pentamidine has been researched along with Allergy, Drug in 14 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Only 5 of 37 patients started on trimethoprim-sulfamethoxazole were able to complete treatment; in 29 patients drug toxicity occurred and in 19 treatment was changed due to adverse reactions that included rash, fever, neutropenia, thrombocytopenia, and transaminase elevation." | 7.67 | Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome. ( Gordin, FM; Mills, J; Simon, GL; Wofsy, CB, 1984) |
| "Severe hemorrhagic pancreatitis developed in a patient with the acquired immunodeficiency syndrome (AIDS) during pentamidine isethionate treatment for Pneumocystis carinii pneumonia." | 7.67 | Pentamidine-associated fatal acute pancreatitis. ( el-Sadr, W; Rahal, JJ; Simberkoff, MS; Wolf, BZ; Zuger, A, 1986) |
| " Only 5 of 37 patients started on trimethoprim-sulfamethoxazole were able to complete treatment; in 29 patients drug toxicity occurred and in 19 treatment was changed due to adverse reactions that included rash, fever, neutropenia, thrombocytopenia, and transaminase elevation." | 3.67 | Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome. ( Gordin, FM; Mills, J; Simon, GL; Wofsy, CB, 1984) |
| "Severe hemorrhagic pancreatitis developed in a patient with the acquired immunodeficiency syndrome (AIDS) during pentamidine isethionate treatment for Pneumocystis carinii pneumonia." | 3.67 | Pentamidine-associated fatal acute pancreatitis. ( el-Sadr, W; Rahal, JJ; Simberkoff, MS; Wolf, BZ; Zuger, A, 1986) |
| "Management of patients with acquired immunodeficiency syndrome (AIDS) is complicated by a high frequency of adverse drug reactions to trimethoprim-sulfamethoxazole and pentamidine." | 3.67 | Management of drug allergy in patients with acquired immunodeficiency syndrome. ( Greenberger, PA; Patterson, R, 1987) |
| "In children with malignancy, TMP/SMX is well tolerated, but adverse reactions that necessitate discontinuation can occur." | 1.29 | Aerosolized pentamidine for the prevention of Pneumocystis carinii pneumonia in children with cancer intolerant or allergic to trimethoprim/sulfamethoxazole. ( Buchanan, GR; Cash, J; Mustafa, MM; Pappo, A; Winick, NJ, 1994) |
| "The incidence of Pneumocystis carinii pneumonia (PCP) has been shown to be high posttransplantation in the absence of prophylaxis." | 1.29 | Utility of inhaled pentamidine prophylaxis in lung transplant recipients. ( Kass, RM; Koerner, SK; Nathan, SD; Ross, DJ; Zakowski, P, 1994) |
| "To evaluate the adverse effects of intravenous pentamidine isethionate, a retrospective study was carried out over a four-year period." | 1.28 | Adverse effects associated with intravenous pentamidine isethionate as treatment of Pneumocystis carinii pneumonia in AIDS patients. ( Balslev, U; Nielsen, TL, 1992) |
| "Clinical features of 49 episodes of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome were compared with those of 39 episodes in patients with other immunosuppressive diseases." | 1.27 | Pneumocystis carinii pneumonia: a comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies. ( Hiemenz, JW; Honig, C; Kovacs, JA; Lane, HC; Longo, DL; Macher, AM; Murray, HW; Shelhamer, J; Stover, D; Urmacher, C, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 9 (64.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Altintas, G | 1 |
| Diken, AI | 1 |
| Diken, OE | 1 |
| Hanedan, O | 1 |
| Kucuker, SA | 1 |
| Gordin, FM | 1 |
| Simon, GL | 1 |
| Wofsy, CB | 1 |
| Mills, J | 1 |
| Kovacs, JA | 1 |
| Hiemenz, JW | 1 |
| Macher, AM | 1 |
| Stover, D | 1 |
| Murray, HW | 1 |
| Shelhamer, J | 1 |
| Lane, HC | 1 |
| Urmacher, C | 1 |
| Honig, C | 1 |
| Longo, DL | 1 |
| Combes, R | 1 |
| Bouvry, M | 1 |
| Mustafa, MM | 1 |
| Pappo, A | 1 |
| Cash, J | 1 |
| Winick, NJ | 1 |
| Buchanan, GR | 1 |
| Belsito, DV | 1 |
| Nathan, SD | 1 |
| Ross, DJ | 1 |
| Zakowski, P | 1 |
| Kass, RM | 1 |
| Koerner, SK | 1 |
| Korraa, H | 1 |
| Saadeh, C | 1 |
| Baum, CG | 1 |
| Sonnabend, JA | 1 |
| O'Sullivan, M | 1 |
| Balslev, U | 1 |
| Nielsen, TL | 1 |
| Gilquin, J | 1 |
| Blamoutier, J | 1 |
| Przepiorka, D | 1 |
| Selvaggi, K | 1 |
| Rosenzweig, PQ | 1 |
| Borochovitz, D | 1 |
| Taylor, D | 1 |
| Zuger, A | 1 |
| Wolf, BZ | 1 |
| el-Sadr, W | 1 |
| Simberkoff, MS | 1 |
| Rahal, JJ | 1 |
| Greenberger, PA | 1 |
| Patterson, R | 1 |
1 review available for pentamidine and Allergy, Drug
| Article | Year |
|---|---|
Options in the management of pneumonia caused by Pneumocystis carinii in patients with acquired immune deficiency syndrome and intolerance to trimethoprim/sulfamethoxazole.
Topics: Adrenal Cortex Hormones; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Ag | 1996 |
13 other studies available for pentamidine and Allergy, Drug
| Article | Year |
|---|---|
Inhaled pentamidine for Pneumocystis jiroveci prophylaxis in a heart transplant recipient with allergy for trimethoprim sulfamethoxazole.
Topics: Administration, Inhalation; Anti-Infective Agents; Antifungal Agents; Drug Administration Schedule; | 2011 |
Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Combinations; Drug Eruptions; Drug Hypersensitivity; | 1984 |
Pneumocystis carinii pneumonia: a comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Child; Drug Combinations; Drug Eruption | 1984 |
[Immuno-allergic pneumopathy after pentamidine aerosol].
Topics: Aerosols; Drug Hypersensitivity; Humans; Pentamidine; Pneumonia | 1995 |
Aerosolized pentamidine for the prevention of Pneumocystis carinii pneumonia in children with cancer intolerant or allergic to trimethoprim/sulfamethoxazole.
Topics: Adolescent; Aerosols; Child; Child, Preschool; Drug Hypersensitivity; Female; Humans; Male; Neoplasm | 1994 |
Contact urticaria from pentamidine isethionate.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Dermatitis, Occupa | 1993 |
Utility of inhaled pentamidine prophylaxis in lung transplant recipients.
Topics: Administration, Inhalation; Aerosols; Bronchial Spasm; Bronchoscopy; Drug Hypersensitivity; Forced E | 1994 |
Prophylaxis of AIDS-related Pneumocystis carinii pneumonia with aerosolized pentamidine in a patient with hypersensitivity to systemic pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aerosols; Dose-Response Relationship, Drug; Drug Hypersen | 1992 |
Adverse effects associated with intravenous pentamidine isethionate as treatment of Pneumocystis carinii pneumonia in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Drug Hypersensitivity; Humans; Injections, Intravenous; Pentamid | 1992 |
[Allergic keratoconjunctivitis caused by pentamidine isethionate].
Topics: Administration, Inhalation; Drug Hypersensitivity; Female; Humans; Keratoconjunctivitis; Middle Aged | 1992 |
Aerosolized pentamidine for prevention of Pneumocystis pneumonia after allogeneic marrow transplantation.
Topics: Administration, Intranasal; Aerosols; Bone Marrow Transplantation; Cost-Benefit Analysis; Drug Hyper | 1991 |
Pentamidine-associated fatal acute pancreatitis.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; Amidines; Drug Hypersensitivity; Hemorrhag | 1986 |
Management of drug allergy in patients with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Hypersensitivity; Humans; Injections, Intravenous; M | 1987 |