pentamidine has been researched along with Leucocythaemia in 12 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aerodigestive adverse effects (AD-AE) during intravenous pentamidine (IV-P) infusion for Pneumocystis jiroveci pneumonia prophylaxis are uncommon in retrospective chart review studies." | 1.62 | Aerodigestive adverse effects during intravenous pentamidine infusion for Pneumocystis jirovecii pneumonia prophylaxis. ( George, A; McGraw, BJ; Rademacher, H; Savaşan, S; Sokolowski, C, 2021) |
| "No toxic side effects and no pneumocystis carinii pneumonia were observed." | 1.28 | [Initial experiences with pentamidine aerosol in prevention of Pneumocystis carinii pneumonia following bone marrow transplantation]. ( Ehninger, G; Haen, M; Link, H; Schwardt, A; Vöhringer, HF; Wingen, FJ, 1990) |
| "Between 1976 and 1983, 53 cases of Pneumocystis carinii pneumonia were documented at the Mayo Clinic." | 1.27 | Pneumocystis carinii pneumonia. Review of 53 cases. ( Peters, SG; Prakash, UB, 1987) |
| "Analysis of 194 patients with confirmed Pneumocystis carinii pneumonia in the United States over a 3-year period revealed that P." | 1.26 | Pneumocystis carinii pneumonia in the United States: epidemiologic, diagnostic, and clinical features. ( Krogstad, DJ; Perl, DP; Rawson, PG; Schultz, MG; Walzer, PD, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Eadsforth, TC | 1 |
| Pinto, A | 1 |
| Luciani, R | 1 |
| Tamborini, L | 1 |
| Cullia, G | 1 |
| De Micheli, C | 1 |
| Marinelli, L | 1 |
| Cosconati, S | 1 |
| Novellino, E | 1 |
| Lo Presti, L | 1 |
| Cordeiro da Silva, A | 1 |
| Conti, P | 1 |
| Hunter, WN | 1 |
| Costi, MP | 1 |
| Savaşan, S | 1 |
| George, A | 1 |
| Sokolowski, C | 1 |
| McGraw, BJ | 1 |
| Rademacher, H | 1 |
| Yan, L | 1 |
| Yan, C | 1 |
| Qian, K | 1 |
| Su, H | 1 |
| Kofsky-Wofford, SA | 1 |
| Lee, WC | 1 |
| Zhao, X | 1 |
| Ho, MC | 1 |
| Ivanov, I | 1 |
| Zheng, YG | 1 |
| Milstone, AM | 1 |
| Balakrishnan, SL | 1 |
| Foster, CB | 1 |
| Chen, A | 1 |
| Siegel, SE | 1 |
| Wolff, LJ | 1 |
| Baehner, RL | 1 |
| Hammond, D | 1 |
| Tadesse, A | 1 |
| Gebre-Hiwot, A | 1 |
| Asres, K | 1 |
| Djote, M | 1 |
| Frommel, D | 1 |
| Link, H | 2 |
| Vöhringer, HF | 2 |
| Wingen, F | 1 |
| Brägas, B | 1 |
| Schwardt, A | 2 |
| Ehninger, G | 2 |
| DeVita, VT | 1 |
| Goodell, B | 1 |
| Hubbard, S | 1 |
| Geelhoed, GW | 1 |
| Young, RC | 1 |
| Walzer, PD | 1 |
| Perl, DP | 1 |
| Krogstad, DJ | 1 |
| Rawson, PG | 1 |
| Schultz, MG | 1 |
| Helmer, RE | 1 |
| Wingen, FJ | 1 |
| Haen, M | 1 |
| Peters, SG | 1 |
| Prakash, UB | 1 |
1 trial available for pentamidine and Leucocythaemia
| Article | Year |
|---|---|
Treatment of Pneumocystis carinii pneumonitis. A comparative trial of sulfamethoxazole-trimethoprim v pentamidine in pediatric patients with cancer: report from the Children's Cancer Study Group.
Topics: Acute Disease; Adolescent; Adult; Amidines; Child; Child, Preschool; Clinical Trials as Topic; Drug | 1984 |
11 other studies available for pentamidine and Leucocythaemia
| Article | Year |
|---|---|
Characterization of 2,4-Diamino-6-oxo-1,6-dihydropyrimidin-5-yl Ureido Based Inhibitors of Trypanosoma brucei FolD and Testing for Antiparasitic Activity.
Topics: Animals; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Humans; Leukemia; Macrophages; Meth | 2015 |
Aerodigestive adverse effects during intravenous pentamidine infusion for Pneumocystis jirovecii pneumonia prophylaxis.
Topics: Adolescent; Adult; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, | 2021 |
Diamidine compounds for selective inhibition of protein arginine methyltransferase 1.
Topics: Binding, Competitive; Catalytic Domain; Cell Line, Tumor; Cell Membrane Permeability; Cell Prolifera | 2014 |
Failure of intravenous pentamidine prophylaxis to prevent pneumocystis pneumonia in a pediatric hematopoietic stem cell transplant (HSCT) patient.
Topics: Acute Disease; Antibiotic Prophylaxis; Disease Progression; Fatal Outcome; Hematopoietic Stem Cell T | 2006 |
The in vitro activity of Vernonia amygdalina on Leishmania aethiopica.
Topics: Animals; Biological Assay; Cell Line; Chloroform; Colorimetry; Drug Evaluation, Preclinical; Ethiopi | 1993 |
Pentamidine aerosol for prophylaxis of Pneumocystis carinii pneumonia after BMT.
Topics: Administration, Inhalation; Adult; Bone Marrow Transplantation; Female; Hodgkin Disease; Humans; Leu | 1993 |
Pneumocystis pneumonia in patients with cancer: clinical setting.
Topics: Adrenal Cortex Hormones; Diagnosis, Differential; Humans; Immunologic Deficiency Syndromes; Immunosu | 1976 |
Pneumocystis carinii pneumonia in the United States: epidemiologic, diagnostic, and clinical features.
Topics: Adolescent; Adult; Age Factors; Aged; Black People; Child; Child, Preschool; Female; Humans; Immunol | 1976 |
Hazard of folinic acid with pyrimethamine and sulfadiazine.
Topics: Amidines; Drug Combinations; Drug Interactions; Humans; Leucovorin; Leukemia; Pentamidine; Pneumonia | 1975 |
[Initial experiences with pentamidine aerosol in prevention of Pneumocystis carinii pneumonia following bone marrow transplantation].
Topics: Administration, Inhalation; Adolescent; Adult; Bone Marrow Transplantation; Humans; Leukemia; Lympho | 1990 |
Pneumocystis carinii pneumonia. Review of 53 cases.
Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Drug Combinations; Female; Humans; Leuk | 1987 |