pentamidine has been researched along with Cystic Fibrosis in 3 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Well-controlled studies of aerosolized antibiotics in cystic fibrosis demonstrate that tobramycin on a cyclical basis may reduce sputum volume, bacterial counts, and improve pulmonary function." | 4.80 | Inhaled antimicrobial therapy. ( Faris, M; O'Riordan, T, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smaldone, GC | 1 |
| O'Riordan, T | 1 |
| Faris, M | 1 |
| Kuriyama, S | 1 |
| Panosian, C | 1 |
2 reviews available for pentamidine and Cystic Fibrosis
| Article | Year |
|---|---|
Inhaled antimicrobial therapy.
Topics: Administration, Inhalation; Aerosols; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; | 1999 |
Respiratory pharmacology. Antibiotics. II. Aminoglycosides, polymyxins, vancomycin, trimethoprim-sulfamethoxazole, and pentamidine.
Topics: Aminoglycosides; Anti-Bacterial Agents; Cystic Fibrosis; Drug Combinations; Drug Resistance, Microbi | 1986 |
1 other study available for pentamidine and Cystic Fibrosis
| Article | Year |
|---|---|
Deposition patterns of nebulized drugs: is the pattern important?
Topics: Aerosols; Asthma; Cyclosporins; Cystic Fibrosis; Dose-Response Relationship, Drug; Gentamicins; Huma | 1994 |