Page last updated: 2024-11-07

penicillin g and Leukemia

penicillin g has been researched along with Leukemia in 12 studies

Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research Excerpts

ExcerptRelevanceReference
"Adult neutropenic patients with lymphoma or leukaemia, and a suspected bacterial infection, were randomized for treatment with benzylpenicillin plus an aminoglycoside or meropenem."9.24Benzylpenicillin plus an aminoglycoside versus meropenem in neutropenic lymphoma and leukaemia patients with a suspected bacterial infection: a randomized, controlled trial. ( Brinch, L; Dalgaard, J; Fladhagen, T; Fløisand, Y; Hammerstrøm, J; Holte, H; Høiby, EA; Kvaløy, S; Lehmann, AK; Meyer, P; Nyquist, E; Sandvik, L; Schjesvold, FH; Skjelbakken, T; Torfoss, D, 2017)
"Adult neutropenic patients with lymphoma or leukaemia, and a suspected bacterial infection, were randomized for treatment with benzylpenicillin plus an aminoglycoside or meropenem."5.24Benzylpenicillin plus an aminoglycoside versus meropenem in neutropenic lymphoma and leukaemia patients with a suspected bacterial infection: a randomized, controlled trial. ( Brinch, L; Dalgaard, J; Fladhagen, T; Fløisand, Y; Hammerstrøm, J; Holte, H; Høiby, EA; Kvaløy, S; Lehmann, AK; Meyer, P; Nyquist, E; Sandvik, L; Schjesvold, FH; Skjelbakken, T; Torfoss, D, 2017)
"Cancer patients with leukopenia developing infections were treated with a combination antibiotic therapy consisting of sulbenicillin and amikacin with (B) or without (A) S-sulfonated gamma-globulin."5.05[Antibiotic therapy of infections in cancer patients with leukopenia]. ( Ezaki, K; Horikoshi, N; Ikeda, K; Inagaki, J; Inoue, K; Miyamoto, H; Nakada, H; Ogawa, M; Okada, Y; Usui, N, 1983)
" Penicillin G and aminoglycoside can still be considered as first-line treatment for suspected bacteremia in neutropenic patients in Norway."3.74[Bacteremia in hematological malignant disorders]. ( Gran, FW; Hammerstrøm, J; Røym, AL, 2008)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's2 (16.67)18.2507
2000's1 (8.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Banerjee, A1
Dahiya, M1
Anand, MT1
Kumar, S1
Torfoss, D1
Fladhagen, T1
Holte, H1
Brinch, L1
Schjesvold, FH1
Fløisand, Y1
Nyquist, E1
Dalgaard, J1
Meyer, P1
Lehmann, AK1
Hammerstrøm, J2
Skjelbakken, T1
Høiby, EA1
Sandvik, L1
Kvaløy, S1
Røym, AL1
Gran, FW1
FORTEZABOVER, G1
BAGUENACANDELA, R1
JUANBORDON, A1
Inagaki, J1
Ogawa, M1
Horikoshi, N1
Ezaki, K1
Inoue, K1
Ikeda, K1
Miyamoto, H1
Usui, N1
Nakada, H1
Okada, Y1
Günther, I1
Bohnenstengel, C1
Kaben, U1
Konrad, H1
Jäger, E1
Anders, O1
Ishiyama, T1
Miyayama, T1
Sugaya, N1
Nomoto, H1
Sugimoto, M1
Wakabayashi, Y1
Shiokawa, Y1
Callaghan, JT1
Ausman, JI1
Clubb, R1
Guiot, HF2
Corel, LJ1
Vossen, JM1
Kataoka, J1
van der Meer, JW1
van den Broek, PJ1
Willemze, R1
van Furth, R1
Tattersall, MH1
Spiers, AS1
Darrell, JH1

Trials

4 trials available for penicillin g and Leukemia

ArticleYear
Benzylpenicillin plus an aminoglycoside versus meropenem in neutropenic lymphoma and leukaemia patients with a suspected bacterial infection: a randomized, controlled trial.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2017, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Female; Human

2017
[Antibiotic therapy of infections in cancer patients with leukopenia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:10

    Topics: Amikacin; Bacterial Infections; gamma-Globulins; Humans; Kanamycin; Leukemia; Leukopenia; Lymphoma;

1983
Prevalence of penicillin-resistant viridans streptococci in healthy children and in patients with malignant haematological disorders.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1994, Volume: 13, Issue:8

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Leukemia;

1994
Prevention of viridans-group streptococcal septicemia in oncohematologic patients: a controlled comparative study on the effect of penicillin G and cotrimoxazole.
    Annals of hematology, 1992, Volume: 64, Issue:6

    Topics: Agranulocytosis; Antineoplastic Agents; Bacteremia; Drug Hypersensitivity; Drug Interactions; Drug R

1992

Other Studies

8 other studies available for penicillin g and Leukemia

ArticleYear
Inhibition of proliferation of cervical and leukemic cancer cells by penicillin G.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Biomarkers, Tumor; Blotting, Western; Cell Proliferation; Cells, Cul

2013
[Bacteremia in hematological malignant disorders].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2008, Aug-14, Volume: 128, Issue:15

    Topics: Aminoglycosides; Anti-Bacterial Agents; Antineoplastic Agents; Bacteremia; Bacterial Infections; Dru

2008
[A CASE OF ACUTE PARAMYELOBLASTIC PROMYELOCYTIC LEUCOSIS WITH TRISOMOC D, HAPLOSOMIC C AND HAPLOSOMIC G BLOOD CELLS].
    Medicina espanola, 1963, Volume: 50

    Topics: Blood Cells; Bone Marrow Examination; Chromosome Aberrations; Chromosome Disorders; Genetics, Medica

1963
[Results of prevention of infection with selective decontamination of the digestive tract in the treatment of leukemia].
    Folia haematologica (Leipzig, Germany : 1928), 1984, Volume: 111, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Ampicillin; Bacterial Infections; Cephalothin; Digestive Sys

1984
[Clinical investigation of combined therapy (cefotiam, sulbenicillin and cefsulodin) against infections complicated by acute leukemia].
    The Japanese journal of antibiotics, 1983, Volume: 36, Issue:1

    Topics: Acute Disease; Adult; Bacterial Infections; Cefotaxime; Cefotiam; Cefsulodin; Cephalosporins; Drug E

1983
CSF perfusion to treat intraventricular penicillin toxicity.
    Archives of neurology, 1981, Volume: 38, Issue:6

    Topics: Adult; Cerebrospinal Fluid; Humans; Injections, Intraventricular; Leukemia; Male; Meningeal Neoplasm

1981
[On the safety of sulbenicillin administration to infections associated with acute leukaemia (author's transl)].
    The Japanese journal of antibiotics, 1979, Volume: 32, Issue:9

    Topics: Adult; Aged; Aspartate Aminotransferases; Bacterial Infections; Electrolytes; Female; gamma-Glutamyl

1979
Initial therapy with combination of five antibiotics in febrile patients with leukaemia and neutropenia.
    Lancet (London, England), 1972, Jan-22, Volume: 1, Issue:7743

    Topics: Administration, Oral; Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Bacterial Infections

1972