penicillin g has been researched along with Neutropenia in 29 studies
Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.
Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adult neutropenic patients with lymphoma or leukaemia, and a suspected bacterial infection, were randomized for treatment with benzylpenicillin plus an aminoglycoside or meropenem." | 9.24 | Benzylpenicillin plus an aminoglycoside versus meropenem in neutropenic lymphoma and leukaemia patients with a suspected bacterial infection: a randomized, controlled trial. ( Brinch, L; Dalgaard, J; Fladhagen, T; Fløisand, Y; Hammerstrøm, J; Holte, H; Høiby, EA; Kvaløy, S; Lehmann, AK; Meyer, P; Nyquist, E; Sandvik, L; Schjesvold, FH; Skjelbakken, T; Torfoss, D, 2017) |
| "We examined the efficacy of ciprofloxacin as an empirical treatment for fever in 97 neutropenic patients in a randomized study of ciprofloxacin and benzylpenicillin versus netilmicin and piperacillin." | 9.06 | A comparative study of intravenous ciprofloxacin and benzylpenicillin versus netilmicin and piperacillin for the empirical treatment of fever in neutropenic patients. ( Jenkins, GC; Kelsey, SM; Newland, AC; Shaw, E; Wood, ME, 1990) |
| " The national recommendation in febrile neutropenia (FN) is prompt initial therapy with penicillin G plus an aminoglycoside." | 8.88 | The Norwegian experience with penicillin G plus an aminoglycoside as initial empiric therapy in febrile neutropenia; a review. ( Holte, H; Høiby, EA; Kvaløy, S; Torfoss, D, 2012) |
| "Adult neutropenic patients with lymphoma or leukaemia, and a suspected bacterial infection, were randomized for treatment with benzylpenicillin plus an aminoglycoside or meropenem." | 5.24 | Benzylpenicillin plus an aminoglycoside versus meropenem in neutropenic lymphoma and leukaemia patients with a suspected bacterial infection: a randomized, controlled trial. ( Brinch, L; Dalgaard, J; Fladhagen, T; Fløisand, Y; Hammerstrøm, J; Holte, H; Høiby, EA; Kvaløy, S; Lehmann, AK; Meyer, P; Nyquist, E; Sandvik, L; Schjesvold, FH; Skjelbakken, T; Torfoss, D, 2017) |
| "Penicillin G with an aminoglycoside is the standard initial empirical treatment in febrile neutropenia in Norway." | 5.12 | Tobramycin once versus three times daily, given with penicillin G, to febrile neutropenic cancer patients in Norway: a prospective, randomized, multicentre trial. ( Bø, K; Grøttum, K; Holte, H; Høiby, EA; Jacobsen, AB; Kvaløy, S; Lauritzsen, GF; Meyer, P; Olsen, H; Sandstad, B; Tangen, JM; Torfoss, D; Weyde, K, 2007) |
| "Evaluation of benzylpenicillin (penicillin G) effect for infection prophylaxis at the oncological patients with severe postcytostatic neutropenia was performed." | 5.10 | [Benzylpenicillin efficacy for neutropenic infection prophylaxis in patients with cancer and postcytostatic neutropenia]. ( Chimishkian, KL; Dmitrieva, NV; Larionova, VB; Minenko, SV; Ptushkin, VV; Sokolova, EN; Zhukov, NV, 2002) |
| "We examined the efficacy of ciprofloxacin as an empirical treatment for fever in 97 neutropenic patients in a randomized study of ciprofloxacin and benzylpenicillin versus netilmicin and piperacillin." | 5.06 | A comparative study of intravenous ciprofloxacin and benzylpenicillin versus netilmicin and piperacillin for the empirical treatment of fever in neutropenic patients. ( Jenkins, GC; Kelsey, SM; Newland, AC; Shaw, E; Wood, ME, 1990) |
| " Penicillin G and aminoglycoside can still be considered as first-line treatment for suspected bacteremia in neutropenic patients in Norway." | 3.74 | [Bacteremia in hematological malignant disorders]. ( Gran, FW; Hammerstrøm, J; Røym, AL, 2008) |
| "Neutropenia was accompanied by symptoms of chills and fever (5 patients), fatigue (2 patients), cough (1 patient), sore throat (1 patient), diarrhea (1 patient) and erythematous rash (1 patient)." | 1.46 | Neutropenia induced by high-dose intravenous benzylpenicillin in treating neurosyphilis: Does it really matter? ( Gao, Z; Guan, Z; Long, F; Lu, H; Peng, RR; Qi, T; Shi, M; Wu, J; Zhang, S; Zhao, W; Zhou, P, 2017) |
| "Whereas haemolytic anaemia (7) and neutropenia (12) were observed in 19 cases of the first group no such reactions were seen in the second group." | 1.27 | Adverse reactions following intravenous penicillin-G relate to degradation of the drug in vitro. ( Gubler, J; Neftel, KA; Schulthess, HK; Wälti, M, 1984) |
| "A 31-year-old white man with suspected aspiration pneumonia complicated by multiple pulmonary abscesses had profound neutropenia during a course of high-dose benzylpenicillin therapy for suspected bacterial endocarditis." | 1.27 | Profound neutropenia associated with benzylpenicillin. ( Bodensteiner, DC; Davis, JW; Helzberg, JH; Hodges, GR; Plapp, FV; Snavely, SR, 1983) |
| "Neutropenia is a potentially serious complication of parenteral benzylpenicillin administration." | 1.27 | Benzylpenicillin-induced neutropenia. ( Al-Hadramy, MS; Aman, H; Khan, MA; Omer, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (55.17) | 18.7374 |
| 1990's | 6 (20.69) | 18.2507 |
| 2000's | 4 (13.79) | 29.6817 |
| 2010's | 3 (10.34) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Torfoss, D | 4 |
| Fladhagen, T | 1 |
| Holte, H | 4 |
| Brinch, L | 1 |
| Schjesvold, FH | 1 |
| Fløisand, Y | 1 |
| Nyquist, E | 1 |
| Dalgaard, J | 1 |
| Meyer, P | 2 |
| Lehmann, AK | 1 |
| Hammerstrøm, J | 2 |
| Skjelbakken, T | 1 |
| Høiby, EA | 4 |
| Sandvik, L | 1 |
| Kvaløy, S | 4 |
| Peng, RR | 1 |
| Wu, J | 1 |
| Zhao, W | 1 |
| Qi, T | 1 |
| Shi, M | 1 |
| Guan, Z | 1 |
| Lu, H | 1 |
| Long, F | 1 |
| Gao, Z | 1 |
| Zhang, S | 1 |
| Zhou, P | 1 |
| Røym, AL | 1 |
| Gran, FW | 1 |
| Minenko, SV | 1 |
| Dmitrieva, NV | 1 |
| Chimishkian, KL | 1 |
| Zhukov, NV | 1 |
| Sokolova, EN | 1 |
| Larionova, VB | 1 |
| Ptushkin, VV | 1 |
| Tangen, JM | 2 |
| Bø, K | 1 |
| Grøttum, K | 1 |
| Weyde, K | 1 |
| Lauritzsen, GF | 1 |
| Sandstad, B | 1 |
| Jacobsen, AB | 1 |
| Olsen, H | 1 |
| Neftel, KA | 2 |
| Wälti, M | 3 |
| Schulthess, HK | 1 |
| Gubler, J | 1 |
| Snavely, SR | 1 |
| Helzberg, JH | 1 |
| Bodensteiner, DC | 1 |
| Plapp, FV | 1 |
| Davis, JW | 1 |
| Hodges, GR | 1 |
| Müller, M | 1 |
| Neftel, K | 1 |
| Hauser, S | 1 |
| Erni, J | 1 |
| Arrenbrecht, S | 1 |
| Lens, XM | 1 |
| Ginés, P | 1 |
| Sánchez-Tapias, JM | 1 |
| Murphy, MF | 1 |
| Riordan, T | 1 |
| Minchinton, RM | 1 |
| Chapman, JF | 1 |
| Amess, JA | 1 |
| Shaw, EJ | 1 |
| Waters, AH | 1 |
| Timmis, AD | 1 |
| Crofts, MA | 1 |
| Metcalfe, J | 1 |
| Monaghan, MJ | 1 |
| Sharp, J | 1 |
| Jackson, G | 1 |
| Spengler, H | 1 |
| von Felten, A | 1 |
| Weitzman, SA | 1 |
| Bürgi, H | 1 |
| de Weck, AL | 1 |
| Piérard, D | 1 |
| de Meyer, A | 1 |
| Lauwers, S | 1 |
| Berentsen, S | 1 |
| Dahl, IM | 1 |
| Ly, B | 1 |
| Myrvang, B | 1 |
| Garrod, LP | 1 |
| Romig, DA | 1 |
| Voth, DW | 1 |
| van de Leur, JJ | 1 |
| Dofferhoff, AS | 1 |
| van Turnhout, JM | 1 |
| Vollaard, EJ | 1 |
| Clasener, HA | 1 |
| Kelsey, SM | 2 |
| Wood, ME | 2 |
| Shaw, E | 2 |
| Jenkins, GC | 1 |
| Newland, AC | 2 |
| Arning, M | 1 |
| Gehrt, A | 1 |
| Aul, C | 1 |
| Runde, V | 1 |
| Hadding, U | 1 |
| Schneider, W | 1 |
| Olaison, L | 1 |
| Alestig, K | 1 |
| Kibbler, CC | 1 |
| Prentice, HG | 1 |
| Sage, RJ | 1 |
| Hoffbrand, AV | 1 |
| Brenner, MK | 1 |
| Mannan, P | 1 |
| Warner, P | 1 |
| Bhamra, A | 1 |
| Noone, P | 1 |
| Peterson, LR | 1 |
| Moody, JA | 1 |
| Fasching, CE | 1 |
| Gerding, DN | 1 |
| Pérez, I | 1 |
| Fardella, C | 1 |
| Prat, G | 1 |
| Chamorro, G | 1 |
| Casanegra, P | 1 |
| Noguera, H | 1 |
| Al-Hadramy, MS | 1 |
| Aman, H | 1 |
| Omer, A | 1 |
| Khan, MA | 1 |
| Blázquez Cabrera, JA | 1 |
| Sala Sánchez-Castillo, A | 1 |
| García Moreno, LM | 1 |
| de Castro del Pozo, S | 1 |
3 reviews available for penicillin g and Neutropenia
| Article | Year |
|---|---|
[Penicillin and aminoglycoside in febrile neutropenia].
Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Therapy, Combination; Fever; Humans; Neutropenia; Penic | 2008 |
The Norwegian experience with penicillin G plus an aminoglycoside as initial empiric therapy in febrile neutropenia; a review.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Drug Therapy, Combination; Humans; Neutropenia; Norwa | 2012 |
Chemoprophylaxis.
Topics: Colon; Drug Combinations; Drug Therapy; Endocarditis, Bacterial; Gas Gangrene; Humans; Infant, Newbo | 1975 |
6 trials available for penicillin g and Neutropenia
| Article | Year |
|---|---|
Benzylpenicillin plus an aminoglycoside versus meropenem in neutropenic lymphoma and leukaemia patients with a suspected bacterial infection: a randomized, controlled trial.
Topics: Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Female; Human | 2017 |
[Benzylpenicillin efficacy for neutropenic infection prophylaxis in patients with cancer and postcytostatic neutropenia].
Topics: Adolescent; Adult; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Agents; Bacterial I | 2002 |
Tobramycin once versus three times daily, given with penicillin G, to febrile neutropenic cancer patients in Norway: a prospective, randomized, multicentre trial.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antineoplastic Agents; Drug Therapy, Combination; Fe | 2007 |
A comparative study of intravenous ciprofloxacin and benzylpenicillin versus netilmicin and piperacillin for the empirical treatment of fever in neutropenic patients.
Topics: Adult; Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Fever; Humans; Injections, In | 1990 |
Intravenous ciprofloxacin as empirical treatment of febrile neutropenic patients.
Topics: Adult; Agranulocytosis; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Fe | 1989 |
A comparison of double beta-lactam combinations with netilmicin/ureidopenicillin regimens in the empirical therapy of febrile neutropenic patients.
Topics: Adult; Anti-Bacterial Agents; Azlocillin; Bacterial Infections; Clinical Trials as Topic; Drug Thera | 1989 |
20 other studies available for penicillin g and Neutropenia
| Article | Year |
|---|---|
Neutropenia induced by high-dose intravenous benzylpenicillin in treating neurosyphilis: Does it really matter?
Topics: Adult; Aged; Anti-Bacterial Agents; China; Female; Humans; Incidence; Male; Middle Aged; Neurosyphil | 2017 |
[Bacteremia in hematological malignant disorders].
Topics: Aminoglycosides; Anti-Bacterial Agents; Antineoplastic Agents; Bacteremia; Bacterial Infections; Dru | 2008 |
Adverse reactions following intravenous penicillin-G relate to degradation of the drug in vitro.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Drug Compounding; Drug Eruptions; Eosinophilia; Female; | 1984 |
Profound neutropenia associated with benzylpenicillin.
Topics: Adult; Agranulocytosis; Endocarditis, Bacterial; Humans; Lung Abscess; Male; Neutropenia; Penicillin | 1983 |
[Semisynthetic penicillins and cephalosporins inhibit in vitro myelopoiesis in a dose-dependent manner].
Topics: Bone Marrow Cells; Cephalosporins; Depression, Chemical; Dose-Response Relationship, Drug; Hematopoi | 1983 |
[Neutropenia caused by penicillin].
Topics: Adult; Agranulocytosis; Humans; Male; Neutropenia; Penicillin G | 1984 |
More on penicillin-induced leukopenia.
Topics: Adolescent; Adult; Cloxacillin; Female; Humans; Leukopenia; Male; Middle Aged; Neutropenia; Penicill | 1983 |
Demonstration of an immune-mediated mechanism of penicillin-induced neutropenia and thrombocytopenia.
Topics: Adult; Agranulocytosis; Autoantibodies; Autoimmune Diseases; Blood Cell Count; Blood Platelets; Fema | 1983 |
Gonococcal endocarditis with penicillin-induced bone marrow hypoplasia. Role of echocardiography.
Topics: Adolescent; Agranulocytosis; Bone Marrow; Cefuroxime; Echocardiography; Endocarditis, Bacterial; Fem | 1981 |
Neutropenia after penicillins: toxic or immune-mediated?
Topics: Adolescent; Adult; Agranulocytosis; Antibodies; Dose-Response Relationship, Drug; Female; Humans; Im | 1981 |
Antibiotic susceptibility of streptococci isolated from blood from neutropenic patients.
Topics: Bacteremia; Cephalosporins; Drug Resistance, Microbial; Humans; In Vitro Techniques; Neutropenia; Pe | 1994 |
[Empirical antibiotic treatment of patients with acute myelogenous leukemia].
Topics: Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Drug Therapy, Combination; Evaluati | 1999 |
Neutropenia. Therapy with penicillin and its congeners.
Topics: Ampicillin; Child, Preschool; Female; Humans; Neutropenia; Penicillin G; Penicillins | 1975 |
Colonisation of oropharynx with staphylococci after penicillin in neutropenic patients.
Topics: Bacteremia; Bacterial Infections; Coagulase; Colony Count, Microbial; Humans; Neutropenia; Oropharyn | 1992 |
Septicemia due to Streptococcus mitis in neutropenic patients with acute leukemia.
Topics: Adult; Cytarabine; Disseminated Intravascular Coagulation; Female; Humans; Leukemia, Myeloid, Acute; | 1990 |
A prospective study of neutropenia induced by high doses of beta-lactam antibiotics.
Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Ampicillin; Anti-Bacterial Agents; Cloxacillin; Dos | 1990 |
In vivo and in vitro activity of ciprofloxacin plus azlocillin against 12 streptococcal isolates in a neutropenic site model.
Topics: Amikacin; Animals; Azlocillin; Ciprofloxacin; Disease Models, Animal; Drug Synergism; Drug Therapy, | 1987 |
[Neutropenia induced by penicillin].
Topics: Adult; Agranulocytosis; Endocarditis, Bacterial; Humans; Leukocyte Count; Male; Neutropenia; Penicil | 1987 |
Benzylpenicillin-induced neutropenia.
Topics: Adolescent; Agranulocytosis; Endocarditis, Bacterial; Female; Humans; Male; Middle Aged; Neutropenia | 1986 |
[Neutropenia caused by penicillin].
Topics: Agranulocytosis; Female; Humans; Middle Aged; Neutropenia; Penicillin G | 1986 |