pentamidine has been researched along with P carinii Infection in 35 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The incidences of pentamidine-associated nephrotoxicity and hyperkalemia were determined from a retrospective review of records in AIDS patients using standard definitions for both toxicities." | 7.68 | Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS. ( Bailie, GR; Briceland, LL, 1991) |
| "Pneumocystis carinii infection of the thyroid gland has previously been described in only four living patients with acquired immunodeficiency syndrome, three of whom had been receiving inhaled pentamidine prophylaxis against P carinii pneumonia." | 4.78 | Pneumocystis carinii thyroiditis. Report of three cases and review of the literature. ( Axline, SG; Greaves, TS; Guttler, R; McGill, JJ; Singer, PA, 1993) |
| "The incidences of pentamidine-associated nephrotoxicity and hyperkalemia were determined from a retrospective review of records in AIDS patients using standard definitions for both toxicities." | 3.68 | Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS. ( Bailie, GR; Briceland, LL, 1991) |
| "Pneumothorax has been reported in several cases." | 1.37 | Fatal bilateral pneumothoraces following administration of aerosolised pentamidine. ( Green, A; Milne, N; Ong, BB, 2011) |
| "We report a case of splenic pneumocystosis in a human immunodeficiency virus-positive individual treated prophylactically with aerosolized pentamidine." | 1.29 | [Extra-pulmonary pneumocystosis in the course of AIDS. Report of a case]. ( Marche, C; Potet, F; Terris, B, 1996) |
| "Choroiditis was a preterminal diagnosis for three patients--two with associated disseminated pneumocystosis." | 1.28 | Pneumocystis carinii choroiditis in patients with AIDS: clinical features, response to therapy, and outcome. ( Benson, CA; Deutsch, T; Finn, WG; Kessler, HA; Murphy, RL; Noskin, GA; Pottage, JC; Roth, SI; Sha, BE, 1992) |
| "Extrapulmonary Pneumocystis carinii infections in AIDS are still rare although the number of cases is increasing." | 1.28 | Dissemination of Pneumocystis carinii in patients with AIDS. ( Junge, J; Nielsen, TN; Witt, K, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 30 (85.71) | 18.2507 |
| 2000's | 4 (11.43) | 29.6817 |
| 2010's | 1 (2.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boykin, DW | 1 |
| Kumar, A | 1 |
| Spychala, J | 1 |
| Zhou, M | 1 |
| Lombardy, RJ | 1 |
| Wilson, WD | 1 |
| Dykstra, CC | 1 |
| Jones, SK | 1 |
| Hall, JE | 1 |
| Tidwell, RR | 1 |
| O'Neal, CB | 1 |
| Ball, SC | 1 |
| Green, A | 1 |
| Milne, N | 1 |
| Ong, BB | 1 |
| Rodriguez, M | 1 |
| Fishman, JA | 2 |
| O'Leary, TJ | 1 |
| Tsai, MM | 1 |
| Wright, CF | 1 |
| Cushion, MT | 2 |
| MartÃnez, MJ | 1 |
| de Otero, J | 1 |
| Vallano, A | 1 |
| Ribera, E | 1 |
| Hughes, WT | 1 |
| Killmar, JT | 1 |
| Oz, HS | 1 |
| Contini, C | 1 |
| Romani, R | 1 |
| Vullo, V | 1 |
| Delia, S | 1 |
| Sorice, F | 1 |
| Riquet, M | 1 |
| Chouaid, C | 1 |
| Saab, M | 1 |
| Hubsch, JP | 1 |
| Guillon, JM | 1 |
| Klotz, BL | 1 |
| Carnot, F | 1 |
| Lalonde, L | 1 |
| Allaire, GS | 1 |
| Sebag, M | 1 |
| Lamer, L | 1 |
| Marcil, G | 1 |
| Gervais, A | 1 |
| Sylla, G | 1 |
| Kullean, N | 1 |
| Lafferre, A | 1 |
| Mussard, F | 1 |
| Rossi, P | 1 |
| Jayes, RL | 1 |
| Kamerow, HN | 1 |
| Hasselquist, SM | 1 |
| Delaney, MD | 1 |
| Parenti, DM | 1 |
| Guttler, R | 1 |
| Singer, PA | 1 |
| Axline, SG | 1 |
| Greaves, TS | 1 |
| McGill, JJ | 1 |
| Ng, VL | 1 |
| Geaghan, SM | 1 |
| Leoung, G | 1 |
| Shiboski, S | 1 |
| Fahy, J | 1 |
| Schnapp, L | 1 |
| Yajko, DM | 1 |
| Hopewell, PC | 1 |
| Hadley, WK | 1 |
| Bazin, C | 1 |
| Hazera, P | 1 |
| Greder, A | 1 |
| Cren, P | 1 |
| Lechevalier, B | 1 |
| Gallet, E | 1 |
| Charbonneau, P | 1 |
| Boldorini, R | 1 |
| Guzzetti, S | 1 |
| Meroni, L | 1 |
| Quirino, T | 1 |
| Cristina, S | 1 |
| Monga, G | 1 |
| Terris, B | 1 |
| Marche, C | 1 |
| Potet, F | 1 |
| Kaplanski, G | 1 |
| Granel, B | 1 |
| Di Stefano, D | 1 |
| Durand, JM | 1 |
| Soubeyrand, J | 1 |
| Coyle, P | 1 |
| Carr, AD | 1 |
| Depczynski, BB | 1 |
| Chisholm, DJ | 1 |
| Yoshida, EM | 1 |
| Filipenko, D | 1 |
| Phillips, P | 1 |
| Montaner, JS | 1 |
| Whittaker, JS | 1 |
| Machado, CM | 1 |
| Macedo, MC | 1 |
| Medeiros, RS | 1 |
| Massumoto, C | 1 |
| Silva, AC | 1 |
| Castelli, JB | 1 |
| Silva, RL | 1 |
| Ostronoff, M | 1 |
| Dulley, FL | 1 |
| Taguchi, H | 1 |
| Takahashi, T | 1 |
| Wada, Y | 1 |
| Nakamura, T | 1 |
| Iwamoto, A | 1 |
| Ioannidis, JP | 1 |
| Dixon, DO | 1 |
| McIntosh, M | 1 |
| Albert, JM | 1 |
| Bozzette, SA | 1 |
| Schnittman, SM | 1 |
| Collins, M | 1 |
| Hazra, B | 1 |
| Kaneshiro, ES | 1 |
| Vasconcelles, MJ | 1 |
| Bernardo, MV | 1 |
| King, C | 1 |
| Weller, EA | 1 |
| Antin, JH | 1 |
| Dieterich, DT | 1 |
| Lew, EA | 1 |
| Bacon, DJ | 1 |
| Pearlman, KI | 1 |
| Scholes, JV | 1 |
| Sha, BE | 1 |
| Benson, CA | 1 |
| Deutsch, T | 1 |
| Noskin, GA | 1 |
| Murphy, RL | 1 |
| Pottage, JC | 1 |
| Finn, WG | 1 |
| Roth, SI | 1 |
| Kessler, HA | 1 |
| Fan-Havard, P | 1 |
| Balembits, B | 1 |
| Koudobine, L | 1 |
| DeRoux, SJ | 1 |
| Adsay, NV | 1 |
| Ioachim, HL | 1 |
| Briceland, LL | 1 |
| Bailie, GR | 1 |
| Witt, K | 1 |
| Nielsen, TN | 1 |
| Junge, J | 1 |
| Foster, RE | 1 |
| Lowder, CY | 1 |
| Meisler, DM | 1 |
| Huang, SS | 1 |
| Longworth, DL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial of Three Anti-Pneumocystis Agents Plus Zidovudine for the Primary Prevention of Serious Infections in Patients With Advanced HIV Infection[NCT00000991] | Phase 3 | 600 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for pentamidine and P carinii Infection
| Article | Year |
|---|---|
Prevention of infection due to Pneumocystis spp. in human immunodeficiency virus-negative immunocompromised patients.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Bone Marrow Transplantation; Humans; Immun | 2004 |
Pneumocystis carinii thyroiditis. Report of three cases and review of the literature.
Topics: Adult; AIDS-Related Opportunistic Infections; Humans; Male; Pentamidine; Pneumocystis Infections; Pn | 1993 |
Treatment of infection due to Pneumocystis carinii.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Atovaquone; Clindamycin; Dapsone; Eflornithine; Humans | 1998 |
Gastrointestinal pneumocystosis in HIV-infected patients on aerosolized pentamidine: report of five cases and literature review.
Topics: Adult; Aerosols; Gastrointestinal Diseases; HIV Infections; Humans; Male; Middle Aged; Pentamidine; | 1992 |
1 trial available for pentamidine and P carinii Infection
| Article | Year |
|---|---|
Aerosolized pentamidine as pneumocystis prophylaxis after bone marrow transplantation is inferior to other regimens and is associated with decreased survival and an increased risk of other infections.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosol Propellants; Aged; Antifungal Agents; Bone Ma | 2000 |
30 other studies available for pentamidine and P carinii Infection
| Article | Year |
|---|---|
Dicationic diarylfurans as anti-Pneumocystis carinii agents.
Topics: Animals; Antifungal Agents; Base Sequence; Binding Sites; Cations; DNA, Protozoan; Furans; Giardia l | 1995 |
Splenic pneumocystosis: an atypical presentation of extrapulmonary Pneumocystis infection.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antifungal Agents; Atovaquone; Female | 2008 |
Fatal bilateral pneumothoraces following administration of aerosolised pentamidine.
Topics: Administration, Inhalation; AIDS-Related Opportunistic Infections; Antifungal Agents; Asthma; Forens | 2011 |
Drugs for AIDS and associated infections.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifunga | 1995 |
Use of semiquantitative PCR to assess onset and treatment of Pneumocystis carinii infection in rat model.
Topics: Animals; Base Sequence; Bronchoalveolar Lavage Fluid; DNA, Fungal; Immunosuppression Therapy; Molecu | 1995 |
[Macroscopic hematuria secondary to the administration of intravenous pentamidine].
Topics: Adult; AIDS-Related Opportunistic Infections; Female; Hematuria; Humans; Injections, Intravenous; Pe | 1995 |
Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model.
Topics: Animals; Anti-Infective Agents; Atovaquone; Azithromycin; Clarithromycin; Clindamycin; Clinical Tria | 1994 |
Detection of Pneumocystis carinii in urinary samples from a patient with AIDS despite prophylactic treatment with aerosolized pentamidine.
Topics: Adult; Aerosols; AIDS-Related Opportunistic Infections; Bacteriuria; Fatal Outcome; Female; Humans; | 1994 |
[Extrapulmonary intrathoracic pneumocystosis. Apropos of 4 cases in HIV positive patients].
Topics: Administration, Inhalation; Adult; AIDS-Related Opportunistic Infections; CD4-Positive T-Lymphocytes | 1993 |
Pneumocystis carinii choroidopathy and aerosolized pentamidine prophylaxis in a patient with AIDS.
Topics: Adult; Aerosols; AIDS-Related Opportunistic Infections; Choroiditis; Eye Infections, Fungal; Humans; | 1993 |
[Spontaneous pneumothorax disclosing isolated pleural involvement caused by Pneumocystis carinii in an AIDS patient].
Topics: Administration, Inhalation; Adult; AIDS-Related Opportunistic Infections; Humans; Male; Pentamidine; | 1993 |
Disseminated pneumocystosis presenting as a pleural effusion.
Topics: Administration, Inhalation; Adult; Humans; Injections, Intravenous; Male; Pentamidine; Pleural Effus | 1993 |
Lack of effect of prophylactic aerosolized pentamidine on the detection of Pneumocystis carinii in induced sputum or bronchoalveolar lavage specimens.
Topics: Aerosols; AIDS-Related Opportunistic Infections; Bronchoalveolar Lavage Fluid; Humans; Pentamidine; | 1993 |
[Extrapulmonary and disseminated pneumocystosis in HIV infection].
Topics: Adult; AIDS-Related Opportunistic Infections; Bone Marrow Diseases; Female; HIV Infections; Humans; | 1993 |
Acute hepatic and renal failure caused by Pneumocystis carinii in patients with AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Fatal Outcome; Female; Humans; Live | 1995 |
[Extra-pulmonary pneumocystosis in the course of AIDS. Report of a case].
Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Bronchoalveolar Lavage Fluid; Femal | 1996 |
Pleural pseudotumoral mass revealing an extrapulmonary Pneumocystis carinii infection.
Topics: Adult; Aerosols; AIDS-Related Opportunistic Infections; Antifungal Agents; Diagnosis, Differential; | 1996 |
Diabetes mellitus associated with pentamidine use in HIV-infected patients.
Topics: Adult; Antifungal Agents; Diabetes Complications; Diabetes Mellitus; Humans; Middle Aged; Pentamidin | 1996 |
AIDS-related extrapulmonary Pneumocystis carinii infection presenting as a solitary rectal ulcer.
Topics: Adult; Aerosols; AIDS-Related Opportunistic Infections; Antifungal Agents; Biopsy; Humans; Male; Pen | 1996 |
Primary Pneumocystis carinii prophylaxis with aerosolized pentamidine after bone marrow transplantation.
Topics: Aerosols; Bone Marrow Transplantation; Female; Humans; Immunocompromised Host; Male; Pentamidine; Pn | 1998 |
Pentamidine-induced hemolytic anemia in an AIDS patient.
Topics: AIDS-Related Opportunistic Infections; Anemia, Hemolytic; Antifungal Agents; Humans; Male; Middle Ag | 1999 |
Relationship between event rates and treatment effects in clinical site differences within multicenter trials: an example from primary Pneumocystis carinii prophylaxis.
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Controlled Clinical Trials as Topic; D | 1999 |
Effects of atovaquone and diospyrin-based drugs on the cellular ATP of Pneumocystis carinii f. sp. carinii.
Topics: Adenosine Triphosphate; Animals; Antifungal Agents; Atovaquone; Dose-Response Relationship, Drug; Ma | 2000 |
Pneumocystis carinii choroiditis in patients with AIDS: clinical features, response to therapy, and outcome.
Topics: Adult; AIDS-Related Opportunistic Infections; Choroiditis; Eye; Female; Humans; Male; Pentamidine; P | 1992 |
Pneumocystis carinii in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Contraindications; Humans; Nursing, Practical; Opportunistic Inf | 1992 |
[Pentacarinat as an aerosol].
Topics: Aerosols; Humans; Pentamidine; Pneumocystis Infections | 1992 |
Disseminated pneumocystosis without pulmonary involvement during prophylactic aerosolized pentamidine therapy in a patient with the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Autopsy; Humans; Male; Middle Aged; | 1991 |
Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Monitoring; Female; HIV Infections; Humans; Hyperkal | 1991 |
Dissemination of Pneumocystis carinii in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Aerosols; Humans; Kidney; Liver; Lung; Male; Middle Aged; Pentam | 1991 |
Presumed Pneumocystis carinii choroiditis. Unifocal presentation, regression with intravenous pentamidine, and choroiditis recurrence.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Choroiditis; Eye Infections, | 1991 |