Page last updated: 2024-11-07

penicillin g and Dermatitis Medicamentosa

penicillin g has been researched along with Dermatitis Medicamentosa in 50 studies

Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.

Research Excerpts

ExcerptRelevanceReference
"Of the currently recommended regimens for treatment of uncomplicated gonorrhea, only aqueous penicillin G procaine is effective against infections at all sites."9.05Comparative study of ceftriaxone and spectinomycin for treatment of pharyngeal and anorectal gonorrhea. ( Ehret, JM; Handsfield, HH; Judson, FN, 1985)
"Of the currently recommended regimens for treatment of uncomplicated gonorrhea, only aqueous penicillin G procaine is effective against infections at all sites."5.05Comparative study of ceftriaxone and spectinomycin for treatment of pharyngeal and anorectal gonorrhea. ( Ehret, JM; Handsfield, HH; Judson, FN, 1985)
"A patient with bullae and target lesions on the extremities and mucous membranes was seen with the clinical picture of erythema multiforme following an episode of pneumonia and a course of penicillin G potassium and tobramycin sulfate therapy."3.66Possible drug-induced pemphigus-like antibodies with the clinical manifestation of erythema multiforme. ( Ansel, J; Kumar, V; Petrozzi, JW, 1983)
"The patient was subsequently treated for syphilis with ocular involvement with a course of intravenous benzylpenicillin, resulting in rapid symptomatic improvement."1.51Secondary syphilis presenting with acute unilateral vision loss and a widespread maculopapular rash. ( Kumar, K; Russell, GK; Trevelyan, G; Wickremasinghe, M, 2019)
" Patients can then be advised to undergo a tolerance test with safe penicillins instead of provocation with culprit penicillins for confirmation of penicillin allergy."1.32Combined in vivo and in vitro approach for the characterization of penicillin-specific polyclonal lymphocyte reactivity: tolerance tests with safe penicillins instead of challenge with culprit drugs. ( Al Masaoudi, T; Erdmann, S; Merk, HF; Sachs, B, 2004)
"Whereas haemolytic anaemia (7) and neutropenia (12) were observed in 19 cases of the first group no such reactions were seen in the second group."1.27Adverse reactions following intravenous penicillin-G relate to degradation of the drug in vitro. ( Gubler, J; Neftel, KA; Schulthess, HK; Wälti, M, 1984)
"Forty patients having fixed drug eruptions were subjected to provocation tests."1.26Drugs causing fixed eruptions. ( Pasricha, JS, 1979)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199035 (70.00)18.7374
1990's8 (16.00)18.2507
2000's4 (8.00)29.6817
2010's3 (6.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Trevelyan, G1
Kumar, K1
Russell, GK1
Wickremasinghe, M1
Blackmur, JP1
Lammy, S1
Baring, DE1
Wessbecher, R1
Stangl, S1
Ezzouine, H1
Charra, B1
Benslama, A1
Motaouakkil, S1
Sachs, B1
Al Masaoudi, T1
Merk, HF1
Erdmann, S1
Spanou, Z1
Keller, M1
Britschgi, M1
Yawalkar, N1
Fehr, T1
Neuweiler, J1
Gugger, M1
Mohaupt, M1
Pichler, WJ2
Geffriaud, T1
Brunet, AS1
Ktiouet, S1
Chambost, V1
Rozières, A1
Bérard, F1
Nicolas, JF2
Gunera-Saad, N1
Ikezawa, Z3
Kitamura, K2
Murakami, J1
Nagai, R3
Iwata, M1
Ansel, J1
Petrozzi, JW1
Kumar, V1
Neftel, KA1
Wälti, M1
Schulthess, HK1
Gubler, J1
Haustein, UF1
Romano, A1
Di Fonso, M1
Papa, G1
Pietrantonio, F1
Federico, F1
Fabrizi, G1
Venuti, A1
Vega, JM1
Blanca, M1
García, JJ1
Carmona, MJ1
Miranda, A1
Pérez-Estrada, M1
Fernández, S1
Acebes, JM1
Terrados, S1
Combemale, P1
Gavaud, C1
Cozzani, E1
Guennoc, B1
Dusseau, JY1
Torricelli, R1
Wüthrich, B1
Schnyder, B1
Helbling, A1
Kappeler, A1
Regele, D1
Ruëff, F1
Degitz, K1
Przybilla, B1
Kovalenko, LP1
Solov'ev, VN1
Lackner, F1
Erlach, E1
Haider, W1
Kraft, D2
Krystof, G1
Pichler, H1
Fitzal, S1
Levin, S1
Neu, HC1
Ponvert, C1
Saurat, JH1
Scheinmann, P1
Galoppin, L1
Paupe, J1
Girard, JP1
Pasricha, JS1
Templeton, WC1
Melo, JC1
Raff, MJ1
Koller, DY1
Rosenkranz, AR1
Pirker, C1
Götz, M1
Jarisch, R1
Shen, K1
Rudzki, E1
Rebandel, P1
Rocklin, RE1
Aihara, M2
de Haan, P1
Bruynzeel, DP1
van Ketel, WG1
Alcalay, J1
David, M1
Ingber, A1
Hazaz, B1
Sandbank, M1
Judson, FN1
Ehret, JM1
Handsfield, HH1
Comaish, S1
Dubileĭ, VV1
Balabaeva, PN1
Strassmann, H1
Pedersen-Bjergaard, J2
Stewart, RH1
Webster, SB1
Gilbert, DN1
Sanford, JP1
Fishman, LS1
Hewitt, WL1
Manios, SG1
Lipiridou, O1
Zaphiriou, J1
Danga, E1
Zervanou, E1
Schulz, KH1
Schöpf, E1
Wex, O1
Jaques, R1
Gelzer, J1
Werner, HP1
Stemberger, H1
Wiedermann, G1
Edwards, DA1
Hahn, AL1
Spitzy, KH1
Davies, RJ1
Hendrick, DJ1
Pepys, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Interest of the Second Phase of the Oral Challenge Test in Patients With Suspected Long-standing Penicillin Allergy[NCT04513938]195 participants (Actual)Observational2020-07-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for penicillin g and Dermatitis Medicamentosa

ArticleYear
Baboon syndrome: an unusual complication arising from antibiotic treatment of tonsillitis and review of the literature.
    BMJ case reports, 2013, Nov-28, Volume: 2013

    Topics: Adult; Anti-Bacterial Agents; Biopsy; Diagnosis, Differential; Drug Eruptions; Humans; Male; Penicil

2013
The penicillins. II. Overview of pharmacology, toxicology, and clinical use.
    New York state journal of medicine, 1977, Volume: 77, Issue:6

    Topics: Administration, Oral; Anaphylaxis; Bacterial Infections; Drug Eruptions; Drug Hypersensitivity; Drug

1977
[Studies of patients with penicillin allergy with a review of literature].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1969, Volume: 20, Issue:1

    Topics: Diagnosis, Differential; Drug Eruptions; Hemagglutination Tests; Humans; Penicillin G; Penicillins;

1969
Methicillin: critical appraisal after a decade of experience.
    The Medical clinics of North America, 1970, Volume: 54, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Bacteria; Chemical Phenomena; Chemistry; Child; Cloxacillin; Drug

1970
The natural penicillins.
    The Medical clinics of North America, 1970, Volume: 54, Issue:5

    Topics: Antigen-Antibody Reactions; Arthritis, Infectious; Binding Sites; Cellulitis; Chemical Phenomena; Ch

1970

Trials

3 trials available for penicillin g and Dermatitis Medicamentosa

ArticleYear
Immediate allergic reactions to amoxicillin.
    Allergy, 1994, Volume: 49, Issue:5

    Topics: Adolescent; Adult; Aged; Amoxicillin; Ampicillin; Anaphylaxis; Angioedema; Cross Reactions; Drug Eru

1994
Comparative study of ceftriaxone and spectinomycin for treatment of pharyngeal and anorectal gonorrhea.
    JAMA, 1985, Mar-08, Volume: 253, Issue:10

    Topics: Adult; Cefotaxime; Ceftriaxone; Clinical Trials as Topic; Drug Eruptions; Female; Gonorrhea; Humans;

1985
Meningococcal meningitis. Comparison of ampicillin and combined sulphadimidine-penicillin G treatment.
    Scandinavian journal of infectious diseases, 1969, Volume: 1, Issue:2

    Topics: Administration, Oral; Adolescent; Ampicillin; Child; Child, Preschool; Drug Eruptions; Female; Hemat

1969

Other Studies

42 other studies available for penicillin g and Dermatitis Medicamentosa

ArticleYear
Secondary syphilis presenting with acute unilateral vision loss and a widespread maculopapular rash.
    BMJ case reports, 2019, Sep-18, Volume: 12, Issue:9

    Topics: Anti-Bacterial Agents; Blindness; Diagnosis, Differential; Drug Eruptions; Humans; Male; Middle Aged

2019
Management of tolerance induction in patients with suspected penicillin allergy--a case study.
    International journal of dermatology, 2009, Volume: 48, Issue:5

    Topics: Administration, Oral; Anti-Bacterial Agents; Desensitization, Immunologic; Dose-Response Relationshi

2009
[Respiratory distress revealed a DRESS syndrome].
    Annales francaises d'anesthesie et de reanimation, 2011, Volume: 30, Issue:11

    Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents; Baclofen; Drug Erup

2011
Combined in vivo and in vitro approach for the characterization of penicillin-specific polyclonal lymphocyte reactivity: tolerance tests with safe penicillins instead of challenge with culprit drugs.
    The British journal of dermatology, 2004, Volume: 151, Issue:4

    Topics: Ampicillin; Cells, Cultured; Cephalosporins; Cross Reactions; Drug Eruptions; Drug Tolerance; Humans

2004
Involvement of drug-specific T cells in acute drug-induced interstitial nephritis.
    Journal of the American Society of Nephrology : JASN, 2006, Volume: 17, Issue:10

    Topics: Aged; Anti-Bacterial Agents; Cytokines; Disulfiram; Drug Eruptions; Enzyme Inhibitors; Floxacillin;

2006
[Unexpected immediate allergy to amoxicillin].
    Annales de dermatologie et de venereologie, 2007, Volume: 134, Issue:11

    Topics: Amoxicillin; Anti-Bacterial Agents; Drug Eruptions; Humans; Hypersensitivity, Immediate; Intradermal

2007
Penicillin and cephalosporin--induced rash in guinea pigs.
    The Journal of dermatology, 1982, Volume: 9, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Drug Eruptions; Guinea Pigs; Hypersensitivity, Delay

1982
Possible drug-induced pemphigus-like antibodies with the clinical manifestation of erythema multiforme.
    Archives of dermatology, 1983, Volume: 119, Issue:12

    Topics: Antibodies; Drug Eruptions; Erythema Multiforme; Fluorescent Antibody Technique; Humans; Lymphoma, L

1983
Adverse reactions following intravenous penicillin-G relate to degradation of the drug in vitro.
    Klinische Wochenschrift, 1984, Jan-02, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Drug Compounding; Drug Eruptions; Eosinophilia; Female;

1984
[Fixed drug eruption of different location due to three drugs in one patient (author's transl)].
    Dermatologische Monatschrift, 1980, Volume: 166, Issue:10

    Topics: Adult; Aminopyrine; Barbital; Drug Eruptions; Exanthema; Female; Humans; Penicillin G; Sulfamerazine

1980
Evaluation of adverse cutaneous reactions to aminopenicillins with emphasis on those manifested by maculopapular rashes.
    Allergy, 1995, Volume: 50, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Ampicillin; Benzeneacetamides; Drug Eruptio

1995
[Linear IgA dermatosis induced by penicillin G].
    Annales de dermatologie et de venereologie, 1993, Volume: 120, Issue:11

    Topics: Adult; Drug Eruptions; Fluorescent Antibody Technique; Humans; Immunoglobulin A; Male; Penicillin G;

1993
[Diagnostic procedures in suspected immediate type allergy to penicillins].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1996, Volume: 47, Issue:5

    Topics: Ampicillin; Cephalosporins; Cross Reactions; Drug Eruptions; Drug Hypersensitivity; Humans; Hypersen

1996
Drug-induced papulovesicular exanthema.
    Allergy, 1998, Volume: 53, Issue:8

    Topics: Aged; Amoxicillin; Dermatitis, Allergic Contact; Drug Eruptions; Exanthema; Female; Humans; Immunogl

1998
[Induction of penicillin tolerance in therapy of neurosyphilis in penicillin allergy].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1999, Volume: 50, Issue:3

    Topics: Aged; Anti-Allergic Agents; Desensitization, Immunologic; Drug Eruptions; Drug Therapy, Combination;

1999
[Allergic complications in treatment with beta-lactam antibiotics].
    Antibiotiki, 1979, Volume: 24, Issue:2

    Topics: Adult; Anaphylaxis; Animals; Anti-Bacterial Agents; Antibody Formation; Antigens; beta-Lactams; Ceph

1979
[Evaluation of exanthemas following high-dosage intravenous penicillin combinations in intensive care].
    International journal of clinical pharmacology and biopharmacy, 1976, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Complement C3; Critical Care; Cyclacillin; Drug Eruptions; Female; H

1976
Penicillin sensitivity tests.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Jan-08, Volume: 51, Issue:2

    Topics: Child, Preschool; Drug Eruptions; Female; Humans; Male; Penicillin G; Skin Tests

1977
Leukocyte migration test and penicillin. A study based on 197 tests in subjects with and without skin symptoms of hypersensitivity to penicillin.
    Clinical and experimental dermatology, 1977, Volume: 2, Issue:4

    Topics: Adult; Aged; Cell Migration Inhibition; Drug Eruptions; Female; Humans; Male; Middle Aged; Penicilli

1977
Recurrent angioneurotic oedema and contact dermatitis due to penicillin.
    Contact dermatitis, 1978, Volume: 4, Issue:5

    Topics: Angioedema; Dermatitis, Contact; Drug Eruptions; Female; Humans; Immunity, Cellular; Leg Ulcer; Midd

1978
Drugs causing fixed eruptions.
    The British journal of dermatology, 1979, Volume: 100, Issue:2

    Topics: Antipyrine; Caffeine; Cross Reactions; Drug Combinations; Drug Eruptions; Humans; Penicillin G; Phen

1979
A clinical approach to the choice of antimicrobial agents, Case number 12: Fever and a cutaneous eruption.
    The Journal of the Kentucky Medical Association, 1979, Volume: 77, Issue:12

    Topics: Adult; Anti-Bacterial Agents; Drug Eruptions; Fever; Humans; Male; Penicillin G; Penicillin G Benzat

1979
Assessment of histamine release from basophils in whole blood by benzylpenicilloyl poly-L-lysine in penicillin-sensitized patients.
    Allergy, 1992, Volume: 47, Issue:5

    Topics: Adolescent; Adult; Aged; Basophils; Benzeneacetamides; Drug Eruptions; Histamine Release; Humans; Im

1992
Erythematous reactions at intramuscular injection sites.
    Lancet (London, England), 1990, Sep-15, Volume: 336, Issue:8716

    Topics: Adolescent; Adult; Aged; Child; Dermatitis, Contact; Drug Eruptions; Female; Humans; Injections, Int

1990
Occupational contact urticaria from penicillin.
    Contact dermatitis, 1985, Volume: 13, Issue:3

    Topics: Anaphylaxis; Dermatitis, Contact; Dermatitis, Occupational; Drug Eruptions; Drug Hypersensitivity; F

1985
Penicillin reactions. Desensitize or discontinue?
    Hospital practice (Office ed.), 1986, Jan-30, Volume: 21, Issue:1A

    Topics: Aged; Anaphylaxis; Desensitization, Immunologic; Drug Eruptions; Drug Hypersensitivity; Humans; Male

1986
Drug-induced lymphocyte proliferation in the experimental sulbenicillin (SBPC) rash of guinea pigs and the enhancement effects of interleukin 2 (IL2).
    The Journal of dermatology, 1985, Volume: 12, Issue:4

    Topics: Animals; Drug Eruptions; Guinea Pigs; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Mal

1985
Onset of penicillin rashes: relation between type of penicillin administered and type of immune reactivity.
    Allergy, 1986, Volume: 41, Issue:1

    Topics: Amoxicillin; Ampicillin; Drug Eruptions; Enzyme-Linked Immunosorbent Assay; Humans; Hypersensitivity

1986
Bullous pemphigoid mimicking bullous erythema multiforme: an untoward side effect of penicillins.
    Journal of the American Academy of Dermatology, 1988, Volume: 18, Issue:2 Pt 1

    Topics: Adolescent; Adult; Amoxicillin; Diagnosis, Differential; Drug Eruptions; Erythema Multiforme; Female

1988
[Lymphocyte proliferation test of experimental sulbenicillin rash].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1985, Volume: 95, Issue:6

    Topics: Animals; Cells, Cultured; Drug Eruptions; Guinea Pigs; Lymphocyte Activation; Male; Penicillin G; Su

1985
The blood platelets in immune hypersensitivity.
    Acta dermato-venereologica, 1968, Volume: 48, Issue:6

    Topics: Animals; Antigen-Antibody Reactions; Bacitracin; Blood Platelets; Chloramphenicol; Drug Eruptions; D

1968
[On the side effects in antibiotic therapy].
    Antibiotiki, 1968, Volume: 13, Issue:9

    Topics: Adult; Aged; Anaphylaxis; Angioedema; Anti-Bacterial Agents; Bronchitis; Chloramphenicol; Chronic Di

1968
Possible advantages of highly purified penicillin in avoiding penicilloyl-specific sensitization and allergic reactions.
    Acta allergologica, 1969, Volume: 24, Issue:4

    Topics: Adult; Antigens; Drug Eruptions; Drug Hypersensitivity; Humans; Injections, Intravenous; Passive Cut

1969
Specific hyposensitization of patients with penicillin allergy.
    Acta allergologica, 1969, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Agglutination Tests; Desensitization, Immunologic; Drug Eruptions; Drug Hypersens

1969
Cross reactivity between ampicillin and penicillin G.
    JAMA, 1970, Jul-06, Volume: 213, Issue:1

    Topics: Ampicillin; Drug Eruptions; Female; Humans; Middle Aged; Penicillin G

1970
[Allergic occupational eczemas caused by ampicillin].
    Berufs-Dermatosen, 1970, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Ampicillin; Dermatitis, Occupational; Dicloxacillin; Drug Eruptions; Drug Hyperse

1970
Skin reactions to ampicillin.
    British medical journal, 1972, Feb-19, Volume: 1, Issue:5798

    Topics: Ampicillin; Drug Contamination; Drug Eruptions; Humans; Penicillin G; Proteins

1972
[Experiments in sensitization to ethyl-3,5,6-tri-O-benzyl-D-glucofuranoside (C. 21 401-BA)].
    Schweizerische medizinische Wochenschrift, 1970, Dec-19, Volume: 100, Issue:51

    Topics: Animals; Antigen-Antibody Reactions; Benzyl Compounds; Diphtheria Toxoid; Drug Eruptions; Drug Hyper

1970
[Inhibition of reagin dependent penicilloyl-specific skin reactions in the rabbit through high doses of sodium penicillin G].
    Wiener klinische Wochenschrift, 1972, Oct-20, Volume: 84, Issue:42

    Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Cattle; Drug Eruptions; Humans; Immunologic

1972
Pneumococcal meningitis.
    The Nebraska medical journal, 1973, Volume: 58, Issue:11

    Topics: Adult; Blood-Brain Barrier; Dose-Response Relationship, Drug; Drug Eruptions; Emergencies; Humans; I

1973
[Appearance of exanthema during hing-dosage therapy with beta-lacta antibiotics].
    Acta medica Austriaca, 1974, Volume: 2, Issue:1

    Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactams; Carbenicillin; Cephalosporins; Drug Eruptions; Drug

1974
Asthma due to inhaled chemical agents: ampicillin, benzyl penicillin, 6 amino penicillanic acid and related substances.
    Clinical allergy, 1974, Volume: 4, Issue:3

    Topics: Administration, Intranasal; Administration, Oral; Adult; Ampicillin; Asthma; Beclomethasone; Blood C

1974