penicillin g and Infections, Pseudomonas studies

Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.

Research Excerpts

Excerpt	Relevance	Reference
"Preseptal cellulitis has a typically benign course when treated with antibiotics, the clinical course depending on age of the patient, aetiology and the causative organism."	1.29	Pre-septal cellulitis--varied clinical presentations. ( Hans, R; Mehra, AK; Rao, VA, 1996)
"Bacterial meningitis is not considered a separate disease entity but a complication of bacteremia and sepsis."	1.27	[Chemotherapy of severe bacterial infections in pediatrics]. ( Guggenbichler, JP, 1983)
"Penicillin G potassium was ineffective in the MTCM system, and gentamicin reagent solution was not uniformly effective against a gentamicin-sensitive strain of P aeruginosa."	1.27	Modified tissue culture medium for corneal storage I. Investigation of the effect of antibiotics on bacterial contamination. ( Jones, DB; Liesegang, TJ; Robinson, N, 1984)
"Gentamicin was nearly as active as polymyxin, all but 2 of the 141 strains tested with the diluted inoculum being inhibited by 6."	1.25	Susceptibility of recent isolates of Pseudomonas aeruginosa to gentamicin, polymyxin, and five penicillins, with observations on the pyocin and immunotypes of the strains. ( Adler, JL; Finland, M, 1971)

Timeframe	Studies, this research(%)	All Research%
pre-1990	50 (86.21)	18.7374
1990's	2 (3.45)	18.2507
2000's	2 (3.45)	29.6817
2010's	4 (6.90)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Edwards, ML	1
Bambury, RE	1
Ritter, HW	1
Marchiaro, P	1
Tomatis, PE	1
Mussi, MA	1
Pasteran, F	1
Viale, AM	1
Limansky, AS	1
Vila, AJ	1
Juan, C	1
Beceiro, A	1
Gutiérrez, O	1
Albertí, S	1
Garau, M	1
Pérez, JL	1
Bou, G	1
Oliver, A	1
Doublet, B	1
Robin, F	1
Casin, I	1
Fabre, L	1
Le Fleche, A	1
Bonnet, R	1
Weill, FX	1
Poirel, L	2
Docquier, JD	1
De Luca, F	1
Verlinde, A	1
Ide, L	1
Rossolini, GM	1
Nordmann, P	2
Kotsakis, SD	1
Papagiannitsis, CC	1
Tzelepi, E	1
Legakis, NJ	1
Miriagou, V	1
Tzouvelekis, LS	1
Rodríguez-Martínez, JM	1
Al Naiemi, N	1
Debets-Ossenkopp, YJ	1
ANDERSON, KN	1
KENNEDY, RP	1
PLORDE, JJ	1
SHULMAN, JA	1
PETERSDORF, RG	1
SHILO, M	1
SHIODA, K	1
YAMADA, K	1
MIKI, F	1
AZUMA, T	1
HERNADI, F	1
VALYI NAGY, T	1
WEINSTEIN, L	2
LERNER, PI	1
CHEW, WH	1
COLLEY, EW	1
FRANKEL, HL	1
Guggenbichler, JP	1
Moss, RB	1
Babin, S	1
Hsu, YP	1
Blessing-Moore, J	1
Lewiston, NJ	1
Adkinson, NF	1
Pienkowski, MM	1
Liesegang, TJ	1
Robinson, N	1
Jones, DB	1
Preheim, LC	1
Sanders, WE	1
Rao, VA	1
Hans, R	1
Mehra, AK	1
Cade, A	1
Denton, M	1
Brownlee, KG	1
Todd, N	1
Conway, SP	1
Chico Rizzo, E	1
Kondo, M	1
Tsuchiya, K	3
Lebrun, M	1
de Repentigny, J	1
Mathieu, LG	1
Montanari, A	1
Borghi, L	1
Curti, A	1
Canali, M	1
Biggi, A	1
Mutti, A	1
Novarini, A	1
Perinotto, P	1
Wise, R	1
Klastersky, J	1
Hensgens, C	1
Meunier-Carpentier, F	1
Brook, I	1
Walker, RI	1
Baum, J	1
Badenoch, PR	1
Hay, GJ	1
McDonald, PJ	1
Coster, DJ	1
Pozdniakova, VP	1
Kuznetsova, SM	1
Lobuseva, AN	1
Fomina, IP	1
Waisbren, BA	1
Tattersall, MH	1
Spiers, AS	1
Darrell, JH	1
Hughes, JP	1
Loy, RG	1
Asbury, AC	1
Burd, HE	1
Kolb, R	1
Rotter, M	1
Farrar, WE	1
Nagatomo, H	1
Kakizaki, M	1
Cockett, AT	1
Adey, WR	1
Roberts, AP	1
Nakazawa, S	1
Nishino, T	1
Otsuki, M	1
Nakao, M	1
Nomura, T	1
Plaue, R	1
Neff, G	1
Mössner, G	1
Guenther, M	1
FitzPatrick, FK	1
Bladzinski, J	1
Adler, JL	1
Finland, M	1
Yamazaki, T	1
Mel'nikova, VM	1
de Weck, AL	1
Girard, JP	1
Tauchnitz, C	1
Ellorhaoui, M	1
Wilson, HD	1
Eichenwald, HF	1
Takayasu, H	1
Nishimura, Y	1
Kawada, Y	1
Miyamura, Y	1
Ruedy, J	1
Liwski, R	1
Gietko, G	1
Tourkantonis, A	1
Heinze, V	1
Essery, JM	1
Braginskaia, PS	1
Shneerson, AN	1
Rezvan, SP	1
Meyers, BR	1
Sabbaj, J	1
Rudzit, EA	1
Lisitsa, LI	1
Tindel, JR	1
Crowder, JG	1
Standiford, HC	1
Jordan, MC	1
Kirby, WM	1

Trial			Phase	Enrollment	Study Type	Start Date	Status
A Single Arm 48-Week Follow-on Safety Study to the Core Study (A Multicentre, Multinational, Open-Label, Randomised, Parallel Group Clinical Trial of Tobrineb®/Actitob®/Bramitob® (Tobramycin Solution for Nebulisation, 300mg Twice Daily in 4mL Unit Dose Vi[NCT01111383]			Phase 3	209 participants (Actual)	Interventional	2009-09-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
[ROLE OF ANTIBIOTICS IN THE TREATMENT OF ACUTE RADIATION SYNDROME]. Orvosi hetilap, 1963, May-19, Volume: 104 Topics: Acute Radiation Syndrome; Anti-Bacterial Agents; Chloramphenicol; Chlortetracycline; Diphtheria; Ent	1963
Antibiotics in the treatment of burns. The Surgical clinics of North America, 1970, Volume: 50, Issue:6 Topics: Adult; Anti-Bacterial Agents; Burns; Child; Chloramphenicol; Clostridium Infections; Enterobacter; g	1970
Sepsis neonatorum. Pediatric clinics of North America, 1974, Volume: 21, Issue:3 Topics: Ampicillin; Bacteria; Bacterial Infections; Enterobacteriaceae; Gentamicins; Humans; Infant, Newborn	1974
[Experimental pyelonephritis, chemotherapeutic studies (review of the literature)]. Farmakologiia i toksikologiia, 1971, Volume: 34, Issue:2 Topics: Acute Disease; Ampicillin; Animals; Anti-Bacterial Agents; Chloramphenicol; Chronic Disease; Coryneb	1971

Article	Year
Comparative effectiveness of combinations of amikacin with penicillin G and amikacin with carbenicillin in gram-negative septicemia: double-blind clinical trial. The Journal of infectious diseases, 1976, Volume: 134 SUPPL Topics: Amikacin; Bacterial Infections; Blood Bactericidal Activity; Carbenicillin; Clinical Trials as Topic	1976
Specific inhibition of allergic reactions to penicillin in man by a monovalent hapten. II. Clinical studies. International archives of allergy and applied immunology, 1972, Volume: 42, Issue:6 Topics: Adult; Aged; Allergens; Antibodies; Bronchopneumonia; Carbuncle; Child; Child, Preschool; Cholecysti	1972
[Treatment with carbenicillin (Pyopen) of severe general infectious and pyelonephritis due to Pseudomonas aeruginosa and Proteus]. Polskie Archiwum Medycyny Wewnetrznej, 1969, Volume: 43, Issue:3 Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Escherichia coli Infections; Female; Humans; Inje	1969

penicillin g and Infections, Pseudomonas

Research Excerpts

Research

Studies (58)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Article	Year
Beta-lactam antibiotics with N-oxide side chains. 1. Quinoxaline N-oxides. Journal of medicinal chemistry, 1976, Volume: 19, Issue:2 Topics: Animals; Cyclic N-Oxides; Mice; Microbial Sensitivity Tests; Penicillins; Proteus Infections; Proteu	1976
Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6 Topics: beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Binding Sites; Escherichia coli; Humans; Kine	2008
Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactam Resistanc	2008
Molecular and biochemical characterization of the natural chromosome-encoded class A beta-lactamase from Pseudomonas luteola. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Catheters, Indwelling; Chromosomes, Bac	2010
BEL-2, an extended-spectrum beta-lactamase with increased activity toward expanded-spectrum cephalosporins in Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Belgium; beta-Lactamases; Cephalosporinase; Cephalosporins; Cross Infection; Escherichia coli; Genes	2010
GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3 Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; beta-Lactams; Cephalosporins; Genetic Variation;	2010
Characterization of DIM-1, an integron-encoded metallo-beta-lactamase from a Pseudomonas stutzeri clinical isolate in the Netherlands. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6 Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA, Ba	2010
EFFECTIVENESS OF AMPICILLIN AGAINST GRAM-NEGATIVE BACTERIA. IN VITRO AND IN VIVO STUDIES OF A NEW ANTIBIOTIC. JAMA, 1964, Feb-22, Volume: 187 Topics: Ampicillin; Anti-Bacterial Agents; Bacteriological Techniques; Chloramphenicol; Drug Resistance; Dru	1964
THE USE OF LEVAN-ENHANCED DERMAL INFECTIONS IN RABBITS IN THE STUDY OF IN VIVO ACTIVITY OF ANTIBIOTIC SUBSTANCES. British journal of experimental pathology, 1964, Volume: 45 Topics: Anti-Bacterial Agents; Corynebacterium diphtheriae; Dermatology; Dextrans; Erythromycin; Fructans; I	1964
[BACTERIAL ENDOCARDITIS; THE PRESENT STATUS AND TREATMENT]. [Sogo rinsho] Clinic all-round, 1964, Volume: 13 Topics: Amphotericin B; Anti-Bacterial Agents; Chloramphenicol; Colistin; Drug Resistance; Drug Resistance,	1964
CLINICAL AND BACTERIOLOGIC STUDIES OF THE EFFECT OF "MASSIVE" DOSES OF PENICILLIN G ON INFECTIONS CAUSED BY GRAM-NEGATIVE BACILLI. The New England journal of medicine, 1964, Sep-10, Volume: 271 Topics: Alcaligenes; Bacteriological Techniques; Cholangitis; Enterobacter aerogenes; Enterobacteriaceae; Es	1964
PENICILLIN G--TREATMENT OF URINARY INFECTION IN PARAPLEGIA. Paraplegia, 1964, Volume: 2 Topics: Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Enterobacteriaceae; Escherichia coli Infe	1964
[Chemotherapy of severe bacterial infections in pediatrics]. Wiener klinische Wochenschrift. Supplementum, 1983, Volume: 142 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Cefotaxime; Cephalosporins; Clindamyci	1983
Allergy to semisynthetic penicillins in cystic fibrosis. The Journal of pediatrics, 1984, Volume: 104, Issue:3 Topics: Adolescent; Adult; Benzeneacetamides; Carbenicillin; Child; Cystic Fibrosis; Drug Hypersensitivity;	1984
Escalating infections versus penicillin allergy. Hospital practice (Office ed.), 1983, Volume: 18, Issue:10 Topics: Adult; Cross Reactions; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Male; Mediastin	1983
Modified tissue culture medium for corneal storage I. Investigation of the effect of antibiotics on bacterial contamination. Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:4 Topics: Anti-Bacterial Agents; Cornea; Culture Media; Gentamicins; Humans; Penicillin G; Pseudomonas Infecti	1984
Nosocomial pneumonia. Comprehensive therapy, 1981, Volume: 7, Issue:6 Topics: Aminoglycosides; Cephalosporins; Cross Infection; Enterobacter; Enterobacteriaceae Infections; Esche	1981
Pre-septal cellulitis--varied clinical presentations. Indian journal of ophthalmology, 1996, Volume: 44, Issue:4 Topics: Adolescent; Adult; Cellulitis; Child; Child, Preschool; Conjunctiva; Drug Therapy, Combination; Eye	1996
Acute bronchopulmonary infection due to Streptococcus milleri in a child with cystic fibrosis. Archives of disease in childhood, 1999, Volume: 80, Issue:3 Topics: Acute Disease; Child; Colistin; Cystic Fibrosis; Drug Therapy, Combination; Female; Floxacillin; Hum	1999
Antibiotic treatment of respiratory sepsis. Antibiotics and chemotherapy, 1976, Volume: 21 Topics: Ampicillin; Anti-Bacterial Agents; Carbenicillin; Cephalosporins; Chloramphenicol; Cloxacillin; Fosf	1976
Comparative in vivo activities of cefsulodin, sulbenicillin, and gentamicin against Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 1978, Volume: 14, Issue:1 Topics: Animals; Cephalosporins; Gentamicins; Mice; Penicillin G; Penicillin Resistance; Pseudomonas Infecti	1978
[Diminution of the antibacterial activity of antibiotics in cultures and in experimental mixed infections]. Canadian journal of microbiology, 1978, Volume: 24, Issue:2 Topics: Animals; Anti-Bacterial Agents; Culture Media; Cycloserine; Mice; Penicillin G; Pseudomonas aerugino	1978
[Role of kidney function in the pharmacokinetics of a new semisynthetic penicillin (sulbenicillin)]. La Clinica terapeutica, 1979, Apr-30, Volume: 89, Issue:2 Topics: Adult; Aged; Evaluation Studies as Topic; Humans; Male; Middle Aged; Penicillin G; Proteus Infection	1979
Use of antibiotics. Penicillins. British medical journal, 1978, Jun-24, Volume: 1, Issue:6128 Topics: Drug Combinations; Humans; Penicillin G; Penicillin Resistance; Penicillinase; Penicillins; Proteus	1978
The relationship between Fusobacterium species and other flora in mixed infection. Journal of medical microbiology, 1986, Volume: 21, Issue:2 Topics: Abscess; Animals; Bacteroides Infections; Escherichia coli Infections; Fusobacterium; Fusobacterium	1986
Therapy for ocular bacterial infection. Transactions of the ophthalmological societies of the United Kingdom, 1986, Volume: 105 ( Pt 1) Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Bacitracin; Bacterial Infections; Blepharitis; Cellu	1986
A rat model of bacterial keratitis. Effect of antibiotics and corticosteroid. Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:5 Topics: Animals; Bacterial Infections; Cephalosporins; Cephradine; Disease Models, Animal; Drug Therapy, Com	1985
[Methods of evaluating the efficacy of combinations of aminoglycosides with penicillins and their value for the possibility of predicting the therapeutic effect in patients]. Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1985, Volume: 30, Issue:5 Topics: Animals; Azlocillin; Carbenicillin; Drug Combinations; Drug Therapy, Combination; Gentamicins; Human	1985
Initial therapy with combination of five antibiotics in febrile patients with leukaemia and neutropenia. Lancet (London, England), 1972, Jan-22, Volume: 1, Issue:7743 Topics: Administration, Oral; Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Bacterial Infections	1972
The occurrence of Pseudomonas in the reproductive tract of mares and its effect on fertility. The Cornell veterinarian, 1966, Volume: 56, Issue:4 Topics: Animals; Anti-Infective Agents, Local; Colistin; Dihydrostreptomycin Sulfate; Female; Genital Diseas	1966
[Epidemiology of the urinary tract infection in patients with prolonged catheterization in an intensive care unit]. Der Anaesthesist, 1973, Volume: 22, Issue:5 Topics: Ampicillin; Enterobacteriaceae Infections; Escherichia coli Infections; Follow-Up Studies; Germany,	1973
When to use two or more antibiotics. American family physician, 1973, Volume: 8, Issue:1 Topics: Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Bacteroides Infections; Drug Antagonism; En	1973
Combined action of sulbenicillin and gentamicin. The Journal of antibiotics, 1974, Volume: 27, Issue:3 Topics: Animals; Drug Synergism; Drug Therapy, Combination; Gentamicins; Injections, Subcutaneous; Male; Mic	1974
Maintenance of urinary asepsis in subhuman primates during chronic catheter drainage. The Journal of urology, 1974, Volume: 112, Issue:2 Topics: Animals; Antisepsis; Haplorhini; Hydrogen-Ion Concentration; Male; Penicillin G; Proteus Infections;	1974
Bacteriological studies on the combined action of aminoglycoside antibiotics and synthetic penicillins against Pseudomonas aeruginosa. The Journal of antibiotics, 1974, Volume: 27, Issue:12 Topics: Animals; Carbenicillin; Drug Combinations; Gentamicins; Mice; Penicillin G; Pseudomonas aeruginosa;	1974
[The incidence of infection in orthopedic and traumatologic operations (author's transl)]. Zeitschrift fur Orthopadie und ihre Grenzgebiete, 1973, Volume: 111, Issue:6 Topics: Arthritis, Infectious; Cephalosporins; Cloxacillin; Dicloxacillin; Germany, West; Humans; Kanamycin;	1973
[Chemotherapy and chemoprophylaxis of surgical infections]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1967, Volume: 38, Issue:4 Topics: Bacteria; Cephalosporins; Chloramphenicol; Drug Antagonism; Drug Incompatibility; Humans; Infections	1967
Pyelonephritis in the mouse. 3. Therapeutic experiments. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 127, Issue:4 Topics: Ampicillin; Animals; Anti-Infective Agents; Chloramphenicol; Immunization, Passive; Kanamycin; Mice;	1968
Susceptibility of recent isolates of Pseudomonas aeruginosa to gentamicin, polymyxin, and five penicillins, with observations on the pyocin and immunotypes of the strains. Applied microbiology, 1971, Volume: 22, Issue:5 Topics: Ampicillin; Bacteriocins; Carbenicillin; Gentamicins; Humans; Microbial Sensitivity Tests; Penicilli	1971
In vivo antibacterial activity of disodium -sulfobenzylpenicillin. The Journal of antibiotics, 1971, Volume: 24, Issue:9 Topics: Administration, Oral; Ampicillin; Animals; Bacterial Infections; Carbenicillin; Escherichia coli Inf	1971
[Use of antibiotics in traumatology and orthopedics]. Antibiotiki, 1974, Volume: 19, Issue:11 Topics: Acute Disease; Anti-Bacterial Agents; Bone Diseases; Clindamycin; Drug Therapy, Combination; Humans;	1974
[Antibacterial chemotherapy of the chronic bronchitis syndrome]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Feb-01, Volume: 29, Issue:3 Topics: Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Bronchitis; Carbenicillin; Cephalosporins;	1974
[Experimental and clinical evaluation of Sulbenicillin in urinary infection caused by Proteus and Pseudomonas aeruginosa]. Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:11 Topics: Adolescent; Adult; Aged; Child; Female; Humans; Male; Middle Aged; Penicillin G; Proteus Infections;	1972
Antibiotic treatment of septic arthritis. Clinical orthopaedics and related research, 1973, Issue:96 Topics: Ampicillin; Anti-Bacterial Agents; Arthritis, Infectious; Cloxacillin; Gentamicins; Gonorrhea; Haemo	1973
Clinical conference: bacterial endocarditis. Southern medical journal, 1974, Volume: 67, Issue:1 Topics: Adolescent; Ampicillin; Carbenicillin; Cephalothin; Drug Therapy, Combination; Endocarditis, Bacteri	1974
[Carbencillin in Pseudomonas aeruginosa infections]. Deutsche medizinische Wochenschrift (1946), 1969, Apr-25, Volume: 94, Issue:17 Topics: Humans; Injections, Intravenous; Penicillin G; Pseudomonas aeruginosa; Pseudomonas Infections	1969
Preparation and antibacterial activity of alpha-(5-tetrazolyl) benzylpenicillin. Journal of medicinal chemistry, 1969, Volume: 12, Issue:4 Topics: Ampicillin; Animals; Azoles; Bacteriological Techniques; Mice; Penicillin G; Penicillins; Proteus; P	1969
[Development of resistance to ampicillin in gram negative microorganisms in vitro]. Antibiotiki, 1969, Volume: 14, Issue:9 Topics: Ampicillin; Chloramphenicol; Escherichia coli; Escherichia coli Infections; Humans; In Vitro Techniq	1969
Bacteriological, pharmacological, and clinical studies of carbenicillin. Archives of internal medicine, 1970, Volume: 125, Issue:2 Topics: Adult; Aged; Anti-Bacterial Agents; Bacteria; Enterobacteriaceae; Escherichia coli; Female; Haemophi	1970
Septic arthritis due to Pseudomonas aeruginosa. JAMA, 1971, Oct-25, Volume: 218, Issue:4 Topics: Adult; Amputation, Surgical; Arthritis, Infectious; Diabetes Complications; Foot Diseases; Humans; L	1971
Clinical pharmacology of carbenicillin compared with other penicillins. The Journal of infectious diseases, 1970, Volume: 122 Topics: Ampicillin; Anti-Bacterial Agents; Benzene Derivatives; Humans; Injections, Intravenous; Kidney; Liv	1970