pentamidine has been researched along with Abnormalities, Drug-Induced in 2 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentamidine was without teratogenic effects in rats when administered in doses similar to those recommended for adult humans; however, it appears to have an embryocidal effect when given in those same doses during embryogenesis." | 1.28 | Embryofetal effects of pentamidine isethionate administered to pregnant Sprague-Dawley rats. ( Bawdon, RE; Gilstrap, LC; Harstad, TW; Knoll, K; Little, BB; Roe, D, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moreno, JD | 1 |
| Minkoff, H | 1 |
| Harstad, TW | 1 |
| Little, BB | 1 |
| Bawdon, RE | 1 |
| Knoll, K | 1 |
| Roe, D | 1 |
| Gilstrap, LC | 1 |
2 other studies available for pentamidine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Human immunodeficiency virus infection during pregnancy.
Topics: Abnormalities, Drug-Induced; AIDS Serodiagnosis; Ethics, Medical; Female; HIV Infections; Humans; In | 1992 |
Embryofetal effects of pentamidine isethionate administered to pregnant Sprague-Dawley rats.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Female; Fetus; Maternal-Fetal Exchange; Pentam | 1990 |