pentamidine and Cyst
pentamidine has been researched along with Cyst in 5 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Acanthamoeba castellanii genotype T4 was obtained from a patient with keratitis and subjected to in vitro susceptibility testing with various antimicrobial agents, including Chlorhexidine (CHX), Pentamidine isethionate (PI)Polyhexamethylene biguanide (PHMB), and Miltefosine to assess their efficacy against Acanthamoeba trophozoites and cyst." | 8.31 | Comparing cytotoxicity and efficacy of miltefosine and standard antimicrobial agents against Acanthamoeba trophozoites and cyst forms: An in vitro study. ( Kazemirad, E; Latifi, A; Mohebali, M; Rezaian, M; Soleimani, M; Yasami, S, 2023) |
| "Treatment with either pentamidine isethionate or trimethoprim-sulfamethoxazole significantly reduces the mortality of Pneumocystis carinii pneumonia." | 7.66 | Combination of pentamidine and trimethoprim-sulfamethoxazole in therapy of Pneumocystis carinii pneumonia in rats. ( Kluge, RM; Spain, AJ; Spaulding, DM, 1978) |
| " Acanthamoeba castellanii genotype T4 was obtained from a patient with keratitis and subjected to in vitro susceptibility testing with various antimicrobial agents, including Chlorhexidine (CHX), Pentamidine isethionate (PI)Polyhexamethylene biguanide (PHMB), and Miltefosine to assess their efficacy against Acanthamoeba trophozoites and cyst." | 4.31 | Comparing cytotoxicity and efficacy of miltefosine and standard antimicrobial agents against Acanthamoeba trophozoites and cyst forms: An in vitro study. ( Kazemirad, E; Latifi, A; Mohebali, M; Rezaian, M; Soleimani, M; Yasami, S, 2023) |
| " The results show that the bis-2,2,2-trichloroethyl carbamates function effectively in a rat model for Pneumocystis pneumonia." | 3.74 | Carbamate prodrugs of N-alkylfuramidines. ( Boykin, DW; Hall, JE; Jones, SK; Rahmathullah, SM; Tidwell, RR, 2008) |
| "Treatment with either pentamidine isethionate or trimethoprim-sulfamethoxazole significantly reduces the mortality of Pneumocystis carinii pneumonia." | 3.66 | Combination of pentamidine and trimethoprim-sulfamethoxazole in therapy of Pneumocystis carinii pneumonia in rats. ( Kluge, RM; Spain, AJ; Spaulding, DM, 1978) |
| "Pneumocystis carinii was propagated in vitro with primary embryonic chick epithelial lung (CEL) cells." | 1.26 | Propagation of Pneumocystis carinii in vitro. ( Hughes, WT; Murphy, MJ; Pifer, LL, 1977) |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Rahmathullah, SM | 1 |
| Tidwell, RR | 1 |
| Jones, SK | 1 |
| Hall, JE | 1 |
| Boykin, DW | 1 |
| Latifi, A | 1 |
| Mohebali, M | 1 |
| Yasami, S | 1 |
| Soleimani, M | 1 |
| Rezaian, M | 1 |
| Kazemirad, E | 1 |
| Trigg, ME | 1 |
| Kohn, DB | 1 |
| Sondel, PM | 1 |
| Chesney, PJ | 1 |
| Pifer, LL | 1 |
| Hughes, WT | 1 |
| Murphy, MJ | 1 |
| Kluge, RM | 1 |
| Spaulding, DM | 1 |
| Spain, AJ | 1 |
Other Studies
5 other studies available for pentamidine and Cyst
| Article | Year |
|---|---|
Carbamate prodrugs of N-alkylfuramidines.
Topics: Animals; Benzamidines; Carbamates; Cysts; Disease Models, Animal; Furans; Lung; Pneumocystis carinii | 2008 |
Comparing cytotoxicity and efficacy of miltefosine and standard antimicrobial agents against Acanthamoeba trophozoites and cyst forms: An in vitro study.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Animals; Anti-Infective Agents; Chlorhexidine; Chlorocebus aet | 2023 |
Tracheal aspirate examination for Pneumocystis carinii cysts as a guide to therapy in pneumocystis pneumonia.
Topics: Adolescent; Amidines; Cysts; Drug Combinations; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; | 1983 |
Propagation of Pneumocystis carinii in vitro.
Topics: Animals; Cells, Cultured; Cysts; DNA; Immune Sera; Methods; Microscopy, Electron, Scanning; Pentamid | 1977 |
Combination of pentamidine and trimethoprim-sulfamethoxazole in therapy of Pneumocystis carinii pneumonia in rats.
Topics: Amidines; Animals; Cysts; Drug Therapy, Combination; Male; Pentamidine; Pneumonia, Pneumocystis; Rat | 1978 |