pentamidine has been researched along with ARC in 5 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Excerpt | Relevance | Reference |
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"The efficacy and toxicity of pentamidine inhaled once a month to prevent Pneumocystis carinii pneumonia (PCP) was investigated in 102 patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC)." | 3.67 | Prevention of Pneumocystis carinii pneumonia by inhaled pentamidine. ( Chernoff, D; Conte, JE; Feigal, D; Golden, JA; Hollander, H, 1989) |
"89 patients were clinically in the AIDS stage and 33 in the AIDS-related complex (ARC) stage." | 1.28 | [The prevention of Pneumocystis carinii pneumonia by pentamidine inhalation]. ( Elsing, C; Erckenbrecht, J; Hengels, KH; Jablonowski, H; Strohmeyer, G, 1992) |
"In an open prospective study in the AIDS Outpatient Department of the Frankfurt University Clinic the efficacy of pentamidine aerosol at a dosage of 200 mg every 14 days in the primary and secondary prophylaxis of pneumocystis carinii pneumonia was tested." | 1.28 | [Prospective study of primary and secondary prevention of Pneumocystis carinii pneumonia with pentamidine aerosol]. ( Brodt, R; Gottstein, A; Helm, EB; Jacobi, V; Müller, H; Müller, R; Odewald, J; Rehmet, S; Staszewski, S; Trinder, S, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (20.00) | 18.7374 |
1990's | 4 (80.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Girard, PM | 1 |
Landman, R | 1 |
Gaudebout, C | 2 |
Olivares, R | 1 |
Saimot, AG | 1 |
Jelazko, P | 1 |
Certain, A | 1 |
Boué, F | 1 |
Bouvet, E | 1 |
Jablonowski, H | 1 |
Elsing, C | 1 |
Erckenbrecht, J | 1 |
Hengels, KH | 1 |
Strohmeyer, G | 1 |
Hirschel, B | 1 |
Lazzarin, A | 1 |
Chopard, P | 1 |
Opravil, M | 1 |
Furrer, HJ | 1 |
Rüttimann, S | 1 |
Vernazza, P | 1 |
Chave, JP | 1 |
Ancarani, F | 1 |
Gabriel, V | 1 |
Staszewski, S | 1 |
Trinder, S | 1 |
Gottstein, A | 1 |
Odewald, J | 1 |
Rehmet, S | 1 |
Brodt, R | 1 |
Jacobi, V | 1 |
Müller, R | 1 |
Müller, H | 1 |
Helm, EB | 1 |
Golden, JA | 1 |
Chernoff, D | 1 |
Hollander, H | 1 |
Feigal, D | 1 |
Conte, JE | 1 |
2 trials available for pentamidine and ARC
Article | Year |
---|---|
Dapsone-pyrimethamine compared with aerosolized pentamidine as primary prophylaxis against Pneumocystis carinii pneumonia and toxoplasmosis in HIV infection. The PRIO Study Group.
Topics: Adult; AIDS-Related Complex; AIDS-Related Opportunistic Infections; Dapsone; Drug Combinations; Ence | 1993 |
A controlled study of inhaled pentamidine for primary prevention of Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adolescent; Adult; Aerosols; Aged; A | 1991 |
3 other studies available for pentamidine and ARC
Article | Year |
---|---|
[The prevention of Pneumocystis carinii pneumonia by pentamidine inhalation].
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adolescent; Adult; AIDS-Related Comp | 1992 |
[Prospective study of primary and secondary prevention of Pneumocystis carinii pneumonia with pentamidine aerosol].
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; AIDS-Related Complex; Humans; | 1990 |
Prevention of Pneumocystis carinii pneumonia by inhaled pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; AIDS-Related Complex; Amidines; Coho | 1989 |