pentamidine has been researched along with Hematologic Malignancies in 4 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prophylaxis for Pneumocystis jirovecii pneumonia (PJP) is recommended for patients undergoing hematopoietic stem cell transplantation (HSCT) or intensive chemotherapy." | 2.87 | A prospective study of intravenous pentamidine for PJP prophylaxis in adult patients undergoing intensive chemotherapy or hematopoietic stem cell transplant. ( Anderson, J; Khan, I; Mactal-Haaf, C; Oh, A; Patel, P; Quigley, JG; Rondelli, D; Saraf, S; Sweiss, K; Wirth, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sweiss, K | 1 |
| Anderson, J | 1 |
| Wirth, S | 1 |
| Oh, A | 1 |
| Quigley, JG | 1 |
| Khan, I | 1 |
| Saraf, S | 1 |
| Mactal-Haaf, C | 1 |
| Rondelli, D | 1 |
| Patel, P | 1 |
| Quinn, M | 1 |
| Fannin, JT | 1 |
| Sciasci, J | 1 |
| Bragg, A | 1 |
| Campbell, PK | 1 |
| Carias, D | 1 |
| Crews, KR | 1 |
| Gregornik, D | 1 |
| Jeha, S | 1 |
| Maron, G | 1 |
| Pauley, JL | 1 |
| Swanson, HD | 1 |
| Wolf, J | 1 |
| Greene, W | 1 |
| Lim, MJ | 1 |
| Stebbings, A | 1 |
| Lim, SJ | 1 |
| Foor, K | 1 |
| Hou, JZ | 1 |
| Farah, R | 1 |
| Raptis, A | 1 |
| Marks, S | 1 |
| Weber, D | 1 |
| Im, A | 1 |
| Dorritie, K | 1 |
| Sehgal, A | 1 |
| Agha, M | 1 |
| Lim, SH | 1 |
| Vasconcelles, MJ | 1 |
| Bernardo, MV | 1 |
| King, C | 1 |
| Weller, EA | 1 |
| Antin, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment of the Safety and Intravenous Pentamidine for Pneumocystis Jirovecii Pneumonia in Patients With Hematologic Malignancies and Stem Cell Transplant Recipients.[NCT02669706] | 50 participants (Actual) | Observational | 2015-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for pentamidine and Hematologic Malignancies
| Article | Year |
|---|---|
A prospective study of intravenous pentamidine for PJP prophylaxis in adult patients undergoing intensive chemotherapy or hematopoietic stem cell transplant.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Drug Therapy; Hematologic Neoplasms; Hematopoi | 2018 |
Aerosolized pentamidine as pneumocystis prophylaxis after bone marrow transplantation is inferior to other regimens and is associated with decreased survival and an increased risk of other infections.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosol Propellants; Aged; Antifungal Agents; Bone Ma | 2000 |
2 other studies available for pentamidine and Hematologic Malignancies
| Article | Year |
|---|---|
Pentamidine for Prophylaxis against Pneumocystis jirovecii Pneumonia in Pediatric Oncology Patients Receiving Immunosuppressive Chemotherapy.
Topics: Administration, Intravenous; Aerosols; Antifungal Agents; Child, Preschool; Female; Hematologic Neop | 2018 |
IV pentamidine for primary PJP prophylaxis in adults undergoing allogeneic hematopoietic progenitor cell transplant.
Topics: Adult; Aged; Allografts; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Hum | 2015 |