pentamidine has been researched along with AIDS Seroconversion in 41 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Four patients who coughed during AP administration were pretreated with 10 mg metaproterenol aerosol prior to a second inhalation of AP." | 9.07 | Bronchodilator pretreatment improves aerosol deposition uniformity in HIV-positive patients who cough while inhaling aerosolized pentamidine. ( Harrison, KS; Laube, BL, 1994) |
| "The frequent occurrence of bronchospasm due to aerosolized pentamidine (AP) may reduce delivery of drugs to distal airways and produce symptoms that limit therapy." | 9.07 | Prophylaxis of aerosolized pentamidine-induced bronchospasm: a symptom-based approach. ( Jensen, WA; Kagawa, FT; Kirsch, CM; McSharry, RJ, 1993) |
| "Four patients who coughed during AP administration were pretreated with 10 mg metaproterenol aerosol prior to a second inhalation of AP." | 5.07 | Bronchodilator pretreatment improves aerosol deposition uniformity in HIV-positive patients who cough while inhaling aerosolized pentamidine. ( Harrison, KS; Laube, BL, 1994) |
| "The frequent occurrence of bronchospasm due to aerosolized pentamidine (AP) may reduce delivery of drugs to distal airways and produce symptoms that limit therapy." | 5.07 | Prophylaxis of aerosolized pentamidine-induced bronchospasm: a symptom-based approach. ( Jensen, WA; Kagawa, FT; Kirsch, CM; McSharry, RJ, 1993) |
| "The development of PCP, transfusion requirements, monthly complete blood cell counts, serious adverse reactions and death were recorded." | 2.67 | Oral dapsone versus nebulized pentamidine for Pneumocystis carinii pneumonia prophylaxis: an open randomized prospective trial to assess efficacy and haematological toxicity. ( Hoy, JF; Kent, SJ; Lucas, CR; Pettinger, MB; Slavin, MA; Stewart, K, 1992) |
| "Use of pre-AIDS zidovudine and PCP prophylaxis was associated with significant reductions in rates of progression to AIDS at 6, 12, 18, and 24 months for participants starting with less than 350 CD4+ lymphocytes/microliter." | 2.67 | Effect of zidovudine and Pneumocystis carinii pneumonia prophylaxis on progression of HIV-1 infection to AIDS. The Multicenter AIDS Cohort Study. ( Detels, R; Graham, NM; Ho, M; Park, LP; Phair, JP; Saah, AJ; Vermund, SH; Zeger, SL, 1991) |
| "Pentamidine was well tolerated and produced no severe side effects." | 2.67 | [Randomized comparative study of secondary prevention of Pneumocystis carinii pneumonia in patients with acquired immunologic deficiency syndrome]. ( Elsing, C; Franke, M; Höffken, G; Lode, H; Noack, H; Petri, M; Ruhnke, M; Schrappe-Bächer, M; Stellbrink, HJ; Weiss, R, 1990) |
| "Pneumocystis carinii pneumonia is the most common life-threatening disease diagnosed in patients infected with the human immunodeficiency virus (HIV)." | 2.38 | Aerosolized pentamidine in HIV. Promising new treatment for Pneumocystis carinii pneumonia. ( Sarti, GM, 1989) |
| "Pentamidine was completed after 3 weeks, and antiretroviral treatment (ART) was initiated with dolutegravir 50 mg and Descovy HT (emtricitabine [200 mg] and tenofovir alafenamide fumarate [25 mg])." | 1.72 | Extrapulmonary pneumocystosis in an antiretroviral therapy-naïve, HIV-positive patient. ( Hasegawa, M; Hashimoto, M; Hashimoto, N; Ito, Y; Osugi, Y; Yano, K, 2022) |
| "Human African Trypanosomiasis, or African Sleeping Sickness, is a parasitic infection caused by Trypanosoma brucei (gambiense or rhodesiense), and one of the declared neglected tropical diseases." | 1.37 | Trypanosoma brucei infection in a HIV positive Ugandan male. ( Dill, EA; Kirkpatrick, BD; Renault, C, 2011) |
| "Spontaneous pneumothorax is a relatively frequent complication of human immunodeficiency virus (HIV) infection." | 1.30 | [Spontaneous pneumothorax associated with human immunodeficiency virus (HIV) infection]. ( Cifrián Martínez, JM; Fernández Rozas, SM; García Pérez, MM; Golpe Gómez, R; Jiménez Gómez, A; Mons Lera, R, 1998) |
| "To determine the use of AIDS drugs and therapies by populations with relatively good access to health care." | 1.29 | Use of therapeutic and prophylactic drugs for AIDS by homosexual and bisexual men in three US cities. ( Buchbinder, SP; Bush, TJ; Conley, LJ; Hershow, RC; Holmberg, SD; Judson, FN; Katz, MH; Penley, KA, 1993) |
| "89 patients were clinically in the AIDS stage and 33 in the AIDS-related complex (ARC) stage." | 1.28 | [The prevention of Pneumocystis carinii pneumonia by pentamidine inhalation]. ( Elsing, C; Erckenbrecht, J; Hengels, KH; Jablonowski, H; Strohmeyer, G, 1992) |
| "As pentamidine may cause pancreatitis and develop DIC, it is important that pancreatic enzymes should be carefully followed when this agent administrated." | 1.28 | [HIV-1 seropositive hemophilia A complicated by disseminated intravascular coagulation syndrome and acute pancreatitis during treatment of Pneumocystis carinii pneumonia]. ( Fukue, H; Koshihara, K; Matsumoto, K; Suzuki, T; Takahashi, Y; Tanaka, A; Tateyama, M; Yamagishi, T; Yorifuji, H; Yoshida, S, 1992) |
| "Whereas 50% of participants with AIDS and less than 200 CD4 were using both ZDV and AP, only 14% of those without AIDS but with less than 200 CD4 cells were using both." | 1.28 | Population-based estimates of zidovudine and aerosol pentamidine use in San Francisco: 1987-1989. ( Lang, W; Moss, A; Osmond, D; Samuel, M; Schrager, L; Winkelstein, W, 1991) |
| "Pneumothorax is a rare complication of Pn." | 1.28 | [Pneumothorax as a complication of Pneumocystis carinii pneumonia]. ( Battegay, M; Greminger, P; Lüthy, R, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (19.51) | 18.7374 |
| 1990's | 29 (70.73) | 18.2507 |
| 2000's | 1 (2.44) | 29.6817 |
| 2010's | 2 (4.88) | 24.3611 |
| 2020's | 1 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Hasegawa, M | 1 |
| Ito, Y | 1 |
| Osugi, Y | 1 |
| Hashimoto, M | 1 |
| Hashimoto, N | 1 |
| Yano, K | 1 |
| Rybniker, J | 1 |
| Goede, V | 1 |
| Mertens, J | 1 |
| Ortmann, M | 1 |
| Kulas, W | 1 |
| Kochanek, M | 1 |
| Benzing, T | 1 |
| Arribas, JR | 1 |
| Fätkenheuer, G | 1 |
| Dill, EA | 1 |
| Renault, C | 1 |
| Kirkpatrick, BD | 1 |
| López-Medrano, F | 1 |
| Costa, JR | 1 |
| Rodriguez-Peralto, JL | 1 |
| Aguado, JM | 1 |
| Harrison, KS | 1 |
| Laube, BL | 1 |
| Veyssier, P | 1 |
| Cevallos, R | 1 |
| Le Fouillé-Ribeyre, C | 1 |
| Geffray, L | 1 |
| Kaloustian, E | 1 |
| Farinotti, R | 1 |
| Luchon, L | 1 |
| Couderc, LJ | 1 |
| Stern, M | 1 |
| Friard, S | 1 |
| Caubarrere, I | 1 |
| Farquhar Zanetti, LA | 1 |
| Oliphant, CM | 1 |
| O'Riordan, TG | 1 |
| Baughman, RP | 1 |
| Dohn, MN | 1 |
| Smaldone, GC | 1 |
| Holmberg, SD | 1 |
| Conley, LJ | 1 |
| Buchbinder, SP | 1 |
| Judson, FN | 1 |
| Bush, TJ | 1 |
| Katz, MH | 1 |
| Penley, KA | 1 |
| Hershow, RC | 1 |
| McSharry, RJ | 1 |
| Kirsch, CM | 1 |
| Jensen, WA | 1 |
| Kagawa, FT | 1 |
| Tu, JV | 1 |
| Biem, HJ | 1 |
| Detsky, AS | 1 |
| O'Doherty, MJ | 2 |
| Thomas, SH | 1 |
| Page, CJ | 1 |
| Blower, PJ | 1 |
| Bateman, NT | 2 |
| Nunan, TO | 2 |
| Gaur, S | 1 |
| Rosenthal, S | 1 |
| Dadhania, J | 1 |
| Lupski, D | 1 |
| Mascarhenas, M | 1 |
| Amenta, PS | 1 |
| Bharucha, N | 1 |
| Cappell, MS | 1 |
| Read, CA | 1 |
| Cerrone, F | 1 |
| Busseniers, AE | 1 |
| Waldhorn, RE | 1 |
| Lavelle, JP | 1 |
| Pierce, PF | 1 |
| Golpe Gómez, R | 1 |
| Cifrián Martínez, JM | 1 |
| Fernández Rozas, SM | 1 |
| García Pérez, MM | 1 |
| Mons Lera, R | 1 |
| Jiménez Gómez, A | 1 |
| Wei, CC | 1 |
| Pack, LL | 1 |
| Chan, CK | 1 |
| Jablonowski, H | 1 |
| Elsing, C | 2 |
| Erckenbrecht, J | 1 |
| Hengels, KH | 1 |
| Strohmeyer, G | 1 |
| Suzuki, T | 1 |
| Takahashi, Y | 1 |
| Yoshida, S | 1 |
| Yamagishi, T | 1 |
| Tateyama, M | 1 |
| Tanaka, A | 1 |
| Koshihara, K | 1 |
| Matsumoto, K | 1 |
| Fukue, H | 1 |
| Yorifuji, H | 1 |
| Gearhart, MO | 1 |
| Bhutani, MS | 1 |
| Slavin, MA | 1 |
| Hoy, JF | 1 |
| Stewart, K | 1 |
| Pettinger, MB | 1 |
| Lucas, CR | 1 |
| Kent, SJ | 1 |
| Seligmann, M | 1 |
| Bálint, B | 1 |
| Kraszkó, P | 1 |
| Cuthbert, AC | 1 |
| Wright, D | 1 |
| McVerry, BA | 1 |
| Lang, W | 1 |
| Osmond, D | 1 |
| Samuel, M | 1 |
| Moss, A | 1 |
| Schrager, L | 1 |
| Winkelstein, W | 1 |
| Graham, NM | 1 |
| Zeger, SL | 1 |
| Park, LP | 1 |
| Phair, JP | 1 |
| Detels, R | 1 |
| Vermund, SH | 1 |
| Ho, M | 1 |
| Saah, AJ | 1 |
| Lortholary, O | 1 |
| Caumes, E | 1 |
| Valentin, MA | 1 |
| Katlama, C | 1 |
| Danis, M | 1 |
| Gentilini, M | 1 |
| Foster, RE | 1 |
| Lowder, CY | 1 |
| Meisler, DM | 1 |
| Huang, SS | 1 |
| Longworth, DL | 1 |
| Hirschel, B | 1 |
| Lazzarin, A | 1 |
| Chopard, P | 1 |
| Opravil, M | 1 |
| Furrer, HJ | 1 |
| Rüttimann, S | 1 |
| Vernazza, P | 1 |
| Chave, JP | 1 |
| Ancarani, F | 1 |
| Gabriel, V | 1 |
| Minkoff, HL | 1 |
| Moreno, JD | 1 |
| Höffken, G | 1 |
| Ruhnke, M | 1 |
| Franke, M | 1 |
| Schrappe-Bächer, M | 1 |
| Stellbrink, HJ | 1 |
| Weiss, R | 1 |
| Noack, H | 1 |
| Petri, M | 1 |
| Lode, H | 1 |
| Berman, SM | 1 |
| Shah, B | 1 |
| Wyle, FA | 1 |
| Dacosta-Iyer, M | 1 |
| McRae, DM | 1 |
| Nathwani, D | 1 |
| Green, ST | 1 |
| Atkinson, J | 1 |
| Kotkiewicz, C | 1 |
| Herer, B | 1 |
| Chinet, T | 1 |
| Labrune, S | 1 |
| Collignon, MA | 1 |
| Chretien, J | 1 |
| Huchon, G | 1 |
| Simonds, AK | 1 |
| Newman, SP | 1 |
| Johnson, MA | 1 |
| Talaee, N | 1 |
| Lee, CA | 1 |
| Clarke, SW | 1 |
| Sarti, GM | 1 |
| Battegay, M | 1 |
| Greminger, P | 1 |
| Lüthy, R | 1 |
| Thomas, S | 1 |
| Page, C | 1 |
| Barlow, D | 1 |
| Bradbeer, C | 1 |
3 reviews available for pentamidine and AIDS Seroconversion
| Article | Year |
|---|---|
Treatment of visceral leishmaniasis with intravenous pentamidine and oral fluconazole in an HIV-positive patient with chronic renal failure--a case report and brief review of the literature.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Drug Therapy, Com | 2010 |
Disseminated Pneumocystis carinii in a patient receiving aerosolized pentamidine prophylaxis.
Topics: Aerosols; HIV Seropositivity; Humans; Liver; Male; Middle Aged; Necrosis; Pentamidine; Pneumonia, Pn | 1990 |
Aerosolized pentamidine in HIV. Promising new treatment for Pneumocystis carinii pneumonia.
Topics: Aerosols; Amidines; Animals; Anti-Infective Agents; Child; Drug Combinations; Female; HIV Seropositi | 1989 |
7 trials available for pentamidine and AIDS Seroconversion
| Article | Year |
|---|---|
Bronchodilator pretreatment improves aerosol deposition uniformity in HIV-positive patients who cough while inhaling aerosolized pentamidine.
Topics: Adult; Aerosols; Cough; Female; Gamma Cameras; HIV Seropositivity; Humans; Lung; Male; Metaprotereno | 1994 |
Prophylaxis of aerosolized pentamidine-induced bronchospasm: a symptom-based approach.
Topics: Administration, Inhalation; Adult; Aerosols; AIDS-Related Opportunistic Infections; Bronchial Spasm; | 1993 |
Oral dapsone versus nebulized pentamidine for Pneumocystis carinii pneumonia prophylaxis: an open randomized prospective trial to assess efficacy and haematological toxicity.
Topics: Administration, Intranasal; Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Bloo | 1992 |
Effect of zidovudine and Pneumocystis carinii pneumonia prophylaxis on progression of HIV-1 infection to AIDS. The Multicenter AIDS Cohort Study.
Topics: Acquired Immunodeficiency Syndrome; Aerosols; CD4-Positive T-Lymphocytes; Evaluation Studies as Topi | 1991 |
A controlled study of inhaled pentamidine for primary prevention of Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adolescent; Adult; Aerosols; Aged; A | 1991 |
[Randomized comparative study of secondary prevention of Pneumocystis carinii pneumonia in patients with acquired immunologic deficiency syndrome].
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Female; HIV Seropositivity; H | 1990 |
Simple nebuliser modification to enhance alveolar deposition of pentamidine.
Topics: Administration, Inhalation; Clinical Trials as Topic; Equipment Design; HIV Seropositivity; Nebulize | 1989 |
31 other studies available for pentamidine and AIDS Seroconversion
| Article | Year |
|---|---|
Extrapulmonary pneumocystosis in an antiretroviral therapy-naïve, HIV-positive patient.
Topics: HIV Infections; HIV Seropositivity; Humans; Male; Pentamidine; Pneumocystis carinii; Pneumonia, Pneu | 2022 |
Trypanosoma brucei infection in a HIV positive Ugandan male.
Topics: Adult; Animals; Fatal Outcome; HIV Seropositivity; Humans; Male; Pentamidine; Trypanocidal Agents; T | 2011 |
An HIV-positive man with tattoo induration.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Animals; Antiprotozoal Agents; Biopsy, Needle | 2007 |
Safety of pentamidine prophylaxis for Pneumocystis carinii pneumonia on the endocrine pancreatic function in HIV patients.
Topics: Adult; Aerosols; AIDS-Related Opportunistic Infections; HIV Infections; HIV Seropositivity; Humans; | 1994 |
[Pulmonary pneumocystosis revealing HIV infection].
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Female; HIV Infect | 1994 |
Pentamidine-induced torsades de pointes.
Topics: Female; Fever of Unknown Origin; HIV Seropositivity; Humans; Middle Aged; Pentamidine; Pneumonia, Pn | 1994 |
Lobar pentamidine levels and Pneumocystis carinii pneumonia following aerosolized pentamidine.
Topics: Adult; Aerosols; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Colony Count, M | 1994 |
Use of therapeutic and prophylactic drugs for AIDS by homosexual and bisexual men in three US cities.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antiviral Agents; Bisexua | 1993 |
Bronchoscopy versus empirical therapy in HIV-infected patients with presumptive Pneumocystis carinii pneumonia. A decision analysis.
Topics: AIDS-Related Opportunistic Infections; Biopsy; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoscopy; | 1993 |
Disposition of nebulized pentamidine measured using the direct radiolabel 123I-iodopentamidine.
Topics: Administration, Inhalation; Adult; HIV Seropositivity; Humans; Iodine Radioisotopes; Isotope Labelin | 1993 |
Cholestatic giant cell hepatitis associated with ultrastructural evidence of intrahepatic retroviral infection in a human immunodeficiency virus-seropositive infant.
Topics: AIDS-Related Opportunistic Infections; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; | 1993 |
Differential lobe lavage for diagnosis of acute Pneumocystis carinii pneumonia in patients receiving prophylactic aerosolized pentamidine therapy.
Topics: Acute Disease; Adult; Aerosols; Biopsy; Bronchi; Bronchoalveolar Lavage Fluid; HIV Seropositivity; H | 1993 |
[Spontaneous pneumothorax associated with human immunodeficiency virus (HIV) infection].
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Drainage; Female; HIV Infection | 1998 |
Effects of long-term aerosol pentamidine for Pneumocystis carinii prophylaxis on pulmonary function.
Topics: Adult; Aerosols; AIDS-Related Opportunistic Infections; Antifungal Agents; Female; HIV Seropositivit | 1998 |
[The prevention of Pneumocystis carinii pneumonia by pentamidine inhalation].
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adolescent; Adult; AIDS-Related Comp | 1992 |
[HIV-1 seropositive hemophilia A complicated by disseminated intravascular coagulation syndrome and acute pancreatitis during treatment of Pneumocystis carinii pneumonia].
Topics: Adolescent; AIDS-Related Opportunistic Infections; Disseminated Intravascular Coagulation; Hemophili | 1992 |
Intravenous pentamidine-induced bronchospasm.
Topics: Adult; Albuterol; Bronchial Spasm; Diphenhydramine; HIV Seropositivity; Humans; Injections, Intraven | 1992 |
[What attitude to take in symptomless HIV infection?].
Topics: CD4 Antigens; HIV Seropositivity; Humans; Lymphocytes; Opportunistic Infections; Pentamidine; Pneumo | 1992 |
[Pneumocystis carinii pneumonia in a HIV-positive patient].
Topics: Acquired Immunodeficiency Syndrome; Adult; Bronchoalveolar Lavage Fluid; HIV Infections; HIV Seropos | 1992 |
Pneumothorax in pentamidine-treated haemophiliacs.
Topics: Hemophilia A; HIV Seropositivity; Humans; Pentamidine; Pneumonia, Pneumocystis; Pneumothorax | 1991 |
Population-based estimates of zidovudine and aerosol pentamidine use in San Francisco: 1987-1989.
Topics: Acquired Immunodeficiency Syndrome; Aerosols; CD4-Positive T-Lymphocytes; Cohort Studies; Drug Thera | 1991 |
[Cardiac complications of pentamidine isethionate. Report of a case].
Topics: Adult; HIV Seropositivity; Humans; Male; Pentamidine; Torsades de Pointes | 1991 |
Presumed Pneumocystis carinii choroiditis. Unifocal presentation, regression with intravenous pentamidine, and choroiditis recurrence.
Topics: Acquired Immunodeficiency Syndrome; Administration, Inhalation; Adult; Choroiditis; Eye Infections, | 1991 |
Drug prophylaxis for human immunodeficiency virus-infected pregnant women: ethical considerations.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antibodies, Anti-Idiotypic; Antigens, CD; CD4 Immunoadhes | 1990 |
Aerosolized pentamidine prophylaxis in the prison setting.
Topics: Adult; Aerosols; HIV Seropositivity; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; Prisoners | 1990 |
More on the expanded use of aerosolized pentamidine.
Topics: Acquired Immunodeficiency Syndrome; Aerosols; HIV Infections; HIV Seropositivity; Humans; Pentamidin | 1989 |
Pancreatitis associated with pentamidine by aerosol.
Topics: Adult; Aerosols; Amidines; Female; HIV Seropositivity; Humans; Male; Middle Aged; Pancreatitis; Pent | 1989 |
[Pneumothorax as a complication of Pneumocystis carinii pneumonia].
Topics: Adult; Female; HIV Seropositivity; Humans; Pentamidine; Pneumonia, Pneumocystis; Pneumothorax; Radio | 1989 |
Differences in relative efficiency of nebulisers for pentamidine administration.
Topics: Amidines; HIV Seropositivity; Humans; Male; Nebulizers and Vaporizers; Pentamidine; Pneumonia, Pneum | 1988 |
Fansidar-associated fatal reaction in an HIV-infected man.
Topics: Drug Combinations; Drug Therapy, Combination; HIV Seropositivity; Homosexuality; Humans; Male; Middl | 1988 |
Leads from the MMWR. Fansidar-associated fatal reaction in an HIV-infected man.
Topics: Drug Combinations; Drug Therapy, Combination; HIV Seropositivity; Homosexuality; Humans; Male; Middl | 1988 |