pentamidine has been researched along with Kidney Failure, Chronic in 9 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The literature lacks adequate dosing guidelines for modifying pentamidine therapy in renal failure." | 2.37 | Pentamidine therapy in renal failure: case report and literature review. ( Fitzsimmons, WE; Luskin, SS, 1988) |
| " The peak plasma concentration, plasma clearance, and elimination half-life ranged from 249 +/- 80 to 227 +/- 110 ng/ml, 268 +/- 70 to 329 +/- 58 l/h, and 29 +/- 25 to 118 +/- 119 h, respectively, in groups 1 and 2." | 1.28 | Pharmacokinetics of intravenous pentamidine in patients with normal renal function or receiving hemodialysis. ( Conte, JE, 1991) |
| "carinii pneumonia secondary to AIDS and to other known causes of immune deficiency were enrolled." | 1.27 | Assessment of therapy for pneumocystis carinii pneumonia. PCP Therapy Project Group. ( Haverkos, HW, 1984) |
| "In patients with normal renal function, pentamidine elimination half-life and plasma clearance (mean +/- SD) were 6." | 1.27 | Pentamidine pharmacokinetics in patients with AIDS with impaired renal function. ( Conte, JE; Lin, ET; Upton, RA, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Petruccelli, KC | 1 |
| Couceiro, KN | 1 |
| Guerra, MDGVB | 1 |
| Vasconcelos, ZS | 1 |
| Brandão, ARJ | 1 |
| Silva, MHSE | 1 |
| Guerra, JAO | 1 |
| Lee Loy, J | 1 |
| Koratala, A | 1 |
| De Los Santos, Y | 1 |
| Chamarthi, G | 1 |
| Santos, AH | 1 |
| Alquadan, KF | 1 |
| Rybniker, J | 1 |
| Goede, V | 1 |
| Mertens, J | 1 |
| Ortmann, M | 1 |
| Kulas, W | 1 |
| Kochanek, M | 1 |
| Benzing, T | 1 |
| Arribas, JR | 1 |
| Fätkenheuer, G | 1 |
| Haverkos, HW | 1 |
| Kuller, J | 1 |
| First, MR | 1 |
| D'Achiardi, R | 1 |
| Munda, R | 1 |
| Conte, JE | 2 |
| Green, PT | 1 |
| Reents, S | 1 |
| Harman, E | 1 |
| Curtis, AB | 1 |
| Fitzsimmons, WE | 1 |
| Luskin, SS | 1 |
| Upton, RA | 1 |
| Lin, ET | 1 |
2 reviews available for pentamidine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Treatment of visceral leishmaniasis with intravenous pentamidine and oral fluconazole in an HIV-positive patient with chronic renal failure--a case report and brief review of the literature.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Drug Therapy, Com | 2010 |
Pentamidine therapy in renal failure: case report and literature review.
Topics: Amidines; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pentamidine; Peritoneal Dialysis; Pneu | 1988 |
7 other studies available for pentamidine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Treatment of tegumentary leishmaniasis in two hemodialysis patients with end-stage renal disease using two series of pentamidine.
Topics: Antiprotozoal Agents; Humans; Kidney Failure, Chronic; Leishmaniasis, Cutaneous; Pentamidine; Renal | 2021 |
Disseminated toxoplasmosis: a life-threatening complication of inadequate posttransplant prophylaxis.
Topics: Adult; Antibiotic Prophylaxis; Fatal Outcome; Heart; Humans; Kidney Failure, Chronic; Kidney Transpl | 2019 |
Assessment of therapy for pneumocystis carinii pneumonia. PCP Therapy Project Group.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Amidines; Drug Combinations; Female; Hu | 1984 |
Pneumocystis carinii pneumonia in renal transplant recipients.
Topics: Adolescent; Adult; Drug Combinations; Female; Glomerulonephritis; Graft Rejection; Humans; Kidney Fa | 1982 |
Pharmacokinetics of intravenous pentamidine in patients with normal renal function or receiving hemodialysis.
Topics: Adult; Creatinine; Female; Half-Life; Humans; Infusions, Intravenous; Kidney; Kidney Failure, Chroni | 1991 |
Pentamidine-induced torsades de pointes in a renal transplant recipient with Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Electrocardiography; Female; Humans; Immune Tolerance; Immunosup | 1990 |
Pentamidine pharmacokinetics in patients with AIDS with impaired renal function.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Child; Female; Half-Life; Humans; Infant; Infus | 1987 |