pentamidine has been researched along with Disease Exacerbation in 7 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| ") 3 times per week, was evaluated in a double-blind, randomized, placebo-controlled trial of zidovudine (AZT)-treated asymptomatic human immunodeficiency virus (HIV)-infected subjects with 200-500 CD4 cells/mm3 at entry." | 9.08 | Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial. ( Beall, G; Blick, G; Calabrese, LH; Conant, MA; Fisher, A; Galpin, JE; Goldstein, G; Grossman, HA; Hirsch, RL; Stampone, P, 1995) |
| ") 3 times per week, was evaluated in a double-blind, randomized, placebo-controlled trial of zidovudine (AZT)-treated asymptomatic human immunodeficiency virus (HIV)-infected subjects with 200-500 CD4 cells/mm3 at entry." | 5.08 | Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial. ( Beall, G; Blick, G; Calabrese, LH; Conant, MA; Fisher, A; Galpin, JE; Goldstein, G; Grossman, HA; Hirsch, RL; Stampone, P, 1995) |
| "Primary prophylaxis against Pneumocystis carinii pneumonia (PCP) for patients with HIV infection has been recommended by the Centers for Disease Control and Prevention." | 2.67 | Aerosolized pentamidine as primary prophylaxis for Pneumocystis carinii pneumonia: efficacy, mortality and morbidity. ( Berglund, O; Elvin, K; Lidman, C; Lindbäck, S; Tynell, E, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Richter, J | 1 |
| Göbels, S | 1 |
| Göbel, T | 1 |
| Westenfeld, R | 1 |
| Müller-Stöver, I | 1 |
| Häussinger, D | 1 |
| Blanckaert, D | 1 |
| Kessioui, BE | 1 |
| Tahon, A | 1 |
| Gosselin, B | 1 |
| Lebecq, MF | 1 |
| Farriaux, JP | 1 |
| Fontaine, G | 1 |
| Milstone, AM | 1 |
| Balakrishnan, SL | 1 |
| Foster, CB | 1 |
| Chen, A | 1 |
| Balasegaram, M | 1 |
| Harris, S | 1 |
| Checchi, F | 1 |
| Hamel, C | 1 |
| Karunakara, U | 1 |
| Sabin, C | 1 |
| Pasi, J | 1 |
| Phillips, A | 1 |
| Elford, J | 1 |
| Janossy, G | 1 |
| Lee, C | 1 |
| Goldstein, G | 1 |
| Conant, MA | 1 |
| Beall, G | 1 |
| Grossman, HA | 1 |
| Galpin, JE | 1 |
| Blick, G | 1 |
| Calabrese, LH | 1 |
| Hirsch, RL | 1 |
| Fisher, A | 1 |
| Stampone, P | 1 |
| Lidman, C | 1 |
| Berglund, O | 1 |
| Tynell, E | 1 |
| Lindbäck, S | 1 |
| Elvin, K | 1 |
2 trials available for pentamidine and Disease Exacerbation
| Article | Year |
|---|---|
Safety and efficacy of thymopentin in zidovudine (AZT)-treated asymptomatic HIV-infected subjects with 200-500 CD4 cells/mm3: a double-blind placebo-controlled trial.
Topics: Adult; CD4 Lymphocyte Count; Disease Progression; Double-Blind Method; Drug Resistance, Microbial; D | 1995 |
Aerosolized pentamidine as primary prophylaxis for Pneumocystis carinii pneumonia: efficacy, mortality and morbidity.
Topics: Absenteeism; Acquired Immunodeficiency Syndrome; Adult; Aerosols; AIDS-Related Opportunistic Infecti | 1994 |
5 other studies available for pentamidine and Disease Exacerbation
| Article | Year |
|---|---|
A returning traveller with fever, facial swelling, and skin lesions.
Topics: Adrenal Cortex Hormones; Animals; Diagnosis, Differential; Disease Progression; Face; Fever; Humans; | 2012 |
[Pneumocystis carinii pneumonia without immunodeficiency in a child].
Topics: Animal Husbandry; Animals; Antiprotozoal Agents; Biopsy; Birds; Child, Preschool; Disease Progressio | 1978 |
Failure of intravenous pentamidine prophylaxis to prevent pneumocystis pneumonia in a pediatric hematopoietic stem cell transplant (HSCT) patient.
Topics: Acute Disease; Antibiotic Prophylaxis; Disease Progression; Fatal Outcome; Hematopoietic Stem Cell T | 2006 |
Treatment outcomes and risk factors for relapse in patients with early-stage human African trypanosomiasis (HAT) in the Republic of the Congo.
Topics: Adolescent; Adult; Animals; Child; Cohort Studies; Democratic Republic of the Congo; Disease Progres | 2006 |
CD4+ counts before and after switching to monoclonal high-purity factor VIII concentrate in HIV-infected haemophilic patients.
Topics: Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Child; Child, | 1994 |