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pentamidine and Cough

pentamidine has been researched along with Cough in 8 studies

Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"Four patients who coughed during AP administration were pretreated with 10 mg metaproterenol aerosol prior to a second inhalation of AP."9.07Bronchodilator pretreatment improves aerosol deposition uniformity in HIV-positive patients who cough while inhaling aerosolized pentamidine. ( Harrison, KS; Laube, BL, 1994)
"15 patients with first episodes of Pneumocystis carinii pneumonia and the acquired immunodeficiency syndrome were treated with only aerosolised pentamidine, which they inhaled for 20 minutes every day for 21 days."7.67Aerosolised pentamidine as sole therapy for Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome. ( Brunette, EN; Corkery, KJ; Debs, RJ; Hopewell, PC; Lin, ET; Luce, JM; Montgomery, AB; Turner, J, 1987)
"Four patients who coughed during AP administration were pretreated with 10 mg metaproterenol aerosol prior to a second inhalation of AP."5.07Bronchodilator pretreatment improves aerosol deposition uniformity in HIV-positive patients who cough while inhaling aerosolized pentamidine. ( Harrison, KS; Laube, BL, 1994)
"To assess the safety and efficacy of aerosol pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS)."5.07Aerosol pentamidine for secondary prophylaxis of AIDS-related Pneumocystis carinii pneumonia. A randomized, placebo-controlled study. ( Chan, CK; Falutz, JM; Fong, IW; Gervais, A; Hyland, RH; Lawson, LM; MacFadden, D; Montaner, JS; Rachlis, AR; Renzi, PM, 1991)
" Cough-reduction measures should be taken when giving pentamidine aerosol, and patients who do cough should cover their mouths."4.78Control of tuberculosis during aerosol therapy administration. ( Chaisson, RE; McAvinue, S, 1991)
"15 patients with first episodes of Pneumocystis carinii pneumonia and the acquired immunodeficiency syndrome were treated with only aerosolised pentamidine, which they inhaled for 20 minutes every day for 21 days."3.67Aerosolised pentamidine as sole therapy for Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome. ( Brunette, EN; Corkery, KJ; Debs, RJ; Hopewell, PC; Lin, ET; Luce, JM; Montgomery, AB; Turner, J, 1987)
"Nine patients with AIDS were studied using three nebulizer systems producing different droplet size profiles: the Acorn System 22, Respirgard II, and Respirgard II with the inspiratory baffle removed."2.67Alveolar targeting of aerosol pentamidine. Toward a rational delivery system. ( Clarke, SW; Johnson, MA; Lee, CA; Newman, SP; Simonds, AK; Talaee, N, 1990)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's7 (87.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harrison, KS1
Laube, BL1
Chaisson, RE1
McAvinue, S1
O'Riordan, TG1
Smaldone, GC1
Doré, MF1
Bréchot, JM1
Orvoën-Frija, E1
Poubeau, P1
Rochemaure, J1
Montaner, JS1
Lawson, LM1
Gervais, A1
Hyland, RH1
Chan, CK1
Falutz, JM1
Renzi, PM1
MacFadden, D1
Rachlis, AR1
Fong, IW1
Simonds, AK1
Newman, SP1
Johnson, MA1
Talaee, N1
Lee, CA1
Clarke, SW1
Montgomery, AB1
Debs, RJ1
Luce, JM1
Corkery, KJ1
Turner, J1
Brunette, EN1
Lin, ET1
Hopewell, PC1

Reviews

1 review available for pentamidine and Cough

ArticleYear
Control of tuberculosis during aerosol therapy administration.
    Respiratory care, 1991, Volume: 36, Issue:9

    Topics: Aerosols; Cough; Cross Infection; HIV Infections; Humans; Nebulizers and Vaporizers; Pentamidine; Pe

1991

Trials

4 trials available for pentamidine and Cough

ArticleYear
Bronchodilator pretreatment improves aerosol deposition uniformity in HIV-positive patients who cough while inhaling aerosolized pentamidine.
    Chest, 1994, Volume: 106, Issue:2

    Topics: Adult; Aerosols; Cough; Female; Gamma Cameras; HIV Seropositivity; Humans; Lung; Male; Metaprotereno

1994
Aerosol pentamidine for secondary prophylaxis of AIDS-related Pneumocystis carinii pneumonia. A randomized, placebo-controlled study.
    Annals of internal medicine, 1991, Jun-01, Volume: 114, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Bronchial Spasm; Cough; Female; Follow-Up Studi

1991
Acute pulmonary effects of aerosolized pentamidine. A randomized controlled study. Toronto Aerosolized Pentamidine Study (TAPS) Group.
    Chest, 1990, Volume: 98, Issue:4

    Topics: Adult; Aerosols; Bronchial Spasm; Cough; Double-Blind Method; Female; Humans; Lung; Male; Pentamidin

1990
Alveolar targeting of aerosol pentamidine. Toward a rational delivery system.
    The American review of respiratory disease, 1990, Volume: 141, Issue:4 Pt 1

    Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Aerosols; Cough; Humans; Male

1990

Other Studies

3 other studies available for pentamidine and Cough

ArticleYear
Exposure of health care workers to aerosolized pentamidine.
    Chest, 1992, Volume: 101, Issue:6

    Topics: Aerosols; Air Pollutants, Occupational; Chromatography, High Pressure Liquid; Cough; HIV Infections;

1992
Acute pulmonary effects of aerosolized pentamidine.
    Chest, 1991, Volume: 100, Issue:4

    Topics: Aerosols; Bronchial Spasm; Cough; Humans; Pentamidine; Pneumonia, Pneumocystis

1991
Aerosolised pentamidine as sole therapy for Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome.
    Lancet (London, England), 1987, Aug-29, Volume: 2, Issue:8557

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Aerosols; Amidines; Cough; Drug Evaluation; Follow-U

1987