penicillin-g-sodium has been researched along with Escherichia-coli-Infections* in 1 studies
1 other study(ies) available for penicillin-g-sodium and Escherichia-coli-Infections
| Article | Year |
|---|---|
Synthesis and evaluation of adenosine containing 3-arylfuran-2(5H)-ones as tyrosyl-tRNA synthetase inhibitors.
Tyrosyl-tRNA synthetase (TyrRS) is an aminoacyl-tRNA synthetase family protein that possesses an essential role in bacterial protein synthesis. The synthesis, structure-activity relationship, and evolution of a novel series of adenosine-containing 3-arylfuran-2(5H)-ones as TyrRS inhibitors are described. Advanced compound d3 from this series exhibited excellent affinity for TyrRS with IC Topics: Adenosine; Anti-Bacterial Agents; Enzyme Inhibitors; Escherichia coli; Escherichia coli Infections; HeLa Cells; Humans; Molecular Docking Simulation; Pseudomonas aeruginosa; Pseudomonas Infections; Structure-Activity Relationship; Tyrosine-tRNA Ligase | 2017 |