Page last updated: 2024-11-07

penicillin g and Pneumonia, Bacterial

penicillin g has been researched along with Pneumonia, Bacterial in 31 studies

Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.

Pneumonia, Bacterial: Inflammation of the lung parenchyma that is caused by bacterial infections.

Research Excerpts

ExcerptRelevanceReference
"Sepsis is a common cause of morbidity and mortality."5.29Granulocyte colony-stimulating factor versus placebo in addition to penicillin G in a randomized blinded study of gram-negative pneumonia sepsis: analysis of survival and multisystem organ failure. ( Millard, FE; Samuelson, D; Sharpe, RW; Smith, WS; Sumnicht, GE, 1995)
"We present the first case of mediastinitis and the third case of pneumonia attributed to Actinomyces odontolyticus."2.39Actinomyces odontolyticus thoracopulmonary infections. Two cases in lung and heart-lung transplant recipients and a review of the literature. ( Bassiri, AG; Girgis, RE; Theodore, J, 1996)
"Penicillin G successfully treated 82% (126/154) of the study group and improvement was marked on the first day of treatment."1.37Outcome of children hospitalized with community-acquired pneumonia treated with aqueous penicillin G. ( Araújo, M; Nascimento-Carvalho, CM; Simbalista, R, 2011)
"Inhalation anthrax is a rare and almost uniformly fatal form of human anthrax caused by the inhalation of spores of Bacillus anthracis."1.30Anthrax pneumonia. ( Klotz, SA; Penn, CC, 1997)
"Infection of a chylothorax is thought not to occur because chyle is inherently bacteriostatic."1.30Infected spontaneous chylothorax. ( Hadeli, O; Natrajan, S; Quan, SF, 1998)
"Sepsis is a common cause of morbidity and mortality."1.29Granulocyte colony-stimulating factor versus placebo in addition to penicillin G in a randomized blinded study of gram-negative pneumonia sepsis: analysis of survival and multisystem organ failure. ( Millard, FE; Samuelson, D; Sharpe, RW; Smith, WS; Sumnicht, GE, 1995)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.23)18.7374
1990's12 (38.71)18.2507
2000's9 (29.03)29.6817
2010's8 (25.81)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Gou, S1
Li, B1
Ouyang, X1
Ba, Z1
Zhong, C1
Zhang, T1
Chang, L1
Zhu, Y1
Zhang, J1
Zhu, N1
Zhang, Y1
Liu, H1
Ni, J1
Brandão, A1
Simbalista, R2
Borges, IC1
Andrade, DC1
Araújo, M2
Nascimento-Carvalho, CM2
Qazi, SA1
Fox, MP1
Thea, DM1
Agweyu, A2
Gathara, D1
Oliwa, J1
Muinga, N1
Edwards, T1
Allen, E1
Maleche-Obimbo, E1
English, M2
Lorgelly, PK1
Atkinson, M2
Lakhanpaul, M2
Smyth, AR1
Vyas, H2
Weston, V2
Stephenson, T2
Opiyo, N1
Korppi, M1
Schwab, J1
Lantos, J1
Tanz, RR1
Meadow, W1
FLIPPIN, HF1
BARTHOLOMEW, LE1
MATTEUCCI, WV1
SCHIMMEL, NH1
Cetinkaya, F1
Gogremis, A1
Kutluk, G1
David, G1
Perpoint, T1
Boibieux, A1
Pialat, JB1
Salord, H1
Devouassoux, M1
Chidiac, C1
Peyramond, D1
Soler V, T1
Salamanca F, L1
Molina, E1
Mankhambo, LA1
Chiwaya, KW1
Phiri, A1
Graham, SM1
Smyth, A1
Sithole, J1
Owen, V1
Halliday, K1
Sammons, H1
Crane, J1
Guntupalli, N1
Walton, L1
Ninan, T1
Morjaria, A1
Smith, WS1
Sumnicht, GE1
Sharpe, RW1
Samuelson, D1
Millard, FE1
Bohte, R1
van't Wout, JW1
Lobatto, S1
Blussé van Oud Alblas, A1
Boekhout, M1
Nauta, EH1
Hermans, J1
van den Broek, PJ1
Gaillat, J1
Bru, JP1
Sedallian, A1
Hamour, A1
Bonnington, A1
Wilkins, EG1
Regamey, C1
Cuadrado-Gómez, LM1
Arranz-Caso, JA1
Cuadros-González, J1
Albarrán-Hernández, F1
Bassiri, AG1
Girgis, RE1
Theodore, J1
Penn, CC1
Klotz, SA1
Natrajan, S1
Hadeli, O1
Quan, SF1
Léophonte, P1
Sherer, Y1
Bakshi, E1
Rotman, P1
Levy, Y1
Shoenfeld, Y1
Tsai, WC1
Rosón, B1
Carratalà, J1
Tubau, F1
Dorca, J1
Liñares, J1
Pallares, R1
Manresa, F1
Gudiol, F1
Allewelt, M1
Lode, H1
Miyake, S1
Sawabe, E1
Inase, N1
Yoshizawa, Y1
Nijs, A1
Vandekerkhof, J1
Cartuyvels, R1
Magerman, K1
Mewis, A1
Peeters, V1
Rummens, JL1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Amoxicillin Versus Benzyl Penicillin for Severe Childhood Pneumonia Amongst Inpatients: An Open Label Randomised Controlled Non-inferiority Trial[NCT01399723]Phase 3561 participants (Actual)Interventional2011-09-30Completed
Ceftriaxone Versus Chloramphenicol for Treatment of Severe Pneumonia in Children Aged Less Than Five Years at Mulago Hospital: A Randomized Controlled Trial[NCT00372541]Phase 3348 participants (Anticipated)Interventional2006-09-30Completed
Assessing the Feasibility and Effectiveness of Introducing Pulse Oximetry in IMCI Services to Manage Acute Respiratory Infections at First Level Health Facilities of Bangladesh[NCT03750747]612 participants (Anticipated)Interventional2018-12-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Outcome (Death/Readmission) at 14 Days as Determined by Telephone or Direct Interview

Definition of death as described in third secondary outcome measure. (NCT01399723)
Timeframe: Day 14

Interventionparticipants (Number)
Amoxicillin33
Penicillin42

Treatment Failure at 48 Hours (Two Full Days After Enrollment)

Development of any signs of very severe pneumonia at any time Hypoxemia defined as SpO2 <85% or <80% for altitude < or ≥1500m respectively measured after minimum of 3 minutes on ambient air Persistent vomiting (occurring within 30 minutes of administration of amoxicillin with failure to retain drug after 3 successive attempts at administration) at any time Clinical diagnosis of new bacterial co-morbid condition requiring revision of antibiotic treatment at any time Lower chest wall indrawing Temperature ≥38◦C Respiratory rate ≥5bpm of admission rate if above age-adjusted normal upper limit (NCT01399723)
Timeframe: 48 hours

Interventionparticipants (Number)
Amoxicillin20
Penicillin21

Treatment Failure at or Before Discharge / Day 5 Post Enrollment (Whichever Occurs First)

Treatment failure as defined in the primary outcome measure. (NCT01399723)
Timeframe: Patients will be followed up from the day of hospitalisation (day 0) until the day of medical discharge (average duration of 3 days) or until day 5 of hospitalisation (whichever occurs first).

Interventionparticipants (Number)
Amoxicillin30
Penicillin29

Reviews

6 reviews available for penicillin g and Pneumonia, Bacterial

ArticleYear
Experience developing national evidence-based clinical guidelines for childhood pneumonia in a low-income setting--making the GRADE?
    BMC pediatrics, 2012, Jan-01, Volume: 12

    Topics: Amoxicillin; Ceftriaxone; Child; Developing Countries; Evidence-Based Medicine; Gentamicins; Humans;

2012
Secondary pulmonary syphilis: report of a likely case and literature review.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Feb-01, Volume: 42, Issue:3

    Topics: Adult; Anti-Bacterial Agents; HIV Infections; Humans; Male; Penicillin G; Pneumonia, Bacterial; Syph

2006
[Various new pathogens in pneumonia].
    Schweizerische medizinische Wochenschrift, 1995, Nov-11, Volume: 125, Issue:45

    Topics: Chlamydophila pneumoniae; Humans; Orthohantavirus; Penicillin G; Penicillin Resistance; Pneumonia, B

1995
Actinomyces odontolyticus thoracopulmonary infections. Two cases in lung and heart-lung transplant recipients and a review of the literature.
    Chest, 1996, Volume: 109, Issue:4

    Topics: Actinomycosis; Administration, Oral; Adult; Debridement; Heart-Lung Transplantation; Humans; Injecti

1996
[Bacterial pneumonia].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 1

    Topics: Ampicillin; Drug Resistance; Haemophilus Infections; Haemophilus influenzae; Humans; Japan; Penicill

2002
Streptococcus pneumoniae-infected aneurysm extending from a persistent lobar pneumonia: case report and review of the literature.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2002, Volume: 21, Issue:5

    Topics: Aged; Aneurysm, Infected; Aorta, Abdominal; Humans; Male; Penicillin G; Penicillins; Pneumococcal In

2002

Trials

7 trials available for penicillin g and Pneumonia, Bacterial

ArticleYear
Oral amoxicillin versus benzyl penicillin for severe pneumonia among kenyan children: a pragmatic randomized controlled noninferiority trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Apr-15, Volume: 60, Issue:8

    Topics: Amoxicillin; Anti-Bacterial Agents; Child, Preschool; Female; Humans; Infant; Kenya; Male; Penicilli

2015
Oral versus i.v. antibiotics for community-acquired pneumonia in children: a cost-minimisation analysis.
    The European respiratory journal, 2010, Volume: 35, Issue:4

    Topics: Administration, Oral; Adolescent; Amoxicillin; Anti-Bacterial Agents; Child; Child, Hospitalized; Ch

2010
Comparison of two antibiotic regimens in the empirical treatment of severe childhood pneumonia.
    Indian journal of pediatrics, 2004, Volume: 71, Issue:11

    Topics: Ceftriaxone; Child, Hospitalized; Child, Preschool; Chloramphenicol; Community-Acquired Infections;

2004
Comparison of oral amoxicillin and intravenous benzyl penicillin for community acquired pneumonia in children (PIVOT trial): a multicentre pragmatic randomised controlled equivalence trial.
    Thorax, 2007, Volume: 62, Issue:12

    Topics: Administration, Oral; Amoxicillin; Anti-Bacterial Agents; Child, Preschool; Community-Acquired Infec

2007
Efficacy and safety of azithromycin versus benzylpenicillin or erythromycin in community-acquired pneumonia.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1995, Volume: 14, Issue:3

    Topics: Administration, Oral; Adult; Aged; Azithromycin; Community-Acquired Infections; Erythromycin; Female

1995
Penicillin G/ofloxacin versus erythromycin/amoxicillin-clavulanate in the treatment of severe community-acquired pneumonia.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1994, Volume: 13, Issue:8

    Topics: Adult; Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulanic Acids; Community

1994
Usefulness of betalactam therapy for community-acquired pneumonia in the era of drug-resistant Streptococcus pneumoniae: a randomized study of amoxicillin-clavulanate and ceftriaxone.
    Microbial drug resistance (Larchmont, N.Y.), 2001,Spring, Volume: 7, Issue:1

    Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactam Resistance;

2001

Other Studies

18 other studies available for penicillin g and Pneumonia, Bacterial

ArticleYear
Novel Broad-Spectrum Antimicrobial Peptide Derived from Anoplin and Its Activity on Bacterial Pneumonia in Mice.
    Journal of medicinal chemistry, 2021, 08-12, Volume: 64, Issue:15

    Topics: Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Antineoplastic Agents; Cell Line; C

2021
Retrospective analysis of the efficacies of two different regimens of aqueous penicillin G administered to children with pneumonia.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:3

    Topics: Anti-Bacterial Agents; Child; Child, Preschool; Community-Acquired Infections; Drug Administration S

2014
Editorial commentary: ambulatory management of chest-indrawing pneumonia.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Apr-15, Volume: 60, Issue:8

    Topics: Amoxicillin; Anti-Bacterial Agents; Female; Humans; Male; Penicillin G; Pneumonia, Bacterial

2015
Outcome of children hospitalized with community-acquired pneumonia treated with aqueous penicillin G.
    Clinics (Sao Paulo, Brazil), 2011, Volume: 66, Issue:1

    Topics: Anti-Bacterial Agents; Brazil; Child; Child, Preschool; Cohort Studies; Community-Acquired Infection

2011
Diagnosis and treatment of community-acquired pneumonia in children.
    Acta paediatrica (Oslo, Norway : 1992), 2012, Volume: 101, Issue:7

    Topics: Amoxicillin; Anti-Bacterial Agents; Child; Community-Acquired Infections; Finland; Humans; Lung; Pen

2012
Editors' comments.
    Acta paediatrica (Oslo, Norway : 1992), 2012, Volume: 101, Issue:7

    Topics: Amoxicillin; Anti-Bacterial Agents; Humans; Penicillin G; Penicillin V; Pneumonia, Bacterial; Pneumo

2012
The hydriodide of diethylaminoethyl ester of penicillin G, neo-penil. V. A comparative study of the treatment of bacterial pneumonias with procaine penicillin.
    Diseases of the chest, 1953, Volume: 23, Issue:2

    Topics: Esters; Penicillin G; Penicillin G Procaine; Penicillins; Pneumonia; Pneumonia, Bacterial

1953
[In vitro antimicrobial susceptibility of anaerobic bacteria isolated from pleuropulmonary infections].
    Revista medica de Chile, 2006, Volume: 134, Issue:4

    Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Bacteroidaceae Infections; Chloram

2006
Lobar pneumonia caused by nontyphoidal Salmonella in a Malawian child.
    The Pediatric infectious disease journal, 2006, Volume: 25, Issue:12

    Topics: Anti-Bacterial Agents; Ceftriaxone; Female; Gentamicins; HIV Infections; Hospitalization; Humans; In

2006
Granulocyte colony-stimulating factor versus placebo in addition to penicillin G in a randomized blinded study of gram-negative pneumonia sepsis: analysis of survival and multisystem organ failure.
    Blood, 1995, Aug-15, Volume: 86, Issue:4

    Topics: Animals; Double-Blind Method; Female; Granulocyte Colony-Stimulating Factor; Hemoglobins; Leukocyte

1995
Severe community acquired pneumonia associated with a desquamating rash due to group A beta-haemolytic streptococcus.
    The Journal of infection, 1994, Volume: 29, Issue:1

    Topics: Community-Acquired Infections; Humans; Male; Middle Aged; Penicillin G; Pleural Effusion; Pneumonia,

1994
Pasteurella pneumotropica pneumonia in a patient with AIDS.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Bronchoalveolar Lavage Fluid; Humans; Male; Pasteurella;

1995
Anthrax pneumonia.
    Seminars in respiratory infections, 1997, Volume: 12, Issue:1

    Topics: Animals; Animals, Domestic; Anthrax; Diagnosis, Differential; Humans; Occupational Exposure; Penicil

1997
Infected spontaneous chylothorax.
    Diagnostic microbiology and infectious disease, 1998, Volume: 30, Issue:1

    Topics: Adult; Chylothorax; Humans; Immunocompromised Host; Kidney Transplantation; Male; Penicillin G; Peni

1998
[Management of community-acquired pneumopathies of adults in the city and at the hospital].
    Presse medicale (Paris, France : 1983), 1998, Volume: 27 Suppl 4

    Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cephalospo

1998
Comparative clinical study of cefonicid, chloramphenicol, and penicillin in community-acquired pneumonia.
    International journal of molecular medicine, 1998, Volume: 2, Issue:3

    Topics: Anti-Bacterial Agents; Blood Cell Count; Cefonicid; Chloramphenicol; Community-Acquired Infections;

1998
Meningococcal pneumonia: a case report.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 1998, Volume: 31, Issue:4

    Topics: Adult; Humans; Male; Meningococcal Infections; Penicillin G; Pneumonia, Bacterial

1998
[Diagnosis and therapy of abscess forming pneumonia].
    Therapeutische Umschau. Revue therapeutique, 2001, Volume: 58, Issue:10

    Topics: Diagnosis, Differential; Drug Therapy, Combination; Humans; Lung Abscess; Microbial Sensitivity Test

2001