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pentamidine and Asthma

pentamidine has been researched along with Asthma in 5 studies

Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Although TMP-SMX for PCP prophylaxis had to be discontinued in 43% of patients with connective tissue diseases, pentamidine and atovaquone were well tolerated."7.91Efficacies of atovaquone, pentamidine, and trimethoprim/sulfamethoxazole for the prevention of Pneumocystis jirovecii pneumonia in patients with connective tissue diseases. ( Asako, K; Kikuchi, H; Kitazawa, T; Kono, H; Ota, Y; Seo, K; Yoshino, Y, 2019)
"Although TMP-SMX for PCP prophylaxis had to be discontinued in 43% of patients with connective tissue diseases, pentamidine and atovaquone were well tolerated."3.91Efficacies of atovaquone, pentamidine, and trimethoprim/sulfamethoxazole for the prevention of Pneumocystis jirovecii pneumonia in patients with connective tissue diseases. ( Asako, K; Kikuchi, H; Kitazawa, T; Kono, H; Ota, Y; Seo, K; Yoshino, Y, 2019)
"Pneumothorax has been reported in several cases."1.37Fatal bilateral pneumothoraces following administration of aerosolised pentamidine. ( Green, A; Milne, N; Ong, BB, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kitazawa, T1
Seo, K1
Yoshino, Y1
Asako, K1
Kikuchi, H1
Kono, H1
Ota, Y1
Green, A1
Milne, N1
Ong, BB1
Lawrence, TE1
Millecchia, LL1
Fedan, JS1
Smaldone, GC1
Shelton, MJ1
Minor, JR1

Other Studies

5 other studies available for pentamidine and Asthma

ArticleYear
Efficacies of atovaquone, pentamidine, and trimethoprim/sulfamethoxazole for the prevention of Pneumocystis jirovecii pneumonia in patients with connective tissue diseases.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2019, Volume: 25, Issue:5

    Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antibi

2019
Fatal bilateral pneumothoraces following administration of aerosolised pentamidine.
    Journal of forensic and legal medicine, 2011, Volume: 18, Issue:7

    Topics: Administration, Inhalation; AIDS-Related Opportunistic Infections; Antifungal Agents; Asthma; Forens

2011
Fluticasone propionate and pentamidine isethionate reduce airway hyperreactivity, pulmonary eosinophilia and pulmonary dendritic cell response in a guinea pig model of asthma.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:1

    Topics: Androstadienes; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Dendritic Cells;

1998
Deposition patterns of nebulized drugs: is the pattern important?
    Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine, 1994, Volume: 7, Issue:Suppl 1

    Topics: Aerosols; Asthma; Cyclosporins; Cystic Fibrosis; Dose-Response Relationship, Drug; Gentamicins; Huma

1994
Aerosolized pentamidine in AIDS patients with asthma.
    American journal of hospital pharmacy, 1991, Volume: 48, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Asthma; Forced Expiratory Volume; Humans; Nebulizers and Vaporiz

1991