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pentamidine and Allergic Encephalomyelitis

pentamidine has been researched along with Allergic Encephalomyelitis in 1 studies

Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study is to investigate the possible role of a small molecule able to bind and inhibit S100B, pentamidine, in the modulation of disease progression in the relapsing-remitting experimental autoimmune encephalomyelitis mouse model of multiple sclerosis."7.96The S100B Inhibitor Pentamidine Ameliorates Clinical Score and Neuropathology of Relapsing-Remitting Multiple Sclerosis Mouse Model. ( Amadio, S; Casalbore, P; Clementi, ME; Di Sante, G; Michetti, F; Ria, F; Sampaolese, B; Valentini, M; Volonté, C, 2020)
" The aim of this study is to investigate the possible role of a small molecule able to bind and inhibit S100B, pentamidine, in the modulation of disease progression in the relapsing-remitting experimental autoimmune encephalomyelitis mouse model of multiple sclerosis."3.96The S100B Inhibitor Pentamidine Ameliorates Clinical Score and Neuropathology of Relapsing-Remitting Multiple Sclerosis Mouse Model. ( Amadio, S; Casalbore, P; Clementi, ME; Di Sante, G; Michetti, F; Ria, F; Sampaolese, B; Valentini, M; Volonté, C, 2020)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Di Sante, G1
Amadio, S1
Sampaolese, B1
Clementi, ME1
Valentini, M1
Volonté, C1
Casalbore, P1
Ria, F1
Michetti, F1

Other Studies

1 other study available for pentamidine and Allergic Encephalomyelitis

ArticleYear
The S100B Inhibitor Pentamidine Ameliorates Clinical Score and Neuropathology of Relapsing-Remitting Multiple Sclerosis Mouse Model.
    Cells, 2020, 03-18, Volume: 9, Issue:3

    Topics: Animals; Brain; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Ex

2020