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pentamidine and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

pentamidine has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 1 studies

Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.

Research Excerpts

ExcerptRelevanceReference
"Pentamidine (PMD) is an anti-protozoa drug with potential anticancer activity."1.38Pentamidine sensitizes chronic myelogenous leukemia K562 cells to TRAIL-induced apoptosis. ( Jiang, J; Liu, XS; Qiu, G, 2012)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Qiu, G1
Jiang, J1
Liu, XS1

Other Studies

1 other study available for pentamidine and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

ArticleYear
Pentamidine sensitizes chronic myelogenous leukemia K562 cells to TRAIL-induced apoptosis.
    Leukemia research, 2012, Volume: 36, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Proliferation; Cell Survival; Humans; K562

2012
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