Page last updated: 2024-11-02

pentamidine and Babesia Infection

pentamidine has been researched along with Babesia Infection in 15 studies

Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

Research Excerpts

ExcerptRelevanceReference
"Control of bovine babesiosis has been hindered by the limited treatment selection for B."1.56Drug screening of food and drug administration-approved compounds against Babesia bovis in vitro. ( Benedicto, B; Beshbishy, AM; Galon, EM; Gao, Y; Guo, H; Igarashi, I; Ji, S; Lee, SH; Li, J; Li, Y; Liu, M; Moumouni, PFA; Nugraha, AB; Rizk, MA; Tumwebaze, MA; Xuan, X; Yokoyama, N, 2020)
" The LD50 of the liposome encapsulated diamidine administered intravenously and intramuscularly was for albino mice 52 and 6000 mg/kg, respectively whereas that of the free diamidine was 0."1.28[A liposomal form of diamidine: reduced toxicity]. ( Bogdanov, AA; Bolotin, IM; Georgiu, Kh; Klibanov, AL; Malyshev, SN; Stepanova, LP; Timofeev, BA; Torchilin, VP, 1991)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199010 (66.67)18.7374
1990's2 (13.33)18.2507
2000's0 (0.00)29.6817
2010's2 (13.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Li, Y1
Liu, M1
Rizk, MA1
Moumouni, PFA1
Lee, SH1
Galon, EM1
Guo, H1
Gao, Y1
Li, J1
Beshbishy, AM1
Nugraha, AB1
Ji, S1
Tumwebaze, MA1
Benedicto, B1
Yokoyama, N1
Igarashi, I1
Xuan, X1
ASHLEY, JN1
BERG, SS1
LUCAS, JM1
Hwang, SJ1
Yamasaki, M1
Nakamura, K1
Sasaki, N1
Murakami, M1
Wickramasekara Rajapakshage, BK1
Ohta, H1
Maede, Y1
Takiguchi, M1
Nehrbass-Stuedli, A1
Boykin, D1
Tidwell, RR1
Brun, R1
Löhr, FK1
Otieno, PS1
Gacanga, W1
Farwell, GE1
LeGrand, EK1
Cobb, CC1
Teutsch, SM2
Etkind, P1
Burwell, EL1
Sato, K1
Dana, MM1
Fleishman, PR1
Juranek, DD2
Francioli, PB1
Keithly, JS1
Jones, TC1
Brandstetter, RD1
Wolf, DJ1
Gray, JS1
Pudney, M1
Pipano, E1
Jeruham, I1
Frank, M1
Miller, LH1
Neva, FA1
Gill, F1
Timofeev, BA1
Bolotin, IM1
Stepanova, LP1
Bogdanov, AA1
Georgiu, Kh1
Malyshev, SN1
Klibanov, AL1
Torchilin, VP1
Raoult, D1
Soulayrol, L1
Toga, B1
Dumon, H1
Casanova, P1
Mehlhorn, H1
Raether, W1
Schein, E1
Weber, M1
Uphoff, M1

Other Studies

15 other studies available for pentamidine and Babesia Infection

ArticleYear
Drug screening of food and drug administration-approved compounds against Babesia bovis in vitro.
    Experimental parasitology, 2020, Volume: 210

    Topics: Animals; Antiprotozoal Agents; Babesia bovis; Babesiosis; Cattle; Cattle Diseases; Dogs; Doxorubicin

2020
3:3'-diamidinocarbanilide: a new drug active against Babesial infections.
    Nature, 1960, Feb-13, Volume: 185, Issue:4711

    Topics: Animals; Antiprotozoal Agents; Babesiosis; Cattle; Cattle Diseases; Mice; Pentamidine

1960
Development and characterization of a strain of Babesia gibsoni resistant to diminazene aceturate in vitro.
    The Journal of veterinary medical science, 2010, Volume: 72, Issue:6

    Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Cell Division; Clindamycin; Diminazene; Dog Dise

2010
Novel diamidines with activity against Babesia divergens in vitro and Babesia microti in vivo.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7

    Topics: Animals; Antiprotozoal Agents; Babesia; Babesia microti; Babesiosis; Benzimidazoles; Female; Furans;

2011
Therapy trial using betamethasone in addition to specific treatment with a diamidine and quinuronium derivate in cattle experimentally infected with Babesia bigemina.
    Bulletin of animal health and production in Africa. Bulletin des sante et production animales en Afrique, 1976, Volume: 24, Issue:2

    Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Betamethasone; Cattle; Cattle Diseases; Organ Sp

1976
Clinical observations on Babesia gibsoni and Babesia canis infections in dogs.
    Journal of the American Veterinary Medical Association, 1982, Mar-01, Volume: 180, Issue:5

    Topics: Animals; Babesiosis; Diminazene; Dog Diseases; Dogs; Erythrocytes; Female; Japan; Pentamidine

1982
Babesiosis in post-splenectomy hosts.
    The American journal of tropical medicine and hygiene, 1980, Volume: 29, Issue:5

    Topics: Animals; Babesiosis; Chloroquine; Female; Humans; Male; Massachusetts; Middle Aged; New York; Pentam

1980
Response of babesiosis to pentamidine therapy.
    Annals of internal medicine, 1981, Volume: 94, Issue:3

    Topics: Aged; Amidines; Animals; Babesia; Babesiosis; Female; Humans; Male; Middle Aged; Pain; Pentamidine;

1981
Babesiosis.
    Annals of internal medicine, 1981, Volume: 95, Issue:2

    Topics: Amidines; Animals; Babesiosis; Humans; Pentamidine

1981
Activity of atovaquone against Babesia microti in the Mongolian gerbil, Meriones unguiculatus.
    The Journal of parasitology, 1999, Volume: 85, Issue:4

    Topics: Acute Disease; Animals; Antiprotozoal Agents; Atovaquone; Babesiosis; Chronic Disease; Clindamycin;

1999
Pentamidine in chemoimmunisation of cattle against Babesia bigemina infection.
    Tropical animal health and production, 1979, Volume: 11, Issue:1

    Topics: Amidines; Animals; Babesiosis; Carrier State; Cattle; Cattle Diseases; Female; Immunization; Male; P

1979
Failure of chloroquine in human babesiosis (Babesia microti): case report and chemotherapeutic trials in hamsters.
    Annals of internal medicine, 1978, Volume: 88, Issue:2

    Topics: Animals; Babesiosis; Benzamidines; Chloroquine; Cricetinae; Drug Resistance; Humans; Male; Metronida

1978
[A liposomal form of diamidine: reduced toxicity].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1991, Volume: 36, Issue:9

    Topics: Animals; Babesiosis; Drug Carriers; Horses; Lethal Dose 50; Liposomes; Mice; Pentamidine; Sheep

1991
Babesiosis, pentamidine, and cotrimoxazole.
    Annals of internal medicine, 1987, Volume: 107, Issue:6

    Topics: Adult; Amidines; Babesiosis; Drug Combinations; Drug Therapy, Combination; Humans; Male; Pentamidine

1987
[Light and electron microscopy studies of the developmental cycle and effect of pentamidine on the morphology of intra-erythrocyte stages of Babesia microti].
    DTW. Deutsche tierarztliche Wochenschrift, 1986, Oct-08, Volume: 93, Issue:9

    Topics: Amidines; Animals; Babesia; Babesiosis; Cricetinae; Erythrocytes; Gerbillinae; Mesocricetus; Mice; M

1986