pentamidine has been researched along with Chagas Cardiomyopathy in 1 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Chagas Cardiomyopathy: A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "cruzi, the etiological agent of Chagas' disease." | 1.35 | In vitro and in vivo studies of the trypanocidal activity of a diarylthiophene diamidine against Trypanosoma cruzi. ( Batista, Dda G; Batista, MM; Boykin, DW; da Silva, CF; da Silva, PB; de Oliveira, GM; de Souza, EM; Meuser, AS; Shareef, AR; Soeiro, Mde N, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| da Silva, CF | 1 |
| Batista, MM | 1 |
| Batista, Dda G | 1 |
| de Souza, EM | 1 |
| da Silva, PB | 1 |
| de Oliveira, GM | 1 |
| Meuser, AS | 1 |
| Shareef, AR | 1 |
| Boykin, DW | 1 |
| Soeiro, Mde N | 1 |
1 other study available for pentamidine and Chagas Cardiomyopathy
| Article | Year |
|---|---|
In vitro and in vivo studies of the trypanocidal activity of a diarylthiophene diamidine against Trypanosoma cruzi.
Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Chlorocebus aethiops; Electrocardiography; Heart; Ma | 2008 |