Page last updated: 2024-11-07

penicillin g and Cystic Fibrosis

penicillin g has been researched along with Cystic Fibrosis in 7 studies

Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
"A case of ticarcillin-induced hemorrhagic cystitis is presented, and the literature on drug-induced hemorrhagic cystitis is reviewed."3.67Drug-induced hemorrhagic cystitis. ( Relling, MV; Schunk, JE, 1986)
"The emergence of beta-lactam-resistant strains of Pseudomonas aeruginosa in a cystic fibrosis patient treated with high-dose tobramycin and piperacillin was studied."3.66beta-Lactam-resistant Pseudomonas aeruginosa with modified penicillin-binding proteins emerging during cystic fibrosis treatment. ( Bryan, LE; Godfrey, AJ; Rabin, HR, 1981)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moss, RB1
Babin, S1
Hsu, YP1
Blessing-Moore, J1
Lewiston, NJ1
Godfrey, AJ1
Bryan, LE1
Rabin, HR1
Cade, A1
Denton, M1
Brownlee, KG1
Todd, N1
Conway, SP1
Bins, JW1
Mattie, H1
Relling, MV1
Schunk, JE1
Eftimiadi, C1
De Leo, C1
Schito, GC1
Goddard, RF1
Mercer, TT1
O'Neill, PX1
Flores, RL1
Sanchez, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Single Arm 48-Week Follow-on Safety Study to the Core Study (A Multicentre, Multinational, Open-Label, Randomised, Parallel Group Clinical Trial of Tobrineb®/Actitob®/Bramitob® (Tobramycin Solution for Nebulisation, 300mg Twice Daily in 4mL Unit Dose Vi[NCT01111383]Phase 3209 participants (Actual)Interventional2009-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for penicillin g and Cystic Fibrosis

ArticleYear
Allergy to semisynthetic penicillins in cystic fibrosis.
    The Journal of pediatrics, 1984, Volume: 104, Issue:3

    Topics: Adolescent; Adult; Benzeneacetamides; Carbenicillin; Child; Cystic Fibrosis; Drug Hypersensitivity;

1984
beta-Lactam-resistant Pseudomonas aeruginosa with modified penicillin-binding proteins emerging during cystic fibrosis treatment.
    Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:5

    Topics: Adolescent; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Carrier Proteins; Cystic Fibros

1981
Acute bronchopulmonary infection due to Streptococcus milleri in a child with cystic fibrosis.
    Archives of disease in childhood, 1999, Volume: 80, Issue:3

    Topics: Acute Disease; Child; Colistin; Cystic Fibrosis; Drug Therapy, Combination; Female; Floxacillin; Hum

1999
The tubular excretion of benzylpenicillin in patients with cystic fibrosis.
    British journal of clinical pharmacology, 1989, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Child; Cystic Fibrosis; Female; Humans; Infusions, Intravenous; Kidney Tubules; M

1989
Drug-induced hemorrhagic cystitis.
    Clinical pharmacy, 1986, Volume: 5, Issue:7

    Topics: Antineoplastic Agents; Child; Cyclophosphamide; Cystic Fibrosis; Cystitis; Hematuria; Humans; Male;

1986
Antibacterial activity in vitro of sulbenicillin against mucoid and non-mucoid strains of Pseudomonas aeruginosa.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:4

    Topics: Ampicillin; Carbenicillin; Cefotaxime; Cystic Fibrosis; Humans; Methods; Microbial Sensitivity Tests

1985
Output characteristics and clinical efficacy of ultrasonic nebulizers.
    The Journal of asthma research, 1968, Volume: 5, Issue:4

    Topics: Acetylcysteine; Aerosols; Asthma; Bronchial Diseases; Child; Cortisone; Cystic Fibrosis; Humans; Muc

1968