penicillin g has been researched along with Disease Models, Animal in 87 studies
Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The current standard of care for inhalational anthrax postexposure prophylaxis is ciprofloxacin therapy twice daily for 60 days." | 7.74 | Efficacy of oritavancin in a murine model of Bacillus anthracis spore inhalation anthrax. ( Arhin, FF; Bassett, A; Bassett, J; Heine, HS; Ivins, BE; Lehoux, D; Miller, L; Moeck, G; Parr, TR, 2008) |
| "The effects of enflurane on three epilepsy models were studied in cats." | 7.67 | Anticonvulsant actions of enflurane on epilepsy models in cats. ( Mori, K; Oshima, E; Shingu, K; Urabe, N, 1985) |
| "Using a rabbit sterile peritonitis model, we compared the penetration of intravenously administered amikacin, gentamicin, and penicillin G into peritoneal exudate." | 7.65 | Comparative penetration of amikacin, gentamicin, and penicillin g into exudate fluid in experimental sterile peritonitis. ( MacGregor, RR, 1977) |
| "This paper aims to validate if intrapancreatic injection of penicillin G can enhance hardness and suture holding capacity (SHC) of the pancreas through prompting the fibrosis process." | 3.96 | A Novel Way of Preventing Postoperative Pancreatic Fistula by Directly Injecting Profibrogenic Materials into the Pancreatic Parenchyma. ( Ahn, J; Cho, SJ; Choi, HJ; Hong, HE; Hong, TH; Hwang, KS; Jung, JK; Jung, KY; Kim, KH; Kim, OH; Kim, SJ; Lee, SC; Lee, TY; Rim, E; Seo, H; Song, JS, 2020) |
| " The current standard of care for inhalational anthrax postexposure prophylaxis is ciprofloxacin therapy twice daily for 60 days." | 3.74 | Efficacy of oritavancin in a murine model of Bacillus anthracis spore inhalation anthrax. ( Arhin, FF; Bassett, A; Bassett, J; Heine, HS; Ivins, BE; Lehoux, D; Miller, L; Moeck, G; Parr, TR, 2008) |
| " Amatoxin, a peptide contained in several mushroom species, accounts for the majority of severe mushroom poisonings by binding to RNA polymerase II irreversibly, leading to severe hepatonecrosis." | 3.74 | Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model. ( Betten, DP; Clark, RF; Favata, M; Hernandez, M; Richardson, WH; Riffenburgh, RH; Tanen, DA; Tong, TC, 2007) |
| "Five antimicrobial drugs (ciprofloxacin, clindamycin, imipenem, penicillin G, and rifampin) were examined for therapeutic efficacy in a murine model gas gangrene due to Clostridium perfringens type A, following infection with large bacterial inocula." | 3.67 | Chemotherapy of experimental (murine) Clostridium perfringens type A gas gangrene. ( Traub, WH, 1988) |
| "The effects of enflurane on three epilepsy models were studied in cats." | 3.67 | Anticonvulsant actions of enflurane on epilepsy models in cats. ( Mori, K; Oshima, E; Shingu, K; Urabe, N, 1985) |
| "Using a rabbit sterile peritonitis model, we compared the penetration of intravenously administered amikacin, gentamicin, and penicillin G into peritoneal exudate." | 3.65 | Comparative penetration of amikacin, gentamicin, and penicillin g into exudate fluid in experimental sterile peritonitis. ( MacGregor, RR, 1977) |
| " Clindamycin and tetracycline were the most effective in preventing the formation of abscesses." | 3.65 | Chemotherapy of an experimental Bacteroides fragilis infection in mice. ( Nitzan, D; Walker, CB; Wilkins, TD, 1977) |
| " Pentylenetetrazol was given intraveneously in 50-mg increments or 4% enflurane was inspired until grand mal seizures occurred spontaneously or were triggered by photic or auditory stimuli." | 3.65 | Effects of acute and chronic paleocerebellar stimulation on experimental models of epilepsy in the cat: studies with enflurane, pentylenetetrazol, penicillin, and chloralose. ( Bickford, RG; Burchiel, KJ; Myers, RR; Stockard, JJ, 1975) |
| " We determined that when mice were administered intermittent subtherapeutic dosing of benzylpenicillin, the strain with a Pro601Leu amino acid replacement in PBP2X that confers reduced β-lactam susceptibility in vitro was more fit, as assessed by the magnitude of colony-forming units recovered from disease tissue." | 1.56 | A Single Amino Acid Replacement in Penicillin-Binding Protein 2X in Streptococcus pyogenes Significantly Increases Fitness on Subtherapeutic Benzylpenicillin Treatment in a Mouse Model of Necrotizing Myositis. ( Musser, JM; Olsen, RJ; Zhu, L, 2020) |
| "Incidence rates of Barrett's esophagus and adenocarcinoma in each group were evaluated by histological analysis." | 1.43 | Alteration of Esophageal Microbiome by Antibiotic Treatment Does Not Affect Incidence of Rat Esophageal Adenocarcinoma. ( Arakawa, T; Fujiwara, Y; Gi, M; Nagami, Y; Sawada, A; Shiba, M; Tanaka, F; Tanigawa, T; Tominaga, K; Wanibuchi, H; Watanabe, T; Yamagami, H, 2016) |
| "Atorvastatin treatment reduced spike frequencies and amplitudes significantly throughout the experiment." | 1.42 | HMG-CoA reductase inhibitor rosuvastatin improves abnormal brain electrical activity via mechanisms involving eNOS. ( Caglayan, AB; Caglayan, B; Demirci, S; Dogan, A; Ekimci, N; Ethemoglu, MS; Kilic, E; Kilic, U; Oztezcan, S; Sahin, F; Seker, FB; Yilmaz, B, 2015) |
| " Synergism was reported and therapeutic efficacy was significantly enhanced when DM3 was formulated in combination with penicillin (PEN)." | 1.42 | In vivo efficacy and molecular docking of designed peptide that exhibits potent antipneumococcal activity and synergises in combination with penicillin. ( Hassan, MA; Isa, DM; Le, CF; Lee, VS; Sekaran, SD; Yusof, MY, 2015) |
| "Penicillin G was administered intracortically into superficial layers of the left sensorimotor cortex and EDs were induced." | 1.38 | Focal brain cooling terminates the faster frequency components of epileptic discharges induced by penicillin G in anesthetized rats. ( Fujii, M; He, Y; Ichikawa, T; Inoue, T; Kida, H; Maruta, Y; Nomura, S; Saito, T; Suzuki, M; Taniguchi, K; Yamakawa, T, 2012) |
| " The sigmoid maximum-threshold-of-efficacy (E(max)) model fit the survival data, in which the free-drug area under the concentration-time curve (fAUC)/MIC ratio, the maximum concentration of free drug in plasma (fC(max))/MIC ratio, and the cumulative percentage of a 24-h period that the free-drug concentration exceeds the MIC under steady-state pharmacokinetic conditions (f %T(MIC)) were each evaluated." | 1.36 | Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. ( Ambrose, PG; Bassett, J; Beaudry, A; Bhavnani, SM; Critchley, I; Gill, SC; Heine, HS; Janjic, N; Li, J; Miller, L; Rubino, CM; Stone, KC, 2010) |
| "This study was designed to evaluate the penicillin-induced epilepsy model in terms of dose-response relationship of penicillin used to induce epilepsy seizure on hippocampal neuron number and hippocampal volume in Sprague-Dawley rats." | 1.35 | Penicillin-induced epilepsy model in rats: dose-dependant effect on hippocampal volume and neuron number. ( Adiguzel, E; Akdogan, I; Ozdemir, MB; Sahiner, M; Tufan, AC; Yilmaz, I, 2008) |
| "Canine myocardial infarcts were created by coronary ligation." | 1.35 | Epicardial border zone overexpression of skeletal muscle sodium channel SkM1 normalizes activation, preserves conduction, and suppresses ventricular arrhythmia: an in silico, in vivo, in vitro study. ( Anyukhovsky, EP; Chen, M; Clausen, C; Cohen, IS; Danilo, P; Duffy, HS; Kelly, C; Kumari, S; Lau, DH; Lu, J; Robinson, RB; Rosen, MR; Rosen, TS; Shlapakova, IN; Sosunov, EA; Szabolcs, MJ, 2009) |
| "The correlation between pharmacokinetic parameters and the in-vivo effect of antibiotics in relation to bacterial growth phases was evaluated using the mouse peritonitis model with a penicillin-resistant pneumococcus." | 1.30 | Pharmacodynamics of penicillin are unaffected by bacterial growth phases of Streptococcus pneumoniae in the mouse peritonitis model. ( Espersen, F; Frimodt-Møller, N; Knudsen, JD, 1998) |
| "Limbic seizures occurred frequently during the initial 5 hours but subsided completely within 3 days." | 1.28 | [Acute effect of penicillin G on feline models of focal epilepsy]. ( Kaijima, M; Kunimoto, M; Tanaka, S; Tanaka, T; Yonemasu, Y, 1989) |
| "3%; when the dosage was increased to 600,000 U/day, the mortality ws 37." | 1.26 | Is penicillin alone effective in enterococcal endocarditis? An experimental study in rabbits. ( Bach, VT; Mandal, AK; Rambhatla, K; Thadepalli, H, 1981) |
| "Phenytoin and diazepam were maximally effective at concentrations of 20 microgram/ml and 3-4 microgram/ml, respectively, in good agreement with their effective concentrations in clinical practice." | 1.26 | The hippocampal slice: a system for studying the pharmacology of seizures and for screening anticonvulsant drugs. ( Hoffer, BJ; Oliver, AP; Wyatt, RJ, 1977) |
| " Penicillin was given at a daily intramuscular dosage of 40,000 units procaine penicillin G beginning 2 days prior to exposure and continuing through the third day after exposure." | 1.26 | Protective effect of prophylactic penicillin on splenectomized mice exposed to an aerosolized suspension of type III Streptococcus pneumoniae. ( Bolton, E; Chalmer, BJ; Coil, JA; Dickerman, JD; Jakab, GJ, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 58 (66.67) | 18.7374 |
| 1990's | 3 (3.45) | 18.2507 |
| 2000's | 12 (13.79) | 29.6817 |
| 2010's | 12 (13.79) | 24.3611 |
| 2020's | 2 (2.30) | 2.80 |
| Authors | Studies |
|---|---|
| Mata, R | 1 |
| Martínez, E | 1 |
| Bye, R | 1 |
| Morales, G | 1 |
| Singh, MP | 1 |
| Janso, JE | 1 |
| Maiese, WM | 1 |
| Timmermann, B | 1 |
| Ohtsuki, S | 1 |
| Kikkawa, T | 1 |
| Mori, S | 1 |
| Hori, S | 1 |
| Takanaga, H | 1 |
| Otagiri, M | 1 |
| Terasaki, T | 1 |
| Heine, HS | 2 |
| Bassett, J | 2 |
| Miller, L | 2 |
| Bassett, A | 1 |
| Ivins, BE | 1 |
| Lehoux, D | 1 |
| Arhin, FF | 1 |
| Parr, TR | 1 |
| Moeck, G | 1 |
| Gill, SC | 1 |
| Rubino, CM | 1 |
| Ambrose, PG | 1 |
| Bhavnani, SM | 1 |
| Beaudry, A | 1 |
| Li, J | 1 |
| Stone, KC | 1 |
| Critchley, I | 1 |
| Janjic, N | 1 |
| Seebacher, W | 1 |
| Wolkinger, V | 1 |
| Faist, J | 1 |
| Kaiser, M | 1 |
| Brun, R | 1 |
| Saf, R | 1 |
| Bucar, F | 1 |
| Gröblacher, B | 1 |
| Brantner, A | 1 |
| Merino, V | 1 |
| Kalia, Y | 1 |
| Scapozza, L | 1 |
| Perozzo, R | 1 |
| Weis, R | 1 |
| Lee, SC | 1 |
| Hong, TH | 1 |
| Kim, OH | 1 |
| Cho, SJ | 1 |
| Kim, KH | 1 |
| Song, JS | 1 |
| Hwang, KS | 1 |
| Jung, JK | 1 |
| Hong, HE | 1 |
| Seo, H | 1 |
| Choi, HJ | 1 |
| Ahn, J | 1 |
| Lee, TY | 1 |
| Rim, E | 1 |
| Jung, KY | 1 |
| Kim, SJ | 1 |
| Olsen, RJ | 1 |
| Zhu, L | 1 |
| Musser, JM | 1 |
| Seker, FB | 1 |
| Kilic, U | 1 |
| Caglayan, B | 1 |
| Ethemoglu, MS | 1 |
| Caglayan, AB | 1 |
| Ekimci, N | 1 |
| Demirci, S | 1 |
| Dogan, A | 1 |
| Oztezcan, S | 1 |
| Sahin, F | 1 |
| Yilmaz, B | 1 |
| Kilic, E | 1 |
| Tokiwa, T | 2 |
| Zimin, L | 1 |
| Ishizuka, S | 2 |
| Inoue, T | 3 |
| Fujii, M | 3 |
| Ishiguro, H | 1 |
| Kajigaya, H | 1 |
| Owada, Y | 2 |
| Suzuki, M | 3 |
| Yamakawa, T | 4 |
| Le, CF | 1 |
| Yusof, MY | 1 |
| Hassan, MA | 1 |
| Lee, VS | 1 |
| Isa, DM | 1 |
| Sekaran, SD | 1 |
| Sawada, A | 1 |
| Fujiwara, Y | 1 |
| Nagami, Y | 1 |
| Tanaka, F | 1 |
| Yamagami, H | 1 |
| Tanigawa, T | 1 |
| Shiba, M | 1 |
| Tominaga, K | 1 |
| Watanabe, T | 1 |
| Gi, M | 1 |
| Wanibuchi, H | 1 |
| Arakawa, T | 1 |
| Osharina, V | 1 |
| Aarabi, A | 1 |
| Manoochehri, M | 1 |
| Mahmoudzadeh, M | 1 |
| Wallois, F | 1 |
| Salado, IR | 1 |
| García, AP | 1 |
| Aguilar, MA | 1 |
| Calvo, JM | 1 |
| Akdogan, I | 1 |
| Adiguzel, E | 1 |
| Yilmaz, I | 1 |
| Ozdemir, MB | 1 |
| Sahiner, M | 1 |
| Tufan, AC | 1 |
| Lau, DH | 1 |
| Clausen, C | 1 |
| Sosunov, EA | 1 |
| Shlapakova, IN | 1 |
| Anyukhovsky, EP | 1 |
| Danilo, P | 1 |
| Rosen, TS | 1 |
| Kelly, C | 1 |
| Duffy, HS | 1 |
| Szabolcs, MJ | 1 |
| Chen, M | 1 |
| Robinson, RB | 1 |
| Lu, J | 1 |
| Kumari, S | 1 |
| Cohen, IS | 1 |
| Rosen, MR | 1 |
| Caso, JR | 1 |
| Hurtado, O | 1 |
| Pereira, MP | 1 |
| García-Bueno, B | 1 |
| Menchén, L | 1 |
| Alou, L | 1 |
| Gómez-Lus, ML | 1 |
| Moro, MA | 1 |
| Lizasoain, I | 1 |
| Leza, JC | 1 |
| Rodikov, MV | 1 |
| Rudnev, VA | 1 |
| Besio, WG | 1 |
| Gale, KN | 1 |
| Medvedev, AV | 1 |
| Akman, T | 1 |
| Erken, H | 1 |
| Acar, G | 1 |
| Bolat, E | 1 |
| Kizilay, Z | 1 |
| Acar, F | 1 |
| Genc, O | 1 |
| Fukami, M | 1 |
| Tanka, A | 1 |
| Takikawa, H | 1 |
| Nomura, S | 2 |
| Maruta, Y | 2 |
| He, Y | 2 |
| Koizumi, H | 1 |
| Shirao, S | 1 |
| Kunitsugu, I | 1 |
| Kida, H | 1 |
| Taniguchi, K | 1 |
| Ichikawa, T | 1 |
| Saito, T | 1 |
| Uyanikgil, Y | 1 |
| Baka, M | 1 |
| Yurtseven, M | 1 |
| Turgut, M | 1 |
| Mameli, O | 1 |
| Caria, MA | 1 |
| Pintus, A | 1 |
| Padua, G | 1 |
| Mameli, S | 1 |
| Tong, TC | 1 |
| Hernandez, M | 1 |
| Richardson, WH | 1 |
| Betten, DP | 1 |
| Favata, M | 1 |
| Riffenburgh, RH | 1 |
| Clark, RF | 1 |
| Tanen, DA | 1 |
| Powers, TE | 2 |
| Varma, KJ | 2 |
| Powers, JD | 2 |
| Gabel, AA | 1 |
| Spurlock, SL | 1 |
| Haglund, MM | 1 |
| Schwartzkroin, PA | 2 |
| Young, EJ | 1 |
| Weingarten, NM | 1 |
| Baughn, RE | 1 |
| Duncan, WC | 1 |
| Holm, SE | 1 |
| Thadepalli, H | 1 |
| Mandal, AK | 1 |
| Rambhatla, K | 1 |
| Bach, VT | 1 |
| Lounsbery, JL | 1 |
| Green, LR | 1 |
| Furtado, D | 1 |
| Kostopoulos, G | 1 |
| Gloor, P | 3 |
| Pellegrini, A | 1 |
| Siatitsas, I | 1 |
| Lombardini, JB | 1 |
| Frigyesi, TL | 1 |
| Johnston, D | 1 |
| Brown, TH | 1 |
| Tateda, K | 2 |
| Takashima, K | 1 |
| Miyazaki, H | 1 |
| Matsumoto, T | 2 |
| Hatori, T | 1 |
| Yamaguchi, K | 2 |
| Cross, SE | 1 |
| Thompson, MJ | 1 |
| Roberts, MS | 1 |
| Knudsen, JD | 1 |
| Frimodt-Møller, N | 1 |
| Espersen, F | 1 |
| Murakami, K | 1 |
| Miyazaki, S | 1 |
| Fisher, RS | 2 |
| Prince, DA | 4 |
| Quesney, LF | 1 |
| Kratzenberg, E | 1 |
| Zumstein, H | 1 |
| Hochner, B | 1 |
| Spira, ME | 1 |
| Werman, R | 1 |
| Tanganelli, P | 1 |
| Benassi, E | 1 |
| Besio, G | 1 |
| Ottonello, GA | 1 |
| Primavera, A | 1 |
| Roberts, TL | 1 |
| Futrell, JW | 1 |
| Sande, MA | 1 |
| Gardiner, TH | 1 |
| McAnalley, BH | 1 |
| Heaton, J | 1 |
| Reynolds, RC | 1 |
| Oliver, AP | 1 |
| Hoffer, BJ | 1 |
| Wyatt, RJ | 1 |
| Hanson, DG | 1 |
| Juhn, SK | 1 |
| Giebink, GS | 1 |
| Paparella, MM | 1 |
| Dickerman, JD | 1 |
| Bolton, E | 1 |
| Coil, JA | 1 |
| Chalmer, BJ | 1 |
| Jakab, GJ | 1 |
| MacGregor, RR | 1 |
| Walker, CB | 1 |
| Nitzan, D | 1 |
| Wilkins, TD | 1 |
| Courtney, KR | 1 |
| Carey, RB | 1 |
| Brause, BD | 1 |
| Roberts, RB | 1 |
| Collins, RC | 2 |
| Gloor, BP | 1 |
| Rokos, L | 1 |
| Leuenberger, R | 1 |
| Myers, RR | 1 |
| Burchiel, KJ | 1 |
| Stockard, JJ | 1 |
| Bickford, RG | 1 |
| Pelletier, LL | 1 |
| Durack, DT | 1 |
| Petersdorf, RG | 1 |
| Hablitz, JJ | 1 |
| Chudwin, DS | 1 |
| Tanaka, S | 1 |
| Kaijima, M | 1 |
| Tanaka, T | 1 |
| Kunimoto, M | 1 |
| Yonemasu, Y | 1 |
| Jung, TT | 1 |
| Traub, WH | 1 |
| Nurusheva, SM | 1 |
| Shcherbakova, NI | 1 |
| Lebedeva, MV | 1 |
| Peterson, LR | 1 |
| Moody, JA | 1 |
| Fasching, CE | 1 |
| Gerding, DN | 1 |
| Dewar, HA | 1 |
| Jones, MR | 1 |
| Barnes, WS | 1 |
| Griffin, SG | 1 |
| Videen, TO | 1 |
| Daw, NW | 1 |
| Badenoch, PR | 1 |
| Hay, GJ | 1 |
| McDonald, PJ | 1 |
| Coster, DJ | 1 |
| Dijkmans, BA | 1 |
| Vaishnav, J | 1 |
| Mattie, H | 1 |
| Pulliam, L | 1 |
| Dall, L | 1 |
| Inokuchi, S | 1 |
| Wilson, W | 1 |
| Hadley, WK | 1 |
| Mills, J | 1 |
| Oshima, E | 1 |
| Urabe, N | 1 |
| Shingu, K | 1 |
| Mori, K | 1 |
| Liu, LX | 1 |
| Zhang, XY | 1 |
| Song, HY | 1 |
| Niu, HZ | 1 |
| Li, ZJ | 1 |
| Edmonds, HL | 2 |
| Stark, LG | 2 |
| Testa, G | 1 |
| Müller, HE | 1 |
| Hollinger, MA | 1 |
| Levine, BB | 1 |
| Coppi, G | 1 |
| Bonardi, G | 1 |
| van Duijn, H | 1 |
| Mutani, R | 1 |
| Bergamini, L | 1 |
| Fariello, R | 1 |
| Delsedime, M | 1 |
| Guckian, JC | 1 |
| Makin, M | 1 |
| Geller, R | 1 |
| Jacobs, J | 1 |
| Sacks, T | 1 |
| Pinson, L | 1 |
| Isaacson, RL | 2 |
| Gage, FH | 1 |
| Rosen, AD | 1 |
| Lubowsky, J | 1 |
| Vastola, EF | 1 |
| Rudzit, EA | 1 |
| Lisitsa, LI | 1 |
| Sapico, FL | 1 |
| Kalmanson, GM | 1 |
| Montgomerie, JZ | 1 |
| Hewitt, WL | 1 |
| Guze, LB | 1 |
| Wilson, FC | 1 |
| Worcester, JN | 1 |
| Coleman, PD | 1 |
| Byrd, WE | 1 |
4 reviews available for penicillin g and Disease Models, Animal
| Article | Year |
|---|---|
Possible therapeutic effects of transcutaneous electrical stimulation via concentric ring electrodes.
Topics: Animals; Convulsants; Disease Models, Animal; Electrodes; Penicillin G; Pentylenetetrazole; Pilocarp | 2010 |
Selecting therapeutic concentrations: minimum inhibitory concentrations vs subminimum or supraminimum inhibitory concentrations.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Disease Models, Animal; Dog Diseases | 1984 |
Genetics of atopic allergy and reagin production.
Topics: Adolescent; Adult; Allergens; Animals; Antibody Formation; Asthma; Binding Sites, Antibody; Cattle; | 1973 |
[Experimental pyelonephritis, chemotherapeutic studies (review of the literature)].
Topics: Acute Disease; Ampicillin; Animals; Anti-Bacterial Agents; Chloramphenicol; Chronic Disease; Coryneb | 1971 |
1 trial available for penicillin g and Disease Models, Animal
| Article | Year |
|---|---|
Fibrinolytic therapy in bacterial endocarditis: experimental studies in dogs.
Topics: Animals; Anistreplase; Brain; Clinical Trials as Topic; Disease Models, Animal; Dogs; Endocarditis, | 1986 |
82 other studies available for penicillin g and Disease Models, Animal
| Article | Year |
|---|---|
Biological and mechanistic activities of xanthorrizol and 4-(1',5'-dimethylhex-4'-enyl)-2-methylphenol isolated from Iostephane heterophylla.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Asteraceae; Candida albica | 2001 |
Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Estrone; Ma | 2004 |
Efficacy of oritavancin in a murine model of Bacillus anthracis spore inhalation anthrax.
Topics: Administration, Inhalation; Animals; Anthrax; Anti-Bacterial Agents; Bacillus anthracis; Disease Mod | 2008 |
Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model.
Topics: Animals; Anthrax; Anti-Bacterial Agents; Bacillus anthracis; beta-Lactamases; beta-Lactams; Blood Pr | 2010 |
Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Azabicyclo Compounds; Disease Models, Animal; D | 2015 |
A Novel Way of Preventing Postoperative Pancreatic Fistula by Directly Injecting Profibrogenic Materials into the Pancreatic Parenchyma.
Topics: Animals; Anti-Bacterial Agents; Benzamides; Digestive System Surgical Procedures; Dioxoles; Disease | 2020 |
A Single Amino Acid Replacement in Penicillin-Binding Protein 2X in Streptococcus pyogenes Significantly Increases Fitness on Subtherapeutic Benzylpenicillin Treatment in a Mouse Model of Necrotizing Myositis.
Topics: Amino Acid Substitution; Animals; Anti-Bacterial Agents; Disease Models, Animal; Fasciitis, Necrotiz | 2020 |
HMG-CoA reductase inhibitor rosuvastatin improves abnormal brain electrical activity via mechanisms involving eNOS.
Topics: Animals; Anticonvulsants; Atorvastatin; bcl-2-Associated X Protein; Blood-Brain Barrier; Brain; Capi | 2015 |
The Palm-Sized Cryoprobe System Based on Refrigerant Expansion and Boiling and Its Application to an Animal Model of Epilepsy.
Topics: Animals; Brain; Cryotherapy; Disease Models, Animal; Epilepsy; Equipment Design; Necrosis; Penicilli | 2015 |
In vivo efficacy and molecular docking of designed peptide that exhibits potent antipneumococcal activity and synergises in combination with penicillin.
Topics: Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacterial Proteins; Binding Sites; | 2015 |
Alteration of Esophageal Microbiome by Antibiotic Treatment Does Not Affect Incidence of Rat Esophageal Adenocarcinoma.
Topics: Adenocarcinoma; Ampicillin; Anastomosis, Surgical; Animals; Anti-Bacterial Agents; Barrett Esophagus | 2016 |
Hemodynamic Changes Associated with Interictal Spikes Induced by Acute Models of Focal Epilepsy in Rats: A Simultaneous Electrocorticography and Near-Infrared Spectroscopy Study.
Topics: Animals; Bicuculline; Brain; Disease Models, Animal; Electrocorticography; Electroencephalography; E | 2017 |
Inhibitory effect of state independent ponto-geniculo-occipital waves on seizure occurrence induced by local application of penicillin into the temporal lobe amygdala.
Topics: Amygdala; Analgesics, Non-Narcotic; Animals; Brain Mapping; Carbachol; Cats; Disease Models, Animal; | 2008 |
Penicillin-induced epilepsy model in rats: dose-dependant effect on hippocampal volume and neuron number.
Topics: Animals; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalograph | 2008 |
Epicardial border zone overexpression of skeletal muscle sodium channel SkM1 normalizes activation, preserves conduction, and suppresses ventricular arrhythmia: an in silico, in vivo, in vitro study.
Topics: Action Potentials; Adenoviridae; Animals; Cell Line; Computer Simulation; Disease Models, Animal; Do | 2009 |
Colonic bacterial translocation as a possible factor in stress-worsening experimental stroke outcome.
Topics: Animals; Anti-Bacterial Agents; Bacterial Translocation; Colitis; Colon; Corticosterone; Cyclooxygen | 2009 |
[Concentration of benzylpenicillin sodium salt in the cerebrospinal fluid of patients with late neurosyphilis as an indicator of efficacy of specific therapy].
Topics: Adult; Aged; Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Chromatography, High Pressure Liqu | 2009 |
Effects of the hippocampal deep brain stimulation on cortical epileptic discharges in penicillin - induced epilepsy model in rats.
Topics: Animals; Cerebral Cortex; Deep Brain Stimulation; Disease Models, Animal; Electrodes, Implanted; Ele | 2011 |
Effect of penicillin G on the biliary excretion of cholephilic compounds in rats.
Topics: Animals; Anti-Bacterial Agents; Bile; Bile Acids and Salts; Body Fluids; Disease Models, Animal; Mal | 2011 |
Cooling of the epileptic focus suppresses seizures with minimal influence on neurologic functions.
Topics: Animals; Body Temperature; Brain Waves; Cobalt; Convulsants; Disease Models, Animal; Electronics, Me | 2012 |
Focal brain cooling terminates the faster frequency components of epileptic discharges induced by penicillin G in anesthetized rats.
Topics: Anesthetics; Animals; Anti-Bacterial Agents; Brain; Brain Waves; Disease Models, Animal; Electroence | 2012 |
The effect of experimental epilepsy induced by penicillin administration during pregnancy on nestin expression in the immature rat cerebellum. A light, electron microscopic, and immunohistochemical study.
Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Movement; Cell Nucleus; Cerebellum; Convulsant | 2004 |
Sudden death in epilepsy: an experimental animal model.
Topics: Animals; Arrhythmias, Cardiac; Death, Sudden; Disease Models, Animal; Electrocardiography; Electroen | 2006 |
Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model.
Topics: Acetylcysteine; Alanine Transaminase; Amanitins; Animals; Antidotes; Aspartate Aminotransferases; Ch | 2007 |
A health index to evaluate clinically a beta-hemolytic streptococcal infectious disease model in the horse.
Topics: Animals; Disease Models, Animal; Horse Diseases; Horses; Microbial Sensitivity Tests; Penicillin G; | 1984 |
Seizure-like spreading depression in immature rabbit hippocampus in vitro.
Topics: Animals; Bicuculline; Disease Models, Animal; Electrophysiology; Epilepsy; Hippocampus; In Vitro Tec | 1984 |
Studies on the pathogenesis of the Jarisch-Herxheimer reaction: development of an animal model and evidence against a role for classical endotoxin.
Topics: Adult; Animals; Antigen-Antibody Complex; Biopsy; Complement Activating Enzymes; Complement C1q; Dis | 1982 |
Comparative efficacy of cefadroxil and penicillin versus beta-streptococcal infection in an experimental in-vivo model.
Topics: Animals; Cefadroxil; Cephalexin; Disease Models, Animal; Injections, Intramuscular; Penicillin G; Ra | 1982 |
Is penicillin alone effective in enterococcal endocarditis? An experimental study in rabbits.
Topics: Animals; Disease Models, Animal; Endocarditis, Bacterial; Enterococcus faecalis; Male; Penicillin G; | 1981 |
Type III group B streptococcal infections in mice: bacteremia and meningitis following oral inoculation.
Topics: Animals; Disease Models, Animal; Meningitis; Mice; Mouth Mucosa; Penicillin G; Sepsis; Streptococcal | 1981 |
A study of the transition from spindles to spike and wave discharge in feline generalized penicillin epilepsy: EEG features.
Topics: Animals; Brain; Cats; Disease Models, Animal; Electroencephalography; Penicillin G; Seizures | 1981 |
Taurine-induced thalamocortical dissociative effects in an experimental model of epilepsy.
Topics: Action Potentials; Animals; Brain; Cats; Cerebellum; Cerebral Cortex; Disease Models, Animal; Epilep | 1981 |
Giant synaptic potential hypothesis for epileptiform activity.
Topics: Action Potentials; Animals; Disease Models, Animal; Electric Conductivity; Epilepsy; Guinea Pigs; Hi | 1981 |
Noncompromised penicillin-resistant pneumococcal pneumonia CBA/J mouse model and comparative efficacies of antibiotics in this model.
Topics: Animals; Anti-Bacterial Agents; Cefotaxime; Disease Models, Animal; Imipenem; Lung; Male; Mice; Mice | 1996 |
Distribution of systemically administered ampicillin, benzylpenicillin, and flucloxacillin in excisional wounds in diabetic and normal rats and effects of local topical vasodilator treatment.
Topics: Acetylcholine; Administration, Topical; Ampicillin; Animals; Chromatography, High Pressure Liquid; D | 1996 |
Pharmacodynamics of penicillin are unaffected by bacterial growth phases of Streptococcus pneumoniae in the mouse peritonitis model.
Topics: Animals; Ascitic Fluid; Colony Count, Microbial; Disease Models, Animal; Dose-Response Relationship, | 1998 |
Efficacy of a novel tetracycline derivative, glycylcycline, against penicillin-resistant Streptococcus pneumoniae in a mouse model of pneumonia.
Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Female; Lung; Mice; Mice, Inbred CBA; Microb | 2000 |
Spike-wave rhythms in cat cortex induced by parenteral penicillin. I. Electroencephalographic features.
Topics: Animals; Barbiturates; Cats; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Haloth | 1977 |
Spike-wave rhythms in cat cortex induced by parenteral penicillin. II. Cellular features.
Topics: Action Potentials; Animals; Cats; Cerebral Cortex; Disease Models, Animal; Electroencephalography; M | 1977 |
Pathophysiology of generalized penicillin epilepsy in the cat: the role of cortical and subcortical structures. I. Systemic application of penicillin.
Topics: Animals; Brain; Cats; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Gyrus Cinguli | 1977 |
Penicillin decreases chloride conductance in crustacean muscle: a model for the epileptic neuron.
Topics: Animals; Brachyura; Cell Membrane; Chlorides; Disease Models, Animal; Dose-Response Relationship, Dr | 1976 |
[Parenteral penicillin in rats: an experimental model of periodic EEG activity].
Topics: Animals; Brain; Disease Models, Animal; Electroencephalography; Injections, Intraperitoneal; Myoclon | 1979 |
Antibiotic penetration into normal and inflamed tissues as reflected by peripheral lymph.
Topics: Animals; Anti-Bacterial Agents; Blood Proteins; Catheterization; Cefazolin; Cellulitis; Disease Mode | 1979 |
Changes in the pulmonary uptake and binding of drugs in an experimental model of lung fibrosis.
Topics: Animals; Dexamethasone; Disease Models, Animal; Isoniazid; Lung; Male; Paraquat; Penicillin G; Pulmo | 1979 |
The hippocampal slice: a system for studying the pharmacology of seizures and for screening anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroenc | 1977 |
Lactate dehydrogenase as a measure of inflammation in experimental otitis media.
Topics: Animals; Chinchilla; Disease Models, Animal; L-Lactate Dehydrogenase; Otitis Media; Penicillin G; Pn | 1978 |
Protective effect of prophylactic penicillin on splenectomized mice exposed to an aerosolized suspension of type III Streptococcus pneumoniae.
Topics: Aerosols; Animals; Disease Models, Animal; Lung; Male; Mice; Penicillin G; Pneumococcal Infections; | 1979 |
Comparative penetration of amikacin, gentamicin, and penicillin g into exudate fluid in experimental sterile peritonitis.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Ascitic Fluid; Disease Models, Animal; Gentamicins; Inject | 1977 |
Chemotherapy of an experimental Bacteroides fragilis infection in mice.
Topics: Abscess; Animals; Bacteroides fragilis; Bacteroides Infections; Cephalothin; Chloramphenicol; Clinda | 1977 |
Epileptogenesis in neocortical slices.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Evoked Potentials; Guinea Pigs; In Vitro Technique | 1977 |
Antimicrobial therapy of vitamin B6-dependent streptococcal endocarditis.
Topics: Adult; Animals; Disease Models, Animal; Drug Synergism; Endocarditis, Bacterial; Humans; Male; Micro | 1977 |
Metabolic response to focal penicillin seizures in rat: spike discharge vs. afterdischarge.
Topics: Animals; Autoradiography; Cerebral Cortex; Deoxyglucose; Disease Models, Animal; Electroencephalogra | 1976 |
[Transport of 131J-iodo-o-hippurate and 22Na out of the retroretinal space in experimental non rhegmatogenous detachment of the retina (author's transl)].
Topics: Animals; Biological Transport; Cats; Disease Models, Animal; Injections; Iodine Radioisotopes; Iodoh | 1975 |
Effects of acute and chronic paleocerebellar stimulation on experimental models of epilepsy in the cat: studies with enflurane, pentylenetetrazol, penicillin, and chloralose.
Topics: Acoustic Stimulation; Animals; Cats; Cerebellum; Chloralose; Disease Models, Animal; Electric Stimul | 1975 |
Chemotherapy of experimental streptococcal endocarditis. IV. Further observations on prophylaxis.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Cefazolin; Cephalexin; Clindamycin; Disease Models, Anim | 1975 |
Intramuscular penicillin epilepsy in the cat: effects of chronic cerebellar stimulation.
Topics: Action Potentials; Animals; Cats; Cerebellum; Disease Models, Animal; Electric Stimulation; Female; | 1976 |
Prophylaxis and treatment of pneumococcal bacteremia by immune globulin intravenous in a mouse model.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Immunologic; Drug Therapy, Combination; | 1989 |
[Acute effect of penicillin G on feline models of focal epilepsy].
Topics: Amygdala; Animals; Cats; Convulsants; Disease Models, Animal; Epilepsies, Partial; Injections, Intra | 1989 |
Prostaglandins, leukotrienes, and other arachidonic acid metabolites in the pathogenesis of otitis media.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Chinchilla; Dinoprostone; Disease Models, | 1988 |
Chemotherapy of experimental (murine) Clostridium perfringens type A gas gangrene.
Topics: Animals; Ciprofloxacin; Clindamycin; Clostridium perfringens; Disease Models, Animal; Gas Gangrene; | 1988 |
[Use of an experimental model of mixed chlamydial-gonococcal infection in ovo for evaluating the etiotropic action of chemopreparations].
Topics: Animals; Chick Embryo; Chlamydia Infections; Chlamydia trachomatis; Disease Models, Animal; Drug Eva | 1986 |
In vivo and in vitro activity of ciprofloxacin plus azlocillin against 12 streptococcal isolates in a neutropenic site model.
Topics: Amikacin; Animals; Azlocillin; Ciprofloxacin; Disease Models, Animal; Drug Synergism; Drug Therapy, | 1987 |
Penicillin-induced epileptiform activity does not prevent ocular dominance shifts in monocularly deprived kittens.
Topics: Animals; Autoradiography; Cats; Disease Models, Animal; Dominance, Cerebral; Electroencephalography; | 1986 |
A rat model of bacterial keratitis. Effect of antibiotics and corticosteroid.
Topics: Animals; Bacterial Infections; Cephalosporins; Cephradine; Disease Models, Animal; Drug Therapy, Com | 1985 |
Efficacy of amoxycillin and benzylpenicillin combined with clavulanic acid against Bacteroides fragilis in vitro and in experimentally infected mice.
Topics: Amoxicillin; Animals; Bacteroides fragilis; Bacteroides Infections; beta-Lactamases; Clavulanic Acid | 1985 |
Effects of exopolysaccharide production by viridans streptococci on penicillin therapy of experimental endocarditis.
Topics: Animals; Disease Models, Animal; Endocarditis; Penicillin G; Penicillin G Procaine; Penicillin Resis | 1985 |
Anticonvulsant actions of enflurane on epilepsy models in cats.
Topics: Amygdala; Animals; Anticonvulsants; Bicuculline; Cats; Disease Models, Animal; Dose-Response Relatio | 1985 |
[Studies on the hamster colitis model].
Topics: Animals; Cricetinae; Disease Models, Animal; Enterocolitis, Pseudomembranous; Female; Gentamicins; M | 1985 |
Technical contribution. A method for the application of substances to the brain while maintaining physiological conditions.
Topics: Animals; Brain; Cerebral Cortex; Disease Models, Animal; Methods; Penicillin G; Seizures; Stereotaxi | 1974 |
Generalized penicillin epilepsy in the cat: effects of intracarotid and intravertebral pentylenetetrazol and amobarbital injections.
Topics: Amobarbital; Animals; Brain Stem; Carotid Arteries; Cats; Cerebral Cortex; Disease Models, Animal; E | 1974 |
[Spontaneous regression of Ehrlich ascites tumour by infection with pneumococci (author's transl)].
Topics: Animals; Carcinoma, Ehrlich Tumor; Disease Models, Animal; Female; Injections, Intraperitoneal; Mice | 1974 |
The effects of diphenylhydantoin, phenobarbital, and diazepam on the penicillin-induced epileptogenic focus in the rat.
Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Diazepam; Disease Models, Animal; Electroence | 1974 |
Urease-inhibiting action of some drugs in vitro and in vivo.
Topics: Ammonia; Animals; Anti-Bacterial Agents; Ascorbic Acid; Bacitracin; Chloramphenicol; Chlortetracycli | 1970 |
Effects of projected cortical epileptiform discharges on field potentials in the cat cuneate nucleus.
Topics: Animals; Cats; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Epilepsy; Evoked Poten | 1974 |
Effects of taurine on cortical acute epileptic foci.
Topics: Animals; Anticonvulsants; Cats; Cerebral Cortex; Cobalt; Disease Models, Animal; Electroencephalogra | 1974 |
Role of metabolism in pathogenesis of bacteremia due to Diplococcus pneumoniae in rabbits.
Topics: Acetates; Adenosine Diphosphate; Adenosine Triphosphate; Amino Acids; Animals; Carbohydrate Metaboli | 1973 |
Non-toxic detergent irrigation of chronic infections. An experimental evaluation.
Topics: Animals; Chronic Disease; Detergents; Disease Models, Animal; Osteomyelitis; Penicillin G; Penicilli | 1973 |
Propagation of epileptiform activity in the brain examined by frequency-wavenumber analysis.
Topics: Action Potentials; Animals; Brain; Cerebral Cortex; Disease Models, Animal; Electroencephalography; | 1973 |
Hypothalamic stimulation and the persistence of epileptiform discharges.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epil | 1973 |
Geniculate interactions with a penicillin discharge in visual cortex.
Topics: Animals; Cats; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy; Evoke | 1973 |
Pyelonephritis. XII. Comparison of penicillin, ampicillin, and streptomycin in enterococcal infection in rats.
Topics: Ampicillin; Animals; Bacteriological Techniques; Disease Models, Animal; Enterococcus faecalis; Inje | 1971 |
Antibiotic penetration of experimental bone hematomas.
Topics: Animals; Bone and Bones; Disease Models, Animal; Dogs; Hematoma; Injections, Intravenous; Penicillin | 1971 |