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pentachlorophenol and Porphyria

pentachlorophenol has been researched along with Porphyria in 15 studies

PENTA: structure given in first source

Research Excerpts

ExcerptRelevanceReference
" It has been found that under these conditions the active porphyrin uptake process, which is driven by the K+ transmembrane gradient, is maximally inhibited in the presence of pentachlorophenol at a concentration similar to that found in vivo in the hexachlorobenzene experimental porphyria."7.67The effect of iron overload on the mitochondrial porphyrin level in the hexachlorobenzene induced experimental porphyria. ( Ceccarelli, D; Masini, A; Muscatello, U; Trenti, T, 1988)
"Hexachlorobenzene feeding to rats for 60 days to induce experimental porphyria resulted in partial and constant uncoupling of oxidative phosphorylation of liver mitochondria from the early phase (i."7.67The role of pentachlorophenol in causing mitochondrial derangement in hexachlorobenzene induced experimental porphyria. ( Ceccarelli-Stanzani, D; Masini, A; Tomasi, A; Trenti, T; Ventura, E, 1985)
"Male and female F 344 rats were dosed every other day for 103 days with 50 mumole of hexachlorobenzene (HCB)/kg."5.26Sex differences in the metabolism of hexachlorobenzene by rats and the development of porphyria in females. ( Rizzardini, M; Smith, AG, 1982)
"The relation between the major toxic effect of hexachlorobenzene, hepatic porphyria, and its oxidative biotransformation was studied in vivo, by observing the effect of modulating its biotransformation on the expression of porphyria."3.67The relation between the oxidative biotransformation of hexachlorobenzene and its porphyrinogenic activity. ( Bessems, JG; Geesink, G; Hendriks, W; Müller, F; van Bladeren, PJ; van Ommen, B, 1989)
" It has been found that under these conditions the active porphyrin uptake process, which is driven by the K+ transmembrane gradient, is maximally inhibited in the presence of pentachlorophenol at a concentration similar to that found in vivo in the hexachlorobenzene experimental porphyria."3.67The effect of iron overload on the mitochondrial porphyrin level in the hexachlorobenzene induced experimental porphyria. ( Ceccarelli, D; Masini, A; Muscatello, U; Trenti, T, 1988)
"Hexachlorobenzene feeding to rats for 60 days to induce experimental porphyria resulted in partial and constant uncoupling of oxidative phosphorylation of liver mitochondria from the early phase (i."3.67The role of pentachlorophenol in causing mitochondrial derangement in hexachlorobenzene induced experimental porphyria. ( Ceccarelli-Stanzani, D; Masini, A; Tomasi, A; Trenti, T; Ventura, E, 1985)
"In answering the question as to what role possible metabolites of hexachlorobenzene play in the procreation of toxic hexachlorobenzene porphyria in rats, both pure hexachlorobenzene and different mixtures were fed to them."3.66[The effect of some hexachlorobenzene catabolites on the porphyrin metabolism of rats (author's transl)]. ( Kószó, F; Siklósi, C; Simon, N, 1981)
"Pentachlorophenol (PCP) is a pesticide that was once widely used for wood preservation."1.30A morbidity study of former pentachlorophenol-production workers. ( Ellefson, R; Furner, S; Haselhorst, B; Hryhorczuk, DO; Oleske, D; Persky, V; Wallace, WH; Webster, JR; Zugerman, C, 1998)
"Male and female F 344 rats were dosed every other day for 103 days with 50 mumole of hexachlorobenzene (HCB)/kg."1.26Sex differences in the metabolism of hexachlorobenzene by rats and the development of porphyria in females. ( Rizzardini, M; Smith, AG, 1982)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199013 (86.67)18.7374
1990's2 (13.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Graef, V1
Golf, SW1
Goerz, G2
Bańkowska, J1
Rizzardini, M1
Smith, AG1
Siklósi, C1
Simon, N1
Kószó, F1
Debets, FM1
Strik, JJ1
Olie, K1
Hryhorczuk, DO1
Wallace, WH1
Persky, V1
Furner, S1
Webster, JR1
Oleske, D1
Haselhorst, B1
Ellefson, R1
Zugerman, C1
Jirásek, L2
Kalenský, J2
Kubec, K2
Pazderová, J1
Lukás, E1
Vizethum, W1
Bolsen, K1
Krieg, T1
Lissner, R1
Goldstein, JA1
Friesen, M1
Linder, RE1
Hickman, P1
Hass, JR1
Bergman, H1
Ríos de Molina, MC1
Billi de Catabbi, S1
San Martín de Viale, LC1
van Ommen, B1
Hendriks, W1
Bessems, JG1
Geesink, G1
Müller, F1
van Bladeren, PJ1
Masini, A3
Trenti, T3
Ceccarelli, D2
Muscatello, U1
Ventura, E2
Ceccarelli-Stanzani, D1
Tomasi, A1

Other Studies

15 other studies available for pentachlorophenol and Porphyria

ArticleYear
The involvement of porphyrogenic steroids in the development of experimental porphyria.
    Experientia, 1980, Sep-15, Volume: 36, Issue:9

    Topics: 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Chlorobenzenes; Chl

1980
[Hepatotoxicity of selected polychlorinated aromatic hydrocarbons].
    Roczniki Panstwowego Zakladu Higieny, 1982, Volume: 33, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chlorophenols; Dioxins; Hexachlorob

1982
Sex differences in the metabolism of hexachlorobenzene by rats and the development of porphyria in females.
    Biochemical pharmacology, 1982, Nov-15, Volume: 31, Issue:22

    Topics: Animals; Bile; Chlorobenzenes; Diethylstilbestrol; Female; Hexachlorobenzene; Liver; Male; Pentachlo

1982
[The effect of some hexachlorobenzene catabolites on the porphyrin metabolism of rats (author's transl)].
    Dermatosen in Beruf und Umwelt. Occupation and environment, 1981, Volume: 29, Issue:2

    Topics: Animals; Chloranil; Chlorobenzenes; Hexachlorobenzene; Pentachlorophenol; Porphyrias; Porphyrins; Ra

1981
Effects of pentachlorophenol on rat liver changes induced by hexachlorobenzene, with special reference to porphyria, and alterations in mixed function oxygenases.
    Toxicology, 1980, Volume: 15, Issue:3

    Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chlorophenols; Female;

1980
A morbidity study of former pentachlorophenol-production workers.
    Environmental health perspectives, 1998, Volume: 106, Issue:7

    Topics: Acne Vulgaris; Adult; Aged; Aged, 80 and over; Chemical Industry; Databases, Factual; Environmental

1998
[Chloracne, porphyria cutanea tarda, and other poisonings due to the herbicides].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1976, Volume: 27, Issue:7

    Topics: 2,4,5-Trichlorophenoxyacetic Acid; Acne Vulgaris; Dioxins; Herbicides; Humans; Lipid Metabolism; Mal

1976
[Hexachlorbenzene (HCB) induced porphyria in rats. Influence of HCB-metabolites on the biosynthesis of heme (author's transl)].
    Archives of dermatological research, 1978, Nov-10, Volume: 263, Issue:2

    Topics: Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Female; Hexachlorobenzene; Pentachloropheno

1978
Effects of pentachlorophenol on hepatic drug-metabolizing enzymes and porphyria related to contamination with chlorinated dibenzo-p-dioxins and dibenzofurans.
    Biochemical pharmacology, 1977, Sep-01, Volume: 26, Issue:17

    Topics: Animals; Benzofurans; Body Weight; Chlorophenols; Diet; Dioxins; Drug Contamination; Female; Liver;

1977
Liver ferrochelatase from normal and hexachlorobenzene porphyric rats. Mechanism of drug action.
    The International journal of biochemistry, 1991, Volume: 23, Issue:7-8

    Topics: Animals; Binding Sites; Chromatography, Gel; Copper; Copper Sulfate; Female; Ferrochelatase; Heme; H

1991
The relation between the oxidative biotransformation of hexachlorobenzene and its porphyrinogenic activity.
    Toxicology and applied pharmacology, 1989, Sep-15, Volume: 100, Issue:3

    Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Cytochrome P-450

1989
The effect of iron overload on the mitochondrial porphyrin level in the hexachlorobenzene induced experimental porphyria.
    Biochemical and biophysical research communications, 1988, Feb-29, Volume: 151, Issue:1

    Topics: Animals; Cell Membrane Permeability; Chlorobenzenes; Female; Hexachlorobenzene; Iron; Liver; Mitocho

1988
Porphyrins and pentachlorophenol in rat-liver mitochondria in hexachlorobenzene-induced porphyria.
    IARC scientific publications, 1986, Issue:77

    Topics: Animals; Chlorobenzenes; Chlorophenols; Female; Hexachlorobenzene; Mitochondria, Liver; Pentachlorop

1986
The role of pentachlorophenol in causing mitochondrial derangement in hexachlorobenzene induced experimental porphyria.
    Biochemical pharmacology, 1985, Apr-15, Volume: 34, Issue:8

    Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Chlorophenols; F

1985
[Acne chlorina and porphyria cutanea tarda during the manufacturing of herbicides].
    Ceskoslovenska dermatologie, 1973, Volume: 48, Issue:5

    Topics: Acne Vulgaris; Adolescent; Adult; Environmental Exposure; Female; Herbicides; Humans; Male; Middle A

1973