pentamidine has been researched along with Candidiasis in 12 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Candidiasis: Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The in vitro interaction of pentamidine with ketoconazole and with itraconazole was studied with 10 strains of Candida albicans isolated from acquired immunodeficiency syndrome patients and one azole-resistant strain." | 3.68 | Effects of pentamidine alone and in combination with ketoconazole or itraconazole on the growth of Candida albicans. ( St-Germain, G, 1990) |
| "The test is applied on AIDS prophylaxis and paediatric trials." | 2.69 | Combining mortality and longitudinal measures in clinical trials. ( Finkelstein, DM; Schoenfeld, DA, 1999) |
| "The prevention of cerebral toxoplasmosis and of Pneumocystis carinii pneumonia is an essential objective in the management of patients infected with HIV." | 2.68 | Prevention of Pneumocystis carinii pneumonia and of cerebral toxoplasmosis by roxithromycin in HIV-infected patients. ( Carles, M; Dellamonica, P; Durant, J; Hazime, F; Pechere, JC, 1995) |
| "carinii prophylaxis before the onset of AIDS: Mycobacterium avium complex disease, which developed in 33." | 1.29 | Clinical manifestations of AIDS in the era of pneumocystis prophylaxis. Multicenter AIDS Cohort Study. ( Anderson, R; Bacellar, H; Detels, R; Hoover, DR; Kaslow, RA; Phair, J; Saah, AJ, 1993) |
| "The diagnosis of acquired immunodeficiency syndrome (AIDS) was suspected, although enzyme-linked immunosorbent assay (ELISA) and Western blot tests were both negative for human immunodeficiency virus (HIV) antibody." | 1.27 | Pediatric acquired immunodeficiency syndrome with negative human immunodeficiency virus antibody response by enzyme-linked immunosorbent assay and Western blot. ( Goetz, DW; Hall, SE; Harbison, RW; Reid, MJ, 1988) |
| "Chronic mucocutaneous candidiasis is a relatively uncommon form of candida infection, and can be found in patients with primary deficiencies of their immune systems." | 1.26 | An evolution of therapy for mucocutaneous candidiasis. ( Kornblut, AD, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (66.67) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SOLOTOROVSKY, M | 1 |
| IRONSON, EJ | 1 |
| GREGORY, FJ | 1 |
| WINSTEN, S | 1 |
| STENDERUP, A | 3 |
| BICHEL, J | 2 |
| KISSMEYER-NIELSEN, F | 1 |
| KISSMEYERNIELSEN, F | 1 |
| BEEKEN, E | 1 |
| IVADY, G | 1 |
| FRIEDRICH, E | 1 |
| Kornblut, AD | 1 |
| Durant, J | 1 |
| Hazime, F | 1 |
| Carles, M | 1 |
| Pechere, JC | 1 |
| Dellamonica, P | 1 |
| Hoover, DR | 1 |
| Saah, AJ | 1 |
| Bacellar, H | 1 |
| Phair, J | 1 |
| Detels, R | 1 |
| Anderson, R | 1 |
| Kaslow, RA | 1 |
| Finkelstein, DM | 1 |
| Schoenfeld, DA | 1 |
| Tóth, G | 1 |
| Miklós, G | 1 |
| Kerekes, A | 1 |
| Katona, J | 1 |
| Szarvas, D | 1 |
| St-Germain, G | 1 |
| Goetz, DW | 1 |
| Hall, SE | 1 |
| Harbison, RW | 1 |
| Reid, MJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 1 Safety Run-in Study and Phase 1b Randomized, Double Blinded, Placebo Controlled Trial[NCT05695521] | Phase 1 | 66 participants (Anticipated) | Interventional | 2023-04-03 | Recruiting | ||
| A Randomized Study of the MitraClip Device in Heart Failure Patients With Clinically Significant Functional Mitral Regurgitation[NCT01772108] | 42 participants (Actual) | Interventional | 2013-04-30 | Terminated (stopped due to As recruitment rate was lower than anticipated) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for pentamidine and Candidiasis
| Article | Year |
|---|---|
Prevention of Pneumocystis carinii pneumonia and of cerebral toxoplasmosis by roxithromycin in HIV-infected patients.
Topics: Adult; AIDS-Related Opportunistic Infections; Candidiasis; Digestive System; Drug Therapy, Combinati | 1995 |
Combining mortality and longitudinal measures in clinical trials.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candi | 1999 |
Combining mortality and longitudinal measures in clinical trials.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candi | 1999 |
Combining mortality and longitudinal measures in clinical trials.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candi | 1999 |
Combining mortality and longitudinal measures in clinical trials.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candi | 1999 |
10 other studies available for pentamidine and Candidiasis
| Article | Year |
|---|---|
Activity of certain diamidines against blastomycosis and Candida infection in mice.
Topics: Amidines; Animals; Blastomycosis; Candida; Candidiasis; Mice; Pentamidine; Stilbenes | 1954 |
Moniliasis treated with pentamidine.
Topics: Candidiasis; Humans; Pentamidine | 1956 |
Pentamidine by moniliasis.
Topics: Candidiasis; Humans; Pentamidine | 1956 |
[Moniliasis; clinical considerations].
Topics: Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antibiotics, Antitubercular; Candidiasis; Cortis | 1957 |
[Comparative studies on the efficacy of pentamidine, Solustibosan and Neostibosan against Candida albicans].
Topics: Amidines; Aniline Compounds; Antimony; Antimony Sodium Gluconate; Candida albicans; Candidiasis; Hum | 1960 |
An evolution of therapy for mucocutaneous candidiasis.
Topics: Amphotericin B; Antifungal Agents; Benzalkonium Compounds; Candida; Candidiasis; Candidiasis, Cutane | 1980 |
Clinical manifestations of AIDS in the era of pneumocystis prophylaxis. Multicenter AIDS Cohort Study.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Candidiasis; CD4-Positive | 1993 |
[Pentamidine treatment of conge nital generalized candidiasis].
Topics: Amidines; Amniotic Fluid; Candida albicans; Candidiasis; Humans; Infant, Newborn; Infant, Newborn, D | 1977 |
Effects of pentamidine alone and in combination with ketoconazole or itraconazole on the growth of Candida albicans.
Topics: Acquired Immunodeficiency Syndrome; Antifungal Agents; Candida albicans; Candidiasis; Drug Resistanc | 1990 |
Pediatric acquired immunodeficiency syndrome with negative human immunodeficiency virus antibody response by enzyme-linked immunosorbent assay and Western blot.
Topics: Acquired Immunodeficiency Syndrome; Antibodies, Viral; Candidiasis; Enzyme-Linked Immunosorbent Assa | 1988 |