pentamidine has been researched along with Autoimmune Diabetes in 10 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twelve cases of diabetes mellitus following pentamidine isethionate ( Lomidine ) treatment for antimonial -resistant cases of kala-azar are reported." | 7.67 | Pentamidine-induced diabetes mellitus. ( Jha, TK; Sharma, VK, 1984) |
| "Twelve cases of diabetes mellitus following pentamidine isethionate ( Lomidine ) treatment for antimonial -resistant cases of kala-azar are reported." | 3.67 | Pentamidine-induced diabetes mellitus. ( Jha, TK; Sharma, VK, 1984) |
| " Two patients with advanced stages of the disease were treated with polychemotherapy (pentamidine and allopurinol) combined with recombinant human interferon-gamma (rIFN-gamma)." | 1.30 | The efficacy of pentamidine combined with allopurinol and immunotherapy for the treatment of patients with diffuse cutaneous leishmaniasis. ( Becker, I; Berzunza-Cruz, M; Dominguez, JS; Morales-Vargas, A; Perez-Montfort, R; Ruiz-Remigio, A; Salaiza-Suazo, N; Velasco-Castrejon, O; Volkow, P, 1999) |
| "Pentamidine is known to cause severe dysglycaemia by damaging beta-cell function of the pancreas." | 1.29 | Insulin-dependent diabetes mellitus following pentamidine therapy in a patient with AIDS. ( Bogner, JR; Goebel, FD; Liegl, U, 1994) |
| "Pentamidine which is an agent usually used to treat leishmaniasis and trypanosomiasis, but it is an alternative for P." | 1.28 | [Diabetes mellitus induced by pentamidine, without previous episodes of hypoglycemia, in patients with AIDS]. ( Caso, E; del Arco, C; García-Polo, I; Gómez-Pan, A; Noguerado, A; Santos, I, 1990) |
| " Dosage adjustment or alternative therapy should be considered with the onset of toxicity." | 1.28 | Insulin-dependent diabetes mellitus associated with pentamidine. ( Collins, J; Houk, JH; Pien, FD, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jha, TK | 1 |
| Sharma, VK | 1 |
| Blanc, MH | 1 |
| Liegl, U | 1 |
| Bogner, JR | 1 |
| Goebel, FD | 1 |
| Becker, I | 1 |
| Volkow, P | 1 |
| Velasco-Castrejon, O | 1 |
| Salaiza-Suazo, N | 1 |
| Berzunza-Cruz, M | 1 |
| Dominguez, JS | 1 |
| Morales-Vargas, A | 1 |
| Ruiz-Remigio, A | 1 |
| Perez-Montfort, R | 1 |
| Herrmann, BL | 1 |
| Saller, B | 1 |
| Sauer, J | 1 |
| Brockmeyer, N | 1 |
| Mann, K | 1 |
| Morin, D | 1 |
| Dumas, ML | 1 |
| Valette, H | 1 |
| Dumas, R | 1 |
| Millard, PS | 1 |
| van der Horst, C | 1 |
| Santos, I | 1 |
| del Arco, C | 1 |
| García-Polo, I | 1 |
| Noguerado, A | 1 |
| Caso, E | 1 |
| Gómez-Pan, A | 1 |
| Shen, M | 1 |
| Orwoll, ES | 1 |
| Conte, JE | 1 |
| Prince, MJ | 1 |
| Collins, J | 1 |
| Pien, FD | 1 |
| Houk, JH | 1 |
1 review available for pentamidine and Autoimmune Diabetes
| Article | Year |
|---|---|
[AIDS and diabetes].
Topics: Acquired Immunodeficiency Syndrome; Anti-Infective Agents; Antimetabolites; Antineoplastic Agents, H | 1995 |
9 other studies available for pentamidine and Autoimmune Diabetes
| Article | Year |
|---|---|
Pentamidine-induced diabetes mellitus.
Topics: Amidines; Diabetes Mellitus; Diabetes Mellitus, Type 1; Humans; Leishmaniasis, Visceral; Pentamidine | 1984 |
Insulin-dependent diabetes mellitus following pentamidine therapy in a patient with AIDS.
Topics: AIDS-Related Opportunistic Infections; Diabetes Mellitus, Type 1; Humans; Male; Middle Aged; Pentami | 1994 |
The efficacy of pentamidine combined with allopurinol and immunotherapy for the treatment of patients with diffuse cutaneous leishmaniasis.
Topics: Adult; Allopurinol; Animals; Antiprotozoal Agents; Combined Modality Therapy; Diabetes Mellitus, Typ | 1999 |
[26-year-old patient with cutaneous leishmaniasis and an initial diabetes mellitus manifestation].
Topics: Adult; Antiprotozoal Agents; Diabetes Mellitus, Type 1; Drug Administration Schedule; Female; Follow | 1999 |
[Transitory acute kidney insufficiency and insulin-dependent after treatment of kala-azar with pentamidine and N-methylglucamine antimony].
Topics: Acute Kidney Injury; Antimony; Antiprotozoal Agents; Child, Preschool; Diabetes Mellitus, Type 1; Hu | 1991 |
Reversible diabetes mellitus after intravenous pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Diabetes Mellitus, Type 1; Humans; Male; Middle A | 1991 |
[Diabetes mellitus induced by pentamidine, without previous episodes of hypoglycemia, in patients with AIDS].
Topics: Acquired Immunodeficiency Syndrome; Adult; Diabetes Mellitus, Type 1; Humans; Male; Pentamidine; Pne | 1990 |
Pentamidine-induced pancreatic beta-cell dysfunction.
Topics: Acquired Immunodeficiency Syndrome; Amidines; Chromatography, High Pressure Liquid; Diabetes Mellitu | 1989 |
Insulin-dependent diabetes mellitus associated with pentamidine.
Topics: Adult; Amidines; Diabetes Mellitus, Type 1; Humans; Male; Pentamidine; Pneumonia, Pneumocystis | 1989 |