pentamidine has been researched along with Kidney Diseases in 10 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To ascertain the efficacy and toxicity of trimethoprim-sulfamethoxazole or pentamidine when either is given alone during the entire treatment period for Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS)." | 9.06 | Trimethoprim-sulfamethoxazole compared with pentamidine for treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A prospective, noncrossover study. ( Cowan, R; Nielsen, DM; Ruskin, J; Sattler, FR, 1988) |
| "The incidences of pentamidine-associated nephrotoxicity and hyperkalemia were determined from a retrospective review of records in AIDS patients using standard definitions for both toxicities." | 7.68 | Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS. ( Bailie, GR; Briceland, LL, 1991) |
| "We conducted an analysis of 37 patients with the acquired immune deficiency syndrome (AIDS) who received pentamidine for the treatment of Pneumocystis carinii pneumonia to quantitate the incidence and severity of pentamidine-induced hypoglycemia." | 7.67 | Pentamidine-induced hypoglycemia in patients with the acquired immune deficiency syndrome. ( Kalman, CM; Laskin, OL; Stahl-Bayliss, CM, 1986) |
| "To ascertain the efficacy and toxicity of trimethoprim-sulfamethoxazole or pentamidine when either is given alone during the entire treatment period for Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS)." | 5.06 | Trimethoprim-sulfamethoxazole compared with pentamidine for treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A prospective, noncrossover study. ( Cowan, R; Nielsen, DM; Ruskin, J; Sattler, FR, 1988) |
| "The incidences of pentamidine-associated nephrotoxicity and hyperkalemia were determined from a retrospective review of records in AIDS patients using standard definitions for both toxicities." | 3.68 | Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS. ( Bailie, GR; Briceland, LL, 1991) |
| "We conducted an analysis of 37 patients with the acquired immune deficiency syndrome (AIDS) who received pentamidine for the treatment of Pneumocystis carinii pneumonia to quantitate the incidence and severity of pentamidine-induced hypoglycemia." | 3.67 | Pentamidine-induced hypoglycemia in patients with the acquired immune deficiency syndrome. ( Kalman, CM; Laskin, OL; Stahl-Bayliss, CM, 1986) |
| " The primary safety outcome was the frequency and severity of adverse events." | 2.82 | Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial. ( Bernhard, SC; Bilenge, CM; Blum, J; Burri, C; Dala, A; Deo, GK; Dituvanga, ND; Franco, JR; Kuikumbi, FM; Lubaki, JP; Macharia, S; Mesu, VK; Mintwo, AF; Mpanya, A; Mpoto, AM; Munungi, AK; Munungu, BF; Mutantu, PN; N'tombe, PM; Olson, CA; Pohlig, G; Tidwell, RR, 2016) |
| " The dosage was 4 mg/kg/day for 18 days." | 1.28 | Cardiac arrest during treatment of Pneumocystis carinii pneumonia with intravenous pentamidine isethionate. ( Balslev, U; Berild, D; Nielsen, TL, 1992) |
| "Pentamidine was extracted from plasma using a mixed solvent of 40% acetonitrile in chloroform." | 1.27 | High-performance liquid chromatographic method for measurement of pentamidine in plasma and its application in an immunosuppressed patient with renal dysfunction. ( Dusci, LJ; Forbes, AM; Hackett, LP; Ilett, KF, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pohlig, G | 1 |
| Bernhard, SC | 1 |
| Blum, J | 1 |
| Burri, C | 1 |
| Mpanya, A | 1 |
| Lubaki, JP | 1 |
| Mpoto, AM | 1 |
| Munungu, BF | 1 |
| N'tombe, PM | 1 |
| Deo, GK | 1 |
| Mutantu, PN | 1 |
| Kuikumbi, FM | 1 |
| Mintwo, AF | 1 |
| Munungi, AK | 1 |
| Dala, A | 1 |
| Macharia, S | 1 |
| Bilenge, CM | 1 |
| Mesu, VK | 1 |
| Franco, JR | 1 |
| Dituvanga, ND | 1 |
| Tidwell, RR | 1 |
| Olson, CA | 1 |
| Misíková, Z | 1 |
| Kovács, L | 1 |
| Foltinová, A | 1 |
| Balslev, U | 1 |
| Berild, D | 1 |
| Nielsen, TL | 1 |
| Briceland, LL | 1 |
| Bailie, GR | 1 |
| Buff, DD | 1 |
| Aboal, AA | 1 |
| Shah, GM | 1 |
| Alvarado, P | 1 |
| Kirschenbaum, MA | 1 |
| Sattler, FR | 1 |
| Cowan, R | 1 |
| Nielsen, DM | 1 |
| Ruskin, J | 1 |
| Stahl-Bayliss, CM | 1 |
| Kalman, CM | 1 |
| Laskin, OL | 1 |
| Dusci, LJ | 1 |
| Hackett, LP | 1 |
| Forbes, AM | 1 |
| Ilett, KF | 1 |
| Stehr-Green, JK | 1 |
| Helmick, CG | 1 |
2 trials available for pentamidine and Kidney Diseases
| Article | Year |
|---|---|
Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Angola; Benzamidines; Child; Democratic Republic of t | 2016 |
Trimethoprim-sulfamethoxazole compared with pentamidine for treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A prospective, noncrossover study.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Drug Combinations; Hematologic Diseases; Humans | 1988 |
8 other studies available for pentamidine and Kidney Diseases
| Article | Year |
|---|---|
[Nephrotoxic effect of pentamidine in the treatment of interstitial pneumonia in 2 children with acute lymphoblastic leukemia].
Topics: Amidines; Child, Preschool; Humans; Kidney Diseases; Leukemia, Lymphoid; Male; Pentamidine; Pulmonar | 1979 |
Cardiac arrest during treatment of Pneumocystis carinii pneumonia with intravenous pentamidine isethionate.
Topics: Adult; Heart Arrest; Humans; Infusions, Intravenous; Kidney Diseases; Male; Pentamidine; Pneumonia, | 1992 |
Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Monitoring; Female; HIV Infections; Humans; Hyperkal | 1991 |
Pentamidine-associated renal dysfunction and hyperkalemia.
Topics: Acquired Immunodeficiency Syndrome; Humans; Hyperkalemia; Incidence; Kidney Diseases; Pentamidine; P | 1990 |
Symptomatic hypocalcemia and hypomagnesemia with renal magnesium wasting associated with pentamidine therapy in a patient with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adult; Calcium; Humans; Hypocalcemia; Kidne | 1990 |
Pentamidine-induced hypoglycemia in patients with the acquired immune deficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Blood Glucose; Female; Humans; Hypoglycemia; In | 1986 |
High-performance liquid chromatographic method for measurement of pentamidine in plasma and its application in an immunosuppressed patient with renal dysfunction.
Topics: Amidines; Chromatography, High Pressure Liquid; Humans; Immunosuppression Therapy; Kidney Diseases; | 1987 |
Pentamidine and renal toxicity.
Topics: Amidines; Diarrhea; Humans; Injections, Intramuscular; Injections, Intravenous; Kidney Diseases; Pen | 1985 |