penicillin g has been researched along with Rheumatic Heart Disease in 35 studies
Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.
Rheumatic Heart Disease: Cardiac manifestation of systemic rheumatological conditions, such as RHEUMATIC FEVER. Rheumatic heart disease can involve any part the heart, most often the HEART VALVES and the ENDOCARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The current prophylactic treatment to prevent rheumatic heart disease requires four-weekly intramuscular injection of a suspension of the poorly soluble benzathine salt form of penicillin G (BPG) often for more than 10 years." | 3.88 | Lessons learned in the development of sustained release penicillin drug delivery systems for the prophylactic treatment of rheumatic heart disease (RHD). ( Boyd, BJ; Bulitta, JB; Carapetis, JR; Landersdorfer, C; Montagnat, OD; Sheel, M; Webster, GR; Wyber, R, 2018) |
| "Age, weight, cardiac status, and streptococcal infections among the patients and their family members studied in each program were comparable." | 2.66 | Rheumatic fever recurrences: controlled study of 3-week versus 4-week benzathine penicillin prevention programs. ( Chiou, JF; Hsieh, KH; Hsieh, RP; Lin, GJ; Lue, HC; Wu, MH, 1986) |
| "The incidence of acute rheumatic fever has seen a dramatic decline over the last 15 to 20 years in most developed countries and treatment of this disease has changed little since." | 1.32 | Recurrent acute rheumatic fever: a forgotten diagnosis? ( Barker, TA; Clarke, B; Denley, H; Grötte, GJ; Kadir, IS, 2004) |
| "Mitral insufficiency was the major functional defect in these children whose mean age was 8." | 1.27 | Rheumatic heart disease in Nigerian children: clinical and preventive aspects. ( Coker, AO; Fadahunsi, HO; Usoro, PD, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (85.71) | 18.7374 |
| 1990's | 2 (5.71) | 18.2507 |
| 2000's | 1 (2.86) | 29.6817 |
| 2010's | 2 (5.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Page-Sharp, M | 1 |
| Coward, J | 1 |
| Moore, BR | 1 |
| Salman, S | 1 |
| Marshall, L | 1 |
| Davis, TME | 1 |
| Batty, KT | 1 |
| Manning, L | 1 |
| Montagnat, OD | 1 |
| Webster, GR | 1 |
| Bulitta, JB | 1 |
| Landersdorfer, C | 1 |
| Wyber, R | 1 |
| Sheel, M | 1 |
| Carapetis, JR | 1 |
| Boyd, BJ | 1 |
| LORENZ, E | 1 |
| WENDLER, H | 1 |
| SHOKH, BP | 1 |
| SONDAG, RF | 1 |
| LANGSTON, WT | 1 |
| GUASCH, J | 1 |
| WESSEL, G | 1 |
| BOLOTINA, AIu | 1 |
| Kadir, IS | 1 |
| Barker, TA | 1 |
| Clarke, B | 1 |
| Denley, H | 1 |
| Grötte, GJ | 1 |
| Martínez-Díaz, J | 1 |
| Christenson, B | 1 |
| Rodríguez, JR | 1 |
| Sánchez, C | 1 |
| Ramírez-Ronda, CH | 1 |
| Edginton, ME | 1 |
| Gear, JS | 1 |
| Khomin, LV | 1 |
| Il'nitskiĭ, VP | 1 |
| Burnell, RH | 1 |
| Richardson, ME | 1 |
| Wyse, DG | 1 |
| McAnulty, JH | 1 |
| Rahimtoola, SH | 1 |
| Shiokawa, Y | 1 |
| Majeed, HA | 2 |
| Khuffash, FA | 2 |
| Bhatnagar, S | 1 |
| Farwana, S | 2 |
| Yusuf, AR | 2 |
| Yousof, AM | 2 |
| Fadahunsi, HO | 1 |
| Coker, AO | 1 |
| Usoro, PD | 1 |
| Walker, K | 1 |
| Sprenger, K | 1 |
| de Moor, M | 1 |
| Padmavati, S | 1 |
| Gupta, V | 1 |
| Prakash, K | 1 |
| Sharma, KB | 1 |
| Lue, HC | 1 |
| Wu, MH | 1 |
| Hsieh, KH | 1 |
| Lin, GJ | 1 |
| Hsieh, RP | 1 |
| Chiou, JF | 1 |
| Khan, N | 1 |
| Bosmanský, K | 1 |
| Urbánek, T | 1 |
| Zatkalík, M | 1 |
| Srámek, J | 1 |
| Angelino, PF | 1 |
| Amati, L | 1 |
| Sturlese, U | 1 |
| Tortore, P | 1 |
| Taranta, A | 2 |
| Gordis, L | 1 |
| Hellmuth, GA | 1 |
| Spencer, WH | 1 |
| Thornsberry, C | 1 |
| Moody, MD | 1 |
| Wenger, NK | 1 |
| Klein, W | 1 |
| Klein, G | 1 |
| Caldwell, RL | 1 |
| Hurwitz, RA | 1 |
| Girod, DA | 1 |
| Doyle, EF | 1 |
| Spagnuolo, M | 2 |
| Kuttner, AG | 1 |
| Markowitz, M | 1 |
| Thomas, LA | 1 |
| Milman, DH | 1 |
| Rodriquez-Torres, R | 1 |
| Kuznetsov, AI | 1 |
| Spitsin, KV | 1 |
| Dolgopolova, AV | 1 |
| Benevolenskaia, LI | 1 |
| Spada, A | 1 |
| Gennaro, T | 1 |
| Ambrosiani, S | 1 |
| Feinstein, AR | 1 |
| Levitt, M | 1 |
| Jonas, S | 1 |
| Tursky, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Streptococcus Salivarius BLIS (Bacteriocin-like Inhibitory Substance) K12 as Preventive Measure for Rheumatic Children.[NCT02407106] | 30 participants (Anticipated) | Interventional | 2015-09-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for penicillin g and Rheumatic Heart Disease
| Article | Year |
|---|---|
Lyme disease: a review.
Topics: Antibodies; Antigen-Antibody Complex; Diagnosis, Differential; Humans; Lyme Disease; Penicillin G; R | 1984 |
The prevention of rheumatic fever: opportunities, frustrations, and challenges.
Topics: Administration, Oral; Adolescent; Child; Humans; Penicillin G; Penicillin G Benzathine; Rheumatic Fe | 1972 |
2 trials available for penicillin g and Rheumatic Heart Disease
| Article | Year |
|---|---|
Rheumatic fever recurrences: controlled study of 3-week versus 4-week benzathine penicillin prevention programs.
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Drug Administration Schedule; Female; | 1986 |
Discontinuation of antistreptococcal prophylaxis. A double-blind study in rheumatic patients free of heart disease.
Topics: Adolescent; Adult; Aged; Evaluation Studies as Topic; Follow-Up Studies; Humans; Middle Aged; Penici | 1966 |
31 other studies available for penicillin g and Rheumatic Heart Disease
| Article | Year |
|---|---|
Penicillin Dried Blood Spot Assay for Use in Patients Receiving Intramuscular Benzathine Penicillin G and Other Penicillin Preparations To Prevent Rheumatic Fever.
Topics: Adult; Aged; Anti-Bacterial Agents; Dried Blood Spot Testing; Female; Humans; Injections, Intramuscu | 2017 |
Lessons learned in the development of sustained release penicillin drug delivery systems for the prophylactic treatment of rheumatic heart disease (RHD).
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Delayed-Action Preparations; Drug Liberation; Drug St | 2018 |
[PRACTICAL EXPERIENCES IN THE PREVENTION OF RECURRENCES OF RHEUMATIC FEVER IN CHILDHOOD].
Topics: Child; Ethylenediamines; Humans; Penicillin G; Penicillin G Benzathine; Penicillin G Procaine; Penic | 1963 |
[SOME PROBLEMS OF PREVENTION OF RELAPSES OF RHEUMATISM IN CHILDREN].
Topics: Adolescent; Child; Ethylenediamines; Humans; Infant; Penicillin G; Penicillin G Benzathine; Recurren | 1963 |
RHEUMATIC FEVER PROPHYLAXIS IN DOWNSTATE ILLINOIS.
Topics: Drug Therapy; Ethylenediamines; Humans; Illinois; Penicillin G; Penicillin G Benzathine; Penicillins | 1964 |
[PREVENTION OF RHEUMATIC DISEASE. PRELIMINARY COMMUNICATION].
Topics: Adolescent; Child; Drug Therapy; Ethylenediamines; Humans; Infant; Infant, Newborn; Penicillin G; Pe | 1964 |
[SUGGESTIONS ON THE ORGANIZATION OF THE PREVENTION OF RECURRENT CARDITIS WITH BENZATHINE PENICILLIN].
Topics: Child; Drug Therapy; Ethylenediamines; Germany; Germany, East; Humans; Myocarditis; Penicillin G; Pe | 1965 |
[APROPOS OF INDICATIONS FOR THE PREVENTIVE BICILLIN THERAPY IN RECURRENT RHEUMATISM].
Topics: Cardiac Surgical Procedures; Drug Therapy; Ethylenediamines; Humans; Mitral Valve Stenosis; Penicill | 1965 |
Recurrent acute rheumatic fever: a forgotten diagnosis?
Topics: Acute Disease; Adult; Amoxicillin; Anti-Inflammatory Agents; Aortic Valve; Aortic Valve Insufficienc | 2004 |
Rheumatic fever article questioned.
Topics: Child; Humans; Penicillin G; Penicillin G Benzathine; Recurrence; Rheumatic Fever; Rheumatic Heart D | 1984 |
Rheumatic heart disease in Soweto -- a programme for secondary prevention.
Topics: Adolescent; Adult; Child; Child, Preschool; Community Health Services; Hospitalization; Humans; Peni | 1982 |
[Effect of seasonal antirheumatic measures on the course of rheumatic heart disease].
Topics: Drug Combinations; Humans; Mitral Valve Insufficiency; Penicillin G; Penicillin G Benzathine; Penici | 1980 |
Fever, cardiac failure and arteritis in a child with rheumatic carditis.
Topics: Angiography; Arteritis; Cardiac Output, Low; Child; Corynebacterium diphtheriae; Corynebacterium Inf | 1997 |
Antibiotic prophylaxis in patients with rheumatic heart disease and prosthetic devices.
Topics: Anti-Bacterial Agents; Endocarditis, Bacterial; Heart Valve Prosthesis; Humans; Penicillin G; Recurr | 1978 |
Proceedings: Study on the chemoprophylaxis of rheumatic heart disease.
Topics: Humans; Palatine Tonsil; Penicillin G; Penicillin V; Pharynx; Rheumatic Heart Disease; Streptococcus | 1975 |
Acute rheumatic polyarthritis. The duration of secondary prophylaxis.
Topics: Acute Disease; Arthritis, Juvenile; Child; Child, Preschool; Drug Administration Schedule; Endocardi | 1990 |
Rheumatic heart disease in Nigerian children: clinical and preventive aspects.
Topics: Child; Child, Preschool; Female; Humans; Male; Mitral Valve Insufficiency; Nigeria; Penicillin G; Pe | 1987 |
Long-term penicillin in Sydenham's chorea.
Topics: Chorea; Humans; Penicillin G; Penicillin G Benzathine; Rheumatic Fever; Rheumatic Heart Disease | 1989 |
Penicillin for rheumatic fever prophylaxis 3-weekly or 4-weekly schedule?
Topics: Child; Drug Administration Schedule; Humans; India; Penicillin G; Penicillin G Benzathine; Pilot Pro | 1987 |
The natural history of acute rheumatic fever in Kuwait: a prospective six year follow-up report.
Topics: Acute Disease; Child; Child, Preschool; Chorea; Epidemiologic Methods; Female; Follow-Up Studies; Hu | 1986 |
[Preventive care in real rheumatic patients with emphasis on subsequent heart damage].
Topics: Adolescent; Child; Female; Heart Valve Diseases; Humans; Male; Middle Aged; Penicillin G; Penicillin | 1986 |
[Incidence of valvular cardiopathies secondary to rheumatic infection in relation to the therapy adopted. Follow-up study of 148 patients for 2 to 8 years].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Delayed-Action Preparations; Electrocardiography; Fe | 1972 |
Preventing rheumatic fever and rheumatic heart disease.
Topics: Humans; Penicillin G; Penicillin G Benzathine; Pharyngitis; Pharynx; Rheumatic Fever; Rheumatic Hear | 1973 |
Rheumatic fever chemoprophylaxis and penicillin-resistant gingival organisms.
Topics: Administration, Oral; Bacteriological Techniques; Endocarditis, Bacterial; Erythromycin; Gingiva; Hu | 1970 |
[Therapy and prevention of myocarditis following open-heart surgery for mitral valve insufficiency].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Cephaloridine; Child, Preschool; | 1970 |
Subacute bacterial endocarditis in children. Current status.
Topics: Adult; Age Factors; Aortic Valve Insufficiency; Child; Child, Preschool; Endocarditis, Subacute Bact | 1971 |
The risk of bacterial endocarditis during antirheumatic prophylaxis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Endocarditis, Bacterial; Female; Humans; Joint Dise | 1967 |
Anxiety in children with rheumatic fever. Relation to route of prophylaxis.
Topics: Administration, Oral; Adolescent; Anxiety; Attitude; Child; Female; Humans; Injections, Intramuscula | 1970 |
[The cardiovascular system in children with rheumatism and subjected to seasonal bicillin prophylaxis].
Topics: Child; Humans; Penicillin G; Prednisolone; Rheumatic Fever; Rheumatic Heart Disease | 1967 |
[Apropos of the article by V. I. Zuzanova and co-workers "Effectiveness of Secondary Prevention of Rheumatism in Children" published in the journal "Pediatrics", No. 4, 1966].
Topics: Child; Humans; Penicillin G; Rheumatic Fever; Rheumatic Heart Disease | 1967 |
[5 years of antirheumatic therapy at the Divisione Pediatrica dell'Ospedale Civile of Cuneo. Clinical, therapeutic and preventive aspects].
Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Female; Humans; Italy; Male; Penicillin G; Penicil | 1968 |