pentamidine has been researched along with Diabetes Mellitus, Type 1 in 10 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twelve cases of diabetes mellitus following pentamidine isethionate ( Lomidine ) treatment for antimonial -resistant cases of kala-azar are reported." | 7.67 | Pentamidine-induced diabetes mellitus. ( Jha, TK; Sharma, VK, 1984) |
| "Twelve cases of diabetes mellitus following pentamidine isethionate ( Lomidine ) treatment for antimonial -resistant cases of kala-azar are reported." | 3.67 | Pentamidine-induced diabetes mellitus. ( Jha, TK; Sharma, VK, 1984) |
| " Two patients with advanced stages of the disease were treated with polychemotherapy (pentamidine and allopurinol) combined with recombinant human interferon-gamma (rIFN-gamma)." | 1.30 | The efficacy of pentamidine combined with allopurinol and immunotherapy for the treatment of patients with diffuse cutaneous leishmaniasis. ( Becker, I; Berzunza-Cruz, M; Dominguez, JS; Morales-Vargas, A; Perez-Montfort, R; Ruiz-Remigio, A; Salaiza-Suazo, N; Velasco-Castrejon, O; Volkow, P, 1999) |
| "Pentamidine is known to cause severe dysglycaemia by damaging beta-cell function of the pancreas." | 1.29 | Insulin-dependent diabetes mellitus following pentamidine therapy in a patient with AIDS. ( Bogner, JR; Goebel, FD; Liegl, U, 1994) |
| "Pentamidine which is an agent usually used to treat leishmaniasis and trypanosomiasis, but it is an alternative for P." | 1.28 | [Diabetes mellitus induced by pentamidine, without previous episodes of hypoglycemia, in patients with AIDS]. ( Caso, E; del Arco, C; García-Polo, I; Gómez-Pan, A; Noguerado, A; Santos, I, 1990) |
| " Dosage adjustment or alternative therapy should be considered with the onset of toxicity." | 1.28 | Insulin-dependent diabetes mellitus associated with pentamidine. ( Collins, J; Houk, JH; Pien, FD, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jha, TK | 1 |
| Sharma, VK | 1 |
| Blanc, MH | 1 |
| Liegl, U | 1 |
| Bogner, JR | 1 |
| Goebel, FD | 1 |
| Becker, I | 1 |
| Volkow, P | 1 |
| Velasco-Castrejon, O | 1 |
| Salaiza-Suazo, N | 1 |
| Berzunza-Cruz, M | 1 |
| Dominguez, JS | 1 |
| Morales-Vargas, A | 1 |
| Ruiz-Remigio, A | 1 |
| Perez-Montfort, R | 1 |
| Herrmann, BL | 1 |
| Saller, B | 1 |
| Sauer, J | 1 |
| Brockmeyer, N | 1 |
| Mann, K | 1 |
| Morin, D | 1 |
| Dumas, ML | 1 |
| Valette, H | 1 |
| Dumas, R | 1 |
| Millard, PS | 1 |
| van der Horst, C | 1 |
| Santos, I | 1 |
| del Arco, C | 1 |
| García-Polo, I | 1 |
| Noguerado, A | 1 |
| Caso, E | 1 |
| Gómez-Pan, A | 1 |
| Shen, M | 1 |
| Orwoll, ES | 1 |
| Conte, JE | 1 |
| Prince, MJ | 1 |
| Collins, J | 1 |
| Pien, FD | 1 |
| Houk, JH | 1 |
1 review available for pentamidine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
[AIDS and diabetes].
Topics: Acquired Immunodeficiency Syndrome; Anti-Infective Agents; Antimetabolites; Antineoplastic Agents, H | 1995 |
9 other studies available for pentamidine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Pentamidine-induced diabetes mellitus.
Topics: Amidines; Diabetes Mellitus; Diabetes Mellitus, Type 1; Humans; Leishmaniasis, Visceral; Pentamidine | 1984 |
Insulin-dependent diabetes mellitus following pentamidine therapy in a patient with AIDS.
Topics: AIDS-Related Opportunistic Infections; Diabetes Mellitus, Type 1; Humans; Male; Middle Aged; Pentami | 1994 |
The efficacy of pentamidine combined with allopurinol and immunotherapy for the treatment of patients with diffuse cutaneous leishmaniasis.
Topics: Adult; Allopurinol; Animals; Antiprotozoal Agents; Combined Modality Therapy; Diabetes Mellitus, Typ | 1999 |
[26-year-old patient with cutaneous leishmaniasis and an initial diabetes mellitus manifestation].
Topics: Adult; Antiprotozoal Agents; Diabetes Mellitus, Type 1; Drug Administration Schedule; Female; Follow | 1999 |
[Transitory acute kidney insufficiency and insulin-dependent after treatment of kala-azar with pentamidine and N-methylglucamine antimony].
Topics: Acute Kidney Injury; Antimony; Antiprotozoal Agents; Child, Preschool; Diabetes Mellitus, Type 1; Hu | 1991 |
Reversible diabetes mellitus after intravenous pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Diabetes Mellitus, Type 1; Humans; Male; Middle A | 1991 |
[Diabetes mellitus induced by pentamidine, without previous episodes of hypoglycemia, in patients with AIDS].
Topics: Acquired Immunodeficiency Syndrome; Adult; Diabetes Mellitus, Type 1; Humans; Male; Pentamidine; Pne | 1990 |
Pentamidine-induced pancreatic beta-cell dysfunction.
Topics: Acquired Immunodeficiency Syndrome; Amidines; Chromatography, High Pressure Liquid; Diabetes Mellitu | 1989 |
Insulin-dependent diabetes mellitus associated with pentamidine.
Topics: Adult; Amidines; Diabetes Mellitus, Type 1; Humans; Male; Pentamidine; Pneumonia, Pneumocystis | 1989 |