pentamidine has been researched along with Chronic Kidney Failure in 9 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The literature lacks adequate dosing guidelines for modifying pentamidine therapy in renal failure." | 2.37 | Pentamidine therapy in renal failure: case report and literature review. ( Fitzsimmons, WE; Luskin, SS, 1988) |
| " The peak plasma concentration, plasma clearance, and elimination half-life ranged from 249 +/- 80 to 227 +/- 110 ng/ml, 268 +/- 70 to 329 +/- 58 l/h, and 29 +/- 25 to 118 +/- 119 h, respectively, in groups 1 and 2." | 1.28 | Pharmacokinetics of intravenous pentamidine in patients with normal renal function or receiving hemodialysis. ( Conte, JE, 1991) |
| "carinii pneumonia secondary to AIDS and to other known causes of immune deficiency were enrolled." | 1.27 | Assessment of therapy for pneumocystis carinii pneumonia. PCP Therapy Project Group. ( Haverkos, HW, 1984) |
| "In patients with normal renal function, pentamidine elimination half-life and plasma clearance (mean +/- SD) were 6." | 1.27 | Pentamidine pharmacokinetics in patients with AIDS with impaired renal function. ( Conte, JE; Lin, ET; Upton, RA, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Petruccelli, KC | 1 |
| Couceiro, KN | 1 |
| Guerra, MDGVB | 1 |
| Vasconcelos, ZS | 1 |
| Brandão, ARJ | 1 |
| Silva, MHSE | 1 |
| Guerra, JAO | 1 |
| Lee Loy, J | 1 |
| Koratala, A | 1 |
| De Los Santos, Y | 1 |
| Chamarthi, G | 1 |
| Santos, AH | 1 |
| Alquadan, KF | 1 |
| Rybniker, J | 1 |
| Goede, V | 1 |
| Mertens, J | 1 |
| Ortmann, M | 1 |
| Kulas, W | 1 |
| Kochanek, M | 1 |
| Benzing, T | 1 |
| Arribas, JR | 1 |
| Fätkenheuer, G | 1 |
| Haverkos, HW | 1 |
| Kuller, J | 1 |
| First, MR | 1 |
| D'Achiardi, R | 1 |
| Munda, R | 1 |
| Conte, JE | 2 |
| Green, PT | 1 |
| Reents, S | 1 |
| Harman, E | 1 |
| Curtis, AB | 1 |
| Fitzsimmons, WE | 1 |
| Luskin, SS | 1 |
| Upton, RA | 1 |
| Lin, ET | 1 |
2 reviews available for pentamidine and Chronic Kidney Failure
| Article | Year |
|---|---|
Treatment of visceral leishmaniasis with intravenous pentamidine and oral fluconazole in an HIV-positive patient with chronic renal failure--a case report and brief review of the literature.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Drug Therapy, Com | 2010 |
Pentamidine therapy in renal failure: case report and literature review.
Topics: Amidines; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pentamidine; Peritoneal Dialysis; Pneu | 1988 |
7 other studies available for pentamidine and Chronic Kidney Failure
| Article | Year |
|---|---|
Treatment of tegumentary leishmaniasis in two hemodialysis patients with end-stage renal disease using two series of pentamidine.
Topics: Antiprotozoal Agents; Humans; Kidney Failure, Chronic; Leishmaniasis, Cutaneous; Pentamidine; Renal | 2021 |
Disseminated toxoplasmosis: a life-threatening complication of inadequate posttransplant prophylaxis.
Topics: Adult; Antibiotic Prophylaxis; Fatal Outcome; Heart; Humans; Kidney Failure, Chronic; Kidney Transpl | 2019 |
Assessment of therapy for pneumocystis carinii pneumonia. PCP Therapy Project Group.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Amidines; Drug Combinations; Female; Hu | 1984 |
Pneumocystis carinii pneumonia in renal transplant recipients.
Topics: Adolescent; Adult; Drug Combinations; Female; Glomerulonephritis; Graft Rejection; Humans; Kidney Fa | 1982 |
Pharmacokinetics of intravenous pentamidine in patients with normal renal function or receiving hemodialysis.
Topics: Adult; Creatinine; Female; Half-Life; Humans; Infusions, Intravenous; Kidney; Kidney Failure, Chroni | 1991 |
Pentamidine-induced torsades de pointes in a renal transplant recipient with Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Electrocardiography; Female; Humans; Immune Tolerance; Immunosup | 1990 |
Pentamidine pharmacokinetics in patients with AIDS with impaired renal function.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amidines; Child; Female; Half-Life; Humans; Infant; Infus | 1987 |