pentamidine has been researched along with Leukemia, Myeloid, Acute in 6 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentamidine isethionate induced torsades de pointes in a 33-year-old woman with acute myelogenous leukemia." | 7.69 | Torsades de pointes complicating pentamidine therapy of Pneumocystis carinii pneumonia in acute myelogenous leukemia. ( Harano, H; Kanamori, H; Matsuzaki, M; Mohri, H; Ochiai, H; Ogawa, K; Okubo, T; Otsuka, M; Sasaki, S; Sumita, S; Taguchi, J, 1997) |
| "Treatment with pentamidine was stopped and emergent treatment was started." | 5.30 | [Acute myelogenous leukemia with hyperkalemia induced by pentamidine administration]. ( Hino, M; Kumura, T; Nakao, T; Ohta, K; Tatsumi, N; Yamane, T, 1998) |
| "Pentamidine isethionate induced torsades de pointes in a 33-year-old woman with acute myelogenous leukemia." | 3.69 | Torsades de pointes complicating pentamidine therapy of Pneumocystis carinii pneumonia in acute myelogenous leukemia. ( Harano, H; Kanamori, H; Matsuzaki, M; Mohri, H; Ochiai, H; Ogawa, K; Okubo, T; Otsuka, M; Sasaki, S; Sumita, S; Taguchi, J, 1997) |
| "The majority of children with acute lymphoblastic leukemia (ALL; 12 of 14 [86%]) undergoing maintenance chemotherapy were able to resume full-dose therapy." | 2.67 | Successful Pneumocystis carinii pneumonia prophylaxis using aerosolized pentamidine in children with acute leukemia. ( Briones, G; Cairo, MS; Frost, JD; Weinthal, J, 1994) |
| "Treatment with pentamidine was stopped and emergent treatment was started." | 1.30 | [Acute myelogenous leukemia with hyperkalemia induced by pentamidine administration]. ( Hino, M; Kumura, T; Nakao, T; Ohta, K; Tatsumi, N; Yamane, T, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Antony-Debré, I | 1 |
| Paul, A | 1 |
| Leite, J | 1 |
| Mitchell, K | 1 |
| Kim, HM | 1 |
| Carvajal, LA | 1 |
| Todorova, TI | 1 |
| Huang, K | 1 |
| Kumar, A | 1 |
| Farahat, AA | 1 |
| Bartholdy, B | 1 |
| Narayanagari, SR | 1 |
| Chen, J | 1 |
| Ambesi-Impiombato, A | 1 |
| Ferrando, AA | 1 |
| Mantzaris, I | 1 |
| Gavathiotis, E | 1 |
| Verma, A | 1 |
| Will, B | 1 |
| Boykin, DW | 1 |
| Wilson, WD | 1 |
| Poon, GM | 1 |
| Steidl, U | 1 |
| O'Sullivan, BP | 1 |
| Spaulding, R | 1 |
| Weinthal, J | 1 |
| Frost, JD | 1 |
| Briones, G | 1 |
| Cairo, MS | 1 |
| Otsuka, M | 1 |
| Kanamori, H | 1 |
| Sasaki, S | 1 |
| Taguchi, J | 1 |
| Harano, H | 1 |
| Ogawa, K | 1 |
| Matsuzaki, M | 1 |
| Mohri, H | 1 |
| Okubo, T | 1 |
| Sumita, S | 1 |
| Ochiai, H | 1 |
| Kumura, T | 1 |
| Yamane, T | 1 |
| Ohta, K | 1 |
| Nakao, T | 1 |
| Hino, M | 1 |
| Tatsumi, N | 1 |
| Stark, FR | 1 |
| Crast, F | 1 |
| Clemmer, T | 1 |
| Ramirez, R | 1 |
2 trials available for pentamidine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
The use of aerosolized pentamidine for prophylaxis of Pneumocystis carinii pneumonia in children with leukemia.
Topics: Adolescent; Aerosols; Child; Child, Preschool; Dose-Response Relationship, Drug; Humans; Immunosuppr | 1994 |
Successful Pneumocystis carinii pneumonia prophylaxis using aerosolized pentamidine in children with acute leukemia.
Topics: Administration, Inhalation; Adolescent; Aerosols; Child; Child, Preschool; Humans; Immunosuppressive | 1994 |
4 other studies available for pentamidine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Pharmacological inhibition of the transcription factor PU.1 in leukemia.
Topics: Allosteric Regulation; Animals; Apoptosis; Chromatin; HEK293 Cells; Humans; Leukemia, Myeloid, Acute | 2017 |
Torsades de pointes complicating pentamidine therapy of Pneumocystis carinii pneumonia in acute myelogenous leukemia.
Topics: Adult; Antifungal Agents; Cardiac Pacing, Artificial; Electrocardiography; Female; Follow-Up Studies | 1997 |
[Acute myelogenous leukemia with hyperkalemia induced by pentamidine administration].
Topics: Adult; Antifungal Agents; Bone Marrow Transplantation; Humans; Hyperkalemia; Immunocompromised Host; | 1998 |
Letter: Fatal Herxheimer reaction after pentamidine in Pneumocystis pneumonia.
Topics: Adolescent; Amidines; Drug Therapy; Humans; Leukemia, Myeloid, Acute; Male; Pentamidine; Pneumonia, | 1976 |