Page last updated: 2024-11-02

pentamidine and Fasting Hypoglycemia

pentamidine has been researched along with Fasting Hypoglycemia in 32 studies

Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

Fasting Hypoglycemia: HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast.

Research Excerpts

ExcerptRelevanceReference
"Both co-trimoxazole and pentamidine are used for the treatment of pneumocystis pneumonia (PCP) and are known to cause hypoglycemia as an adverse drug reaction."7.91Consecutive hypoglycemia attacks induced by co-trimoxazole followed by pentamidine in a patient with acquired immunodeficiency syndrome. ( Asagiri, T; Nakamura, M; Okazaki, M; Takeuchi, S, 2019)
"To describe the association between acute choreoathetosis/ballismus and hypoglycemia related to pentamidine therapy in a patient with the acquired immunodeficiency syndrome."7.69Choreoathetosis/ballismus associated with pentamidine-induced hypoglycemia in a patient with the acquired immunodeficiency syndrome. ( Churchill, DR; Edgecombe, J; Harrison, MJ; Miller, RF; Sweeney, BJ, 1994)
"Pentamidine can cause hypoglycemia followed by hyperglycemia."7.67Diabetogenic effect of pentamidine. In vitro and in vivo studies in a patient with malignant insulinoma. ( Falko, JM; Nelson, KP; Osei, K; Stephens, R, 1984)
"In 1984, three patients died of severe hypoglycemia after receiving pentamidine isethionate to treat Pneumocystis pneumonia."7.67Risk factors for hypoglycemia associated with pentamidine therapy for Pneumocystis pneumonia. ( Helmick, CG; Sattler, FR; Stehr-Green, JK; Waskin, H, 1988)
"We conducted an analysis of 37 patients with the acquired immune deficiency syndrome (AIDS) who received pentamidine for the treatment of Pneumocystis carinii pneumonia to quantitate the incidence and severity of pentamidine-induced hypoglycemia."7.67Pentamidine-induced hypoglycemia in patients with the acquired immune deficiency syndrome. ( Kalman, CM; Laskin, OL; Stahl-Bayliss, CM, 1986)
"Four patients, treated with pentamidine because of Pneumocystis carinii pneumonitis, displayed severe fasting hypoglycemia during this treatment."7.66Diabetes mellitus following pentamidine-induced hypoglycemia in humans. ( Assan, R; Bouchard, P; Caubarrère, I; Ganeval, D; Reach, G; Sai, P, 1982)
"In this prospective study, 26 AIDS patients with 32 episodes of PCP were treated with pentamidine (4 mg/kg/d)."5.28Higher pentamidine levels in AIDS patients with hypoglycemia and azotemia during treatment of Pneumocystis carinii pneumonia. ( Comtois, R; Gervais, A; Lemieux, C; Pouliot, J; Vinet, B, 1992)
"Pentamidine has been recognised for its potential to cause symptomatic, and even life-threatening hypoglycaemia."5.28Diabetes mellitus presenting with ketoacidosis following pentamidine therapy in patients with acquired immunodeficiency syndrome. ( Herchline, TE; Para, MF; Plouffe, JF, 1991)
" The dysglycaemic patients (hypo- and hyper-glycaemic) had a higher pentamidine dosage (p less than 0."5.28Hypoglycaemia and diabetes mellitus following parenteral pentamidine mesylate treatment in AIDS patients. ( Assan, D; Assan, R; Bricaire, F; Leport, C; Perronne, C; Vilde, JL, 1990)
"Both co-trimoxazole and pentamidine are used for the treatment of pneumocystis pneumonia (PCP) and are known to cause hypoglycemia as an adverse drug reaction."3.91Consecutive hypoglycemia attacks induced by co-trimoxazole followed by pentamidine in a patient with acquired immunodeficiency syndrome. ( Asagiri, T; Nakamura, M; Okazaki, M; Takeuchi, S, 2019)
"To describe the association between acute choreoathetosis/ballismus and hypoglycemia related to pentamidine therapy in a patient with the acquired immunodeficiency syndrome."3.69Choreoathetosis/ballismus associated with pentamidine-induced hypoglycemia in a patient with the acquired immunodeficiency syndrome. ( Churchill, DR; Edgecombe, J; Harrison, MJ; Miller, RF; Sweeney, BJ, 1994)
"Pentamidine can cause hypoglycemia followed by hyperglycemia."3.67Diabetogenic effect of pentamidine. In vitro and in vivo studies in a patient with malignant insulinoma. ( Falko, JM; Nelson, KP; Osei, K; Stephens, R, 1984)
"In 1984, three patients died of severe hypoglycemia after receiving pentamidine isethionate to treat Pneumocystis pneumonia."3.67Risk factors for hypoglycemia associated with pentamidine therapy for Pneumocystis pneumonia. ( Helmick, CG; Sattler, FR; Stehr-Green, JK; Waskin, H, 1988)
"We conducted an analysis of 37 patients with the acquired immune deficiency syndrome (AIDS) who received pentamidine for the treatment of Pneumocystis carinii pneumonia to quantitate the incidence and severity of pentamidine-induced hypoglycemia."3.67Pentamidine-induced hypoglycemia in patients with the acquired immune deficiency syndrome. ( Kalman, CM; Laskin, OL; Stahl-Bayliss, CM, 1986)
"Four patients, treated with pentamidine because of Pneumocystis carinii pneumonitis, displayed severe fasting hypoglycemia during this treatment."3.66Diabetes mellitus following pentamidine-induced hypoglycemia in humans. ( Assan, R; Bouchard, P; Caubarrère, I; Ganeval, D; Reach, G; Sai, P, 1982)
"Pentamidine was frequently associated with dysglycaemia due to its pancreatic beta-cell cytotoxic effects but is now used less often to treat Pneumocystis carinii pneumonia in immunosuppressed patients."2.39Drug-induced disorders of glucose metabolism. Mechanisms and management. ( Chan, JC; Cockram, CS; Critchley, JA, 1996)
"The pentamidine-treated dysglycemic patients differed from their euglycemic counterparts by higher pentamidine doses (P < 0."1.29Pentamidine-induced derangements of glucose homeostasis. Determinant roles of renal failure and drug accumulation. A study of 128 patients. ( Assan, D; Assan, R; Chotard, L; Matheron, S; Mayaud, C; Perronne, C; Zucman, D, 1995)
"In this prospective study, 26 AIDS patients with 32 episodes of PCP were treated with pentamidine (4 mg/kg/d)."1.28Higher pentamidine levels in AIDS patients with hypoglycemia and azotemia during treatment of Pneumocystis carinii pneumonia. ( Comtois, R; Gervais, A; Lemieux, C; Pouliot, J; Vinet, B, 1992)
"Pentamidine has been recognised for its potential to cause symptomatic, and even life-threatening hypoglycaemia."1.28Diabetes mellitus presenting with ketoacidosis following pentamidine therapy in patients with acquired immunodeficiency syndrome. ( Herchline, TE; Para, MF; Plouffe, JF, 1991)
" The dysglycaemic patients (hypo- and hyper-glycaemic) had a higher pentamidine dosage (p less than 0."1.28Hypoglycaemia and diabetes mellitus following parenteral pentamidine mesylate treatment in AIDS patients. ( Assan, D; Assan, R; Bricaire, F; Leport, C; Perronne, C; Vilde, JL, 1990)
"Oral diazoxide was effective in reversing the marked hypoglycaemia."1.27Reversal of pentamidine-induced hypoglycaemia with oral diazoxide. ( Fitzgerald, DB; Young, IS, 1984)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199020 (62.50)18.7374
1990's9 (28.13)18.2507
2000's1 (3.13)29.6817
2010's2 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Okazaki, M2
Nakamura, M1
Asagiri, T1
Takeuchi, S1
Deschamps, JY1
Desquesnes, M1
Dorso, L1
Ravel, S1
Bossard, G1
Charbonneau, M1
Garand, A1
Roux, FA1
KLINKHAMER, LV1
Osei, K1
Falko, JM1
Nelson, KP1
Stephens, R1
Ganda, OP1
Fitzgerald, DB1
Young, IS1
Sharpe, SM1
Roig Cutillas, J1
de Gracia Roldán, J1
Ruiz Manzano, J1
Martínez Martínez, M1
Bernardo Turmo, L1
Morera Prat, J1
Bouchard, P2
Sai, P1
Reach, G1
Caubarrère, I1
Ganeval, D2
Assan, R4
Siddiqui, MA1
Ford, PA1
Perronne, C2
Assan, D2
Chotard, L1
Mayaud, C1
Matheron, S1
Zucman, D1
Sweeney, BJ1
Edgecombe, J1
Churchill, DR1
Miller, RF1
Harrison, MJ1
Moreno, I1
Gonzalo, MA1
Fernández Guerrero, M1
Herrera-Pombo, JL1
Chan, JC1
Cockram, CS1
Critchley, JA1
Grant, AM1
Sandler, RM1
Carrell, RW1
Caubarrière, I1
Even, P1
Comtois, R2
Pouliot, J2
Gervais, A2
Vinet, B2
Lemieux, C2
Herchline, TE1
Plouffe, JF1
Para, MF1
Bricaire, F1
Leport, C1
Vilde, JL1
Lingenfelser, T1
Glück, T1
Scheurlen, M1
Overkamp, D1
Jakober, B1
Pierone, G1
Masci, JR1
Nicholas, P1
Katzin, L1
Waskin, H2
Stehr-Green, JK1
Helmick, CG1
Sattler, FR2
Karboski, JA1
Godley, PJ1
Estopiñán, V1
Montilla, P1
Riobó, P1
de la Calle, H1
Stahl-Bayliss, CM1
Kalman, CM1
Laskin, OL1
Spadafora, MP1
Roberts, JR1
Andersen, R1
Boedicker, M1
Ma, M1
Goldstein, EJ1

Reviews

1 review available for pentamidine and Fasting Hypoglycemia

ArticleYear
Drug-induced disorders of glucose metabolism. Mechanisms and management.
    Drug safety, 1996, Volume: 15, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin-Converti

1996

Other Studies

31 other studies available for pentamidine and Fasting Hypoglycemia

ArticleYear
Consecutive hypoglycemia attacks induced by co-trimoxazole followed by pentamidine in a patient with acquired immunodeficiency syndrome.
    International journal of STD & AIDS, 2019, Volume: 30, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Aged; Anti-Infective Agents; Atovaquone; Drug-Related Side Effec

2019
Refractory hypoglycaemia in a dog infected with Trypanosoma congolense.
    Parasite (Paris, France), 2016, Volume: 23

    Topics: Africa South of the Sahara; Animals; Antiprotozoal Agents; Dog Diseases; Dogs; Female; Fever; Glucos

2016
Drug-induced hypoglycaemia.
    Prescrire international, 2009, Volume: 18, Issue:100

    Topics: Anti-Bacterial Agents; Blood Glucose; Carbamates; Dextropropoxyphene; Diabetes Mellitus; Disopyramid

2009
Hypoglycaemia during pentamidine treatment for trypanosomiasis.
    Tropical and geographical medicine, 1958, Volume: 10, Issue:4

    Topics: Humans; Hypoglycemia; Pancreatic Diseases; Pentamidine; Trypanosomiasis

1958
Diabetogenic effect of pentamidine. In vitro and in vivo studies in a patient with malignant insulinoma.
    The American journal of medicine, 1984, Volume: 77, Issue:1

    Topics: Adenoma, Islet Cell; Adult; Amidines; Blood Glucose; Female; Humans; Hypoglycemia; In Vitro Techniqu

1984
Pentamidine and hypoglycemia.
    Annals of internal medicine, 1984, Volume: 100, Issue:3

    Topics: Amidines; Humans; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Pentamidine

1984
Reversal of pentamidine-induced hypoglycaemia with oral diazoxide.
    The Journal of tropical medicine and hygiene, 1984, Volume: 87, Issue:1

    Topics: Adult; Amidines; Blood Glucose; Diazoxide; Humans; Hypoglycemia; Insulin; Male; Middle Aged; Pentami

1984
Pentamidine and hypoglycemia.
    Annals of internal medicine, 1983, Volume: 99, Issue:1

    Topics: Adult; Amidines; Female; Humans; Hypoglycemia; Pentamidine; Pneumonia, Pneumocystis

1983
[Pneumocystis carinii pneumonia in a previously healthy patient].
    Medicina clinica, 1984, May-12, Volume: 82, Issue:18

    Topics: Aged; Drug Combinations; Humans; Hypoglycemia; Immunologic Deficiency Syndromes; Male; Pentamidine;

1984
Pentamidine and hypoglycemia.
    Annals of internal medicine, 1983, Volume: 99, Issue:6

    Topics: Adult; Amidines; Child; Humans; Hypoglycemia; Pentamidine

1983
Diabetes mellitus following pentamidine-induced hypoglycemia in humans.
    Diabetes, 1982, Volume: 31, Issue:1

    Topics: Adult; Aged; Amidines; Blood Glucose; Diabetes Mellitus; Humans; Hypoglycemia; Insulin; Male; Middle

1982
Acute severe autonomic insufficiency during pentamidine therapy.
    Southern medical journal, 1995, Volume: 88, Issue:10

    Topics: Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Autonomic Nerv

1995
Pentamidine-induced derangements of glucose homeostasis. Determinant roles of renal failure and drug accumulation. A study of 128 patients.
    Diabetes care, 1995, Volume: 18, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Diabetes Mellitus; Female; Humans; Hyperglycemia; Hypo

1995
Choreoathetosis/ballismus associated with pentamidine-induced hypoglycemia in a patient with the acquired immunodeficiency syndrome.
    Archives of neurology, 1994, Volume: 51, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adult; Athetosis; Chorea; Female; Humans; Hypoglycemia; Movement

1994
[Hypoglycemia secondary to intravenous pentamidine treatment without subsequent diabetes mellitus].
    Revista clinica espanola, 1993, Volume: 193, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Humans; Hypoglycemia; Injections, Intravenous; Male; P

1993
Hypoglycaemic effect of pentamidine detected by glucose screen.
    Lancet (London, England), 1977, Sep-03, Volume: 2, Issue:8036

    Topics: Aged; Amidines; Blood Glucose; Humans; Hypoglycemia; Male; Pentamidine; Pneumonia, Pneumocystis

1977
[Pentamidine, hypoglycemia, diabetes mellitus].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1978

    Topics: Adult; Amidines; Diabetes Mellitus; Female; Humans; Hypoglycemia; Male; Middle Aged; Pentamidine; Pn

1978
High pentamidine levels associated with hypoglycemia and azotemia in a patient with Pneumocystis carinii pneumonia.
    Diagnostic microbiology and infectious disease, 1992, Volume: 15, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Humans; Hypoglycemia; Male; Middle Aged; Pentamidine; Pneumon

1992
Higher pentamidine levels in AIDS patients with hypoglycemia and azotemia during treatment of Pneumocystis carinii pneumonia.
    The American review of respiratory disease, 1992, Volume: 146, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Analysis of Variance; Chi-Square Distribution; Female; Hu

1992
Diabetes mellitus presenting with ketoacidosis following pentamidine therapy in patients with acquired immunodeficiency syndrome.
    The Journal of infection, 1991, Volume: 22, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Diabetes Complications; Diabetic Ketoacidosis; Humans; Hy

1991
Hypoglycaemia and diabetes mellitus following parenteral pentamidine mesylate treatment in AIDS patients.
    Diabetic medicine : a journal of the British Diabetic Association, 1990, Volume: 7, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Diabetes Mellitus; Female; Humans; Hypoglycemia; Ma

1990
Pentamidine and hypoglycaemia.
    Lancet (London, England), 1989, Aug-19, Volume: 2, Issue:8660

    Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Hemophilia A; Humans; Hypoglycemia; Male; Penta

1989
Pentamidine and hypoglycaemia.
    Lancet (London, England), 1989, Oct-07, Volume: 2, Issue:8667

    Topics: Humans; Hypoglycemia; Nebulizers and Vaporizers; Pentamidine; Pneumonia, Pneumocystis

1989
Hypoglycemia and pentamidine.
    The American journal of nursing, 1989, Volume: 89, Issue:1

    Topics: Amidines; Humans; Hypoglycemia; Pentamidine; Pneumonia, Pneumocystis; Retrospective Studies

1989
Risk factors for hypoglycemia associated with pentamidine therapy for Pneumocystis pneumonia.
    JAMA, 1988, Jul-15, Volume: 260, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Female; Humans; Hypoglycemia; Infant; Male; Med

1988
Inhaled pentamidine and hypoglycemia.
    Annals of internal medicine, 1988, Volume: 108, Issue:3

    Topics: Administration, Inhalation; Amidines; Humans; Hypoglycemia; Male; Middle Aged; Pentamidine

1988
[Hypoglycemia and diabetes mellitus as complications of treatment with pentamidine. Apropos of a case].
    Medicina clinica, 1988, Apr-23, Volume: 90, Issue:16

    Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Diabetes Mellitus; Humans; Hypoglycemia; Male;

1988
Pentamidine-induced hypoglycemia in patients with the acquired immune deficiency syndrome.
    Clinical pharmacology and therapeutics, 1986, Volume: 39, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Blood Glucose; Female; Humans; Hypoglycemia; In

1986
Hypoglycemic coma from pentamadine in an AIDS patient.
    The American journal of emergency medicine, 1986, Volume: 4, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Coma; Humans; Hypoglycemia; Male; Pentamidine;

1986
Adverse reactions associated with pentamidine isethionate in AIDS patients: recommendations for monitoring therapy.
    Drug intelligence & clinical pharmacy, 1986, Volume: 20, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Anemia; Humans; Hypoglycemia; Male; Middle Aged

1986
Pentamidine and fatal hypoglycemia.
    Annals of internal medicine, 1987, Volume: 107, Issue:5

    Topics: Amidines; Humans; Hypoglycemia; Male; Middle Aged; Pentamidine

1987