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pentachlorophenol and Hemorrhage

pentachlorophenol has been researched along with Hemorrhage in 5 studies

PENTA: structure given in first source

Hemorrhage: Bleeding or escape of blood from a vessel.

Research Excerpts

ExcerptRelevanceReference
" It strongly inhibited thrombus formation in an experimental model of thromboplastin-induced venous thrombosis in rats (intravenously) and rabbits (subcutaneously) (ED50 values were 25."3.69Biochemical and pharmacological properties of SANORG 32701. Comparison with the "synthetic pentasaccharide' (SR 90107/ORG 31540) and standard heparin. ( Bernat, A; Hérault, JP; Herbert, JM; Lormeau, JC; Meuleman, DG; Petitou, M; van Amsterdam, RG; Vogel, GM, 1996)
"Venous thromboembolism is a frequent complication of total hip replacement."2.70A synthetic pentasaccharide for the prevention of deep-vein thrombosis after total hip replacement. ( Gallus, AS; Hoek, JA; Turpie, AG, 2001)
" administration, as expected because of the approximately 100% bioavailability of the anti-Xa activity after s."1.28Pharmacological profile of the chemically synthesized antithrombin III binding fragment of heparin (pentasaccharide) in rats. ( Hobbelen, PM; Meuleman, DG; Moelker, HC; van Boeckel, CA; van Dinther, TG; Vogel, GM, 1990)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Herbert, JM3
Hérault, JP1
Bernat, A3
van Amsterdam, RG1
Vogel, GM2
Lormeau, JC1
Petitou, M1
Meuleman, DG2
Hoffmann, P2
Savi, P1
Lale, A1
Turpie, AG1
Gallus, AS1
Hoek, JA1
Hobbelen, PM1
van Dinther, TG1
van Boeckel, CA1
Moelker, HC1

Trials

1 trial available for pentachlorophenol and Hemorrhage

ArticleYear
A synthetic pentasaccharide for the prevention of deep-vein thrombosis after total hip replacement.
    The New England journal of medicine, 2001, Mar-01, Volume: 344, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Dose-Res

2001

Other Studies

4 other studies available for pentachlorophenol and Hemorrhage

ArticleYear
Biochemical and pharmacological properties of SANORG 32701. Comparison with the "synthetic pentasaccharide' (SR 90107/ORG 31540) and standard heparin.
    Circulation research, 1996, Volume: 79, Issue:3

    Topics: Animals; Anticoagulants; Electric Stimulation; Factor Xa Inhibitors; Fibrinogen; Fibrinolytic Agents

1996
Antagonism of SR 90107A/Org 31540-induced bleeding by protamine sulfate in rats and mice.
    Thrombosis and haemostasis, 1996, Volume: 76, Issue:5

    Topics: Animals; Bleeding Time; Factor Xa Inhibitors; Fibrinolytic Agents; Hemorrhage; Heparin; Heparin Anta

1996
The antithrombotic efficacy of the GP IIb/IIIa antagonist SR121787 is potentiated by antithrombin-dependent factor Xa inhibition without an increase in the bleeding risk in the rabbit.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:4

    Topics: Animals; Anticoagulants; Antithrombins; Benzylamines; Carotid Arteries; Disease Models, Animal; Drug

1999
Pharmacological profile of the chemically synthesized antithrombin III binding fragment of heparin (pentasaccharide) in rats.
    Thrombosis and haemostasis, 1990, Apr-12, Volume: 63, Issue:2

    Topics: Animals; Antithrombin III; Carbohydrate Sequence; Factor Xa Inhibitors; Fibrinolytic Agents; Hemorrh

1990