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pentamidine and Bronchial Spasm

pentamidine has been researched along with Bronchial Spasm in 16 studies

Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.

Research Excerpts

ExcerptRelevanceReference
"The frequent occurrence of bronchospasm due to aerosolized pentamidine (AP) may reduce delivery of drugs to distal airways and produce symptoms that limit therapy."9.07Prophylaxis of aerosolized pentamidine-induced bronchospasm: a symptom-based approach. ( Jensen, WA; Kagawa, FT; Kirsch, CM; McSharry, RJ, 1993)
"The frequent occurrence of bronchospasm due to aerosolized pentamidine (AP) may reduce delivery of drugs to distal airways and produce symptoms that limit therapy."5.07Prophylaxis of aerosolized pentamidine-induced bronchospasm: a symptom-based approach. ( Jensen, WA; Kagawa, FT; Kirsch, CM; McSharry, RJ, 1993)
"To assess the safety and efficacy of aerosol pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS)."5.07Aerosol pentamidine for secondary prophylaxis of AIDS-related Pneumocystis carinii pneumonia. A randomized, placebo-controlled study. ( Chan, CK; Falutz, JM; Fong, IW; Gervais, A; Hyland, RH; Lawson, LM; MacFadden, D; Montaner, JS; Rachlis, AR; Renzi, PM, 1991)
"The incidence of Pneumocystis carinii pneumonia (PCP) has been shown to be high posttransplantation in the absence of prophylaxis."1.29Utility of inhaled pentamidine prophylaxis in lung transplant recipients. ( Kass, RM; Koerner, SK; Nathan, SD; Ross, DJ; Zakowski, P, 1994)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's10 (62.50)18.2507
2000's0 (0.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Macesic, N1
Urbancic, K1
Ierino, F1
Grayson, ML1
Nathan, SD1
Ross, DJ1
Zakowski, P1
Kass, RM1
Koerner, SK1
McSharry, RJ1
Kirsch, CM1
Jensen, WA1
Kagawa, FT1
Pradalier, A1
Vincent, D1
Bouee, S1
Girard, PM1
Rawji, A1
Lee-Pack, LR2
Favell, K2
Chan, CK4
Chan, M1
Gearhart, MO1
Bhutani, MS1
Katzman, M1
Meade, W1
Iglar, K1
Rachlis, A1
Berger, P1
Doré, MF1
Bréchot, JM1
Orvoën-Frija, E1
Poubeau, P1
Rochemaure, J1
Montaner, JS1
Lawson, LM1
Gervais, A1
Hyland, RH1
Falutz, JM1
Renzi, PM1
MacFadden, D1
Rachlis, AR1
Fong, IW1
Chanez, P1
Bousquet, J1
Mauboussin, JM1
Godard, P1
Michel, FB1
Jesuthasan, AJ1
Datta, AK1
Hamilton, R1
Elliott, M1
Guz, A1
Weinberg, J1
Paton, WD1
Alston, TA1

Trials

4 trials available for pentamidine and Bronchial Spasm

ArticleYear
Prophylaxis of aerosolized pentamidine-induced bronchospasm: a symptom-based approach.
    The American journal of the medical sciences, 1993, Volume: 306, Issue:1

    Topics: Administration, Inhalation; Adult; Aerosols; AIDS-Related Opportunistic Infections; Bronchial Spasm;

1993
Acute pulmonary effects of three nebulizers for administering aerosol pentamidine: comparison of Parineb to Fisoneb and Respirgard II.
    Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine, 1996,Winter, Volume: 9, Issue:4

    Topics: Administration, Inhalation; Analysis of Variance; Antifungal Agents; Bronchial Spasm; Cross-Over Stu

1996
Aerosol pentamidine for secondary prophylaxis of AIDS-related Pneumocystis carinii pneumonia. A randomized, placebo-controlled study.
    Annals of internal medicine, 1991, Jun-01, Volume: 114, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Bronchial Spasm; Cough; Female; Follow-Up Studi

1991
Acute pulmonary effects of aerosolized pentamidine. A randomized controlled study. Toronto Aerosolized Pentamidine Study (TAPS) Group.
    Chest, 1990, Volume: 98, Issue:4

    Topics: Adult; Aerosols; Bronchial Spasm; Cough; Double-Blind Method; Female; Humans; Lung; Male; Pentamidin

1990

Other Studies

12 other studies available for pentamidine and Bronchial Spasm

ArticleYear
Is Aerosolized Pentamidine for Pneumocystis Pneumonia Prophylaxis in Renal Transplant Recipients Not as Safe as We Might Think?
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:4

    Topics: Adult; Aerosols; Antifungal Agents; Bronchial Spasm; Female; Humans; Kidney Transplantation; Lung; M

2016
Utility of inhaled pentamidine prophylaxis in lung transplant recipients.
    Chest, 1994, Volume: 105, Issue:2

    Topics: Administration, Inhalation; Aerosols; Bronchial Spasm; Bronchoscopy; Drug Hypersensitivity; Forced E

1994
[Bronchospasm of allergic mechanism caused by pentamidine isethionate aerosols].
    Presse medicale (Paris, France : 1983), 1993, Mar-27, Volume: 22, Issue:11

    Topics: Administration, Inhalation; Adult; Bronchial Spasm; Humans; Male; Pentamidine

1993
Lack of desensitization to aerosol pentamidine with long-term use.
    Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine, 1996,Summer, Volume: 9, Issue:2

    Topics: Administration, Inhalation; Adult; Aerosols; AIDS-Related Opportunistic Infections; Albuterol; Antif

1996
Intravenous pentamidine-induced bronchospasm.
    Chest, 1992, Volume: 102, Issue:6

    Topics: Adult; Albuterol; Bronchial Spasm; Diphenhydramine; HIV Seropositivity; Humans; Injections, Intraven

1992
High incidence of bronchospasm with regular administration of aerosolized pentamidine.
    Chest, 1992, Volume: 101, Issue:1

    Topics: Aerosols; Albuterol; Bronchial Spasm; Forced Expiratory Volume; HIV Infections; Humans; Pentamidine;

1992
Acute pulmonary effects of aerosolized pentamidine.
    Chest, 1991, Volume: 100, Issue:4

    Topics: Aerosols; Bronchial Spasm; Cough; Humans; Pentamidine; Pneumonia, Pneumocystis

1991
Bronchoconstriction and pentamidine.
    Lancet (London, England), 1989, Jun-10, Volume: 1, Issue:8650

    Topics: Amidines; Benzhydryl Compounds; Bronchial Spasm; Histamine H1 Antagonists; Humans; Pentamidine; Skin

1989
Aerosolised pentamidine.
    Lancet (London, England), 1989, Nov-25, Volume: 2, Issue:8674

    Topics: Adult; Aerosols; Bronchial Spasm; Female; Humans; Male; Pentamidine

1989
Aerosolised pentamidine.
    Lancet (London, England), 1987, Oct-24, Volume: 2, Issue:8565

    Topics: Aerosols; Amidines; Bronchial Spasm; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; Sodium Chlo

1987
Aerosolised pentamidine.
    Lancet (London, England), 1987, Nov-14, Volume: 2, Issue:8568

    Topics: Aerosols; Amidines; Bronchial Spasm; Humans; Pentamidine

1987
Inhibition of cholinesterases by pentamidine.
    Lancet (London, England), 1988, Dec-17, Volume: 2, Issue:8625

    Topics: Amidines; Bronchial Spasm; Cholinesterase Inhibitors; Humans; Pentamidine

1988