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pentamidine and HIV

pentamidine has been researched along with HIV in 7 studies

Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.

Research Excerpts

ExcerptRelevanceReference
") 3 times per week, was evaluated in a double-blind, randomized, placebo-controlled trial of zidovudine (AZT)-treated asymptomatic human immunodeficiency virus (HIV)-infected subjects with 200-500 CD4 cells/mm3 at entry."9.08Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial. ( Beall, G; Blick, G; Calabrese, LH; Conant, MA; Fisher, A; Galpin, JE; Goldstein, G; Grossman, HA; Hirsch, RL; Stampone, P, 1995)
"In order to determine the possible effect of aerosolized pentamidine on the cellular composition of the bronchoalveolar lavage fluid in HIV-infected patients, differential counts of 22 consecutive patients who had been rebronchoscopied after 3-19 months were reviewed."7.68Pentamidine aerosol increases the number of alveolar macrophages in HIV-infected patients. ( Don, M; Eckert, G; Hilger, HH; Pothoff, G; Schell-Frederick, E; Wassermann, K, 1991)
") 3 times per week, was evaluated in a double-blind, randomized, placebo-controlled trial of zidovudine (AZT)-treated asymptomatic human immunodeficiency virus (HIV)-infected subjects with 200-500 CD4 cells/mm3 at entry."5.08Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial. ( Beall, G; Blick, G; Calabrese, LH; Conant, MA; Fisher, A; Galpin, JE; Goldstein, G; Grossman, HA; Hirsch, RL; Stampone, P, 1995)
"In order to determine the possible effect of aerosolized pentamidine on the cellular composition of the bronchoalveolar lavage fluid in HIV-infected patients, differential counts of 22 consecutive patients who had been rebronchoscopied after 3-19 months were reviewed."3.68Pentamidine aerosol increases the number of alveolar macrophages in HIV-infected patients. ( Don, M; Eckert, G; Hilger, HH; Pothoff, G; Schell-Frederick, E; Wassermann, K, 1991)
"Human African trypanosomiasis (HAT), otherwise known as sleeping sickness, has remained a disease with no effective treatment."2.42Arsenicals (melarsoprol), pentamidine and suramin in the treatment of human African trypanosomiasis. ( Nok, AJ, 2003)
"The diagnosis of acquired immunodeficiency syndrome (AIDS) was suspected, although enzyme-linked immunosorbent assay (ELISA) and Western blot tests were both negative for human immunodeficiency virus (HIV) antibody."1.27Pediatric acquired immunodeficiency syndrome with negative human immunodeficiency virus antibody response by enzyme-linked immunosorbent assay and Western blot. ( Goetz, DW; Hall, SE; Harbison, RW; Reid, MJ, 1988)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's3 (42.86)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vogt, F1
Mengesha, B1
Asmamaw, H1
Mekonnen, T1
Fikre, H1
Takele, Y1
Adem, E1
Mohammed, R1
Ritmeijer, K1
Adriaensen, W1
Melsew, Y1
van Griensven, J1
Diro, E1
O'Neal, CB1
Ball, SC1
Nok, AJ1
Goldstein, G1
Conant, MA1
Beall, G1
Grossman, HA1
Galpin, JE1
Blick, G1
Calabrese, LH1
Hirsch, RL1
Fisher, A1
Stampone, P1
Laguna, F1
Adrados, M1
Alvar, J1
Soriano, V1
Valencia, ME1
Moreno, V1
Polo, R1
Verdejo, J1
Jiménez, MI1
Martínez, P1
Martínez, ML1
González-Lahoz, JM1
Wassermann, K1
Schell-Frederick, E1
Eckert, G1
Don, M1
Pothoff, G1
Hilger, HH1
Goetz, DW1
Hall, SE1
Harbison, RW1
Reid, MJ1

Reviews

1 review available for pentamidine and HIV

ArticleYear
Arsenicals (melarsoprol), pentamidine and suramin in the treatment of human African trypanosomiasis.
    Parasitology research, 2003, Volume: 90, Issue:1

    Topics: Animals; Drug Resistance; HIV; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypa

2003

Trials

2 trials available for pentamidine and HIV

ArticleYear
Antigen Detection in Urine for Noninvasive Diagnosis and Treatment Monitoring of Visceral Leishmaniasis in Human Immunodeficiency Virus Coinfected Patients: An Exploratory Analysis from Ethiopia.
    The American journal of tropical medicine and hygiene, 2018, Volume: 99, Issue:4

    Topics: Adult; Antigens, Protozoan; Antiprotozoal Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphoc

2018
Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Mar-01, Volume: 8, Issue:3

    Topics: Adult; CD4 Lymphocyte Count; Disease Progression; Double-Blind Method; Drug Resistance, Microbial; D

1995

Other Studies

4 other studies available for pentamidine and HIV

ArticleYear
Splenic pneumocystosis: an atypical presentation of extrapulmonary Pneumocystis infection.
    The AIDS reader, 2008, Volume: 18, Issue:10

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antifungal Agents; Atovaquone; Female

2008
Visceral leishmaniasis in patients infected with the human immunodeficiency virus.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1997, Volume: 16, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Allopurinol; Amebicides; Amphotericin B; Analysis of Variance

1997
Pentamidine aerosol increases the number of alveolar macrophages in HIV-infected patients.
    AIDS (London, England), 1991, Volume: 5, Issue:9

    Topics: Administration, Inhalation; Adult; Aerosols; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cell Count;

1991
Pediatric acquired immunodeficiency syndrome with negative human immunodeficiency virus antibody response by enzyme-linked immunosorbent assay and Western blot.
    Pediatrics, 1988, Volume: 81, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Antibodies, Viral; Candidiasis; Enzyme-Linked Immunosorbent Assa

1988