pentamidine has been researched along with Histomoniasis in 13 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Due to their promising microbicidal activity but their rather poor bioavailability and high toxicity, many analogues and derivatives, including pro-drugs, have been synthesized and screened in vitro and in vivo in order to improve their selectivity and pharmacological properties." | 2.49 | Novel amidines and analogues as promising agents against intracellular parasites: a systematic review. ( Boykin, DW; Hemphill, A; Soeiro, MN; Wang, MZ; Werbovetz, K; Wilson, WD, 2013) |
| "Pentamidine is an effective antimicrobial agent." | 1.33 | Diacetyldiamidoximeester of pentamidine, a prodrug for treatment of protozoal diseases: synthesis, in vitro and in vivo biotransformation. ( Bürenheide, A; Clement, B; Rieckert, W; Schwarz, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nava-Zuazo, C | 1 |
| Chávez-Silva, F | 1 |
| Moo-Puc, R | 2 |
| Chan-Bacab, MJ | 2 |
| Ortega-Morales, BO | 2 |
| Moreno-Díaz, H | 1 |
| Díaz-Coutiño, D | 1 |
| Hernández-Núñez, E | 2 |
| Navarrete-Vázquez, G | 2 |
| Colín-Lozano, B | 1 |
| León-Rivera, I | 1 |
| López-Guerrero, V | 1 |
| Argüello-Garcia, R | 1 |
| Scior, T | 1 |
| Barbosa-Cabrera, E | 1 |
| Soeiro, MN | 1 |
| Werbovetz, K | 1 |
| Boykin, DW | 1 |
| Wilson, WD | 1 |
| Wang, MZ | 1 |
| Hemphill, A | 1 |
| Clement, B | 1 |
| Bürenheide, A | 1 |
| Rieckert, W | 1 |
| Schwarz, J | 1 |
| Ajisawa, A | 1 |
| Sendino Revuelta, A | 1 |
| Barbado Hernández, FJ | 1 |
| Vázquez Rodríguez, JJ | 1 |
| Kern, P | 1 |
| Poblete, RB | 1 |
| Rodriguez, K | 1 |
| Foust, RT | 1 |
| Reddy, KR | 1 |
| Saldana, MJ | 1 |
| Hardy, WD | 1 |
| Northfelt, DW | 1 |
| Drake, TA | 1 |
| Lefrock, JL | 1 |
| Smith, BR | 1 |
| Pearson, RD | 1 |
| Hewlett, EL | 1 |
4 reviews available for pentamidine and Histomoniasis
| Article | Year |
|---|---|
Novel amidines and analogues as promising agents against intracellular parasites: a systematic review.
Topics: Amidines; Animals; Antiprotozoal Agents; Humans; Intracellular Space; Microscopy, Electron, Transmis | 2013 |
[The prevention of opportunistic infections in patients infected with the human immunodeficiency virus].
Topics: Acquired Immunodeficiency Syndrome; Bacterial Infections; HIV Infections; HIV-1; Humans; Mycoses; Op | 1990 |
[Use of pentamidine in protozoan diseases].
Topics: Humans; Leishmaniasis; Pentamidine; Pneumonia, Pneumocystis; Protozoan Infections; Trypanosomiasis, | 1990 |
Pentamidine for the treatment of Pneumocystis carinii pneumonia and other protozoal diseases.
Topics: Amidines; Humans; Leishmaniasis; Pentamidine; Pneumonia, Pneumocystis; Protozoan Infections; Trypano | 1985 |
9 other studies available for pentamidine and Histomoniasis
| Article | Year |
|---|---|
2-acylamino-5-nitro-1,3-thiazoles: preparation and in vitro bioevaluation against four neglected protozoan parasites.
Topics: Animals; Antiprotozoal Agents; Drug Design; Humans; Protozoan Infections; Thiazoles | 2014 |
Synthesis, in vitro and in vivo giardicidal activity of nitrothiazole-NSAID chimeras displaying broad antiprotozoal spectrum.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiprotozoal Agents; Drug Design; Female; Giardia | 2017 |
Diacetyldiamidoximeester of pentamidine, a prodrug for treatment of protozoal diseases: synthesis, in vitro and in vivo biotransformation.
Topics: Animals; Biotransformation; Esters; Humans; Magnetic Resonance Spectroscopy; Male; Oximes; Pentamidi | 2006 |
[Protozoan infections in AIDS].
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; AIDS-Related Opportunistic Infection | 1993 |
Pneumocystis carinii hepatitis in the acquired immunodeficiency syndrome (AIDS)
Topics: Acquired Immunodeficiency Syndrome; Adult; Animals; Hepatitis; Humans; Hypoproteinemia; Male; Pentam | 1989 |
Extrapulmonary Pneumocystis infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Amidines; Animals; Humans; Male; Pentamidine; P | 1989 |
Aerosolized pentamidine and disseminated infection with Pneumocystis carinii.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Amidines; Animals; Humans; Male; Pentamidine; P | 1989 |
Fatal, disseminated pneumocystosis in a patient with acquired immunodeficiency syndrome receiving prophylactic aerosolized pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Animals; Humans; Male; Pentamidine; Pneumocysti | 1989 |
Drugs for protozoan infections.
Topics: Antimalarials; Antimony Sodium Gluconate; Antiprotozoal Agents; Humans; Iodoquinol; Melarsoprol; Met | 1987 |