pentamidine has been researched along with Parasitemia in 11 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Parasitemia: The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Suramin was not effective." | 1.39 | Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi. ( Bucheton, B; Courtois, P; Cuny, G; Daulouède, S; Dethoua, M; Nzoumbou-Boko, R; Semballa, S; Truc, P; Vincendeau, P, 2013) |
| "The chemotherapy of Chagas disease is quite unsatisfactory mainly due to its poor efficacy especially during the later chronic phase and the considerable well-known side effects." | 1.37 | Trypanocidal activity and selectivity in vitro of aromatic amidine compounds upon bloodstream and intracellular forms of Trypanosoma cruzi. ( Arafa, RK; Boykin, DW; da Silva, PB; De Souza, EM; Ismail, MA; Nefertiti, AS; Nixon-Smith, CK; Soeiro, MN; Tao, B, 2011) |
| " Furthermore, these compounds distributed to target tissues (liver and spleen) and had a moderate oral bioavailability (up to 25%), a large volume of distribution, and an elimination half-life ranging from 1 to 2 days in mice." | 1.36 | Novel arylimidamides for treatment of visceral leishmaniasis. ( Boykin, DW; Hall, JE; Kyle, DE; Liu, Q; Madhubala, R; Mandal, S; Munde, M; Pandharkar, T; Parman, T; Riccio, E; Srivastava, A; Stephens, CE; Sweat, JM; Tidwell, RR; Wang, MZ; Werbovetz, KA; Wilson, WD; Zhu, X, 2010) |
| "This report describes a case of West African trypanosomiasis involving a Caucasian Frenchman living in Conackry, Guinea." | 1.31 | [Human African trypanosomiasis from Trypanosoma brucei gambiense with inoculation chancre in a French expatriate]. ( Chapuis, P; Djossou, F; Le Bras, M; Longy-Boursier, M; Malvy, D; Weill, FX, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, MZ | 1 |
| Zhu, X | 1 |
| Srivastava, A | 1 |
| Liu, Q | 1 |
| Sweat, JM | 1 |
| Pandharkar, T | 1 |
| Stephens, CE | 1 |
| Riccio, E | 1 |
| Parman, T | 1 |
| Munde, M | 1 |
| Mandal, S | 1 |
| Madhubala, R | 1 |
| Tidwell, RR | 2 |
| Wilson, WD | 1 |
| Boykin, DW | 2 |
| Hall, JE | 1 |
| Kyle, DE | 1 |
| Werbovetz, KA | 1 |
| Dethoua, M | 1 |
| Nzoumbou-Boko, R | 1 |
| Truc, P | 1 |
| Daulouède, S | 1 |
| Courtois, P | 1 |
| Bucheton, B | 1 |
| Cuny, G | 1 |
| Semballa, S | 1 |
| Vincendeau, P | 1 |
| Deschamps, JY | 1 |
| Desquesnes, M | 1 |
| Dorso, L | 1 |
| Ravel, S | 1 |
| Bossard, G | 1 |
| Charbonneau, M | 1 |
| Garand, A | 1 |
| Roux, FA | 1 |
| Seguel, V | 1 |
| Castro, L | 1 |
| Reigada, C | 1 |
| Cortes, L | 1 |
| Díaz, MV | 1 |
| Miranda, MR | 1 |
| Pereira, CA | 1 |
| Lapier, M | 1 |
| Campos-Estrada, C | 1 |
| Morello, A | 1 |
| Kemmerling, U | 1 |
| Maya, JD | 1 |
| López-Muñoz, R | 1 |
| De Souza, EM | 1 |
| da Silva, PB | 1 |
| Nefertiti, AS | 1 |
| Ismail, MA | 1 |
| Arafa, RK | 1 |
| Tao, B | 1 |
| Nixon-Smith, CK | 1 |
| Soeiro, MN | 1 |
| Nehrbass-Stuedli, A | 1 |
| Boykin, D | 1 |
| Brun, R | 1 |
| Roscoe, M | 1 |
| Löhr, FK | 1 |
| Otieno, PS | 1 |
| Gacanga, W | 1 |
| Suzuki, T | 1 |
| Ueta, YY | 1 |
| Inoue, N | 1 |
| Xuan, X | 1 |
| Saitoh, H | 1 |
| Suzuki, H | 1 |
| Loiseau, PM | 1 |
| Gutierrez-Rios, MT | 1 |
| De Frutos, MI | 1 |
| Craciunescu, DG | 1 |
| Malvy, D | 1 |
| Djossou, F | 1 |
| Weill, FX | 1 |
| Chapuis, P | 1 |
| Longy-Boursier, M | 1 |
| Le Bras, M | 1 |
1 review available for pentamidine and Parasitemia
| Article | Year |
|---|---|
Leishmaniasis: early diagnosis is key.
Topics: Animals; Antimony; Antiprotozoal Agents; Diagnosis, Differential; Early Diagnosis; Humans; Leishmani | 2005 |
10 other studies available for pentamidine and Parasitemia
| Article | Year |
|---|---|
Novel arylimidamides for treatment of visceral leishmaniasis.
Topics: Amidines; Animals; Antiprotozoal Agents; Biological Availability; Cricetinae; Disease Models, Animal | 2010 |
Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi.
Topics: Animals; Eflornithine; Female; Humans; Immunocompromised Host; Inhibitory Concentration 50; Melarsop | 2013 |
Refractory hypoglycaemia in a dog infected with Trypanosoma congolense.
Topics: Africa South of the Sahara; Animals; Antiprotozoal Agents; Dog Diseases; Dogs; Female; Fever; Glucos | 2016 |
Pentamidine antagonizes the benznidazole's effect in vitro, and lacks of synergy in vivo: Implications about the polyamine transport as an anti-Trypanosoma cruzi target.
Topics: Animals; Chagas Disease; Chlorocebus aethiops; DNA, Protozoan; Dose-Response Relationship, Drug; Glu | 2016 |
Trypanocidal activity and selectivity in vitro of aromatic amidine compounds upon bloodstream and intracellular forms of Trypanosoma cruzi.
Topics: Amidines; Animals; Chagas Disease; Dose-Response Relationship, Drug; Lethal Dose 50; Mice; Myocytes, | 2011 |
Novel diamidines with activity against Babesia divergens in vitro and Babesia microti in vivo.
Topics: Animals; Antiprotozoal Agents; Babesia; Babesia microti; Babesiosis; Benzimidazoles; Female; Furans; | 2011 |
Therapy trial using betamethasone in addition to specific treatment with a diamidine and quinuronium derivate in cattle experimentally infected with Babesia bigemina.
Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Betamethasone; Cattle; Cattle Diseases; Organ Sp | 1976 |
Beneficial effect of erythropoietin administration on murine infection with Trypanosoma congolense.
Topics: Anemia; Animals; Antibodies, Monoclonal; DNA Primers; DNA Probes; Erythropoietin; Female; Gene Expre | 2006 |
Structure-activity relationships for new organometallic complexes active against bloodstream forms of Trypanosoma brucei brucei.
Topics: Animals; Disease Models, Animal; Female; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Orga | 2001 |
[Human African trypanosomiasis from Trypanosoma brucei gambiense with inoculation chancre in a French expatriate].
Topics: Animals; Antibodies, Protozoan; Erythema; Fever; France; Guinea; Humans; Immunoglobulin G; Immunoglo | 2001 |