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pentamidine and Pneumothorax, Primary Spontaneous

pentamidine has been researched along with Pneumothorax, Primary Spontaneous in 24 studies

Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

Research Excerpts

ExcerptRelevanceReference
"Aerosolized pentamidine prophylaxis for Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS) may predispose these patients to recurrent apical Pneumocystis infection."7.68Spontaneous pneumothorax in AIDS patients with recurrent Pneumocystis carinii pneumonia despite aerosolized pentamidine prophylaxis. ( Haggerty, MF; Luyckx, BA; Murphy, TF; Shanley, DJ, 1991)
"Spontaneous pneumothorax is a known complication of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome."5.28Spontaneous pneumothorax in patients with acquired immunodeficiency syndrome treated with prophylactic aerosolized pentamidine. ( Newsome, GS; Pierce, PF; Ward, DJ, 1990)
"Aerosolized pentamidine prophylaxis for Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS) may predispose these patients to recurrent apical Pneumocystis infection."3.68Spontaneous pneumothorax in AIDS patients with recurrent Pneumocystis carinii pneumonia despite aerosolized pentamidine prophylaxis. ( Haggerty, MF; Luyckx, BA; Murphy, TF; Shanley, DJ, 1991)
"Two cases of focal recurrent Pneumocystis carinii pneumonia (PCP) associated with pneumothorax occurred in patients with AIDS who had received aerosolized pentamidine therapy."3.68Pneumothoraces and Pneumocystis carinii pneumonia in two AIDS patients receiving aerosolized pentamidine. ( Scannell, KA, 1990)
"Pneumothorax has been reported in several cases."1.37Fatal bilateral pneumothoraces following administration of aerosolised pentamidine. ( Green, A; Milne, N; Ong, BB, 2011)
"Spontaneous pneumothorax is a relatively frequent complication of human immunodeficiency virus (HIV) infection."1.30[Spontaneous pneumothorax associated with human immunodeficiency virus (HIV) infection]. ( Cifrián Martínez, JM; Fernández Rozas, SM; García Pérez, MM; Golpe Gómez, R; Jiménez Gómez, A; Mons Lera, R, 1998)
"Pentamidine 60 mg was administered by ultrasonic nebulization (Fisoneb) five times during the first two weeks and then every two weeks."1.28Bilateral pneumothoraces hasten mortality in AIDS patients receiving secondary prophylaxis with aerosolized pentamidine. Association with a lower Dco prior to receiving aerosolized pentamidine. ( Braidy, J; Chassé, M; Corbeil, C; Matar, N; Renzi, PM, 1992)
"Of 1030 patients with AIDS who were followed at Memorial Sloan-Kettering Cancer Center between 1 January 1980 and 30 September 1989, 20 (2%) developed pneumothorax that was unrelated to trauma or a pulmonary procedure."1.28Pneumothorax in AIDS. ( Armstrong, D; Bernard, EM; Blum, S; Carrow, M; Dickmeyer, M; Gold, JW; Sepkowitz, KA; Telzak, EE, 1991)
"Spontaneous pneumothorax is a known complication of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome."1.28Spontaneous pneumothorax in patients with acquired immunodeficiency syndrome treated with prophylactic aerosolized pentamidine. ( Newsome, GS; Pierce, PF; Ward, DJ, 1990)
"Pneumothorax is a rare complication of Pn."1.28[Pneumothorax as a complication of Pneumocystis carinii pneumonia]. ( Battegay, M; Greminger, P; Lüthy, R, 1989)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.50)18.7374
1990's19 (79.17)18.2507
2000's1 (4.17)29.6817
2010's1 (4.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Green, A1
Milne, N1
Ong, BB1
Konishi, M1
Amimoto, M1
Yoshimoto, E1
Takahashi, K1
Mori, K1
Mikasa, K1
Narita, N1
Partisani, M1
Fraisse, P1
De Mautort, E1
Rey, D1
Lang, JM1
Riquet, M1
Chouaid, C1
Saab, M1
Hubsch, JP1
Guillon, JM1
Klotz, BL1
Carnot, F1
Sylla, G1
Kullean, N1
Lafferre, A1
Mussard, F1
Rossi, P1
Albort, JV1
Callejas, MA1
Canalis, EA1
Catalán, M1
Sanchez-Lloret, J1
Golpe Gómez, R1
Cifrián Martínez, JM1
Fernández Rozas, SM1
García Pérez, MM1
Mons Lera, R1
Jiménez Gómez, A1
Páldy, L1
Ivády, G1
Bagheri, K1
Truitt, TJ1
Safirstein, BH1
Renzi, PM1
Corbeil, C1
Chassé, M1
Braidy, J1
Matar, N1
Cuthbert, AC1
Wright, D1
McVerry, BA1
Squire, SB1
Bagdades, EK1
Lee, CA1
Johnson, MA1
Kennedy, CA1
Shanley, DJ1
Luyckx, BA1
Haggerty, MF1
Murphy, TF1
Sepkowitz, KA1
Telzak, EE1
Gold, JW1
Bernard, EM1
Blum, S1
Carrow, M1
Dickmeyer, M1
Armstrong, D1
de Jong, MD1
Lange, JM1
Smits, NJ1
Reiss, P1
Fortún, J1
Antela, A1
Rey, J1
Montilla, P1
Newsome, GS1
Ward, DJ1
Pierce, PF1
Scannell, KA1
Bouslama, K1
Lebas, J1
Guidet, B1
Denis, M1
Cabane, J1
Picard, O1
Wattiaux, MJ1
Giral, P1
Mayaud, C1
Imbert, JC1
Battegay, M1
Greminger, P1
Lüthy, R1
Martinez, CM1
Romanelli, A1
Mullen, MP1
Lee, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Oral Corticosteroids Therapy and Interstitial Fibrosis in Patients With Pneumocystis Jirovecii Pneumonia (PCP) and pO2 of >70 at Presentation.[NCT00636935]Phase 40 participants (Actual)Interventional2008-02-29Withdrawn (stopped due to No patient completed protocol)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

24 other studies available for pentamidine and Pneumothorax, Primary Spontaneous

ArticleYear
Fatal bilateral pneumothoraces following administration of aerosolised pentamidine.
    Journal of forensic and legal medicine, 2011, Volume: 18, Issue:7

    Topics: Administration, Inhalation; AIDS-Related Opportunistic Infections; Antifungal Agents; Asthma; Forens

2011
AIDS-related Pneumocystis carinii pneumonia with disappearance of cystic lesions after treatment.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:10

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Bronchoalveolar Lavage; Bronchos

2002
[High incidence of bullous pulmonary lesions before pentamidine isethionate aerosols. 35 cases].
    Presse medicale (Paris, France : 1983), 1994, Dec-10, Volume: 23, Issue:39

    Topics: Acquired Immunodeficiency Syndrome; Female; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; Pneu

1994
[Extrapulmonary intrathoracic pneumocystosis. Apropos of 4 cases in HIV positive patients].
    Revue de pneumologie clinique, 1993, Volume: 49, Issue:1

    Topics: Administration, Inhalation; Adult; AIDS-Related Opportunistic Infections; CD4-Positive T-Lymphocytes

1993
[Spontaneous pneumothorax disclosing isolated pleural involvement caused by Pneumocystis carinii in an AIDS patient].
    Revue de pneumologie clinique, 1993, Volume: 49, Issue:1

    Topics: Administration, Inhalation; Adult; AIDS-Related Opportunistic Infections; Humans; Male; Pentamidine;

1993
Surgical management of spontaneous pneumothorax in patients with AIDS.
    The Annals of thoracic surgery, 1993, Volume: 55, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Humans; Pentamidine; Pneumothorax; Recurrence

1993
[Spontaneous pneumothorax associated with human immunodeficiency virus (HIV) infection].
    Archivos de bronconeumologia, 1998, Volume: 34, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Drainage; Female; HIV Infection

1998
Roentgenologic diagnosis of interstitial plasma cell pneumonia in infancy.
    National Cancer Institute monograph, 1976, Volume: 43

    Topics: Diagnosis, Differential; Humans; Infant; Infant, Newborn; Pentamidine; Pneumonia, Pneumocystis; Pneu

1976
Spontaneous pneumothorax in AIDS patients not receiving prophylaxis against Pneumocystis carinii pneumonia.
    Chest, 1992, Volume: 101, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Aerosols; Humans; Pentamidine; Pneumonia, Pneumocystis; Pneumoth

1992
Bilateral pneumothoraces hasten mortality in AIDS patients receiving secondary prophylaxis with aerosolized pentamidine. Association with a lower Dco prior to receiving aerosolized pentamidine.
    Chest, 1992, Volume: 102, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Female; Humans; Lung Volume Measurements; Male;

1992
Pneumothorax in pentamidine-treated haemophiliacs.
    Lancet (London, England), 1991, Apr-13, Volume: 337, Issue:8746

    Topics: Hemophilia A; HIV Seropositivity; Humans; Pentamidine; Pneumonia, Pneumocystis; Pneumothorax

1991
Pneumothorax and aerosolised pentamidine prophylaxis.
    Lancet (London, England), 1991, May-25, Volume: 337, Issue:8752

    Topics: Aerosols; HIV Infections; Humans; Pentamidine; Pneumothorax

1991
Pneumothorax in AIDS.
    Annals of internal medicine, 1991, Aug-15, Volume: 115, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Aerosols; Humans; Pentamidine; Pneumothorax

1991
Spontaneous pneumothorax in AIDS patients with recurrent Pneumocystis carinii pneumonia despite aerosolized pentamidine prophylaxis.
    Chest, 1991, Volume: 99, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Humans; Lung; Male; Middle Aged; Pentamidine; P

1991
Pneumothorax in AIDS.
    Annals of internal medicine, 1991, Mar-15, Volume: 114, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Female; Humans; Male; Multivariate Analysis; Ou

1991
[Pneumocystis carinii infection during prophylaxis with nebulized pentamidine in a patient with AIDS].
    Nederlands tijdschrift voor geneeskunde, 1991, Mar-09, Volume: 135, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Bacterial Agents; Drug Therapy, Combination; Humans;

1991
[Pneumocystis carinii recurrence after the use of prophylactic inhaled pentamidine. The unusual radiological findings].
    Medicina clinica, 1991, May-04, Volume: 96, Issue:17

    Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Heroin Dependence; Humans; Lu

1991
Risk for pneumothorax in AIDS.
    Annals of internal medicine, 1991, Jul-15, Volume: 115, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Aerosols; Humans; Pentamidine; Pneumonia, Pneumocystis; Pneumoth

1991
Spontaneous pneumothorax in patients with acquired immunodeficiency syndrome treated with prophylactic aerosolized pentamidine.
    Archives of internal medicine, 1990, Volume: 150, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Humans; Male; Middle Aged; Pentamidine; Pneumon

1990
Pneumothoraces and Pneumocystis carinii pneumonia in two AIDS patients receiving aerosolized pentamidine.
    Chest, 1990, Volume: 97, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Humans; Male; Pentamidine; Pneumonia, Pneumocys

1990
Aerosolized pentamidine and spontaneous pneumothoraces in AIDS patients.
    Chest, 1990, Volume: 97, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Humans; Pentamidine; Pneumonia, Pneumocystis; Pneumothorax

1990
[Recurrence of atypical pulmonary pneumocystosis treated with pentamidine aerosol].
    Annales de medecine interne, 1990, Volume: 141, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Bronchoalveolar Lavage Fluid; Humans; Male; Pen

1990
[Pneumothorax as a complication of Pneumocystis carinii pneumonia].
    Deutsche medizinische Wochenschrift (1946), 1989, Oct-13, Volume: 114, Issue:41

    Topics: Adult; Female; HIV Seropositivity; Humans; Pentamidine; Pneumonia, Pneumocystis; Pneumothorax; Radio

1989
Spontaneous pneumothoraces in AIDS patients receiving aerosolized pentamidine.
    Chest, 1988, Volume: 94, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Aerosols; Amidines; Humans; Pentamidine; Pneumonia, Pneumocystis

1988