pentamidine has been researched along with HIV Coinfection in 140 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| ") 3 times per week, was evaluated in a double-blind, randomized, placebo-controlled trial of zidovudine (AZT)-treated asymptomatic human immunodeficiency virus (HIV)-infected subjects with 200-500 CD4 cells/mm3 at entry." | 9.08 | Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial. ( Beall, G; Blick, G; Calabrese, LH; Conant, MA; Fisher, A; Galpin, JE; Goldstein, G; Grossman, HA; Hirsch, RL; Stampone, P, 1995) |
| "Open, nonrandomized, prospective evaluation of ventricular arrhythmia incidence in HIV-infected patients receiving pentamidine or trimethoprim-sulfamethoxazole (TMP-SMX) utilizing Holter monitoring prior to and during therapy with these agents." | 9.08 | A prospective study of the effect of I.V. pentamidine therapy on ventricular arrhythmias and QTc prolongation in HIV-infected patients. ( Costantino, T; Girgis, I; Gualberti, J; Langan, L; Malek, S; McGinn, TG; Mustaciuolo, V, 1997) |
| "There have been 15 published cases of probable pentamidine-induced torsade de pointes (TdP)." | 7.69 | Incidence of cardiac arrhythmias during intravenous pentamidine therapy in HIV-infected patients. ( Coyne, PE; Eisenhauer, MD; Eliasson, AH; Taylor, AJ; Wortham, DC, 1994) |
| "The incidence of Pneumocystis carinii pneumonia (PCP) and toxoplasmic encephalitis (TE) was analyzed in 83 human immunodeficiency virus (HIV)-infected patients who inhaled aerosolized pentamidine (AP) either for primary prophylaxis (group Ia) or secondary prophylaxis (group IIa) of PCP." | 7.68 | Prevention of Pneumocystis carinii pneumonia and toxoplasmic encephalitis in human immunodeficiency virus infected patients: a clinical approach comparing aerosolized pentamidine and pyrimethamine/sulfadoxine. ( Gottschalk, J; Grünewald, T; Jautzke, G; Köppen, S; Pohle, HD; Ruf, B, 1992) |
| "The incidences of pentamidine-associated nephrotoxicity and hyperkalemia were determined from a retrospective review of records in AIDS patients using standard definitions for both toxicities." | 7.68 | Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS. ( Bailie, GR; Briceland, LL, 1991) |
| "In order to determine the possible effect of aerosolized pentamidine on the cellular composition of the bronchoalveolar lavage fluid in HIV-infected patients, differential counts of 22 consecutive patients who had been rebronchoscopied after 3-19 months were reviewed." | 7.68 | Pentamidine aerosol increases the number of alveolar macrophages in HIV-infected patients. ( Don, M; Eckert, G; Hilger, HH; Pothoff, G; Schell-Frederick, E; Wassermann, K, 1991) |
| ") 3 times per week, was evaluated in a double-blind, randomized, placebo-controlled trial of zidovudine (AZT)-treated asymptomatic human immunodeficiency virus (HIV)-infected subjects with 200-500 CD4 cells/mm3 at entry." | 5.08 | Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial. ( Beall, G; Blick, G; Calabrese, LH; Conant, MA; Fisher, A; Galpin, JE; Goldstein, G; Grossman, HA; Hirsch, RL; Stampone, P, 1995) |
| "Open, nonrandomized, prospective evaluation of ventricular arrhythmia incidence in HIV-infected patients receiving pentamidine or trimethoprim-sulfamethoxazole (TMP-SMX) utilizing Holter monitoring prior to and during therapy with these agents." | 5.08 | A prospective study of the effect of I.V. pentamidine therapy on ventricular arrhythmias and QTc prolongation in HIV-infected patients. ( Costantino, T; Girgis, I; Gualberti, J; Langan, L; Malek, S; McGinn, TG; Mustaciuolo, V, 1997) |
| "In a meta-analysis, we examined the efficacy of aerosolized pentamidine, trimethoprim-sulfamethoxazole, and dapsone or dapsone/pyrimethamine for the prevention of Pneumocystis carinii pneumonia and toxoplasma encephalitis in patients with HIV infection." | 4.79 | Meta-analysis of prophylactic treatments against Pneumocystis carinii pneumonia and toxoplasma encephalitis in HIV-infected patients. ( Bucher, HC; Griffith, L; Guyatt, GH; Opravil, M, 1997) |
| " Cough-reduction measures should be taken when giving pentamidine aerosol, and patients who do cough should cover their mouths." | 4.78 | Control of tuberculosis during aerosol therapy administration. ( Chaisson, RE; McAvinue, S, 1991) |
| " Demographic information, family histories of diabetes mellitus, body weights, CD4+ lymphocyte counts, and use of corticosteroids, megestrol acetate, pentamidine, or didanosine were recorded for subjects meeting the case definition." | 3.70 | Severe hyperglycemia in an HIV clinic: preexisting versus drug-associated diabetes mellitus. ( Kilby, JM; Tabereaux, PB, 1998) |
| "There have been 15 published cases of probable pentamidine-induced torsade de pointes (TdP)." | 3.69 | Incidence of cardiac arrhythmias during intravenous pentamidine therapy in HIV-infected patients. ( Coyne, PE; Eisenhauer, MD; Eliasson, AH; Taylor, AJ; Wortham, DC, 1994) |
| "Clinical trials have shown that the prophylactic use of zidovudine and aerosolized pentamidine (or other antibiotics used as prophylaxis against Pneumocystis carinii pneumonia) in acquired immunodeficiency syndrome (AIDS)-free human immunodeficiency virus (HIV)-infected persons delays the development of AIDS, but the effectiveness of such therapy in general use in the population still remains largely undocumented." | 3.68 | Effect of routine use of therapy in slowing the clinical course of human immunodeficiency virus (HIV) infection in a population-based cohort. ( Clark, WS; Karon, JM; Longini, IM, 1993) |
| "From 1988 to 1991 the long-term efficacy of a combined therapy with a polyvalent immunoglobulin/cytomegalovirus (CMV) hyperimmunoglobulin, oral low dose zidovudine, oral cotrimoxazole or inhaled pentamidine was investigated in three groups of human immunodeficiency virus (HIV)-infected children." | 3.68 | Combined therapy in human immunodeficiency virus-infected children--a 4-year experience. ( Allendorf, A; Ehrenforth, S; Funk, M; Güngör, T; Hofmann, D; Kornhuber, B; Kreuz, W; Kynast, I; Linde, R; Lotz, C, 1993) |
| "The incidence of Pneumocystis carinii pneumonia (PCP) and toxoplasmic encephalitis (TE) was analyzed in 83 human immunodeficiency virus (HIV)-infected patients who inhaled aerosolized pentamidine (AP) either for primary prophylaxis (group Ia) or secondary prophylaxis (group IIa) of PCP." | 3.68 | Prevention of Pneumocystis carinii pneumonia and toxoplasmic encephalitis in human immunodeficiency virus infected patients: a clinical approach comparing aerosolized pentamidine and pyrimethamine/sulfadoxine. ( Gottschalk, J; Grünewald, T; Jautzke, G; Köppen, S; Pohle, HD; Ruf, B, 1992) |
| "The incidences of pentamidine-associated nephrotoxicity and hyperkalemia were determined from a retrospective review of records in AIDS patients using standard definitions for both toxicities." | 3.68 | Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS. ( Bailie, GR; Briceland, LL, 1991) |
| "In order to determine the possible effect of aerosolized pentamidine on the cellular composition of the bronchoalveolar lavage fluid in HIV-infected patients, differential counts of 22 consecutive patients who had been rebronchoscopied after 3-19 months were reviewed." | 3.68 | Pentamidine aerosol increases the number of alveolar macrophages in HIV-infected patients. ( Don, M; Eckert, G; Hilger, HH; Pothoff, G; Schell-Frederick, E; Wassermann, K, 1991) |
| "Nineteen episodes of cerebral toxoplasmosis were diagnosed during the study." | 2.67 | Trimethoprim-sulfamethoxazole versus aerosolized pentamidine for primary prophylaxis of Pneumocystis carinii pneumonia: a prospective, randomized, controlled clinical trial. LFPMI Study Group. Ligue Française de Prévention des Maladies Infectieuses. ( Beuscart, C; Borsa Lebas, F; Canton, P; Leclercq, P; Marchou, B; May, T; Micoud, M; Mouton, Y; Reynes, J; Saba, J, 1994) |
| "Standard therapy of pneumocystis carinii pneumonia with cotrimoxazole and intravenous pentamidine second line therapy both have a response rate of 75 to 90%." | 2.67 | [Comparison of the effect of 2 therapy concepts in the treatment of Pneumocystis carinii pneumonia. Cotrimoxazole for 21 days versus sequential therapy with cotrimoxazole followed by pentamidine inhalation]. ( Arasteh, K; Brodt, HR; Helm, EB; Jacobi, V; L'age, M; Mulert, R; Ottmann, O; Staszewski, S; Stille, W; Wegner, R, 1990) |
| " There is no significant difference in effect or safety between these two dosing regimens in patients followed for at least 52 weeks of therapy." | 2.67 | Aerosol pentamidine prophylaxis following Pneumocystis carinii pneumonia in AIDS patients: results of a blinded dose-comparison study using an ultrasonic nebulizer. ( Allan, JD; Boswell, SL; Davies, SF; Dupliss, R; Gordin, FM; Graziano, FM; Lavelle, JP; Murphy, RL; Saag, MS; Waskin, HA, 1991) |
| "40% in the TMP/SMX group)." | 2.67 | [Treatment of mild to moderately severe Pneumocystis carinii pneumonia with cotrimoxazole versus pentamidine aerosol. Preliminary results of a prospective randomized therapy study]. ( Arasteh, K; Heise, W; L'age, M, 1990) |
| "Patients with AIDS but without pneumocystis carinii pneumonia, patients with advanced AIDS-related complex (ARC), and asymptomatic patients with less than 200 CD4-positive lymphocytes/mm3 were randomized to one of two groups: group I: Inhalation of 300 mg of pentamidine every 28 days; group II: Inhalation of placebo (300 mg of Na isethionate) every 28 days." | 2.67 | Primary prevention of Pneumocystis carinii pneumonia by inhalation of pentamidine. Preliminary results from a placebo-controlled randomized trial. Swiss Group for Clinical Studies on AIDS. ( Chave, JP; Chopard, P; Furrer, HJ; Hilti, P; Hirschel, B; Lazzarin, A; Opravil, M; Vernazza, P, 1990) |
| "No proven pneumocystis carinii pneumonia was found in the observed patients." | 2.67 | [Preventive pentamidine inhalation of Pneumocystis carinii pneumonia in patients with immune deficiency. Preliminary evaluation of a multicenter study]. ( Bendick, C; Fätkenheuer, G; Rasokat, H; Salzberger, B; Schrappe-Bächer, M; Zehrer, I, 1990) |
| "The diagnosis of Pneumocystis carinii pneumonia (PCP) rests on the isolation of this micro-organism in patients whose latest blood count, less than 2 months old, shows less than 250 CD4 lymphocytes per cubic mm and who present with signs of impaired lung function." | 2.38 | [Pneumocystis carinii pneumonia in HIV infection. Diagnosis, prognostic factors and curative treatment]. ( Girard, PM; Saimot, AG, 1991) |
| "Although Pneumocystis carinii pneumonia (PCP) usually presents with bilateral interstitial pulmonary infiltrates, many other roentgenographic presentations occur in human immunodeficiency virus-infected patients." | 2.38 | Atypical roentgenographic manifestations of Pneumocystis carinii pneumonia. ( Goetz, MB; Kennedy, CA, 1992) |
| "Pneumocystis carinii pneumonia is the most common opportunistic infection in pregnancy." | 2.38 | [Pregnancy in HIV infected women. Current therapeutic indications]. ( Bongain, A; Fuzibet, JG; Gillet, JY; Pesce, A, 1992) |
| "Although Pneumocystis carinii pneumonia (PCP) can occur in any patient with severe impairment of immunity, there has been a sharp rise in incidence with the spread of human immunodeficiency virus through the USA and Western Europe, where nearly 80% of patients with HIV infection have at least one episode of PCP during their lifetime (Murray et al, 1984)." | 2.38 | Prophylaxis and treatment of Pneumocystis carinii pneumonia. ( Bateman, NT; O'Doherty, MJ, 1991) |
| "Pentamidine was completed after 3 weeks, and antiretroviral treatment (ART) was initiated with dolutegravir 50 mg and Descovy HT (emtricitabine [200 mg] and tenofovir alafenamide fumarate [25 mg])." | 1.72 | Extrapulmonary pneumocystosis in an antiretroviral therapy-naïve, HIV-positive patient. ( Hasegawa, M; Hashimoto, M; Hashimoto, N; Ito, Y; Osugi, Y; Yano, K, 2022) |
| " Although, the adverse events with reduced-dose PM were observed in 41 (54." | 1.56 | Safety and efficacy of reduced-dose pentamidine as second-line treatment for HIV-related pneumocystis pneumonia. ( Aoki, T; Gatanaga, H; Kikuchi, Y; Mutoh, Y; Oka, S; Teruya, K, 2020) |
| "Pneumothorax has been reported in several cases." | 1.37 | Fatal bilateral pneumothoraces following administration of aerosolised pentamidine. ( Green, A; Milne, N; Ong, BB, 2011) |
| "Kala-azar, or visceral leishmaniasis, is a hemoparasitic disease caused by Leishmania donovani." | 1.31 | Hepatitis B and C viral infections in Indian kala-azar patients receiving injectable anti-leishmanial drugs: a community-based study. ( Dwivedi, SN; Kumar, J; Singh, R, 2000) |
| " Dosing or frequency of TMP-SMX did not seem to influence risk of chemoprophylaxis failure." | 1.30 | Pneumocystis carinii pneumonia incidence and chemoprophylaxis failure in ambulatory HIV-infected patients. HIV Outpatient Study (HOPS) Investigators. ( Holmberg, SD; Moorman, AC; Palella, FJ; Von Bargen, JC, 1998) |
| "The bacteremias were not significantly associated with use of trimethoprim-sulfamethoxazole, quinolones, newer macrolides (azithromycin and clarithromycin), clindamycin or dapsone." | 1.30 | Prior antimicrobials and staphylococcal bacteremia in HIV-infected patients. ( Chaisson, RE; Moore, RD; Styrt, BA, 1997) |
| "We evaluated the effect of chronic Pneumocystis carinii pneumonia (PCP) prophylaxis, with a once a month dose of 300 mg of inhalatory pentamidine isethionate, on QT interval duration." | 1.30 | Inhalatory pentamidine therapy and the duration of the QT interval in HIV-infected patients. ( Cardoso, JS; Conde, C; Lecour, H; Mota-Miranda, A; Moura, B; Rocha-Gonçalves, F, 1997) |
| "We conclude that spontaneous pneumothorax is associated with poor prognosis in HIV infected patients." | 1.30 | [Spontaneous pneumothorax associated with human immunodeficiency virus (HIV) infection]. ( Cifrián Martínez, JM; Fernández Rozas, SM; García Pérez, MM; Golpe Gómez, R; Jiménez Gómez, A; Mons Lera, R, 1998) |
| "Pentamidine aerosols were administered at the hospital under medical supervision." | 1.29 | Long-term results of monthly inhaled pentamidine as primary prophylaxis of Pneumocystis carinii pneumonia in HIV-infected patients. ( Belguendouz, A; Deleuze, J; Gorin, I; Guillon, JM; Morini, JP; Pretet, S; Rousseau, F; Roux, ME; Salmon, D; Taki, BE, 1993) |
| " Pentamidine isethionate was administered intravenously over 60-90 minutes once a month, at a dosage of 4 mg/kg, in 250 mL of 5% dextrose in water." | 1.29 | Once-a-month administration of intravenous pentamidine to patients infected with human immunodeficiency virus as prophylaxis for Pneumocystis carinii pneumonia. ( Amador, C; Benito, C; Carbonell, C; Ena, J; Gutiérrez, F; Pasquau, F; Vilar, A, 1994) |
| " The infant's dose of pentamidine was based on an adult dosage of 300 to 600 mg/month, adjusted for minute ventilation and weight." | 1.29 | Aerosolized pentamidine for prophylaxis of Pneumocystis carinii pneumonia in infants with human immunodeficiency virus infection. ( Caspe, WB; Hand, IL; Lambert, G; Porricolo, M; Wiznia, AA, 1994) |
| " The mean time to first side effect was 12." | 1.29 | Crossover of human immunodeficiency virus-infected patients from aerosolized pentamidine to trimethoprim-sulfamethoxazole: lack of hematologic toxicity and relationship of side effects to CD4+ lymphocyte count. ( Anderson, MD; Kennedy, CA; Lewis, DE; Oldfield, EC; Pimentel, JA; Weiss, PJ, 1993) |
| "Occurrence or recurrence of PCP." | 1.29 | Predictors for failure of Pneumocystis carinii pneumonia prophylaxis. Multicenter AIDS Cohort Study. ( Hoover, DR; Kingsley, LA; Peng, Y; Phair, JP; Saah, AJ; Schrager, LK; Visscher, B, 1995) |
| "Bacteremia was caused by Staphylococcus aureus (23%), Pseudomonas aeruginosa (18%), Escherichia coli (16%), Streptococcus pneumoniae (14%) and others (31%)." | 1.29 | Community-acquired bacteremia in HIV-positive patients: protective benefit of co-trimoxazole. ( Edge, MD; Rimland, D, 1996) |
| "Effective prophylaxis exists against Pneumocystis carinii pneumonia, a major cause of illness and death among human immunodeficiency virus-infected children and adults." | 1.28 | Predicting risk of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected children. ( Rutstein, RM, 1991) |
| "The optimal dosage of pentamidine for prophylaxis of Pneumocystis carinii pneumonia (PcP) is unknown." | 1.28 | Low incidence of Pneumocystis carinii pneumonia in HIV patients receiving 300 mg pentamidine aerosol every 2 weeks. ( Bogner, JR; Goebel, FD; Kronawitter, U, 1992) |
| "None of the patients developed Pneumocystis carinii pneumonia during the limited protocol follow-up (mean, 9." | 1.28 | Aerosolized pentamidine: a well-tolerated mode of prophylaxis against Pneumocystis carinii pneumonia in older children with human immunodeficiency virus infection. ( Godwin, CR; Ognibene, FP; Orcutt, TA; Pizzo, PA, 1992) |
| "Pentamidine was analyzed in both phases of BAL fluid (supernatant and cell pellet) and in urine using high performance liquid chromatography." | 1.28 | Urine pentamidine as an indicator of lung pentamidine in patients receiving aerosol therapy. ( Morra, L; Smaldone, GC; Vinciguerra, C, 1991) |
| "The incidence of P carinii pneumonia did not correlate with any measured patient characteristic." | 1.28 | Deposition of aerosolized pentamidine and failure of pneumocystis prophylaxis. ( Dickinson, G; Marcial, E; Seymour, J; Smaldone, GC; Young, E, 1992) |
| "None of the patients developed pneumocystis carinii pneumonia." | 1.28 | [Preventive pentamidine inhalation in patients with HIV infection (CD3 and CD4) in ambulatory practice]. ( Baranowski, E, 1990) |
| "The case histories of 27 children with Pneumocystis carinii pneumonia (PCP) who were followed up in the AIDS Program at the Children's Hospital of New Jersey, Newark, are reviewed." | 1.28 | Clinical and laboratory correlates of Pneumocystis carinii pneumonia in children infected with HIV. ( Bagarazzi, M; Boland, M; Connor, E; Denny, T; Holland, B; McSherry, G; Oleske, J, 1991) |
| "A patient with a history of Pneumocystis carinii pneumonia (PCP) inhaled aerosolized pentamidine (AP) for secondary prophylaxis of PCP." | 1.28 | Upper lobe relapse of Pneumocystis carinii pneumonia during aerosolized pentamidine prophylaxis. ( Grünewald, T; Jautzke, G; Köppen, S; Ruf, B, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (2.86) | 18.7374 |
| 1990's | 115 (82.14) | 18.2507 |
| 2000's | 12 (8.57) | 29.6817 |
| 2010's | 6 (4.29) | 24.3611 |
| 2020's | 3 (2.14) | 2.80 |
| Authors | Studies |
|---|---|
| Chechi, F | 1 |
| Corsi, P | 1 |
| Bartolozzi, D | 1 |
| Gaiera, G | 1 |
| Bartoloni, A | 1 |
| Zammarchi, L | 1 |
| Hasegawa, M | 1 |
| Ito, Y | 1 |
| Osugi, Y | 1 |
| Hashimoto, M | 1 |
| Hashimoto, N | 1 |
| Yano, K | 1 |
| Mutoh, Y | 1 |
| Teruya, K | 1 |
| Aoki, T | 1 |
| Kikuchi, Y | 1 |
| Gatanaga, H | 1 |
| Oka, S | 1 |
| Diro, E | 3 |
| Ritmeijer, K | 3 |
| Boelaert, M | 1 |
| Alves, F | 2 |
| Mohammed, R | 2 |
| Abongomera, C | 2 |
| Ravinetto, R | 1 |
| De Crop, M | 1 |
| Fikre, H | 3 |
| Adera, C | 1 |
| van Loen, H | 1 |
| Tsoumanis, A | 1 |
| Adriaensen, W | 2 |
| Hailu, A | 2 |
| Griensven, JV | 1 |
| Vogt, F | 1 |
| Mengesha, B | 1 |
| Asmamaw, H | 1 |
| Mekonnen, T | 1 |
| Takele, Y | 1 |
| Adem, E | 1 |
| Melsew, Y | 1 |
| van Griensven, J | 2 |
| Edwards, T | 1 |
| Kibret, A | 1 |
| Bardonneau, C | 1 |
| Soipei, P | 1 |
| Mutinda, B | 1 |
| Omollo, R | 1 |
| Zijlstra, EE | 1 |
| Wasunna, M | 1 |
| Alvar, J | 1 |
| Alexander, N | 1 |
| Blesson, S | 1 |
| Boodman, C | 1 |
| Libman, M | 1 |
| Ndao, M | 1 |
| Yansouni, CP | 1 |
| Faucher, JF | 1 |
| Morquin, D | 1 |
| Reynes, J | 2 |
| Chirouze, C | 1 |
| Hoen, B | 1 |
| Le Moing, V | 1 |
| O'Neal, CB | 1 |
| Ball, SC | 1 |
| Padovese, V | 1 |
| Terranova, M | 1 |
| Toma, L | 1 |
| Barnabas, GA | 1 |
| Morrone, A | 1 |
| Green, A | 1 |
| Milne, N | 1 |
| Ong, BB | 1 |
| Kroll, CR | 1 |
| Gettes, LS | 1 |
| Obaji, J | 1 |
| Lee-Pack, LR | 2 |
| Gutierrez, C | 1 |
| Chan, CK | 3 |
| Bellamy, R | 3 |
| Kumarasamy, N | 1 |
| Vallabhaneni, S | 1 |
| Cecelia, AJ | 1 |
| Mayer, KH | 1 |
| Solomon, S | 1 |
| Carpenter, CC | 1 |
| Flanigan, TP | 1 |
| Manfredi, R | 1 |
| Marinacci, G | 1 |
| Calza, L | 1 |
| Passarini, B | 1 |
| Uzzan, B | 1 |
| Bentata, M | 1 |
| Campos, J | 1 |
| Mosnier, A | 1 |
| Krivitzky, A | 1 |
| Perret, GY | 1 |
| Modigliani, E | 1 |
| Hoernle, EH | 1 |
| Reid, TE | 1 |
| Saah, AJ | 1 |
| Hoover, DR | 1 |
| Peng, Y | 1 |
| Phair, JP | 1 |
| Visscher, B | 1 |
| Kingsley, LA | 1 |
| Schrager, LK | 1 |
| Opravil, M | 3 |
| Pechère, M | 1 |
| Lazzarin, A | 2 |
| Heald, A | 1 |
| Rüttimann, S | 1 |
| Iten, A | 1 |
| Furrer, H | 1 |
| Oertle, D | 1 |
| Praz, G | 1 |
| Vuitton, DA | 1 |
| Singh, G | 1 |
| el-Gadi, SM | 1 |
| Sparks, RA | 1 |
| Brivet, FG | 1 |
| Naveau, SH | 1 |
| Lemaigre, GF | 1 |
| Dormont, J | 1 |
| Domingo, P | 1 |
| Ris, J | 1 |
| Serra, J | 1 |
| Puig, M | 1 |
| Martinez, E | 1 |
| Sambeat, MA | 1 |
| Sabin, C | 1 |
| Pasi, J | 1 |
| Phillips, A | 1 |
| Elford, J | 1 |
| Janossy, G | 1 |
| Lee, C | 1 |
| Goldstein, G | 1 |
| Conant, MA | 1 |
| Beall, G | 1 |
| Grossman, HA | 1 |
| Galpin, JE | 1 |
| Blick, G | 1 |
| Calabrese, LH | 1 |
| Hirsch, RL | 1 |
| Fisher, A | 1 |
| Stampone, P | 1 |
| Veyssier, P | 1 |
| Cevallos, R | 1 |
| Le Fouillé-Ribeyre, C | 1 |
| Geffray, L | 1 |
| Kaloustian, E | 1 |
| Farinotti, R | 1 |
| Jablonowski, H | 1 |
| Sander, O | 1 |
| Willers, R | 1 |
| Adams, O | 1 |
| Bartmann, P | 1 |
| Wahn, V | 1 |
| Luchon, L | 1 |
| Couderc, LJ | 1 |
| Stern, M | 1 |
| Friard, S | 1 |
| Caubarrere, I | 1 |
| Nolan, A | 1 |
| Lamey, PJ | 1 |
| MacFarlane, TW | 1 |
| Aitchison, TC | 1 |
| Shaw, J | 1 |
| Sirel, JY | 1 |
| Ena, J | 1 |
| Amador, C | 1 |
| Pasquau, F | 1 |
| Carbonell, C | 1 |
| Benito, C | 1 |
| Gutiérrez, F | 1 |
| Vilar, A | 1 |
| Longini, IM | 1 |
| Clark, WS | 1 |
| Karon, JM | 1 |
| Kennedy, CA | 2 |
| Pimentel, JA | 1 |
| Lewis, DE | 1 |
| Anderson, MD | 1 |
| Weiss, PJ | 1 |
| Oldfield, EC | 1 |
| Güngör, T | 2 |
| Funk, M | 2 |
| Linde, R | 2 |
| Kynast, I | 1 |
| Allendorf, A | 1 |
| Lotz, C | 2 |
| Ehrenforth, S | 2 |
| Hofmann, D | 1 |
| Kornhuber, B | 2 |
| Kreuz, W | 2 |
| May, T | 1 |
| Beuscart, C | 1 |
| Marchou, B | 1 |
| Leclercq, P | 1 |
| Borsa Lebas, F | 1 |
| Saba, J | 1 |
| Micoud, M | 1 |
| Mouton, Y | 1 |
| Canton, P | 1 |
| Hand, IL | 1 |
| Wiznia, AA | 1 |
| Porricolo, M | 1 |
| Lambert, G | 1 |
| Caspe, WB | 1 |
| Mayer, HB | 1 |
| Rose, DN | 1 |
| Cohen, S | 1 |
| Gurtman, AC | 1 |
| Cheung, TW | 1 |
| Szabo, S | 1 |
| O'Riordan, TG | 2 |
| Smaldone, GC | 5 |
| Eisenhauer, MD | 1 |
| Eliasson, AH | 1 |
| Taylor, AJ | 1 |
| Coyne, PE | 1 |
| Wortham, DC | 1 |
| Ewig, S | 2 |
| Rockstroh, JK | 1 |
| Christ, F | 1 |
| Lang, W | 1 |
| Osmond, D | 1 |
| Page-Bodkin, K | 1 |
| Moss, A | 1 |
| Winkelstein, W | 1 |
| Pretet, S | 1 |
| Salmon, D | 1 |
| Rousseau, F | 1 |
| Guillon, JM | 1 |
| Taki, BE | 1 |
| Roux, ME | 1 |
| Belguendouz, A | 1 |
| Deleuze, J | 1 |
| Morini, JP | 1 |
| Gorin, I | 1 |
| Dupon, M | 1 |
| Malou, M | 1 |
| Rogues, AM | 1 |
| Lacut, JY | 1 |
| Mallolas, J | 2 |
| Zamora, L | 1 |
| Gatell, JM | 1 |
| Miró, JM | 2 |
| Vernet, E | 1 |
| Valls, ME | 1 |
| Soriano, E | 1 |
| SanMiguel, JG | 1 |
| Gaur, S | 1 |
| Rosenthal, S | 1 |
| Dadhania, J | 1 |
| Lupski, D | 1 |
| Mascarhenas, M | 1 |
| Amenta, PS | 1 |
| Bharucha, N | 1 |
| Cappell, MS | 1 |
| Girard, PM | 4 |
| Landman, R | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Secondary Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients Using Pentamidine as a Prophylactic Agent: a Prospective Cohort Study[NCT01360762] | Phase 3 | 74 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| A Randomized Trial of Ambisome Monotherapy and Combination of Ambisome and Miltefosine for the Treatment of VL in HIV Positive Patients in Ethiopia Followed by Secondary VL Prophylactic Treatment With Pentamidine.[NCT02011958] | Phase 3 | 59 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| A Randomized, Open-Label Trial of High Dose Atovaquone Versus Low Dose Atovaquone Versus Aerosolized Pentamidine for Prophylaxis of Pneumocystis Carinii Pneumonia in Patients With HIV Infection Who Are Intolerant of TMP/SMX[NCT00002340] | Phase 3 | 615 participants | Interventional | Completed | |||
| Aerosols in the Treatment of Pneumocystis Pneumonia: A Pilot Study Quantitating the Deposition of Aerosolized Pentamidine as Delivered in ACTG 040 and Comparing Its Toxicity With Parenteral Pentamidine Therapy[NCT00000722] | 45 participants | Interventional | Completed | ||||
| Aerosols in the Treatment of Pneumocystis Carinii Pneumonia: A Nested Study Quantitating the Delivery of Aerosolized Pentamidine for Prophylaxis of PCP in Protocols ACTG 021 and ACTG 081[NCT00001003] | 20 participants | Interventional | Completed | ||||
| Aerosols in the Treatment of Asymptomatic Pneumocystis Pneumonia: A Pilot Study Assessing the Effectiveness of Aerosolized Pentamidine as Treatment of Subclinical Pneumocystis Infection in Patients With No Clinical Symptoms[NCT00000707] | 20 participants | Interventional | Completed | ||||
| A Double-Blind Group Comparative Study To Evaluate the Long-Term Safety and Effectiveness of Two Different Doses of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients With Multiple Episodes of PCP[NCT00002055] | 0 participants | Interventional | Completed | ||||
| A Double-Blind Group Comparative Study To Evaluate the Safety and Effectiveness of Three Different Doses of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in Patients With AIDS Post First Episode PCP[NCT00002291] | 0 participants | Interventional | Completed | ||||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of patients with SAEs which are possibly, probably or definitely drug-related following clinician's assessment or that lead to permanent drug discontinuations during the first year of pentamidine administration (NCT01360762)
Timeframe: 1 year
| Intervention | Participants (Count of Participants) |
|---|---|
| Pentamidine Secondary Prophylaxis (PSP) | 3 |
During the first year of pentamidine administration for prophylaxis: participants with any drug-related non-serious adverse events (with drug-related defined as possibly, probably or definitely related to primary therapy following physicians assessment) as well as any serious adverse events (drug-related or not) (NCT01360762)
Timeframe: 1 year
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Drug-related non-serious adverse events | Any serious adverse event | |
| Pentamidine Secondary Prophylaxis (PSP) | 30 | 17 |
The number of required additional clinical interventions/therapeutic procedures (NCT01360762)
Timeframe: 30 months
| Intervention | number of events (Number) | |||
|---|---|---|---|---|
| Additional IV fluid during PM administration | Prolonged hospital observation | additional medication during PM infusion | Additional IV or oral glucose | |
| Pentamidine Secondary Prophylaxis (PSP) | 10 | 2 | 2 | 1 |
Number of treatment discontinuations and interruptions/missed doses. (NCT01360762)
Timeframe: 30 months
| Intervention | number of events (Number) | ||
|---|---|---|---|
| Permanent discontinuation | Missed more than 1 dose | Treatment interruption | |
| Pentamidine Secondary Prophylaxis (PSP) | 2 | 4 | 0 |
Probability of relapse-free survival up to one year after the start of the intervention (PSP) (at month 6 and month 12) (NCT01360762)
Timeframe: up to 1 year after the start of the intervention (PSP)
| Intervention | percentage probability (Number) | |
|---|---|---|
| Probability of relapse-free survival at 6 months | Probability of relapse-free survival at 12 months | |
| Pentamidine Secondary Prophylaxis (PSP) | 79 | 71 |
19 reviews available for pentamidine and HIV Coinfection
| Article | Year |
|---|---|
Pneumocystis carinii pneumonia treatment in people infected with HIV.
Topics: Antifungal Agents; Atovaquone; Clindamycin; Dapsone; Drug Therapy, Combination; HIV Infections; Huma | 2004 |
Pneumocystis pneumonia in people with HIV.
Topics: Atovaquone; Clindamycin; Corticosterone; Dapsone; Drug Therapy, Combination; HIV Infections; Humans; | 2005 |
Pneumocystis pneumonia in people with HIV.
Topics: Anti-Infective Agents; Antiprotozoal Agents; Atovaquone; Clindamycin; Dapsone; Drug Therapy, Combina | 2006 |
Human immunodeficiency virus infection in children.
Topics: Adolescent; AIDS-Related Opportunistic Infections; Child; Child, Preschool; Dapsone; Didanosine; Dru | 1995 |
Pancreatic lesions in HIV-infected patients.
Topics: Acute Disease; AIDS-Related Opportunistic Infections; Didanosine; HIV Infections; Humans; Pancreas; | 1994 |
The use of intravenous immunoglobulins in symptomatic HIV infection. Results of a randomized study.
Topics: AIDS-Related Opportunistic Infections; CD4-Positive T-Lymphocytes; Combined Modality Therapy; HIV In | 1994 |
Recommendations for prophylaxis against Pneumocystis carinii pneumonia for persons infected with human immunodeficiency virus. U.S. Public Health Service Task Force on Antipneumocystis Prophylaxis in Patients with Human Immunodeficiency Virus Infection.
Topics: AIDS-Related Opportunistic Infections; Clinical Trials as Topic; HIV Infections; Humans; Pentamidine | 1993 |
Meta-analysis of prophylactic treatments against Pneumocystis carinii pneumonia and toxoplasma encephalitis in HIV-infected patients.
Topics: Administration, Inhalation; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal | 1997 |
Control of tuberculosis during aerosol therapy administration.
Topics: Aerosols; Cough; Cross Infection; HIV Infections; Humans; Nebulizers and Vaporizers; Pentamidine; Pe | 1991 |
Prophylaxis for Pneumocystis carinii pneumonia in patients infected with human immunodeficiency virus.
Topics: Administration, Inhalation; Aerosols; CD4-Positive T-Lymphocytes; HIV Infections; Humans; Leukocyte | 1992 |
Gastrointestinal pneumocystosis in HIV-infected patients on aerosolized pentamidine: report of five cases and literature review.
Topics: Adult; Aerosols; Gastrointestinal Diseases; HIV Infections; Humans; Male; Middle Aged; Pentamidine; | 1992 |
[Pregnancy in HIV infected women. Current therapeutic indications].
Topics: Abortion, Therapeutic; Adult; CD4 Immunoadhesins; Female; HIV Infections; Humans; Immunization, Pass | 1992 |
Atypical roentgenographic manifestations of Pneumocystis carinii pneumonia.
Topics: HIV Infections; Humans; Pentamidine; Pneumonia, Pneumocystis; Radiography | 1992 |
[Pneumocystis carinii pneumonia in HIV infection. Diagnosis, prognostic factors and curative treatment].
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; CD4-Positive T-Lymphocytes; Dapsone; Eflornithine; F | 1991 |
Prophylaxis and treatment of Pneumocystis carinii pneumonia.
Topics: Antimalarials; CD4-Positive T-Lymphocytes; Clinical Protocols; Dapsone; Drug Combinations; HIV Infec | 1991 |
[Pneumocystis carinii pneumonia in HIV infections. Committee of the 1st Consensus Conference of anti-infectious therapy organized in May 1990 in Paris by the Société de Pathologie Infectieuse de Langue Française].
Topics: Acquired Immunodeficiency Syndrome; Aerosols; Clinical Protocols; Dapsone; France; HIV Infections; H | 1990 |
[Drug surveillance for adverse reactions in patients with human immunodeficiency virus infection].
Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Antitubercular Agents; Drug-Related Side Effects | 1990 |
[The prevention of opportunistic infections in patients infected with the human immunodeficiency virus].
Topics: Acquired Immunodeficiency Syndrome; Bacterial Infections; HIV Infections; HIV-1; Humans; Mycoses; Op | 1990 |
[Consensus conference: pneumocystosis in HIV infections. 1st consensus conference in anti-infection therapeutics organized by "la Société de Pathologie Infectieuse de langue française", May 11, 1990].
Topics: Adrenal Cortex Hormones; Dapsone; France; HIV Infections; Humans; Opportunistic Infections; Pentamid | 1990 |
27 trials available for pentamidine and HIV Coinfection
| Article | Year |
|---|---|
Long-term Clinical Outcomes in Visceral Leishmaniasis/Human Immunodeficiency Virus-Coinfected Patients During and After Pentamidine Secondary Prophylaxis in Ethiopia: A Single-Arm Clinical Trial.
Topics: Adult; Antiprotozoal Agents; Coinfection; Ethiopia; Female; HIV Infections; Humans; Leishmaniasis, V | 2018 |
Antigen Detection in Urine for Noninvasive Diagnosis and Treatment Monitoring of Visceral Leishmaniasis in Human Immunodeficiency Virus Coinfected Patients: An Exploratory Analysis from Ethiopia.
Topics: Adult; Antigens, Protozoan; Antiprotozoal Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphoc | 2018 |
Effects of aerosolized pentamidine on glucose homeostasis and insulin secretion in HIV-positive patients: a controlled study.
Topics: Administration, Inhalation; Adult; Aerosols; AIDS-Related Opportunistic Infections; C-Peptide; Cross | 1995 |
Dapsone/pyrimethamine may prevent mycobacterial disease in immunosuppressed patients infected with the human immunodeficiency virus.
Topics: Adult; CD4 Lymphocyte Count; Dapsone; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Huma | 1995 |
Aerosolized pentamidine prophylaxis of Pneumocystis carinii pneumonia in HIV-infected patients.
Topics: Adult; Aerosols; Aged; Female; HIV Infections; Humans; Male; Middle Aged; Pentamidine; Pneumonia, Pn | 1995 |
Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial.
Topics: Adult; CD4 Lymphocyte Count; Disease Progression; Double-Blind Method; Drug Resistance, Microbial; D | 1995 |
The use of intravenous immunoglobulins in symptomatic HIV infection. Results of a randomized study.
Topics: AIDS-Related Opportunistic Infections; CD4-Positive T-Lymphocytes; Combined Modality Therapy; HIV In | 1994 |
The effect of nebulised pentamidine on the concentration of intra-oral Candida albicans in HIV-infected patients.
Topics: Administration, Inhalation; Adult; Aerosols; Candida albicans; Candidiasis, Oral; Carrier State; Fem | 1994 |
Trimethoprim-sulfamethoxazole versus aerosolized pentamidine for primary prophylaxis of Pneumocystis carinii pneumonia: a prospective, randomized, controlled clinical trial. LFPMI Study Group. Ligue Française de Prévention des Maladies Infectieuses.
Topics: Adult; Aerosols; AIDS-Related Opportunistic Infections; Female; Follow-Up Studies; HIV Infections; H | 1994 |
Primary prophylaxis for Pneumocystis carinii pneumonia: a randomized trial comparing cotrimoxazole, aerosolized pentamidine and dapsone plus pyrimethamine.
Topics: Adult; Aerosols; AIDS-Related Opportunistic Infections; Antifungal Agents; Dapsone; Drug Therapy, Co | 1993 |
Dapsone-pyrimethamine compared with aerosolized pentamidine as primary prophylaxis against Pneumocystis carinii pneumonia and toxoplasmosis in HIV infection. The PRIO Study Group.
Topics: Adult; AIDS-Related Complex; AIDS-Related Opportunistic Infections; Dapsone; Drug Combinations; Ence | 1993 |
A prospective study of the effect of I.V. pentamidine therapy on ventricular arrhythmias and QTc prolongation in HIV-infected patients.
Topics: Adult; Anti-Infective Agents; Arrhythmias, Cardiac; Echocardiography; Echocardiography, Doppler; Ele | 1997 |
Prophylaxis for opportunistic infections among HIV-infected patients receiving medical care.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Analysis of Variance; Anti-Infective Agent | 1998 |
Acute pulmonary effects of three nebulizers for administering aerosol pentamidine: comparison of Parineb to Fisoneb and Respirgard II.
Topics: Administration, Inhalation; Analysis of Variance; Antifungal Agents; Bronchial Spasm; Cross-Over Stu | 1996 |
Atovaquone suspension compared with aerosolized pentamidine for prevention of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected subjects intolerant of trimethoprim or sulfonamides.
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Agents; Atovaq | 1999 |
Discontinuation of primary prophylaxis for Pneumocystis carinii pneumonia and toxoplasmic encephalitis in human immunodeficiency virus type I-infected patients: the changes in opportunistic prophylaxis study.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS-Related Opportunistic Infections; Anti-HIV Age | 2000 |
Aerosol pentamidine-induced bronchoconstriction. Predictive factors and preventive therapy.
Topics: Adult; Aerosols; Albuterol; Bronchial Provocation Tests; Bronchoconstriction; Bronchodilator Agents; | 1991 |
First experience with pentamidine inhalation in human immunodeficiency virus-infected children.
Topics: Administration, Inhalation; Adolescent; Child; Child, Preschool; HIV Infections; Humans; Pentamidine | 1991 |
Aerosolized pentamidine for prophylaxis against Pneumocystis carinii pneumonia. The San Francisco community prophylaxis trial.
Topics: Adult; Aerosols; CD4-Positive T-Lymphocytes; Drug Administration Schedule; Drug Evaluation; Female; | 1990 |
Aerosol pentamidine prophylaxis following Pneumocystis carinii pneumonia in AIDS patients: results of a blinded dose-comparison study using an ultrasonic nebulizer.
Topics: Adult; Aerosols; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; HIV Inf | 1991 |
Aerosol pentamidine prophylaxis following Pneumocystis carinii pneumonia in AIDS patients: results of a blinded dose-comparison study using an ultrasonic nebulizer.
Topics: Adult; Aerosols; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; HIV Inf | 1991 |
Aerosol pentamidine prophylaxis following Pneumocystis carinii pneumonia in AIDS patients: results of a blinded dose-comparison study using an ultrasonic nebulizer.
Topics: Adult; Aerosols; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; HIV Inf | 1991 |
Aerosol pentamidine prophylaxis following Pneumocystis carinii pneumonia in AIDS patients: results of a blinded dose-comparison study using an ultrasonic nebulizer.
Topics: Adult; Aerosols; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; HIV Inf | 1991 |
Diagnostic and therapeutic technology assessment. Prophylactic treatment for opportunistic infections in HIV-positive patients: aerosolized pentamidine.
Topics: American Medical Association; Clinical Trials as Topic; HIV Infections; Humans; Nebulizers and Vapor | 1990 |
[Lung deposition of 300 and 600 mg pentamidine, inhaled with 3 different inhalers].
Topics: Aerosols; Double-Blind Method; HIV Infections; Humans; Lung; Nebulizers and Vaporizers; Opportunisti | 1990 |
[Therapy of HIV associated mild and moderately severe Pneumocystis carinii pneumonia with 600 mg/die pentamidine aerosol. Results of a multicenter study].
Topics: Administration, Inhalation; Adult; Aerosols; HIV Infections; Humans; Multicenter Studies as Topic; O | 1990 |
[Treatment of mild to moderately severe Pneumocystis carinii pneumonia with cotrimoxazole versus pentamidine aerosol. Preliminary results of a prospective randomized therapy study].
Topics: Administration, Inhalation; Adult; HIV Infections; Humans; Infusions, Intravenous; Male; Opportunist | 1990 |
Primary prevention of Pneumocystis carinii pneumonia by inhalation of pentamidine. Preliminary results from a placebo-controlled randomized trial. Swiss Group for Clinical Studies on AIDS.
Topics: Administration, Inhalation; HIV Infections; Humans; Opportunistic Infections; Pentamidine; Pneumonia | 1990 |
[Preventive pentamidine inhalation of Pneumocystis carinii pneumonia in patients with immune deficiency. Preliminary evaluation of a multicenter study].
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Aged; Female; HIV Infections; | 1990 |
[Comparison of the effect of 2 therapy concepts in the treatment of Pneumocystis carinii pneumonia. Cotrimoxazole for 21 days versus sequential therapy with cotrimoxazole followed by pentamidine inhalation].
Topics: Administration, Inhalation; Adult; Drug Administration Schedule; Drug Therapy, Combination; Female; | 1990 |
95 other studies available for pentamidine and HIV Coinfection
| Article | Year |
|---|---|
Case Report: Intravenous Pentamidine Rescue Treatment for Active Chronic Visceral Leishmaniasis in an HIV-1 Infected Patient.
Topics: Administration, Intravenous; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Coinfectio | 2021 |
Extrapulmonary pneumocystosis in an antiretroviral therapy-naïve, HIV-positive patient.
Topics: HIV Infections; HIV Seropositivity; Humans; Male; Pentamidine; Pneumocystis carinii; Pneumonia, Pneu | 2022 |
Safety and efficacy of reduced-dose pentamidine as second-line treatment for HIV-related pneumocystis pneumonia.
Topics: HIV Infections; Humans; Pentamidine; Pneumocystis; Pneumonia, Pneumocystis; Retrospective Studies | 2020 |
Long term outcomes and prognostics of visceral leishmaniasis in HIV infected patients with use of pentamidine as secondary prophylaxis based on CD4 level: a prospective cohort study in Ethiopia.
Topics: Adult; Antiprotozoal Agents; CD4 Lymphocyte Count; Cohort Studies; Coinfection; Ethiopia; Female; HI | 2019 |
Case Report:
Topics: Coinfection; Congo; Female; Fever; HIV Infections; HIV-1; Humans; Middle Aged; Multiple Myeloma; Pen | 2019 |
Serial use of pentamidine and miltefosine for treating Leishmania infantum-HIV coinfection.
Topics: Antiprotozoal Agents; Coinfection; HIV Infections; Humans; Immunocompromised Host; Leishmania infant | 2016 |
Splenic pneumocystosis: an atypical presentation of extrapulmonary Pneumocystis infection.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antifungal Agents; Atovaquone; Female | 2008 |
Cutaneous and mucocutaneous leishmaniasis in Tigray, northern Ethiopia: clinical aspects and therapeutic concerns.
Topics: Adolescent; Adult; Antiprotozoal Agents; Child; Child, Preschool; Ethiopia; Female; HIV Infections; | 2009 |
Fatal bilateral pneumothoraces following administration of aerosolised pentamidine.
Topics: Administration, Inhalation; AIDS-Related Opportunistic Infections; Antifungal Agents; Asthma; Forens | 2011 |
T wave alternans and Torsades de Pointes after the use of intravenous pentamidine.
Topics: Antiprotozoal Agents; Electrocardiography; Female; HIV Infections; Humans; Infusions, Intravenous; M | 2002 |
The pulmonary effects of long-term exposure to aerosol pentamidine: a 5-year surveillance study in HIV-infected patients.
Topics: Administration, Inhalation; Adult; Antiprotozoal Agents; Drug Tolerance; Follow-Up Studies; Forced E | 2003 |
Safe discontinuation of primary pneumocystis prophylaxis in Southern Indian HIV-infected patients on highly active antiretroviral therapy.
Topics: Anti-Infective Agents; Anti-Retroviral Agents; Antiprotozoal Agents; Antiretroviral Therapy, Highly | 2005 |
Diffuse cutaneous dissemination of visceral leishmaniasis during human immunodeficiency virus (HIV) infection, despite negligible immunodeficiency: repeated failure of liposomal amphotericin B administration, followed by successful long-term pentamidine a
Topics: Adult; Amphotericin B; Antiprotozoal Agents; Drug Carriers; HIV Infections; Humans; Leishmaniasis, V | 2008 |
Predictors for failure of Pneumocystis carinii pneumonia prophylaxis. Multicenter AIDS Cohort Study.
Topics: Adult; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Dapsone; HIV Infections; HIV-1; | 1995 |
Pancreatitis associated with aerosolised pentamidine.
Topics: Acute Disease; Adult; Aerosols; HIV Infections; Humans; Male; Pancreatitis; Pentamidine; Pneumonia, | 1995 |
CD4+ counts before and after switching to monoclonal high-purity factor VIII concentrate in HIV-infected haemophilic patients.
Topics: Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Child; Child, | 1994 |
Safety of pentamidine prophylaxis for Pneumocystis carinii pneumonia on the endocrine pancreatic function in HIV patients.
Topics: Adult; Aerosols; AIDS-Related Opportunistic Infections; HIV Infections; HIV Seropositivity; Humans; | 1994 |
[Pulmonary pneumocystosis revealing HIV infection].
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Female; HIV Infect | 1994 |
Once-a-month administration of intravenous pentamidine to patients infected with human immunodeficiency virus as prophylaxis for Pneumocystis carinii pneumonia.
Topics: Adult; Aged; Drug Administration Schedule; HIV Infections; Humans; Injections, Intravenous; Male; Mi | 1994 |
Effect of routine use of therapy in slowing the clinical course of human immunodeficiency virus (HIV) infection in a population-based cohort.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; CD4-Positive T-Lymphocyte | 1993 |
Crossover of human immunodeficiency virus-infected patients from aerosolized pentamidine to trimethoprim-sulfamethoxazole: lack of hematologic toxicity and relationship of side effects to CD4+ lymphocyte count.
Topics: Adult; Aerosols; Aged; CD4-Positive T-Lymphocytes; Drug Combinations; Female; HIV Infections; Humans | 1993 |
Combined therapy in human immunodeficiency virus-infected children--a 4-year experience.
Topics: CD4-Positive T-Lymphocytes; Child; Child, Preschool; Cytomegalovirus; Drug Therapy, Combination; HIV | 1993 |
Aerosolized pentamidine for prophylaxis of Pneumocystis carinii pneumonia in infants with human immunodeficiency virus infection.
Topics: Aerosols; AIDS-Related Opportunistic Infections; HIV Infections; Humans; Infant; Pentamidine; Pneumo | 1994 |
The effect of Pneumocystis carinii pneumonia prophylaxis regimens on the incidence of bacterial infections in HIV-infected patients.
Topics: Adult; AIDS-Related Opportunistic Infections; Bacterial Infections; Cohort Studies; Female; HIV Infe | 1993 |
Regional deposition and regional ventilation during inhalation of pentamidine.
Topics: Administration, Inhalation; Aerosols; Albuterol; Forced Expiratory Volume; HIV Infections; Humans; K | 1994 |
Incidence of cardiac arrhythmias during intravenous pentamidine therapy in HIV-infected patients.
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Arrhythmias, Cardiac; Cohort Studies; Dose-Respo | 1994 |
Pneumocystis carinii pneumonia presenting as an upper lobe cavity after aerosolized pentamidine prophylaxis in an HIV-infected patient.
Topics: Adult; Aerosols; Hemophilia A; HIV Infections; Humans; Pentamidine; Pneumonia, Pneumocystis; Radiogr | 1993 |
Population-based estimates of antiretroviral therapy and anti-Pneumocystis prophylaxis in San Francisco: 1991.
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antiviral Agents; Cohort Studies; Daps | 1993 |
Long-term results of monthly inhaled pentamidine as primary prophylaxis of Pneumocystis carinii pneumonia in HIV-infected patients.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Drug Administration Schedule; Female; HIV Infec | 1993 |
Acute eosinophilic pneumonia induced by inhaled pentamidine isethionate.
Topics: Acute Disease; Administration, Inhalation; Adult; Female; HIV Infections; Humans; Pentamidine; Pulmo | 1993 |
Cholestatic giant cell hepatitis associated with ultrastructural evidence of intrahepatic retroviral infection in a human immunodeficiency virus-seropositive infant.
Topics: AIDS-Related Opportunistic Infections; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; | 1993 |
[Extrapulmonary and disseminated pneumocystosis in HIV infection].
Topics: Adult; AIDS-Related Opportunistic Infections; Bone Marrow Diseases; Female; HIV Infections; Humans; | 1993 |
The effect of prophylaxis on the outcome of HIV-associated Pneumocystis carinii pneumonia.
Topics: Adult; Antifungal Agents; HIV Infections; Humans; Middle Aged; Patient Compliance; Pentamidine; Pneu | 1996 |
[Prescription of antiretroviral and prophylactic drugs in HIV diseases: reality of medical practices].
Topics: Anti-Infective Agents; Antiviral Agents; CD4 Lymphocyte Count; Dapsone; Didanosine; Drug Utilization | 1995 |
Community-acquired bacteremia in HIV-positive patients: protective benefit of co-trimoxazole.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Bacteremia; Community-Acquired | 1996 |
Inhalatory pentamidine therapy and the duration of the QT interval in HIV-infected patients.
Topics: Administration, Inhalation; Adult; Antibiotic Prophylaxis; Antifungal Agents; CD4 Lymphocyte Count; | 1997 |
Prior antimicrobials and staphylococcal bacteremia in HIV-infected patients.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Bacteremia; Case-Control Studie | 1997 |
Severe hyperglycemia in an HIV clinic: preexisting versus drug-associated diabetes mellitus.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-HIV Agents; Diabetes Complications; Diabetes Mellitus; Di | 1998 |
Use of adjunctive corticosteroids in severe adult non-HIV Pneumocystis carinii pneumonia.
Topics: Anti-Infective Agents; Antifungal Agents; Drug Therapy, Combination; Female; Glucocorticoids; HIV In | 1998 |
[Spontaneous pneumothorax associated with human immunodeficiency virus (HIV) infection].
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Drainage; Female; HIV Infection | 1998 |
Pneumocystis carinii pneumonia incidence and chemoprophylaxis failure in ambulatory HIV-infected patients. HIV Outpatient Study (HOPS) Investigators.
Topics: Adult; AIDS-Related Opportunistic Infections; Ambulatory Care; Anti-Infective Agents; Antifungal Age | 1998 |
[Epidemiologic characteristics of cerebral toxoplasmosis in 399 HIV-infected patients followed between 1983 and 1994].
Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Anti-Infective Agents; Antibodies, Protozoan; | 1998 |
Butyl nitrite-induced acrocyanosis in an HIV-infected patient.
Topics: Acrodermatitis; Adult; Cyanosis; Didanosine; HIV Infections; Humans; Male; Nitrites; Nose Diseases; | 1999 |
Serum neopterin concentrations during treatment of leishmaniasis: useful as test of cure?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimony Sodium Gluconate; Antiprotozoal Agents | 2000 |
Hepatitis B and C viral infections in Indian kala-azar patients receiving injectable anti-leishmanial drugs: a community-based study.
Topics: Adolescent; Adult; Amphotericin B; Antimony Sodium Gluconate; Antiprotozoal Agents; Child; Equipment | 2000 |
Maintenance itraconazole for visceral leishmaniasis in HIV infection.
Topics: Adult; Antifungal Agents; Female; HIV Infections; Humans; Itraconazole; Ketoconazole; Leishmaniasis, | 1992 |
From the Centers for Disease Control. Recommendations for prophylaxis against Pneumocystis carinii pneumonia for adults and adolescents infected with HIV.
Topics: Administration, Oral; Adolescent; Adult; Aerosols; CD4-Positive T-Lymphocytes; Child; Clinical Proto | 1992 |
Recommendations for prophylaxis against Pneumocystis carinii pneumonia for adults and adolescents infected with human immunodeficiency virus.
Topics: Administration, Oral; Adolescent; Adult; Aerosols; CD4-Positive T-Lymphocytes; Child; Clinical Proto | 1992 |
Prevention of Pneumocystis carinii pneumonia and toxoplasmic encephalitis in human immunodeficiency virus infected patients: a clinical approach comparing aerosolized pentamidine and pyrimethamine/sulfadoxine.
Topics: Adult; Aerosols; Aged; CD4-Positive T-Lymphocytes; Drug Combinations; Encephalitis; Female; HIV Infe | 1992 |
Patient tolerance of nebulized pentamidine or cotrimoxazole as secondary prophylaxis for Pneumocystis carinii pneumonia.
Topics: Administration, Inhalation; Administration, Oral; Adult; HIV Infections; Humans; Male; Nebulizers an | 1992 |
Human immunodeficiency virus infection during pregnancy.
Topics: Abnormalities, Drug-Induced; AIDS Serodiagnosis; Ethics, Medical; Female; HIV Infections; Humans; In | 1992 |
Managing a patient with progressive HIV disease.
Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; HIV Infections; Humans; Pentamidine; T | 1992 |
Low incidence of Pneumocystis carinii pneumonia in HIV patients receiving 300 mg pentamidine aerosol every 2 weeks.
Topics: Administration, Inhalation; Adult; Aged; AIDS-Related Opportunistic Infections; Drug Administration | 1992 |
Characteristics and outcome variables of HIV cases at a university-based medical practice.
Topics: Adult; Female; Follow-Up Studies; HIV Infections; Humans; Male; Middle Aged; Opportunistic Infection | 1992 |
Visceral leishmaniasis and HIV infection: unusual presentation with pleuropulmonary involvement, and effect of secondary prophylaxis.
Topics: HIV Infections; Humans; Leishmaniasis, Visceral; Lung Diseases, Parasitic; Male; Middle Aged; Opport | 1992 |
[Pneumocystis carinii pneumonia in a HIV-positive patient].
Topics: Acquired Immunodeficiency Syndrome; Adult; Bronchoalveolar Lavage Fluid; HIV Infections; HIV Seropos | 1992 |
Aerosolized pentamidine: a well-tolerated mode of prophylaxis against Pneumocystis carinii pneumonia in older children with human immunodeficiency virus infection.
Topics: Administration, Inhalation; Adolescent; Child; Child, Preschool; Female; HIV Infections; Humans; Mal | 1992 |
Exposure of health care workers to aerosolized pentamidine.
Topics: Aerosols; Air Pollutants, Occupational; Chromatography, High Pressure Liquid; Cough; HIV Infections; | 1992 |
Visceral leishmaniasis in an HIV-infected patient: clinical features and response to treatment.
Topics: Adult; AIDS Serodiagnosis; Antimony Sodium Gluconate; CD4-CD8 Ratio; HIV Infections; HIV-1; Humans; | 1991 |
Guidelines for prophylaxis against Pneumocystis carinii pneumonia for children infected with human immunodeficiency virus.
Topics: Aerosols; CD4-Positive T-Lymphocytes; Child; Child, Preschool; Clinical Protocols; Dapsone; Drug Adm | 1991 |
From the Centers for Disease Control. Guidelines for prophylaxis against Pneumocystis carinii pneumonia for children infected with human immunodeficiency virus.
Topics: Aerosols; CD4-Positive T-Lymphocytes; Child; Child, Preschool; Clinical Protocols; Dapsone; Drug Adm | 1991 |
Clinical and laboratory correlates of Pneumocystis carinii pneumonia in children infected with HIV.
Topics: CD4-Positive T-Lymphocytes; Child, Preschool; Female; HIV Infections; Humans; Infant; Leukocyte Coun | 1991 |
Pneumothorax and aerosolised pentamidine prophylaxis.
Topics: Aerosols; HIV Infections; Humans; Pentamidine; Pneumothorax | 1991 |
Predicting risk of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected children.
Topics: Biomarkers; CD4-Positive T-Lymphocytes; Child; Child, Preschool; HIV Infections; Humans; Immunoglobu | 1991 |
Low-dose multidrug chemotherapy plus Pneumocystis carinii pneumonia prophylaxis for HIV-related Kaposi's sarcoma.
Topics: Administration, Inhalation; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Doxoru | 1990 |
High incidence of bronchospasm with regular administration of aerosolized pentamidine.
Topics: Aerosols; Albuterol; Bronchial Spasm; Forced Expiratory Volume; HIV Infections; Humans; Pentamidine; | 1992 |
Deposition of aerosolized pentamidine and failure of pneumocystis prophylaxis.
Topics: Aerosols; HIV Infections; Humans; Lung; Pentamidine; Pneumonia, Pneumocystis; Risk Factors | 1992 |
[The effect of inhaled pentamidine in the radiology of Pneumocystis carinii pneumonia].
Topics: Administration, Inhalation; HIV Infections; HIV-1; Humans; Lung; Opportunistic Infections; Pentamidi | 1991 |
Pentamidine-associated nephrotoxicity and hyperkalemia in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Monitoring; Female; HIV Infections; Humans; Hyperkal | 1991 |
[HIV pneumonia: a change in attitude? Cotrimoxazole is favored for prevention].
Topics: HIV Infections; Humans; Pentamidine; Pneumonia, Pneumocystis; Trimethoprim, Sulfamethoxazole Drug Co | 1991 |
Visceral leishmaniasis in HIV-infected patients.
Topics: Adult; Amphotericin B; Antiprotozoal Agents; Female; HIV Infections; Humans; Leishmaniasis, Visceral | 1991 |
Nebulized pentamidine as prophylaxis for Pneumocystis carinii pneumonia.
Topics: Administration, Inhalation; HIV Infections; Humans; Pentamidine; Pneumonia, Pneumocystis; Premedicat | 1991 |
[Prevention of pneumocystosis with pentamidine aerosols].
Topics: Aerosols; HIV Infections; Humans; Opportunistic Infections; Pentamidine; Pneumonia, Pneumocystis | 1991 |
[Pneumocystis carinii pneumonia: possible applications of pentamidine aerosol in hematology, oncology and transplantation medicine].
Topics: Aerosols; HIV Infections; Humans; Immunologic Deficiency Syndromes; Opportunistic Infections; Pentam | 1991 |
Pentamidine prophylaxis of Pneumocystis carinii pneumonia.
Topics: HIV Infections; Humans; Pentamidine; Pneumonia, Pneumocystis | 1991 |
Effect of aerosolized pentamidine prophylaxis on the diagnosis of Pneumocystis carinii pneumonia by induced sputum examination in patients infected with the human immunodeficiency virus.
Topics: Aerosols; Bronchoalveolar Lavage Fluid; HIV Infections; HIV-1; Humans; Lung; Pentamidine; Pneumocyst | 1991 |
Pentamidine aerosol increases the number of alveolar macrophages in HIV-infected patients.
Topics: Administration, Inhalation; Adult; Aerosols; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cell Count; | 1991 |
Urine pentamidine as an indicator of lung pentamidine in patients receiving aerosol therapy.
Topics: Administration, Inhalation; Adult; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liqui | 1991 |
Upper lobe relapse of Pneumocystis carinii pneumonia during aerosolized pentamidine prophylaxis.
Topics: Adult; Aerosols; HIV Infections; Humans; Male; Opportunistic Infections; Pentamidine; Pneumonia, Pne | 1991 |
[When and how should primary prevention against Pneumocystis carinii pneumonia be carried out in HIV infection?].
Topics: CD4-Positive T-Lymphocytes; HIV Infections; Humans; Pentamidine; Pneumonia, Pneumocystis; Trimethopr | 1990 |
Clinical aspects of HIV and AIDS.
Topics: Acquired Immunodeficiency Syndrome; Fluconazole; Ganciclovir; HIV Infections; Humans; Opportunistic | 1990 |
[Management and early treatment of patients infected with HIV. Synthesis of recommendations of an expert group convened by the french minister of Solidarité, Santé et Protection sociale].
Topics: Aerosols; CD4-Positive T-Lymphocytes; Clinical Protocols; Delivery of Health Care; France; HIV Infec | 1990 |
Pulmonary tolerance of prophylactic aerosolized pentamidine in human immunodeficiency virus-infected patients.
Topics: Aerosols; Cohort Studies; Drug Tolerance; Forced Expiratory Volume; HIV Infections; Humans; Lung; Ox | 1991 |
Factors determining pulmonary deposition of aerosolized pentamidine in patients with human immunodeficiency virus infection.
Topics: Aerosols; Bronchoalveolar Lavage Fluid; HIV Infections; Humans; Lung; Pentamidine; Pneumonia, Pneumo | 1991 |
Factors determining pulmonary deposition of aerosolized pentamidine in patients with human immunodeficiency virus infection.
Topics: Aerosols; Bronchoalveolar Lavage Fluid; HIV Infections; Humans; Lung; Pentamidine; Pneumonia, Pneumo | 1991 |
Factors determining pulmonary deposition of aerosolized pentamidine in patients with human immunodeficiency virus infection.
Topics: Aerosols; Bronchoalveolar Lavage Fluid; HIV Infections; Humans; Lung; Pentamidine; Pneumonia, Pneumo | 1991 |
Factors determining pulmonary deposition of aerosolized pentamidine in patients with human immunodeficiency virus infection.
Topics: Aerosols; Bronchoalveolar Lavage Fluid; HIV Infections; Humans; Lung; Pentamidine; Pneumonia, Pneumo | 1991 |
Factors determining pulmonary deposition of aerosolized pentamidine in patients with human immunodeficiency virus infection.
Topics: Aerosols; Bronchoalveolar Lavage Fluid; HIV Infections; Humans; Lung; Pentamidine; Pneumonia, Pneumo | 1991 |
Factors determining pulmonary deposition of aerosolized pentamidine in patients with human immunodeficiency virus infection.
Topics: Aerosols; Bronchoalveolar Lavage Fluid; HIV Infections; Humans; Lung; Pentamidine; Pneumonia, Pneumo | 1991 |
Factors determining pulmonary deposition of aerosolized pentamidine in patients with human immunodeficiency virus infection.
Topics: Aerosols; Bronchoalveolar Lavage Fluid; HIV Infections; Humans; Lung; Pentamidine; Pneumonia, Pneumo | 1991 |
Factors determining pulmonary deposition of aerosolized pentamidine in patients with human immunodeficiency virus infection.
Topics: Aerosols; Bronchoalveolar Lavage Fluid; HIV Infections; Humans; Lung; Pentamidine; Pneumonia, Pneumo | 1991 |
Factors determining pulmonary deposition of aerosolized pentamidine in patients with human immunodeficiency virus infection.
Topics: Aerosols; Bronchoalveolar Lavage Fluid; HIV Infections; Humans; Lung; Pentamidine; Pneumonia, Pneumo | 1991 |
Effect of terbutaline on bronchoconstriction induced by nebulised pentamidine.
Topics: Administration, Inhalation; Adult; Bronchoconstriction; Drug Therapy, Combination; Forced Expiratory | 1991 |
[Preventive pentamidine inhalation in patients with HIV infection (CD3 and CD4) in ambulatory practice].
Topics: Administration, Inhalation; Adult; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; CD4 Antigen | 1990 |
Infectious disease emergencies in persons with HIV/AIDS: an update.
Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Clindamycin; Communicable Diseases; Fluconazole; | 1990 |
Can pentamidine prevent pneumonia in HIV patients?
Topics: HIV Infections; HIV-1; Humans; Multicenter Studies as Topic; Pentamidine; Pneumonia, Pneumocystis | 1990 |
Aerosolized pentamidine: effect on diagnosis and presentation of Pneumocystis carinii pneumonia.
Topics: Aerosols; Biopsy; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoscopy; Gallium Radioisotopes; HIV In | 1990 |
[Pentamidine in the treatment of pneumocystosis].
Topics: HIV Infections; Humans; Opportunistic Infections; Pentamidine; Pneumonia, Pneumocystis | 1990 |
[Pharmacologic studies with pentamidine aerosol in HIV patients].
Topics: Administration, Inhalation; HIV Infections; Humans; Infusions, Intravenous; Metabolic Clearance Rate | 1990 |
More on the expanded use of aerosolized pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Aerosols; HIV Infections; HIV Seropositivity; Humans; Pentamidin | 1989 |
PHS issues guidelines for P. carinii pneumonia prophylaxis.
Topics: Adult; CD4 Antigens; Child, Preschool; Follow-Up Studies; HIV Infections; Humans; Infant; Leukocyte | 1989 |
Anti-pneumonia AIDS drug.
Topics: Aerosols; HIV Infections; Humans; Pentamidine; Pneumonia, Pneumocystis | 1989 |
Primary care for patients with human immunodeficiency virus (HIV) infection in a methadone maintenance treatment program.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Female; HIV Infections; Humans; Male; Methadone | 1989 |