pentamidine has been researched along with Liver Failure, Acute in 1 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentamidine is an effective antimicrobial agent against several human pathogens, but studies have also suggested that this drug inhibits inflammation." | 1.46 | Pentamidine blocks hepatotoxic injury in mice. ( Choi, JH; Cingolani, F; Czaja, MJ; Ilyas, G; Ravenelle, F; Tanaka, KE; Zhao, E, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, E | 1 |
| Ilyas, G | 1 |
| Cingolani, F | 1 |
| Choi, JH | 1 |
| Ravenelle, F | 1 |
| Tanaka, KE | 1 |
| Czaja, MJ | 1 |
1 other study available for pentamidine and Liver Failure, Acute
| Article | Year |
|---|---|
Pentamidine blocks hepatotoxic injury in mice.
Topics: Animals; Biopsy, Needle; Blotting, Western; Cytokines; Disease Models, Animal; Galactosamine; Immuno | 2017 |