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penicillin g and Scleroderma, Systemic

penicillin g has been researched along with Scleroderma, Systemic in 6 studies

Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.

Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

Research Excerpts

ExcerptRelevanceReference
"Penicillin G (PenG) has successfully been used for therapy of dermal fibrosis in patients suffering from systemic sclerosis (SSc)."1.31Penicillin G does not alter collagen type I metabolism of dermal fibroblasts in culture. ( Anderegg, U; Haustein, UF; Wilczek, A, 2000)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wessbecher, R1
Stangl, S1
Blumenkrantz, N1
Asboe-Hansen, G3
Anderegg, U1
Wilczek, A1
Haustein, UF1
Ohlenschlaeger, K1
Tissot, J1

Other Studies

6 other studies available for penicillin g and Scleroderma, Systemic

ArticleYear
Management of tolerance induction in patients with suspected penicillin allergy--a case study.
    International journal of dermatology, 2009, Volume: 48, Issue:5

    Topics: Administration, Oral; Anti-Bacterial Agents; Desensitization, Immunologic; Dose-Response Relationshi

2009
Variation of urinary acid glycosaminoglycan and collagen metabolite excretion with disease activity in generalized scleroderma.
    Acta dermato-venereologica, 1980, Volume: 60, Issue:1

    Topics: Adult; Aged; Collagen; Female; Follow-Up Studies; Glutamine; Glycosaminoglycans; Humans; Hydralazine

1980
Treatment of generalized scleroderma with inhibitors of collagen synthesis.
    International journal of dermatology, 1982, Volume: 21, Issue:3

    Topics: Catechin; Chlorpromazine; Collagen; Dextrothyroxine; Glutamine; Humans; Hydralazine; Levodopa; Penic

1982
Penicillin G does not alter collagen type I metabolism of dermal fibroblasts in culture.
    Dermatology (Basel, Switzerland), 2000, Volume: 200, Issue:2

    Topics: Cell Division; Cells, Cultured; Collagen; Dermis; Female; Fibroblasts; Humans; Middle Aged; Penicill

2000
Treatment of generalized scleroderma: updated results.
    Acta dermato-venereologica, 1979, Volume: 59, Issue:5

    Topics: Chlorpromazine; Collagen; Drug Evaluation; Glutamine; Glycosaminoglycans; Humans; Hydralazine; Levod

1979
Scleroderma treated with the diethylaminoethylester Hydriodide salt of Penicillin G.
    Dermatologica, 1967, Volume: 134, Issue:3

    Topics: Adolescent; Adult; Aged; Alpha-Globulins; Beta-Globulins; Child; Female; Humans; Male; Middle Aged;

1967