pentamidine has been researched along with Cancer of Prostate in 2 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentamidine can efficiently suppress prostate cancer progression and may serve as a novel mitochondria-targeted therapeutic agent for prostate cancer." | 1.56 | Pentamidine inhibits prostate cancer progression via selectively inducing mitochondrial DNA depletion and dysfunction. ( Gao, WQ; Li, LF; Liu, L; Liu, Y; Tong, Y; Wang, F, 2020) |
| "Pentamidine is an aromatic diamine used for the treatment of human protozoa infections." | 1.37 | Pentamidine reduces expression of hypoxia-inducible factor-1α in DU145 and MDA-MB-231 cancer cells. ( Baek, WK; Jung, HJ; Park, JW; Suh, MH; Suh, SI, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, L | 1 |
| Wang, F | 1 |
| Tong, Y | 1 |
| Li, LF | 1 |
| Liu, Y | 1 |
| Gao, WQ | 1 |
| Jung, HJ | 1 |
| Suh, SI | 1 |
| Suh, MH | 1 |
| Baek, WK | 1 |
| Park, JW | 1 |
2 other studies available for pentamidine and Cancer of Prostate
| Article | Year |
|---|---|
Pentamidine inhibits prostate cancer progression via selectively inducing mitochondrial DNA depletion and dysfunction.
Topics: Animals; Cell Proliferation; DNA, Mitochondrial; DNA, Neoplasm; Humans; Male; Membrane Potential, Mi | 2020 |
Pentamidine reduces expression of hypoxia-inducible factor-1α in DU145 and MDA-MB-231 cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; | 2011 |