Page last updated: 2024-11-07

penicillin g and Osteoradionecrosis

penicillin g has been researched along with Osteoradionecrosis in 2 studies

Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.

Osteoradionecrosis: Necrosis of bone following radiation injury.

Research Excerpts

ExcerptRelevanceReference
"Conventional treatment of osteoradionecrosis of mandible is by antibiotics combined if necessary with a hemimandibulectomy."1.27[Current treatment of osteoradionecrosis]. ( Blanc, JL; Cheynet, F; Lachard, A; Lachard, J; Lagier, JP; Rakotobe, P, 1986)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lagier, JP1
Blanc, JL1
Lachard, A1
Cheynet, F1
Rakotobe, P1
Lachard, J1
Marx, RE1
Johnson, RP1
Kline, SN1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Normal Tissue Oxygenation Following Radiotherapy[NCT00677040]20 participants (Actual)Observational2008-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Tissue Oxygenation

Transcutaneous oxygen detector is used to measure the partial pressure of oxygen. The unit detects electrolytes ionized by oxygen. The measuring electrode also heats the skin being measured to facilitate maximal bloodflow to the area. (NCT00677040)
Timeframe: One visit for 20 minutes

InterventionmmHg (Mean)
Subjects62.5

Skin and Soft Tissue Toxicity Will be Assessed Using the RTOG/EORTC Late Radiation Morbidity Scoring Schema When Oxygenation is Measured.

(NCT00677040)
Timeframe: One visit

InterventionParticipants (Count of Participants)
late subcutaneous toxicitiy score 1late subcutaneous toxcity score 2late skin toxicity score 1late skin toxicity score 2
Subjects191191

Trials

1 trial available for penicillin g and Osteoradionecrosis

ArticleYear
Prevention of osteoradionecrosis: a randomized prospective clinical trial of hyperbaric oxygen versus penicillin.
    Journal of the American Dental Association (1939), 1985, Volume: 111, Issue:1

    Topics: Clinical Trials as Topic; Humans; Hyperbaric Oxygenation; Mandible; Mandibular Diseases; Osteoradion

1985

Other Studies

1 other study available for penicillin g and Osteoradionecrosis

ArticleYear
[Current treatment of osteoradionecrosis].
    Revue de stomatologie et de chirurgie maxillo-faciale, 1986, Volume: 87, Issue:5

    Topics: Combined Modality Therapy; Drug Therapy, Combination; Humans; Mandible; Mandibular Diseases; Metroni

1986