pentamidine and HIV
pentamidine has been researched along with HIV in 7 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| ") 3 times per week, was evaluated in a double-blind, randomized, placebo-controlled trial of zidovudine (AZT)-treated asymptomatic human immunodeficiency virus (HIV)-infected subjects with 200-500 CD4 cells/mm3 at entry." | 9.08 | Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial. ( Beall, G; Blick, G; Calabrese, LH; Conant, MA; Fisher, A; Galpin, JE; Goldstein, G; Grossman, HA; Hirsch, RL; Stampone, P, 1995) |
| "In order to determine the possible effect of aerosolized pentamidine on the cellular composition of the bronchoalveolar lavage fluid in HIV-infected patients, differential counts of 22 consecutive patients who had been rebronchoscopied after 3-19 months were reviewed." | 7.68 | Pentamidine aerosol increases the number of alveolar macrophages in HIV-infected patients. ( Don, M; Eckert, G; Hilger, HH; Pothoff, G; Schell-Frederick, E; Wassermann, K, 1991) |
| ") 3 times per week, was evaluated in a double-blind, randomized, placebo-controlled trial of zidovudine (AZT)-treated asymptomatic human immunodeficiency virus (HIV)-infected subjects with 200-500 CD4 cells/mm3 at entry." | 5.08 | Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial. ( Beall, G; Blick, G; Calabrese, LH; Conant, MA; Fisher, A; Galpin, JE; Goldstein, G; Grossman, HA; Hirsch, RL; Stampone, P, 1995) |
| "In order to determine the possible effect of aerosolized pentamidine on the cellular composition of the bronchoalveolar lavage fluid in HIV-infected patients, differential counts of 22 consecutive patients who had been rebronchoscopied after 3-19 months were reviewed." | 3.68 | Pentamidine aerosol increases the number of alveolar macrophages in HIV-infected patients. ( Don, M; Eckert, G; Hilger, HH; Pothoff, G; Schell-Frederick, E; Wassermann, K, 1991) |
| "Human African trypanosomiasis (HAT), otherwise known as sleeping sickness, has remained a disease with no effective treatment." | 2.42 | Arsenicals (melarsoprol), pentamidine and suramin in the treatment of human African trypanosomiasis. ( Nok, AJ, 2003) |
| "The diagnosis of acquired immunodeficiency syndrome (AIDS) was suspected, although enzyme-linked immunosorbent assay (ELISA) and Western blot tests were both negative for human immunodeficiency virus (HIV) antibody." | 1.27 | Pediatric acquired immunodeficiency syndrome with negative human immunodeficiency virus antibody response by enzyme-linked immunosorbent assay and Western blot. ( Goetz, DW; Hall, SE; Harbison, RW; Reid, MJ, 1988) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Vogt, F | 1 |
| Mengesha, B | 1 |
| Asmamaw, H | 1 |
| Mekonnen, T | 1 |
| Fikre, H | 1 |
| Takele, Y | 1 |
| Adem, E | 1 |
| Mohammed, R | 1 |
| Ritmeijer, K | 1 |
| Adriaensen, W | 1 |
| Melsew, Y | 1 |
| van Griensven, J | 1 |
| Diro, E | 1 |
| O'Neal, CB | 1 |
| Ball, SC | 1 |
| Nok, AJ | 1 |
| Goldstein, G | 1 |
| Conant, MA | 1 |
| Beall, G | 1 |
| Grossman, HA | 1 |
| Galpin, JE | 1 |
| Blick, G | 1 |
| Calabrese, LH | 1 |
| Hirsch, RL | 1 |
| Fisher, A | 1 |
| Stampone, P | 1 |
| Laguna, F | 1 |
| Adrados, M | 1 |
| Alvar, J | 1 |
| Soriano, V | 1 |
| Valencia, ME | 1 |
| Moreno, V | 1 |
| Polo, R | 1 |
| Verdejo, J | 1 |
| Jiménez, MI | 1 |
| Martínez, P | 1 |
| Martínez, ML | 1 |
| González-Lahoz, JM | 1 |
| Wassermann, K | 1 |
| Schell-Frederick, E | 1 |
| Eckert, G | 1 |
| Don, M | 1 |
| Pothoff, G | 1 |
| Hilger, HH | 1 |
| Goetz, DW | 1 |
| Hall, SE | 1 |
| Harbison, RW | 1 |
| Reid, MJ | 1 |
Reviews
1 review available for pentamidine and HIV
| Article | Year |
|---|---|
Arsenicals (melarsoprol), pentamidine and suramin in the treatment of human African trypanosomiasis.
Topics: Animals; Drug Resistance; HIV; Humans; Melarsoprol; Pentamidine; Suramin; Trypanocidal Agents; Trypa | 2003 |
Trials
2 trials available for pentamidine and HIV
| Article | Year |
|---|---|
Antigen Detection in Urine for Noninvasive Diagnosis and Treatment Monitoring of Visceral Leishmaniasis in Human Immunodeficiency Virus Coinfected Patients: An Exploratory Analysis from Ethiopia.
Topics: Adult; Antigens, Protozoan; Antiprotozoal Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphoc | 2018 |
Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial.
Topics: Adult; CD4 Lymphocyte Count; Disease Progression; Double-Blind Method; Drug Resistance, Microbial; D | 1995 |
Other Studies
4 other studies available for pentamidine and HIV
| Article | Year |
|---|---|
Splenic pneumocystosis: an atypical presentation of extrapulmonary Pneumocystis infection.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antifungal Agents; Atovaquone; Female | 2008 |
Visceral leishmaniasis in patients infected with the human immunodeficiency virus.
Topics: AIDS-Related Opportunistic Infections; Allopurinol; Amebicides; Amphotericin B; Analysis of Variance | 1997 |
Pentamidine aerosol increases the number of alveolar macrophages in HIV-infected patients.
Topics: Administration, Inhalation; Adult; Aerosols; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cell Count; | 1991 |
Pediatric acquired immunodeficiency syndrome with negative human immunodeficiency virus antibody response by enzyme-linked immunosorbent assay and Western blot.
Topics: Acquired Immunodeficiency Syndrome; Antibodies, Viral; Candidiasis; Enzyme-Linked Immunosorbent Assa | 1988 |