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penicillin g and Chemical and Drug Induced Liver Injury

penicillin g has been researched along with Chemical and Drug Induced Liver Injury in 10 studies

Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.

Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.

Research Excerpts

ExcerptRelevanceReference
" Amatoxin, a peptide contained in several mushroom species, accounts for the majority of severe mushroom poisonings by binding to RNA polymerase II irreversibly, leading to severe hepatonecrosis."3.74Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model. ( Betten, DP; Clark, RF; Favata, M; Hernandez, M; Richardson, WH; Riffenburgh, RH; Tanen, DA; Tong, TC, 2007)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W2
Warner, DJ1
Chen, H1
Cantin, LD1
Kenna, JG1
Stahl, S1
Walker, CL1
Noeske, T1
Chen, M1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Tong, TC1
Hernandez, M1
Richardson, WH1
Betten, DP1
Favata, M1
Riffenburgh, RH1
Clark, RF1
Tanen, DA1
Schaefer, UW1
Hackenberg, K1
Reinwein, D1
Tamura, T1
Neftel, K1
Keusch, G1
Cottagnoud, P1
Widmer, U1
Hany, M1
Gautschi, K1
Joos, B1
Walt, H1
Juchum, W1
Boyd, EM1
Hottenroth, SM1

Reviews

1 review available for penicillin g and Chemical and Drug Induced Liver Injury

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016

Other Studies

9 other studies available for penicillin g and Chemical and Drug Induced Liver Injury

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model.
    Annals of emergency medicine, 2007, Volume: 50, Issue:3

    Topics: Acetylcysteine; Alanine Transaminase; Amanitins; Animals; Antidotes; Aspartate Aminotransferases; Ch

2007
[Cholestatic hepatitis as unusual allergic reaction in cephalothin-treatment].
    MMW, Munchener medizinische Wochenschrift, 1975, Feb-14, Volume: 117, Issue:7

    Topics: Adult; Cephalothin; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Hypersensitivity; Drug

1975
[Death caused by intravenous anesthetics; thoracic pain caused by synthetic penicillin; and liver diseases induced by Glybuzole sometimes used in combination with clindamycin for the treatment of diabetes by dentists in the form of self medication].
    Nihon Shika Ishikai zasshi, 1976, Volume: 29, Issue:9

    Topics: Anesthesia, Intravenous; Chemical and Drug Induced Liver Injury; Dentistry; Female; Humans; Hypoglyc

1976
[Are cephalosporins more active than penicillin G in poisoning with the deadly Amanita?].
    Schweizerische medizinische Wochenschrift, 1988, Jan-16, Volume: 118, Issue:2

    Topics: Animals; Ceftazidime; Cells, Cultured; Cephalosporins; Chemical and Drug Induced Liver Injury; Chick

1988
[Chloramphenicol panmyelopathy in a child].
    Wiener medizinische Wochenschrift (1946), 1970, Jul-25, Volume: 120, Issue:30

    Topics: Anabolic Agents; Blood Cell Count; Blood Transfusion; Bone Marrow; Bone Marrow Diseases; Bone Marrow

1970
The toxicity of phenacetin at the range of the oral LD50(100 days) in albino rats.
    Toxicology and applied pharmacology, 1968, Volume: 12, Issue:1

    Topics: Animals; Asthenia; Ataxia; Caffeine; Chemical and Drug Induced Liver Injury; Cyanosis; Dehydration;

1968