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pentachlorophenol and Cancer of Liver

pentachlorophenol has been researched along with Cancer of Liver in 7 studies

PENTA: structure given in first source

Research Excerpts

ExcerptRelevanceReference
"Pentachlorophenol (PCP) is a widely used biocidal compound with several industrial, agricultural and domestic applications."1.32CYP1a1, HSP70, P53, and c-fos expression in human liver carcinoma cells (HepG2) exposed to pentachlorophenol. ( Dorsey, WC; Tchounwou, PB, 2003)
"Pentachlorophenol (PCP) is a widely used biocide that has been reported to be hepatocarcinogenic in mice."1.31Analysis of DNA adducts in rats exposed to pentachlorophenol. ( La, DK; Lin, PH; Swenberg, JA; Upton, PB, 2002)
" Likewise, the chronic administration of a nontoxic level of pentachlorophenol in the diet of adult female CD-1 mice strongly inhibited hepatic tumor induction by long-term dietary administration of either safrole or 1'-hydroxysafrole."1.27Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver. ( Boberg, EW; Liem, A; Miller, EC; Miller, JA; Poland, A, 1983)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dorsey, WC1
Tchounwou, PB1
Umemura, T1
Kai, S1
Hasegawa, R1
Kanki, K1
Kitamura, Y1
Nishikawa, A1
Hirose, M1
Boberg, EW1
Miller, EC1
Miller, JA1
Poland, A1
Liem, A1
Kedderis, GL1
Dyroff, MC1
Rickert, DE1
Dubois, M1
Plaisance, H1
Thomé, JP1
Kremers, P1
Lin, PH1
La, DK1
Upton, PB1
Swenberg, JA1
Meerman, JH1

Other Studies

7 other studies available for pentachlorophenol and Cancer of Liver

ArticleYear
CYP1a1, HSP70, P53, and c-fos expression in human liver carcinoma cells (HepG2) exposed to pentachlorophenol.
    Biomedical sciences instrumentation, 2003, Volume: 39

    Topics: Apoptosis; Carcinogenicity Tests; Cell Division; Cytochrome P-450 CYP1A1; Dose-Response Relationship

2003
Prevention of dual promoting effects of pentachlorophenol, an environmental pollutant, on diethylnitrosamine-induced hepato- and cholangiocarcinogenesis in mice by green tea infusion.
    Carcinogenesis, 2003, Volume: 24, Issue:6

    Topics: Animals; Cholangiocarcinoma; Diethylnitrosamine; Environmental Pollutants; Liver Neoplasms; Pentachl

2003
Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.
    Cancer research, 1983, Volume: 43, Issue:11

    Topics: Animals; Carcinogens; Chlorophenols; Cytosol; Dioxoles; Female; Kinetics; Liver; Liver Neoplasms; Ma

1983
Hepatic macromolecular covalent binding of the hepatocarcinogen 2,6-dinitrotoluene and its 2,4-isomer in vivo: modulation by the sulfotransferase inhibitors pentachlorophenol and 2,6-dichloro-4-nitrophenol.
    Carcinogenesis, 1984, Volume: 5, Issue:9

    Topics: Animals; Biotransformation; Carcinogens; Chlorophenols; Dinitrobenzenes; DNA; Liver; Liver Neoplasms

1984
Hierarchical cluster analysis of environmental pollutants through P450 induction in cultured hepatic cells.
    Ecotoxicology and environmental safety, 1996, Volume: 34, Issue:3

    Topics: 7-Alkoxycoumarin O-Dealkylase; Analysis of Variance; Animals; Antibody Specificity; Benz(a)Anthracen

1996
Analysis of DNA adducts in rats exposed to pentachlorophenol.
    Carcinogenesis, 2002, Volume: 23, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biological Assay; Carcinogens; Chromatography, High Pressure L

2002
The initiation of gamma-glutamyltranspeptidase positive foci in the rat liver by N-hydroxy-2-acetylaminofluorene. The effect of the sulfation inhibitor pentachlorophenol.
    Carcinogenesis, 1985, Volume: 6, Issue:6

    Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Chlorophenols; Enzyme Induction; gamma-Glutamyltransfer

1985
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