Page last updated: 2024-11-07

penicillin g and Mushroom Poisoning

penicillin g has been researched along with Mushroom Poisoning in 25 studies

Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.

Mushroom Poisoning: Poisoning from ingestion of mushrooms, primarily from, but not restricted to, toxic varieties.

Research Excerpts

ExcerptRelevanceReference
"Acute liver failure (ALF) induced by amatoxin-containing mushrooms accounts for more than 90% of deaths in patients suffering from mushroom poisoning."3.88Challenges in the early diagnosis of patients with acute liver failure induced by amatoxin poisoning: Two case reports. ( Li, Y; Lin, S; Mu, M; Yuan, L; Zeng, B, 2018)
" Amatoxin, a peptide contained in several mushroom species, accounts for the majority of severe mushroom poisonings by binding to RNA polymerase II irreversibly, leading to severe hepatonecrosis."3.74Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model. ( Betten, DP; Clark, RF; Favata, M; Hernandez, M; Richardson, WH; Riffenburgh, RH; Tanen, DA; Tong, TC, 2007)
" It is pointed out, that in a modern treatment there must be given Penicillin-G-Natrium in high dosage as early as possible, also in cases of questionableness."2.36[Mushroom poisoning in childhood]. ( Gudowski, G; Koloc, C; Rechlin, R, 1979)
" The results demonstrated that simultaneous administration of α-AMA and each of tested antidotes (BPCN, CEFT, RIFSV) effectively protected human hepatocytes; however, in the group dosed with BPCN, the highest hepatocyte viability was observed."1.35Comparative antidotal efficacy of benzylpenicillin, ceftazidime and rifamycin in cultured human hepatocytes intoxicated with α-amanitin. ( Dziędgiel, P; Gomułkiewicz, A; Magdalan, J; Ostrowska, A; Piotrowska, A; Szeląg, A, 2009)
"The electrocardiogram disclosed sinus tachycardia."1.34Renal and hepatic injury with elevated cardiac enzymes in Amanita phalloides poisoning: a case report. ( Boztok, K; Dedeoglu, E; Karcioglu, O; Soner, BC; Tuncok, Y; Unverir, P, 2007)
" The clinical picture was markedly mitigated by the early initiation of silybin therapy, in combination with penicillin and cortisone."1.27[Treatment of Amanita phalloides poisoning with silybin in combination with penicillin and cortisone]. ( Egermann, G; Hofer, JF; Mach, K; Sommer, K, 1983)
" In a comprehensive series of experiments, various dosage schedules were explored."1.26Cytochrome C as antidote in mice poisoned with the mushroom toxin alpha-amanitin. ( Floersheim, GL, 1977)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199011 (44.00)18.7374
1990's2 (8.00)18.2507
2000's5 (20.00)29.6817
2010's6 (24.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Tan, JL1
Stam, J1
van den Berg, AP1
van Rheenen, PF1
Dekkers, BGJ1
Touw, DJ1
Ye, Y1
Liu, Z1
Li, Y1
Mu, M1
Yuan, L1
Zeng, B1
Lin, S1
Onodera, M1
Garcia, J1
Carvalho, AT1
Dourado, DF1
Baptista, P1
de Lourdes Bastos, M1
Carvalho, F1
Colak, S1
Kandis, H1
Afacan, MA1
Erdogan, MO1
Gunes, H1
Kaya, E1
Akdemir, HU1
Saritas, A1
Magdalan, J2
Ostrowska, A1
Piotrowska, A2
Gomułkiewicz, A2
Szeląg, A2
Dziędgiel, P1
Sozański, T1
Dziegięl, P1
Herráez García, J1
Sánchez Fernández, A1
Contreras Sánchez, P1
Ennecker-Jans, SA1
van Daele, PL1
Blonk, MI1
Varin, DS1
van Laar, JA1
Tong, TC1
Hernandez, M1
Richardson, WH1
Betten, DP1
Favata, M1
Riffenburgh, RH1
Clark, RF1
Tanen, DA1
Unverir, P1
Soner, BC1
Dedeoglu, E1
Karcioglu, O1
Boztok, K1
Tuncok, Y1
Floersheim, GL5
Hofer, JF1
Egermann, G1
Mach, K1
Sommer, K1
Rambousek, V1
Janda, J1
Sikut, M1
Larcan, A1
Lamarche, M1
Lambert, H1
Laprevote-Heully, MC1
Patrer, JL1
Fournier, E1
Koloc, C1
Rechlin, R1
Gudowski, G1
Moroni, F1
Fantozzi, R1
Masini, E1
Mannaioni, PF1
Stenklyft, PH1
Augenstein, WL1
Neftel, K1
Keusch, G1
Cottagnoud, P1
Widmer, U1
Hany, M1
Gautschi, K1
Joos, B1
Walt, H1

Reviews

4 reviews available for penicillin g and Mushroom Poisoning

ArticleYear
Amanitin intoxication: effects of therapies on clinical outcomes - a review of 40 years of reported cases.
    Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:11

    Topics: Acetylcysteine; Alanine Transaminase; Amanita; Amanitins; Humans; Mushroom Poisoning; Penicillin G;

2022
Management of Amanita phalloides poisoning: A literature review and update.
    Journal of critical care, 2018, Volume: 46

    Topics: Acetylcysteine; Amanita; Amanitins; Antidotes; Bile Ducts; Charcoal; Diuresis; Gastric Lavage; Human

2018
[Clinical toxicology of mushroom poisoning. Amanita virosa].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2013, Volume: 26, Issue:3

    Topics: Acetylcysteine; Amanita; Amanitins; Bile; Blood Component Removal; Charcoal; Chromatography, High Pr

2013
[Mushroom poisoning in childhood].
    Kinderarztliche Praxis, 1979, Volume: 47, Issue:4

    Topics: Amanita; Amanitins; Blood Coagulation Disorders; Child; Diagnosis, Differential; Female; Hepatic Enc

1979

Other Studies

21 other studies available for penicillin g and Mushroom Poisoning

ArticleYear
Challenges in the early diagnosis of patients with acute liver failure induced by amatoxin poisoning: Two case reports.
    Medicine, 2018, Volume: 97, Issue:27

    Topics: Adult; Amanita; Amanitins; Anti-Bacterial Agents; Antioxidants; Diagnosis, Differential; Early Diagn

2018
New in silico insights into the inhibition of RNAP II by α-amanitin and the protective effect mediated by effective antidotes.
    Journal of molecular graphics & modelling, 2014, Volume: 51

    Topics: Alpha-Amanitin; Antidotes; Catalytic Domain; Ceftazidime; Humans; Hydrogen Bonding; Hydrophobic and

2014
Assessment of patients who presented to the emergency department with mushroom poisoning.
    Human & experimental toxicology, 2015, Volume: 34, Issue:7

    Topics: Adolescent; Adult; Aged; Charcoal; Emergency Service, Hospital; Female; Hemofiltration; Humans; Male

2015
Comparative antidotal efficacy of benzylpenicillin, ceftazidime and rifamycin in cultured human hepatocytes intoxicated with α-amanitin.
    Archives of toxicology, 2009, Volume: 83, Issue:12

    Topics: Alpha-Amanitin; Anti-Bacterial Agents; Antidotes; Ceftazidime; Cell Survival; Cells, Cultured; Hepat

2009
Influence of commonly used clinical antidotes on antioxidant systems in human hepatocyte culture intoxicated with alpha-amanitin.
    Human & experimental toxicology, 2011, Volume: 30, Issue:1

    Topics: Acetylcysteine; Alpha-Amanitin; Amanita; Antidotes; Antioxidants; Catalase; Cells, Cultured; Hepatoc

2011
[Fatal Lepiota brunneoincarnata poisoning].
    Anales de medicina interna (Madrid, Spain : 1984), 2002, Volume: 19, Issue:6

    Topics: Agaricales; Enzyme Inhibitors; Gastrointestinal Transit; Hemoperfusion; Humans; Mushroom Poisoning;

2002
[Amatoxin poisoning due to soup from personally picked deathcap mushrooms (Amanita phalloides)].
    Nederlands tijdschrift voor geneeskunde, 2007, Mar-31, Volume: 151, Issue:13

    Topics: Acetylcysteine; Amanita; Amanitins; Antioxidants; Drug Therapy, Combination; Female; Humans; Male; M

2007
Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model.
    Annals of emergency medicine, 2007, Volume: 50, Issue:3

    Topics: Acetylcysteine; Alanine Transaminase; Amanitins; Animals; Antidotes; Aspartate Aminotransferases; Ch

2007
Renal and hepatic injury with elevated cardiac enzymes in Amanita phalloides poisoning: a case report.
    Human & experimental toxicology, 2007, Volume: 26, Issue:9

    Topics: Amanita; Amylases; Anti-Bacterial Agents; Antidotes; Charcoal; Clinical Enzyme Tests; Creatine Kinas

2007
[Therapy of Amanita phalloides poisoning].
    Deutsche medizinische Wochenschrift (1946), 1983, Jun-03, Volume: 108, Issue:22

    Topics: Adolescent; Adult; Aged; Amanita; Amanitins; Child; Child, Preschool; Fluid Therapy; Humans; Hyperba

1983
[Treatment of Amanita phalloides poisoning with silybin in combination with penicillin and cortisone].
    Wiener klinische Wochenschrift, 1983, Apr-01, Volume: 95, Issue:7

    Topics: Adult; Alanine Transaminase; Amanita; Aspartate Aminotransferases; Drug Therapy, Combination; Female

1983
[Severe Amanita phalloides poisoning in a 7-year-old girl].
    Ceskoslovenska pediatrie, 1993, Volume: 48, Issue:6

    Topics: Acute Disease; Amanita; Child; Female; Hepatic Encephalopathy; Humans; Mushroom Poisoning; Penicilli

1993
[Experimental studies on a treatment for phalloid intoxication].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1975, Volume: 16, Issue:5

    Topics: Agaricales; Amanita; Animals; Anti-Infective Agents; Ascorbic Acid; Cytochrome c Group; Dihydrostrep

1975
Treatment of persons poisoned by mushrooms.
    Current problems in clinical biochemistry, 1977, Volume: 7

    Topics: Adult; Amanita; Child; Cytochrome c Group; Exchange Transfusion, Whole Blood; Gastric Lavage; Humans

1977
Cytochrome C as antidote in mice poisoned with the mushroom toxin alpha-amanitin.
    Current problems in clinical biochemistry, 1977, Volume: 7

    Topics: Amanita; Amanitins; Animals; Cytochrome c Group; Drug Synergism; Female; Male; Mice; Mice, Inbred CB

1977
A trend in the therapy of Amanita phalloides poisoning.
    Archives of toxicology, 1976, Oct-28, Volume: 36, Issue:2

    Topics: Adult; Alanine Transaminase; Amanita; Child; Child, Preschool; Drug Therapy, Combination; Female; Hu

1976
Chlorophyllum molybdites--severe mushroom poisoning in a child.
    Journal of toxicology. Clinical toxicology, 1990, Volume: 28, Issue:2

    Topics: Charcoal; Child; Female; Fluid Therapy; Humans; Mushroom Poisoning; Naloxone; Parenteral Nutrition,

1990
[Are cephalosporins more active than penicillin G in poisoning with the deadly Amanita?].
    Schweizerische medizinische Wochenschrift, 1988, Jan-16, Volume: 118, Issue:2

    Topics: Animals; Ceftazidime; Cells, Cultured; Cephalosporins; Chemical and Drug Induced Liver Injury; Chick

1988
Rifampicin and cysteamine protect against the mushroom toxin phalloidin.
    Experientia, 1974, Nov-15, Volume: 30, Issue:11

    Topics: Animals; Antitoxins; Chlortetracycline; Cysteamine; Cytochrome c Group; Erythromycin; Female; Guanid

1974
Antidotes to experimental -amanitin poisoning.
    Nature: New biology, 1972, Mar-29, Volume: 236, Issue:65

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antidotes; Chlorampheni

1972
Curative potencies against -amanitin poisoning by cytochrome c.
    Science (New York, N.Y.), 1972, Sep-01, Volume: 177, Issue:4051

    Topics: Animals; Antidotes; Chloramphenicol; Cytochromes; Female; Mice; Mushroom Poisoning; Mycotoxins; Peni

1972