pentachlorophenol and Cancer of Liver
pentachlorophenol has been researched along with Cancer of Liver in 7 studies
PENTA: structure given in first source
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Pentachlorophenol (PCP) is a widely used biocidal compound with several industrial, agricultural and domestic applications." | 1.32 | CYP1a1, HSP70, P53, and c-fos expression in human liver carcinoma cells (HepG2) exposed to pentachlorophenol. ( Dorsey, WC; Tchounwou, PB, 2003) |
"Pentachlorophenol (PCP) is a widely used biocide that has been reported to be hepatocarcinogenic in mice." | 1.31 | Analysis of DNA adducts in rats exposed to pentachlorophenol. ( La, DK; Lin, PH; Swenberg, JA; Upton, PB, 2002) |
" Likewise, the chronic administration of a nontoxic level of pentachlorophenol in the diet of adult female CD-1 mice strongly inhibited hepatic tumor induction by long-term dietary administration of either safrole or 1'-hydroxysafrole." | 1.27 | Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver. ( Boberg, EW; Liem, A; Miller, EC; Miller, JA; Poland, A, 1983) |
Research
Studies (7)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (42.86) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 3 (42.86) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Dorsey, WC | 1 |
Tchounwou, PB | 1 |
Umemura, T | 1 |
Kai, S | 1 |
Hasegawa, R | 1 |
Kanki, K | 1 |
Kitamura, Y | 1 |
Nishikawa, A | 1 |
Hirose, M | 1 |
Boberg, EW | 1 |
Miller, EC | 1 |
Miller, JA | 1 |
Poland, A | 1 |
Liem, A | 1 |
Kedderis, GL | 1 |
Dyroff, MC | 1 |
Rickert, DE | 1 |
Dubois, M | 1 |
Plaisance, H | 1 |
Thomé, JP | 1 |
Kremers, P | 1 |
Lin, PH | 1 |
La, DK | 1 |
Upton, PB | 1 |
Swenberg, JA | 1 |
Meerman, JH | 1 |
Other Studies
7 other studies available for pentachlorophenol and Cancer of Liver
Article | Year |
---|---|
CYP1a1, HSP70, P53, and c-fos expression in human liver carcinoma cells (HepG2) exposed to pentachlorophenol.
Topics: Apoptosis; Carcinogenicity Tests; Cell Division; Cytochrome P-450 CYP1A1; Dose-Response Relationship | 2003 |
Prevention of dual promoting effects of pentachlorophenol, an environmental pollutant, on diethylnitrosamine-induced hepato- and cholangiocarcinogenesis in mice by green tea infusion.
Topics: Animals; Cholangiocarcinoma; Diethylnitrosamine; Environmental Pollutants; Liver Neoplasms; Pentachl | 2003 |
Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.
Topics: Animals; Carcinogens; Chlorophenols; Cytosol; Dioxoles; Female; Kinetics; Liver; Liver Neoplasms; Ma | 1983 |
Hepatic macromolecular covalent binding of the hepatocarcinogen 2,6-dinitrotoluene and its 2,4-isomer in vivo: modulation by the sulfotransferase inhibitors pentachlorophenol and 2,6-dichloro-4-nitrophenol.
Topics: Animals; Biotransformation; Carcinogens; Chlorophenols; Dinitrobenzenes; DNA; Liver; Liver Neoplasms | 1984 |
Hierarchical cluster analysis of environmental pollutants through P450 induction in cultured hepatic cells.
Topics: 7-Alkoxycoumarin O-Dealkylase; Analysis of Variance; Animals; Antibody Specificity; Benz(a)Anthracen | 1996 |
Analysis of DNA adducts in rats exposed to pentachlorophenol.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biological Assay; Carcinogens; Chromatography, High Pressure L | 2002 |
The initiation of gamma-glutamyltranspeptidase positive foci in the rat liver by N-hydroxy-2-acetylaminofluorene. The effect of the sulfation inhibitor pentachlorophenol.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Chlorophenols; Enzyme Induction; gamma-Glutamyltransfer | 1985 |