pentamidine has been researched along with Hyperkalemia in 8 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Hyperkalemia: Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether pentamidine directly affects the transport of renal ions and thus provides a mechanism for hyperkalemia, which develops in as many as 100% of patients with the acquired immunodeficiency syndrome (AIDS) who receive pentamidine for more than 6 days." | 7.69 | A mechanism for pentamidine-induced hyperkalemia: inhibition of distal nephron sodium transport. ( Kleyman, TR; Ling, BN; Roberts, C, 1995) |
| "The incidences of pentamidine-associated nephrotoxicity and hyperkalemia were determined from a retrospective review of records in AIDS patients using standard definitions for both toxicities." | 7.68 | Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS. ( Bailie, GR; Briceland, LL, 1991) |
| "Recently, the use of pentamidine has risen because of its efficacy in managing patients with acquired immunodeficiency syndrome (AIDS) and Pneumocystis carinii infection." | 7.67 | Nephrotoxicity and hyperkalemia in patients with acquired immunodeficiency syndrome treated with pentamidine. ( Lachaal, M; Venuto, RC, 1989) |
| "Treatment with pentamidine was stopped and emergent treatment was started." | 5.30 | [Acute myelogenous leukemia with hyperkalemia induced by pentamidine administration]. ( Hino, M; Kumura, T; Nakao, T; Ohta, K; Tatsumi, N; Yamane, T, 1998) |
| "To determine whether pentamidine directly affects the transport of renal ions and thus provides a mechanism for hyperkalemia, which develops in as many as 100% of patients with the acquired immunodeficiency syndrome (AIDS) who receive pentamidine for more than 6 days." | 3.69 | A mechanism for pentamidine-induced hyperkalemia: inhibition of distal nephron sodium transport. ( Kleyman, TR; Ling, BN; Roberts, C, 1995) |
| "The incidences of pentamidine-associated nephrotoxicity and hyperkalemia were determined from a retrospective review of records in AIDS patients using standard definitions for both toxicities." | 3.68 | Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS. ( Bailie, GR; Briceland, LL, 1991) |
| "Recently, the use of pentamidine has risen because of its efficacy in managing patients with acquired immunodeficiency syndrome (AIDS) and Pneumocystis carinii infection." | 3.67 | Nephrotoxicity and hyperkalemia in patients with acquired immunodeficiency syndrome treated with pentamidine. ( Lachaal, M; Venuto, RC, 1989) |
| "Treatment with pentamidine was stopped and emergent treatment was started." | 1.30 | [Acute myelogenous leukemia with hyperkalemia induced by pentamidine administration]. ( Hino, M; Kumura, T; Nakao, T; Ohta, K; Tatsumi, N; Yamane, T, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kleyman, TR | 1 |
| Roberts, C | 1 |
| Ling, BN | 1 |
| Kumura, T | 1 |
| Yamane, T | 1 |
| Ohta, K | 1 |
| Nakao, T | 1 |
| Hino, M | 1 |
| Tatsumi, N | 1 |
| Gabriëls, G | 1 |
| Stockem, E | 1 |
| Greven, J | 1 |
| Briceland, LL | 1 |
| Bailie, GR | 1 |
| Buff, DD | 1 |
| Aboal, AA | 1 |
| Marino, PL | 1 |
| Peltz, S | 1 |
| Hashmi, S | 1 |
| Lachaal, M | 1 |
| Venuto, RC | 1 |
1 review available for pentamidine and Hyperkalemia
| Article | Year |
|---|---|
[Hyperkalemia after trimethoprim or pentamidine. Until now, a little noticed side effect of antimicrobial therapeutic measures in AIDS patients].
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antiprotozoal Agents; Folic Acid Antag | 1998 |
7 other studies available for pentamidine and Hyperkalemia
| Article | Year |
|---|---|
A mechanism for pentamidine-induced hyperkalemia: inhibition of distal nephron sodium transport.
Topics: Animals; Biological Transport; Cell Line; Cells, Cultured; Hyperkalemia; Kidney Tubules, Distal; Pen | 1995 |
[Acute myelogenous leukemia with hyperkalemia induced by pentamidine administration].
Topics: Adult; Antifungal Agents; Bone Marrow Transplantation; Humans; Hyperkalemia; Immunocompromised Host; | 1998 |
Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Monitoring; Female; HIV Infections; Humans; Hyperkal | 1991 |
Pentamidine-associated renal dysfunction and hyperkalemia.
Topics: Acquired Immunodeficiency Syndrome; Humans; Hyperkalemia; Incidence; Kidney Diseases; Pentamidine; P | 1990 |
Pentamidine and hyperkalemia revisited.
Topics: Adrenal Insufficiency; Creatinine; Humans; Hyperkalemia; Pentamidine; Potassium | 1990 |
Pentamidine-induced severe hyperkalemia.
Topics: Adult; Humans; Hyperkalemia; Injections, Intramuscular; Male; Pentamidine; Pneumonia, Pneumocystis | 1989 |
Nephrotoxicity and hyperkalemia in patients with acquired immunodeficiency syndrome treated with pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adolescent; Adult; Amidines; Female; Humans | 1989 |