrasonic nebulizer.
Topics: Adult; Aerosols; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; HIV Inf | 1991 |
Aerosol pentamidine prophylaxis following Pneumocystis carinii pneumonia in AIDS patients: results of a blinded dose-comparison study using an ultrasonic nebulizer.
Topics: Adult; Aerosols; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; HIV Inf | 1991 |
Aerosol pentamidine prophylaxis following Pneumocystis carinii pneumonia in AIDS patients: results of a blinded dose-comparison study using an ultrasonic nebulizer.
Topics: Adult; Aerosols; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; HIV Inf | 1991 |
Aerosol pentamidine for secondary prophylaxis of AIDS-related Pneumocystis carinii pneumonia. A randomized, placebo-controlled study.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Bronchial Spasm; Cough; Female; Follow-Up Studi | 1991 |
[Randomized comparative study of secondary prevention of Pneumocystis carinii pneumonia in patients with acquired immunologic deficiency syndrome].
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Female; HIV Seropositivity; H | 1990 |
Inhaled or intravenous pentamidine therapy for Pneumocystis carinii pneumonia in AIDS. A randomized trial.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Drug Administration Schedule; | 1990 |
Intravenous or inhaled pentamidine for treating Pneumocystis carinii pneumonia in AIDS. A randomized trial.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Female; Humans; Infusions, In | 1990 |
Prevention of Pneumocystis carinii pneumonia relapse by pentamidine aerosol in zidovudine-treated AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Aerosols; Amidines; Analysis | 1989 |
Pentamidine aerosol to prevent Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Aerosols; Amidines; CD4-Positive T-Lymphocytes; Clinical Trials | 1989 |
78 other studies available for pentamidine and Recrudescence
| Article | Year |
|---|---|
Case Report: Intravenous Pentamidine Rescue Treatment for Active Chronic Visceral Leishmaniasis in an HIV-1 Infected Patient.
Topics: Administration, Intravenous; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Coinfectio | 2021 |
Refractory mucocutaneous leishmaniasis resolved with combination treatment based on intravenous pentamidine, oral azole, aerosolized liposomal amphotericin B, and intralesional meglumine antimoniate.
Topics: Administration, Intravenous; Aged; Amphotericin B; Antiprotozoal Agents; Argentina; Azoles; Drug The | 2020 |
The influence of treatment on the development of leishmaniasis recidiva cutis: a 17-year case-control study in Midwestern Brazil.
Topics: Adolescent; Adult; Amphotericin B; Brazil; Case-Control Studies; Female; Humans; Incidence; Leishman | 2015 |
Treatment of acanthamoeba keratitis with intravenous pentamidine before therapeutic keratoplasty.
Topics: Acanthamoeba Keratitis; Adolescent; Adult; Antiprotozoal Agents; Female; Graft Survival; Humans; Inf | 2015 |
Melarsoprol sensitivity profile of Trypanosoma brucei gambiense isolates from cured and relapsed sleeping sickness patients from the Democratic Republic of the Congo.
Topics: Adult; Animals; Aquaglyceroporins; Base Sequence; Democratic Republic of the Congo; DNA, Protozoan; | 2014 |
Presence of Leishmania RNA Virus 1 in Leishmania guyanensis Increases the Risk of First-Line Treatment Failure and Symptomatic Relapse.
Topics: Adult; Antiprotozoal Agents; Cohort Studies; Female; Humans; Leishmania guyanensis; Leishmaniasis, M | 2016 |
Use of Pentamidine As Secondary Prophylaxis to Prevent Visceral Leishmaniasis Relapse in HIV Infected Patients, the First Twelve Months of a Prospective Cohort Study.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Cohort Studies; Female; Humans; | 2015 |
Refractory hypoglycaemia in a dog infected with Trypanosoma congolense.
Topics: Africa South of the Sahara; Animals; Antiprotozoal Agents; Dog Diseases; Dogs; Female; Fever; Glucos | 2016 |
[Raised tattoos in a human-immunodeficiency-virus-infected patient].
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiprotozoal Agents; Antiretroviral | 2009 |
Human African trypanosomiasis in Angola: clinical observations, treatment, and use of PCR for stage determination of early stage of the disease.
Topics: Adult; Angola; Animals; Eflornithine; Female; Follow-Up Studies; Humans; Lymphocyte Count; Male; Nuc | 2012 |
Pentamidine, the drug of choice for the treatment of cutaneous leishmaniasis in Surinam.
Topics: Adolescent; Adult; Aged; Antiprotozoal Agents; Child; Child, Preschool; Drug Administration Schedule | 2002 |
Comparative study of cutaneous leishmaniasis in human immunodeficiency virus (HIV)-infected patients and non-HIV-infected patients in French Guiana.
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Case-Control Studies; CD4 | 2004 |
A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats.
Topics: Animals; Diminazene; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Resistance | 2006 |
The elimination of Trypanosoma brucei gambiense sleeping sickness in the focus of Luba, Bioko Island, Equatorial Guinea.
Topics: Agglutination Tests; Animals; Disease Outbreaks; Disease Vectors; Endemic Diseases; Equatorial Guine | 2006 |
Treatment outcomes and risk factors for relapse in patients with early-stage human African trypanosomiasis (HAT) in the Republic of the Congo.
Topics: Adolescent; Adult; Animals; Child; Cohort Studies; Democratic Republic of the Congo; Disease Progres | 2006 |
An HIV-positive man with tattoo induration.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Animals; Antiprotozoal Agents; Biopsy, Needle | 2007 |
Recurrent American cutaneous leishmaniasis.
Topics: Antiprotozoal Agents; Humans; Leishmaniasis, Cutaneous; Military Personnel; Pentamidine; Recurrence | 2007 |
[Diagnosis and therapy of visceral leishmaniasis].
Topics: Antimony; Child, Preschool; Humans; Leishmaniasis, Visceral; Pentamidine; Recurrence | 1980 |
[Current therapy of trypanosomiasis].
Topics: Adenosylmethionine Decarboxylase; Animals; Arsenicals; Deoxyadenosines; Drug Resistance; Eflornithin | 1994 |
Problems in the treatment of kala-azar: case report.
Topics: Allopurinol; Animals; Antimetabolites; Antimony Sodium Gluconate; Antiprotozoal Agents; Child; Human | 1995 |
Predictors for failure of Pneumocystis carinii pneumonia prophylaxis. Multicenter AIDS Cohort Study.
Topics: Adult; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Dapsone; HIV Infections; HIV-1; | 1995 |
[Primary and secondary prevention of Pneumocystis carinii pneumonia with pentamidine aerosol. Effectiveness, side effects and incidence of extrapulmonary Pneumocystis carinii manifestations].
Topics: Administration, Inhalation; Adult; Aerosols; AIDS-Related Opportunistic Infections; Female; Follow-U | 1994 |
Surgical management of spontaneous pneumothorax in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Humans; Pentamidine; Pneumothorax; Recurrence | 1993 |
[Pneumocystis carinii pneumonia in AIDS: retrospective analysis of 80 documented cases (1985-1993)].
Topics: Adult; Aerosols; Aged; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Agen | 1996 |
[Resistance of Leishmania infantum to Glucantime: risk factors and therapeutic management].
Topics: Animals; Antiprotozoal Agents; Drug Resistance; Female; Humans; Immunity, Cellular; Infant; Interfer | 1996 |
The efficacy of pentamidine in the treatment of early-late stage Trypanosoma brucei gambiense trypanosomiasis.
Topics: Adolescent; Adult; Aged; Animals; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Child; Child, P | 1996 |
[Identification of Leishmania (V) guyanensis during recurrences of cutaneous leishmaniasis contracted in French Guyana].
Topics: Animals; Antiprotozoal Agents; French Guiana; Humans; Leishmania guyanensis; Leishmaniasis, Cutaneou | 1996 |
Secondary prophylaxis for visceral leishmaniasis in HIV-infected individuals.
Topics: AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Humans; Leishmaniasis, Visceral; Pentam | 1997 |
[Current status of trypanosomiasis].
Topics: Africa; Animals; Autoantibodies; Blood-Brain Barrier; Brain Diseases; Follow-Up Studies; Forecasting | 1997 |
[Spontaneous pneumothorax associated with human immunodeficiency virus (HIV) infection].
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Drainage; Female; HIV Infection | 1998 |
[Epidemiologic characteristics of cerebral toxoplasmosis in 399 HIV-infected patients followed between 1983 and 1994].
Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Anti-Infective Agents; Antibodies, Protozoan; | 1998 |
[26-year-old patient with cutaneous leishmaniasis and an initial diabetes mellitus manifestation].
Topics: Adult; Antiprotozoal Agents; Diabetes Mellitus, Type 1; Drug Administration Schedule; Female; Follow | 1999 |
Activity of atovaquone against Babesia microti in the Mongolian gerbil, Meriones unguiculatus.
Topics: Acute Disease; Animals; Antiprotozoal Agents; Atovaquone; Babesiosis; Chronic Disease; Clindamycin; | 1999 |
[Epidemics of cutaneous leishmaniasis in military personnel working in French Guiana].
Topics: Antiprotozoal Agents; Bedding and Linens; Clothing; French Guiana; Humans; Insect Repellents; Insect | 2000 |
Failure of chloroquine in human babesiosis (Babesia microti): case report and chemotherapeutic trials in hamsters.
Topics: Animals; Babesiosis; Benzamidines; Chloroquine; Cricetinae; Drug Resistance; Humans; Male; Metronida | 1978 |
Torsade de pointes after inhaled pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Combined Modality Therapy; El | 1992 |
A comparison of the effectiveness of three regimens in the prevention of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Dapsone; Drug Administration Schedule; Drug Therapy | 1992 |
Trimethoprim-sulphamethoxazole appears more effective than aerosolized pentamidine as secondary prophylaxis against Pneumocystis carinii pneumonia in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Aged; Follow-Up Studies; Huma | 1992 |
Bilateral pneumothoraces hasten mortality in AIDS patients receiving secondary prophylaxis with aerosolized pentamidine. Association with a lower Dco prior to receiving aerosolized pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Female; Humans; Lung Volume Measurements; Male; | 1992 |
Cost and benefit of secondary prophylaxis for Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Aerosols; Clinical Protocols; Cost-Benefit | 1991 |
Pentamidine aerosol increases the number of alveolar macrophages in HIV-infected patients.
Topics: Administration, Inhalation; Adult; Aerosols; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cell Count; | 1991 |
Aerosolized pentamidine prophylaxis.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Follow-Up Studies; Humans; Pentamidi | 1991 |
Diagnostic approach to Pneumocystis carinii pneumonia in the setting of prophylactic aerosolized pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Humans; Length of Stay; Male; | 1991 |
Upper lobe relapse of Pneumocystis carinii pneumonia during aerosolized pentamidine prophylaxis.
Topics: Adult; Aerosols; HIV Infections; Humans; Male; Opportunistic Infections; Pentamidine; Pneumonia, Pne | 1991 |
Presumed Pneumocystis carinii choroiditis. Unifocal presentation, regression with intravenous pentamidine, and choroiditis recurrence.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Choroiditis; Eye Infections, | 1991 |
Spontaneous pneumothorax in AIDS patients with recurrent Pneumocystis carinii pneumonia despite aerosolized pentamidine prophylaxis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Humans; Lung; Male; Middle Aged; Pentamidine; P | 1991 |
Pulmonary tolerance of prophylactic aerosolized pentamidine in human immunodeficiency virus-infected patients.
Topics: Aerosols; Cohort Studies; Drug Tolerance; Forced Expiratory Volume; HIV Infections; Humans; Lung; Ox | 1991 |
[Pneumocystis carinii recurrence after the use of prophylactic inhaled pentamidine. The unusual radiological findings].
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Heroin Dependence; Humans; Lu | 1991 |
The prevention of P. carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Adult; Biopsy; Bronchoscopy; Diagnosis, Differential; HIV Antibo | 1990 |
Steroids for Pneumocystis carinii pneumonia and respiratory failure in the acquired immunodeficiency syndrome. A reassessment.
Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; Female; Humans; Male; Methylprednisol | 1990 |
Systemic dissemination of Pneumocystis carinii in a patient with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Humans; Liver; Lung; Male; Pentamidine; Pneumon | 1990 |
Atypical presentations of Pneumocystis carinii pneumonia in patients receiving inhaled pentamidine prophylaxis.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Bronchoalveolar Lavage Fluid; | 1990 |
Prevention of Pneumocystis carinii pneumonia relapse by aerosolised pentamidine, 60 mg biweekly, using an Acorn System 22 nebuliser.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Humans; Male; Middle Aged; Nebulizers and Vapor | 1990 |
Pneumothoraces and Pneumocystis carinii pneumonia in two AIDS patients receiving aerosolized pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Humans; Male; Pentamidine; Pneumonia, Pneumocys | 1990 |
Domiciliary nebulized pentamidine for secondary prophylaxis against Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Home Care Services; Humans; Male; Nebulizers and Vaporizers; Pen | 1990 |
Aerosolized pentamidine: effect on diagnosis and presentation of Pneumocystis carinii pneumonia.
Topics: Aerosols; Biopsy; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoscopy; Gallium Radioisotopes; HIV In | 1990 |
Compliance and laboratory data predict relapse rate of Pneumocystis carinii pneumonia during prophylaxis with aerosol pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Aged; Female; Humans; Male; Middle Aged; Multiv | 1990 |
[Recurrence of atypical pulmonary pneumocystosis treated with pentamidine aerosol].
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Bronchoalveolar Lavage Fluid; Humans; Male; Pen | 1990 |
Guidelines for prophylaxis against Pneumocystis carinii pneumonia for persons infected with human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Child; Drug Combinations; Female; Humans; Infan | 1989 |
From the Centers for Disease Control. Guidelines for prophylaxis against Pneumocystis carinii pneumonia for persons infected with human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Anti-Bacterial Agents; Child; Drug Combinations | 1989 |
Prevention of Pneumocystis carinii pneumonia by inhaled pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; AIDS-Related Complex; Amidines; Coho | 1989 |
Inhaled pentamidine in Pneumocystis carinii pneumonia.
Topics: Administration, Inhalation; Adult; Amidines; Humans; Injections, Intravenous; Male; Middle Aged; Pen | 1989 |
The outcome of Pneumocystis carinii pneumonia in Danish patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Clinical Protocols; Evaluation Studies as Topic; Humans; Male; O | 1989 |
Pneumocystis carinii pneumonia in Stockholm, Sweden: treatment, outcome, one-year-follow-up and pyrimethamine prophylaxis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Dapsone; Drug Evaluation; Drug Therapy, Combination | 1989 |
Relapse of Pneumocystis carinii pneumonia in the upper lobes during aerosol pentamidine prophylaxis.
Topics: Administration, Inhalation; Adult; Amidines; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; Rec | 1989 |
Experience with pneumocystis carinii pneumonia in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Bronchoscopy; Drug Combinations; Follow-Up Studies; Homos | 1989 |
Digital necrosis and disseminated Pneumocystis carinii infection after aerosolized pentamidine prophylaxis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Humans; Male; Mycoses; Necrosis; Pentamidine; P | 1989 |
Differences in relative efficiency of nebulisers for pentamidine administration.
Topics: Amidines; HIV Seropositivity; Humans; Male; Nebulizers and Vaporizers; Pentamidine; Pneumonia, Pneum | 1988 |
Treatment of Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Dapsone; Drug Combinations; Folic Acid Antagonists; Humans; Meth | 1987 |
Fansidar-associated fatal reaction in an HIV-infected man.
Topics: Drug Combinations; Drug Therapy, Combination; HIV Seropositivity; Homosexuality; Humans; Male; Middl | 1988 |
Aerosolized pentamidine promising in Pneumocystis therapy, prophylaxis.
Topics: Aerosols; Amidines; Humans; Pentamidine; Pneumonia, Pneumocystis; Recurrence | 1988 |
Chemoprophylaxis for Pneumocystis carinii pneumonia in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Amidines; Drug Combinations; Humans; | 1988 |
Leads from the MMWR. Fansidar-associated fatal reaction in an HIV-infected man.
Topics: Drug Combinations; Drug Therapy, Combination; HIV Seropositivity; Homosexuality; Humans; Male; Middl | 1988 |
Recurrent ventricular tachycardia due to pentamidine-induced cardiotoxicity.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Electrocardiography; Heart; Humans; Male; Penta | 1988 |
Atypical presentation of Pneumocystis carinii pneumonia in a patient receiving inhalational pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Amidines; Humans; Male; Penta | 1988 |
The treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Drug Combinations; Drug Therapy, Combination; H | 1985 |
Persistence of pneumocystis.
Topics: Acquired Immunodeficiency Syndrome; Animals; Humans; Pentamidine; Pneumonia, Pneumocystis; Recurrenc | 1985 |
Persistence of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. Evaluation of therapy by follow-up transbronchial lung biopsy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Biopsy; Drug Combinations; Drug Therapy, Combination; Eva | 1985 |